메뉴 건너뛰기




Volumn 30, Issue , 2016, Pages 39-45

The transcription factor BATF modulates cytokine-mediated responses in T cells

Author keywords

AP 1; Asthma; BATF; T cells

Indexed keywords

BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; BATF PROTEIN, HUMAN; CYTOKINE;

EID: 84960146007     PISSN: 13596101     EISSN: 18790305     Source Type: Journal    
DOI: 10.1016/j.cytogfr.2016.03.004     Document Type: Short Survey
Times cited : (27)

References (52)
  • 1
    • 0242691046 scopus 로고    scopus 로고
    • AP-1: a double-edged sword in tumorigenesis
    • [1] Eferl, R., Wagner, E.F., AP-1: a double-edged sword in tumorigenesis. Nat. Rev. Cancer 3 (2003), 859–868.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 859-868
    • Eferl, R.1    Wagner, E.F.2
  • 2
    • 84879689439 scopus 로고    scopus 로고
    • Specificity through cooperation: bATF-IRF interactions control immune-regulatory networks
    • [2] Murphy, T.L., Tussiwand, R., Murphy, K.M., Specificity through cooperation: bATF-IRF interactions control immune-regulatory networks. Nat. Rev. Immunol. 13 (2013), 499–509.
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 499-509
    • Murphy, T.L.1    Tussiwand, R.2    Murphy, K.M.3
  • 3
    • 49649113832 scopus 로고    scopus 로고
    • Multiple facets of junD gene expression are atypical among AP-1 family members
    • [3] Hernandez, J.M., Floyd, D.H., Weilbaecher, K.N., Green, P.L., Boris-Lawrie, K., Multiple facets of junD gene expression are atypical among AP-1 family members. Oncogene 27 (2008), 4757–4767.
    • (2008) Oncogene , vol.27 , pp. 4757-4767
    • Hernandez, J.M.1    Floyd, D.H.2    Weilbaecher, K.N.3    Green, P.L.4    Boris-Lawrie, K.5
  • 4
    • 28544434439 scopus 로고    scopus 로고
    • Fos/AP-1 proteins in bone and the immune system
    • [4] Wagner, E.F., Eferl, R., Fos/AP-1 proteins in bone and the immune system. Immunol. Rev. 208 (2005), 126–140.
    • (2005) Immunol. Rev. , vol.208 , pp. 126-140
    • Wagner, E.F.1    Eferl, R.2
  • 5
    • 56449097442 scopus 로고    scopus 로고
    • Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic T cell immunity
    • [5] Hildner, K., Edelson, B.T., Purtha, W.E., Diamond, M., Matsushita, H., Kohyama, M., et al. Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic T cell immunity. Science 322 (2008), 1097–1100.
    • (2008) Science , vol.322 , pp. 1097-1100
    • Hildner, K.1    Edelson, B.T.2    Purtha, W.E.3    Diamond, M.4    Matsushita, H.5    Kohyama, M.6
  • 7
    • 77952304784 scopus 로고    scopus 로고
    • Batf coordinates multiple aspects of B and T cell function required for normal antibody responses
    • [7] Betz, B.C., Jordan-Williams, K.L., Wang, C., Kang, S.G., Liao, J., Logan, M.R., et al. Batf coordinates multiple aspects of B and T cell function required for normal antibody responses. J. Exp. Med. 207 (2010), 933–942.
    • (2010) J. Exp. Med. , vol.207 , pp. 933-942
    • Betz, B.C.1    Jordan-Williams, K.L.2    Wang, C.3    Kang, S.G.4    Liao, J.5    Logan, M.R.6
  • 8
    • 79956081339 scopus 로고    scopus 로고
    • The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells
    • [8] Ise, W., Kohyama, M., Schraml, B.U., Zhang, T., Schwer, B., Basu, U., et al. The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells. Nat. Immunol. 12 (2011), 536–543.
    • (2011) Nat. Immunol. , vol.12 , pp. 536-543
    • Ise, W.1    Kohyama, M.2    Schraml, B.U.3    Zhang, T.4    Schwer, B.5    Basu, U.6
  • 9
  • 10
    • 67651001561 scopus 로고    scopus 로고
    • The AP-1 transcription factor Batf controls T(H)17 differentiation
    • [10] Schraml, B.U., Hildner, K., Ise, W., Lee, W.L., Smith, W.A., Solomon, B., et al. The AP-1 transcription factor Batf controls T(H)17 differentiation. Nature 460 (2009), 405–409.
    • (2009) Nature , vol.460 , pp. 405-409
    • Schraml, B.U.1    Hildner, K.2    Ise, W.3    Lee, W.L.4    Smith, W.A.5    Solomon, B.6
  • 11
    • 84891735920 scopus 로고    scopus 로고
    • The activating protein 1 transcription factor basic leucine zipper transcription factor, ATF-like (BATF), regulates lymphocyte- and mast cell-driven immune responses in the setting of allergic asthma
    • e9
    • [11] Ubel, C., Sopel, N., Graser, A., Hildner, K., Reinhardt, C., Zimmermann, T., et al. The activating protein 1 transcription factor basic leucine zipper transcription factor, ATF-like (BATF), regulates lymphocyte- and mast cell-driven immune responses in the setting of allergic asthma. J. Allergy Clin. Immunol. 133 (2014), 198–206 e9.
    • (2014) J. Allergy Clin. Immunol. , vol.133 , pp. 198-206
    • Ubel, C.1    Sopel, N.2    Graser, A.3    Hildner, K.4    Reinhardt, C.5    Zimmermann, T.6
  • 12
    • 84902277611 scopus 로고    scopus 로고
    • IRF4 and BATF are critical for CD8(+) T-cell function following infection with LCMV
    • [12] Grusdat, M., McIlwain, D.R., Xu, H.C., Pozdeev, V.I., Knievel, J., Crome, S.Q., et al. IRF4 and BATF are critical for CD8(+) T-cell function following infection with LCMV. Cell Death Differ. 21 (2014), 1050–1060.
    • (2014) Cell Death Differ. , vol.21 , pp. 1050-1060
    • Grusdat, M.1    McIlwain, D.R.2    Xu, H.C.3    Pozdeev, V.I.4    Knievel, J.5    Crome, S.Q.6
  • 13
    • 84897067040 scopus 로고    scopus 로고
    • The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells
    • [13] Kurachi, M., Barnitz, R.A., Yosef, N., Odorizzi, P.M., DiIorio, M.A., Lemieux, M.E., et al. The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells. Nat. Immunol. 15 (2014), 373–383.
    • (2014) Nat. Immunol. , vol.15 , pp. 373-383
    • Kurachi, M.1    Barnitz, R.A.2    Yosef, N.3    Odorizzi, P.M.4    DiIorio, M.A.5    Lemieux, M.E.6
  • 15
    • 0029583226 scopus 로고
    • B-ATF: a novel human bZIP protein that associates with members of the AP-1 transcription factor family
    • [15] Dorsey, M.J., Tae, H.J., Sollenberger, K.G., Mascarenhas, N.T., Johansen, L.M., Taparowsky, E.J., B-ATF: a novel human bZIP protein that associates with members of the AP-1 transcription factor family. Oncogene 11 (1995), 2255–2265.
    • (1995) Oncogene , vol.11 , pp. 2255-2265
    • Dorsey, M.J.1    Tae, H.J.2    Sollenberger, K.G.3    Mascarenhas, N.T.4    Johansen, L.M.5    Taparowsky, E.J.6
  • 16
    • 0029988080 scopus 로고    scopus 로고
    • SFA-2, a novel bZIP transcription factor induced by human T-cell leukemia virus type I, is highly expressed in mature lymphocytes
    • [16] Hasegawa, H., Utsunomiya, Y., Kishimoto, K., Tange, Y., Yasukawa, M., Fujita, S., SFA-2, a novel bZIP transcription factor induced by human T-cell leukemia virus type I, is highly expressed in mature lymphocytes. Biochem. Biophys. Res. Commun. 222 (1996), 164–170.
    • (1996) Biochem. Biophys. Res. Commun. , vol.222 , pp. 164-170
    • Hasegawa, H.1    Utsunomiya, Y.2    Kishimoto, K.3    Tange, Y.4    Yasukawa, M.5    Fujita, S.6
  • 17
    • 0000448132 scopus 로고    scopus 로고
    • B-ATF functions as a negative regulator of AP-1 mediated transcription and blocks cellular transformation by Ras and Fos
    • [17] Echlin, D.R., Tae, H.J., Mitin, N., Taparowsky, E.J., B-ATF functions as a negative regulator of AP-1 mediated transcription and blocks cellular transformation by Ras and Fos. Oncogene 19 (2000), 1752–1763.
    • (2000) Oncogene , vol.19 , pp. 1752-1763
    • Echlin, D.R.1    Tae, H.J.2    Mitin, N.3    Taparowsky, E.J.4
  • 18
    • 0035007711 scopus 로고    scopus 로고
    • Characterization of murine BATF: a negative regulator of activator protein-1 activity in the thymus
    • [18] Williams, K.L., Nanda, I., Lyons, G.E., Kuo, C.T., Schmid, M., Leiden, J.M., et al. Characterization of murine BATF: a negative regulator of activator protein-1 activity in the thymus. Eur. J. Immunol. 31 (2001), 1620–1627.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1620-1627
    • Williams, K.L.1    Nanda, I.2    Lyons, G.E.3    Kuo, C.T.4    Schmid, M.5    Leiden, J.M.6
  • 19
    • 84863229585 scopus 로고    scopus 로고
    • A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage
    • [19] Wang, J., Sun, Q., Morita, Y., Jiang, H., Gross, A., Lechel, A., et al. A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage. Cell 148 (2012), 1001–1014.
    • (2012) Cell , vol.148 , pp. 1001-1014
    • Wang, J.1    Sun, Q.2    Morita, Y.3    Jiang, H.4    Gross, A.5    Lechel, A.6
  • 20
    • 79952829918 scopus 로고    scopus 로고
    • Batf promotes growth arrest and terminal differentiation of mouse myeloid leukemia cells
    • [20] Liao, J., Humphrey, S.E., Poston, S., Taparowsky, E.J., Batf promotes growth arrest and terminal differentiation of mouse myeloid leukemia cells. Mol. Cancer Res. 9 (2011), 350–363.
    • (2011) Mol. Cancer Res. , vol.9 , pp. 350-363
    • Liao, J.1    Humphrey, S.E.2    Poston, S.3    Taparowsky, E.J.4
  • 22
    • 84877752694 scopus 로고    scopus 로고
    • IL-6 activated integrated BATF/IRF4 functions in lymphocytes are T-bet-independent and reversed by subcutaneous immunotherapy
    • [22] Koch, S., Mousset, S., Graser, A., Reppert, S., Übel, C., Reinhardt, C., et al. IL-6 activated integrated BATF/IRF4 functions in lymphocytes are T-bet-independent and reversed by subcutaneous immunotherapy. Sci. Rep., 3, 2013.
    • (2013) Sci. Rep. , vol.3
    • Koch, S.1    Mousset, S.2    Graser, A.3    Reppert, S.4    Übel, C.5    Reinhardt, C.6
  • 23
    • 84896723576 scopus 로고    scopus 로고
    • Excess IL-1 signaling enhances the development of Th17 cells by downregulating TGF-beta-induced Foxp3 expression
    • [23] Ikeda, S., Saijo, S., Murayama, M.A., Shimizu, K., Akitsu, A., Iwakura, Y., Excess IL-1 signaling enhances the development of Th17 cells by downregulating TGF-beta-induced Foxp3 expression. J. Immunol. 192 (2014), 1449–1458.
    • (2014) J. Immunol. , vol.192 , pp. 1449-1458
    • Ikeda, S.1    Saijo, S.2    Murayama, M.A.3    Shimizu, K.4    Akitsu, A.5    Iwakura, Y.6
  • 24
    • 80052605201 scopus 로고    scopus 로고
    • Basic leucine zipper transcription factor, ATF-like (BATF) regulates epigenetically and energetically effector CD8 T-cell differentiation via Sirt1 expression
    • [24] Kuroda, S., Yamazaki, M., Abe, M., Sakimura, K., Takayanagi, H., Iwai, Y., Basic leucine zipper transcription factor, ATF-like (BATF) regulates epigenetically and energetically effector CD8 T-cell differentiation via Sirt1 expression. Proc. Natl. Acad. Sci. U. S. A. 108 (2011), 14885–14889.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 14885-14889
    • Kuroda, S.1    Yamazaki, M.2    Abe, M.3    Sakimura, K.4    Takayanagi, H.5    Iwai, Y.6
  • 25
    • 0041829108 scopus 로고    scopus 로고
    • Phosphorylation of BATF regulates DNA binding: a novel mechanism for AP-1 (activator protein-1) regulation
    • [25] Deppmann, C.D., Thornton, T.M., Utama, F.E., Taparowsky, E.J., Phosphorylation of BATF regulates DNA binding: a novel mechanism for AP-1 (activator protein-1) regulation. Biochem. J. 374 (2003), 423–431.
    • (2003) Biochem. J. , vol.374 , pp. 423-431
    • Deppmann, C.D.1    Thornton, T.M.2    Utama, F.E.3    Taparowsky, E.J.4
  • 26
  • 27
    • 30944434637 scopus 로고    scopus 로고
    • Direct manipulation of activator protein-1 controls thymocyte proliferation in vitro
    • [27] Thornton, T.M., Zullo, A.J., Williams, K.L., Taparowsky, E.J., Direct manipulation of activator protein-1 controls thymocyte proliferation in vitro. Eur. J. Immunol. 36 (2006), 160–169.
    • (2006) Eur. J. Immunol. , vol.36 , pp. 160-169
    • Thornton, T.M.1    Zullo, A.J.2    Williams, K.L.3    Taparowsky, E.J.4
  • 28
    • 84861564657 scopus 로고    scopus 로고
    • Overexpression of Batf induces an apoptotic defect and an associated lymphoproliferative disorder in mice
    • [28] Logan, M.R., Jordan-Williams, K.L., Poston, S., Liao, J., Taparowsky, E.J., Overexpression of Batf induces an apoptotic defect and an associated lymphoproliferative disorder in mice. Cell Death Dis., 3, 2012, e310.
    • (2012) Cell Death Dis. , vol.3 , pp. e310
    • Logan, M.R.1    Jordan-Williams, K.L.2    Poston, S.3    Liao, J.4    Taparowsky, E.J.5
  • 29
    • 33845963552 scopus 로고    scopus 로고
    • Sensitivity of NK1.1-negative NKT cells to transgenic BATF defines a role for activator protein-1 in the expansion and maturation of immature NKT cells in the thymus
    • [29] Zullo, A.J., Benlagha, K., Bendelac, A., Taparowsky, E.J., Sensitivity of NK1.1-negative NKT cells to transgenic BATF defines a role for activator protein-1 in the expansion and maturation of immature NKT cells in the thymus. J. Immunol. 178 (2007), 58–66.
    • (2007) J. Immunol. , vol.178 , pp. 58-66
    • Zullo, A.J.1    Benlagha, K.2    Bendelac, A.3    Taparowsky, E.J.4
  • 30
    • 84867861268 scopus 로고    scopus 로고
    • BATF-JUN is critical for IRF4-mediated transcription in T cells
    • [30] Li, P., Spolski, R., Liao, W., Wang, L., Murphy, T.L., Murphy, K.M., et al. BATF-JUN is critical for IRF4-mediated transcription in T cells. Nature 490 (2012), 543–546.
    • (2012) Nature , vol.490 , pp. 543-546
    • Li, P.1    Spolski, R.2    Liao, W.3    Wang, L.4    Murphy, T.L.5    Murphy, K.M.6
  • 31
    • 79956106132 scopus 로고    scopus 로고
    • A BATF-ling connection between B cells and follicular helper T cells
    • [31] Ellyard, J.I., Vinuesa, C.G., A BATF-ling connection between B cells and follicular helper T cells. Nat. Immunol. 12 (2011), 519–520.
    • (2011) Nat. Immunol. , vol.12 , pp. 519-520
    • Ellyard, J.I.1    Vinuesa, C.G.2
  • 32
    • 49649105526 scopus 로고    scopus 로고
    • Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells
    • [32] Haining, W.N., Ebert, B.L., Subrmanian, A., Wherry, E.J., Eichbaum, Q., Evans, J.W., et al. Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells. J. Immunol. 181 (2008), 1859–1868.
    • (2008) J. Immunol. , vol.181 , pp. 1859-1868
    • Haining, W.N.1    Ebert, B.L.2    Subrmanian, A.3    Wherry, E.J.4    Eichbaum, Q.5    Evans, J.W.6
  • 33
    • 77957781776 scopus 로고    scopus 로고
    • Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF
    • [33] Quigley, M., Pereyra, F., Nilsson, B., Porichis, F., Fonseca, C., Eichbaum, Q., et al. Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF. Nat. Med. 16 (2010), 1147–1151.
    • (2010) Nat. Med. , vol.16 , pp. 1147-1151
    • Quigley, M.1    Pereyra, F.2    Nilsson, B.3    Porichis, F.4    Fonseca, C.5    Eichbaum, Q.6
  • 34
    • 84920971293 scopus 로고    scopus 로고
    • Inducible RNAi in vivo reveals that the transcription factor BATF is required to initiate but not maintain CD8+ T-cell effector differentiation
    • [34] Godec, J., Cowley, G.S., Barnitz, R.A., Root, D.E., Sharpe, A.H., Haining, W.N., Inducible RNAi in vivo reveals that the transcription factor BATF is required to initiate but not maintain CD8+ T-cell effector differentiation. Proc. Natl. Acad. Sci. U. S. A. 112 (2015), 512–517.
    • (2015) Proc. Natl. Acad. Sci. U. S. A. , vol.112 , pp. 512-517
    • Godec, J.1    Cowley, G.S.2    Barnitz, R.A.3    Root, D.E.4    Sharpe, A.H.5    Haining, W.N.6
  • 35
    • 84876942120 scopus 로고    scopus 로고
    • T cells in asthma: influences of genetics, environment, and T-cell plasticity
    • quiz 75
    • [35] Lloyd, C.M., Saglani, S., T cells in asthma: influences of genetics, environment, and T-cell plasticity. J. Allergy Clin. Immunol. 131 (2013), 1267–1274 quiz 75.
    • (2013) J. Allergy Clin. Immunol. , vol.131 , pp. 1267-1274
    • Lloyd, C.M.1    Saglani, S.2
  • 36
    • 67349216357 scopus 로고    scopus 로고
    • Autoimmune T cell responses in the central nervous system
    • [36] Goverman, J., Autoimmune T cell responses in the central nervous system. Nat. Rev. Immunol. 9 (2009), 393–407.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 393-407
    • Goverman, J.1
  • 37
    • 0037216498 scopus 로고    scopus 로고
    • Increased expression of interleukin 17 in inflammatory bowel disease
    • [37] Fujino, S., Andoh, A., Bamba, S., Ogawa, A., Hata, K., Araki, Y., et al. Increased expression of interleukin 17 in inflammatory bowel disease. Gut 52 (2003), 65–70.
    • (2003) Gut , vol.52 , pp. 65-70
    • Fujino, S.1    Andoh, A.2    Bamba, S.3    Ogawa, A.4    Hata, K.5    Araki, Y.6
  • 38
    • 84882771510 scopus 로고    scopus 로고
    • Increased IL-17A secreting CD4+ T cells, serum IL-17 levels and exhaled nitric oxide are correlated with childhood asthma severity
    • [38] Chien, J.W., Lin, C.Y., Yang, K.D., Lin, C.H., Kao, J.K., Tsai, Y.G., Increased IL-17A secreting CD4+ T cells, serum IL-17 levels and exhaled nitric oxide are correlated with childhood asthma severity. Clin. Exp. Allergy: J. British Soc. Allergy Clin. Immunol. 43 (2013), 1018–1026.
    • (2013) Clin. Exp. Allergy: J. British Soc. Allergy Clin. Immunol. , vol.43 , pp. 1018-1026
    • Chien, J.W.1    Lin, C.Y.2    Yang, K.D.3    Lin, C.H.4    Kao, J.K.5    Tsai, Y.G.6
  • 39
    • 84859137202 scopus 로고    scopus 로고
    • Activin A and TGF-beta promote T(H) 9 cell-mediated pulmonary allergic pathology
    • (e3)
    • [39] Jones, C.P., Gregory, L.G., Causton, B., Campbell, G.A., Lloyd, C.M., Activin A and TGF-beta promote T(H) 9 cell-mediated pulmonary allergic pathology. J. Allergy Clin. Immunol. 129 (2012), 1000–1010 (e3).
    • (2012) J. Allergy Clin. Immunol. , vol.129 , pp. 1000-1010
    • Jones, C.P.1    Gregory, L.G.2    Causton, B.3    Campbell, G.A.4    Lloyd, C.M.5
  • 40
    • 13944249962 scopus 로고    scopus 로고
    • Mast cells in the development of adaptive immune responses
    • [40] Galli, S.J., Nakae, S., Tsai, M., Mast cells in the development of adaptive immune responses. Nat. Immunol. 6 (2005), 135–142.
    • (2005) Nat. Immunol. , vol.6 , pp. 135-142
    • Galli, S.J.1    Nakae, S.2    Tsai, M.3
  • 41
    • 77954115305 scopus 로고    scopus 로고
    • Mast cells in allergy and infection: versatile effector and regulatory cells in innate and adaptive immunity
    • [41] Galli, S.J., Tsai, M., Mast cells in allergy and infection: versatile effector and regulatory cells in innate and adaptive immunity. Eur. J. Immunol. 40 (2010), 1843–1851.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 1843-1851
    • Galli, S.J.1    Tsai, M.2
  • 42
    • 20144375594 scopus 로고    scopus 로고
    • The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo
    • [42] Doganci, A., Eigenbrod, T., Krug, N., De Sanctis, G.T., Hausding, M., Erpenbeck, V.J., et al. The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo. J. Clin. Invest. 115 (2005), 313–325.
    • (2005) J. Clin. Invest. , vol.115 , pp. 313-325
    • Doganci, A.1    Eigenbrod, T.2    Krug, N.3    De Sanctis, G.T.4    Hausding, M.5    Erpenbeck, V.J.6
  • 43
    • 84922273103 scopus 로고    scopus 로고
    • The immunology of asthma
    • [43] Lambrecht, B.N., Hammad, H., The immunology of asthma. Nat. Immunol. 16 (2015), 45–56.
    • (2015) Nat. Immunol. , vol.16 , pp. 45-56
    • Lambrecht, B.N.1    Hammad, H.2
  • 44
    • 33644641356 scopus 로고    scopus 로고
    • Determinants of lymphoid-myeloid lineage diversification
    • [44] Laiosa, C.V., Stadtfeld, M., Graf, T., Determinants of lymphoid-myeloid lineage diversification. Annu. Rev. Immunol. 24 (2006), 705–738.
    • (2006) Annu. Rev. Immunol. , vol.24 , pp. 705-738
    • Laiosa, C.V.1    Stadtfeld, M.2    Graf, T.3
  • 45
    • 47949107183 scopus 로고    scopus 로고
    • The development of allergic inflammation
    • [45] Galli, S.J., Tsai, M., Piliponsky, A.M., The development of allergic inflammation. Nature 454 (2008), 445–454.
    • (2008) Nature , vol.454 , pp. 445-454
    • Galli, S.J.1    Tsai, M.2    Piliponsky, A.M.3
  • 46
    • 0030810155 scopus 로고    scopus 로고
    • The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4T cells
    • [46] Zheng, W., Flavell, R.A., The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4T cells. Cell 89 (1997), 587–596.
    • (1997) Cell , vol.89 , pp. 587-596
    • Zheng, W.1    Flavell, R.A.2
  • 47
    • 0037059509 scopus 로고    scopus 로고
    • Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet
    • [47] Finotto, S., Neurath, M.F., Glickman, J.N., Qin, S., Lehr, H.A., Green, F.H., et al. Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet. Science 295 (2002), 336–338.
    • (2002) Science , vol.295 , pp. 336-338
    • Finotto, S.1    Neurath, M.F.2    Glickman, J.N.3    Qin, S.4    Lehr, H.A.5    Green, F.H.6
  • 48
    • 28544432829 scopus 로고    scopus 로고
    • CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function
    • [48] Lewkowich, I.P., Herman, N.S., Schleifer, K.W., Dance, M.P., Chen, B.L., Dienger, K.M., et al. CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function. J. Exp. Med. 202 (2005), 1549–1561.
    • (2005) J. Exp. Med. , vol.202 , pp. 1549-1561
    • Lewkowich, I.P.1    Herman, N.S.2    Schleifer, K.W.3    Dance, M.P.4    Chen, B.L.5    Dienger, K.M.6
  • 49
    • 71849089195 scopus 로고    scopus 로고
    • Coexpression of TGF-beta1 and IL-10 enables regulatory T cells to completely suppress airway hyperreactivity
    • [49] Presser, K., Schwinge, D., Wegmann, M., Huber, S., Schmitt, S., Quaas, A., et al. Coexpression of TGF-beta1 and IL-10 enables regulatory T cells to completely suppress airway hyperreactivity. J. Immunol. 181 (2008), 7751–7758.
    • (2008) J. Immunol. , vol.181 , pp. 7751-7758
    • Presser, K.1    Schwinge, D.2    Wegmann, M.3    Huber, S.4    Schmitt, S.5    Quaas, A.6
  • 50
    • 73949133135 scopus 로고    scopus 로고
    • Cutting edge: the Th1 response inhibits the generation of peripheral regulatory T cells
    • [50] Caretto, D., Katzman, S.D., Villarino, A.V., Gallo, E., Abbas, A.K., Cutting edge: the Th1 response inhibits the generation of peripheral regulatory T cells. J. Immunol. 184 (2010), 30–34.
    • (2010) J. Immunol. , vol.184 , pp. 30-34
    • Caretto, D.1    Katzman, S.D.2    Villarino, A.V.3    Gallo, E.4    Abbas, A.K.5
  • 51
    • 34247564147 scopus 로고    scopus 로고
    • Nonredundant roles for Stat5a/b in directly regulating Foxp3
    • [51] Yao, Z., Kanno, Y., Kerenyi, M., Stephens, G., Durant, L., Watford, W.T., et al. Nonredundant roles for Stat5a/b in directly regulating Foxp3. Blood 109 (2007), 4368–4375.
    • (2007) Blood , vol.109 , pp. 4368-4375
    • Yao, Z.1    Kanno, Y.2    Kerenyi, M.3    Stephens, G.4    Durant, L.5    Watford, W.T.6
  • 52
    • 80052272692 scopus 로고    scopus 로고
    • Pathophysiology of asthma: what has our current understanding taught us about new therapeutic approaches
    • [52] Holgate, S.T., Pathophysiology of asthma: what has our current understanding taught us about new therapeutic approaches. J. Allergy Clin. Immunol. 128 (2011), 495–505.
    • (2011) J. Allergy Clin. Immunol. , vol.128 , pp. 495-505
    • Holgate, S.T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.