Basic leucine zipper transcription factor, ATF-like (BATF) regulates epigenetically and energetically effector CD8 T-cell differentiation via Sirt1 expression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 36, 2011, Pages 14885-14889

  Kuroda, Shoko ^a   Yamazaki, Maya ^b   Abe, Manabu ^b   Sakimura, Kenji ^b   Takayanagi, Hiroshi ^a,c   Iwai, Yoshiko ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NIIGATA UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

AP 1; Chromatin remodeling; Glycolysis; Oxidative phosphorylation

Indexed keywords

ADENOSINE TRIPHOSPHATE; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; HISTONE; INTERLEUKIN 12; NICOTINAMIDE ADENINE DINUCLEOTIDE; PROTEIN C JUN; SIRTUIN 1;

ANIMAL CELL; ARTICLE; CD8+ T LYMPHOCYTE; CELL SURVIVAL; CONTROLLED STUDY; EFFECTOR CELL; ENERGY YIELD; EPIGENETICS; HISTONE ACETYLATION; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ACETYLATION; ADENOSINE TRIPHOSPHATE; ANIMALS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CD8-POSITIVE T-LYMPHOCYTES; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENETIC LOCI; HISTONES; INTERLEUKIN-12; MICE; MICE, KNOCKOUT; NAD; PROTEIN MULTIMERIZATION; SIRTUIN 1;

EID: 80052605201     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1105133108     Document Type: Article

References (31)

1. Harty JT, Badovinac VP (2008) Shaping and reshaping CD8+ T-cell memory. Nat Rev Immunol 8:107-119. (Pubitemid 351161304)
2. + T cell differentiation during viral infection. Immunity 27:393-405.
3. Williams MA, Bevan MJ (2007) Effector and memory CTL differentiation. Annu Rev Immunol 25:171-192. (Pubitemid 46697906)
4. Jones RG, Thompson CB (2007) Revving the engine: Signal transduction fuels T cell activation. Immunity 27:173-178. (Pubitemid 47284920)
5. Curtsinger JM, Mescher MF (2010) Inflammatory cytokines as a third signal for T cell activation. Curr Opin Immunol 22:333-340.
6. Mescher MF, et al. (2006) Signals required for programming effector and memory development by CD8+ T cells. Immunol Rev 211:81-92. (Pubitemid 43882963)
7. Dorsey MJ, et al. (1995) B-ATF: A novel human bZIP protein that associates with members of the AP-1 transcription factor family. Oncogene 11:2255-2265. (Pubitemid 26008401)
8. Hasegawa H, et al. (1996) SFA-2, a novel bZIP transcription factor induced by human T-cell leukemia virus type I, is highly expressed in mature lymphocytes. Biochem Biophys Res Commun 222:164-170. (Pubitemid 26152222)
9. Echlin DR, Tae HJ, Mitin N, Taparowsky EJ (2000) B-ATF functions as a negative regulator of AP-1 mediated transcription and blocks cellular transformation by Ras and Fos. Oncogene 19:1752-1763. (Pubitemid 30200981)
10. (H)17 differentiation. Nature 460:405-409.
11. Betz BC, et al. (2010) Batf coordinates multiple aspects of B and T cell function required for normal antibody responses. J Exp Med 207:933-942.
12. Hawiger D, et al. (2001) Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med 194:769-779. (Pubitemid 32983013)
13. Bonifaz L, et al. (2002) Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance. J Exp Med 196:1627-1638. (Pubitemid 36026474)
14. + T cell proliferation. PLoS ONE 3:e2404.
15. Steinman RM, Banchereau J (2007) Taking dendritic cells into medicine. Nature 449: 419-426. (Pubitemid 47509552)
16. Cella M, et al. (1996) Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J Exp Med 184:747-752. (Pubitemid 26324129)
17. Koch F, et al. (1996) High level IL-12 production by murine dendritic cells: Upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10. J Exp Med 184:741-746. (Pubitemid 26324128)
18. Dispirito JR, Shen H (2010) Histone acetylation at the single-cell level: A marker of memory CD8+ T cell differentiation and functionality. J Immunol 184:4631-4636.
19. +) T cell fates via the graded expression of T-bet transcription factor. Immunity 27:281-295.
20. + T cell fate by regulating the expression of transcription factors T-bet and Eomesodermin. Immunity 32:67-78.
21. Brooks CL, Gu W (2009) How does SIRT1 affect metabolism, senescence and cancer? Nat Rev Cancer 9:123-128.
22. Imai S, Guarente L (2010) Ten years of NAD-dependent SIR2 family deacetylases: Implications for metabolic diseases. Trends Pharmacol Sci 31:212-220.
23. Lin SJ, Guarente L (2003) Nicotinamide adenine dinucleotide, a metabolic regulator of transcription, longevity and disease. Curr Opin Cell Biol 15:241-246.
24. + precursor vitamins in human nutrition. Annu Rev Nutr 28:115-130.
25. + depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE. PLoS ONE 4:e7897.
26. Zhang J, et al. (2009) The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice. J Clin Invest 119:3048-3058.
27. + T cells to apoptosis in vivo. J Immunol 169: 3760-3770.
28. + T cell fate coupled by T-bet and eomesodermin. Nat Immunol 6:1236-1244.
29. Szabo SJ, et al. (2000) A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100:655-669.
30. + T cells shows that PD-1 inhibits T cell function by upregulating BATF. Nat Med 16:1147-1151.
31. +) T cell responses during chronic infection. Nat Immunol 12:663-671.