-
1
-
-
84857502654
-
Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial
-
Rosell R, Carcereny E, Gervais R, et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol 2012;13:239-46.
-
(2012)
Lancet Oncol
, vol.13
, pp. 239-246
-
-
Rosell, R.1
Carcereny, E.2
Gervais, R.3
-
2
-
-
84884736973
-
Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations
-
Sequist LV, Yang JC, Yamamoto N, et al. Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations. J Clin Oncol 2013;31:3327-34.
-
(2013)
J Clin Oncol
, vol.31
, pp. 3327-3334
-
-
Sequist, L.V.1
Yang, J.C.2
Yamamoto, N.3
-
3
-
-
84893080787
-
Epidermal growth factor receptor inhibition in mutation-positive non-small-cell lung cancer: is afatinib better or simply newer?
-
Langer CJ. Epidermal growth factor receptor inhibition in mutation-positive non-small-cell lung cancer: is afatinib better or simply newer? J Clin Oncol 2013;31:3303-6.
-
(2013)
J Clin Oncol
, vol.31
, pp. 3303-3306
-
-
Langer, C.J.1
-
4
-
-
84877100240
-
Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR-mutant lung cancers
-
Yu HA, Arcila ME, Rekhtman N, et al. Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR-mutant lung cancers. Clin Cancer Res 2013;19:2240-7.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 2240-2247
-
-
Yu, H.A.1
Arcila, M.E.2
Rekhtman, N.3
-
5
-
-
18244371651
-
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
-
Pao W, Miller VA, Politi KA, et al. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med 2005;2:e73.
-
(2005)
PLoS Med
, vol.2
, pp. e73
-
-
Pao, W.1
Miller, V.A.2
Politi, K.A.3
-
6
-
-
77950460014
-
Acquired resistance to gefitinib: the contribution of mechanisms other than the T790M, MET, and HGF status
-
Onitsuka T, Uramoto H, Nose N, et al. Acquired resistance to gefitinib: the contribution of mechanisms other than the T790M, MET, and HGF status. Lung Cancer 2010;68:198-203.
-
(2010)
Lung Cancer
, vol.68
, pp. 198-203
-
-
Onitsuka, T.1
Uramoto, H.2
Nose, N.3
-
7
-
-
33750302365
-
Analysis of epidermal growth factor receptor gene mutation in patients with non-small cell lung cancer and acquired resistance to gefitinib
-
Kosaka T, Yatabe Y, Endoh H, et al. Analysis of epidermal growth factor receptor gene mutation in patients with non-small cell lung cancer and acquired resistance to gefitinib. Clin Cancer Res 2006;12:5764-9.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5764-5769
-
-
Kosaka, T.1
Yatabe, Y.2
Endoh, H.3
-
8
-
-
84890018871
-
Emerging paradigms in the development of resistance to tyrosine kinase inhibitors in lung cancer
-
Gainor JF, Shaw AT. Emerging paradigms in the development of resistance to tyrosine kinase inhibitors in lung cancer. J Clin Oncol 2013;31:3987-96.
-
(2013)
J Clin Oncol
, vol.31
, pp. 3987-3996
-
-
Gainor, J.F.1
Shaw, A.T.2
-
9
-
-
84908371107
-
Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor
-
Finlay MR, Anderton M, Ashton S, et al. Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor. J Med Chem 2014;57:8249-67.
-
(2014)
J Med Chem
, vol.57
, pp. 8249-8267
-
-
Finlay, M.R.1
Anderton, M.2
Ashton, S.3
-
10
-
-
84906911022
-
Dual inhibition of EGFR with afatinib and cetuximab in kinase inhibitor-resistant EGFR-mutant lung cancer with and without T790M mutations
-
Janjigian YY, Smit EF, Groen HJ, et al. Dual inhibition of EGFR with afatinib and cetuximab in kinase inhibitor-resistant EGFR-mutant lung cancer with and without T790M mutations. Cancer Discov 2014;4:1036-45.
-
(2014)
Cancer Discov
, vol.4
, pp. 1036-1045
-
-
Janjigian, Y.Y.1
Smit, E.F.2
Groen, H.J.3
-
11
-
-
79952264325
-
Pretreatment EGFR T790M mutation and BRCA1 mRNA expression in erlotinib-treated advanced non-small-cell lung cancer patients with EGFR mutations
-
Rosell R, Molina MA, Costa C, et al. Pretreatment EGFR T790M mutation and BRCA1 mRNA expression in erlotinib-treated advanced non-small-cell lung cancer patients with EGFR mutations. Clin Cancer Res 2011;17:1160-8.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 1160-1168
-
-
Rosell, R.1
Molina, M.A.2
Costa, C.3
-
12
-
-
84942568700
-
Clinical approaches to treat patients with non-small cell lung cancer and epidermal growth factor receptor tyrosine kinase inhibitor acquired resistance
-
Tartarone A, Lerose R. Clinical approaches to treat patients with non-small cell lung cancer and epidermal growth factor receptor tyrosine kinase inhibitor acquired resistance. Ther Adv Respir Dis 2015;9:242-50.
-
(2015)
Ther Adv Respir Dis
, vol.9
, pp. 242-250
-
-
Tartarone, A.1
Lerose, R.2
-
13
-
-
84928739294
-
AZD9291 in EGFR inhibitor-resistant non-small-cell lung cancer
-
Jänne PA, Yang JC, Kim DW, et al. AZD9291 in EGFR inhibitor-resistant non-small-cell lung cancer. N Engl J Med 2015;372:1689-99.
-
(2015)
N Engl J Med
, vol.372
, pp. 1689-1699
-
-
Jänne, P.A.1
Yang, J.C.2
Kim, D.W.3
-
14
-
-
84928746232
-
Rociletinib in EGFR-mutated non-small-cell lung cancer
-
Sequist LV, Soria JC, Goldman JW, et al. Rociletinib in EGFR-mutated non-small-cell lung cancer. N Engl J Med 2015;372:1700-9.
-
(2015)
N Engl J Med
, vol.372
, pp. 1700-1709
-
-
Sequist, L.V.1
Soria, J.C.2
Goldman, J.W.3
-
15
-
-
84871096641
-
Managing chronic myeloid leukemia patients intolerant to tyrosine kinase inhibitor therapy
-
Deangelo DJ. Managing chronic myeloid leukemia patients intolerant to tyrosine kinase inhibitor therapy. Blood Cancer J 2012;2:e95.
-
(2012)
Blood Cancer J
, vol.2
, pp. e95
-
-
Deangelo, D.J.1
-
16
-
-
84960095399
-
-
[prescribing information]. East Hanover, NJ: Novartis Pharmaceuticals Corporation
-
Zykadia™ (ceritinib) [prescribing information]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2014.
-
(2014)
Zykadia™ (ceritinib)
-
-
-
17
-
-
84906254433
-
-
[prescribing information]. Pfizer, Inc: New York, NY
-
Xalkori® (crizotinib) [prescribing information]. Pfizer, Inc: New York, NY; 2013.
-
(2013)
Xalkori® (crizotinib)
-
-
-
18
-
-
84865074467
-
Management of metabolic effects associated with anticancer agents targeting the PI3K-Akt-mTOR pathway
-
Busaidy NL, Farooki A, Dowlati A, et al. Management of metabolic effects associated with anticancer agents targeting the PI3K-Akt-mTOR pathway. J Clin Oncol 2012;30:2919-28.
-
(2012)
J Clin Oncol
, vol.30
, pp. 2919-2928
-
-
Busaidy, N.L.1
Farooki, A.2
Dowlati, A.3
-
19
-
-
58849155132
-
Mechanism and management of AKT inhibitor-induced hyperglycemia
-
Crouthamel MC, Kahana JA, Korenchuk S, et al. Mechanism and management of AKT inhibitor-induced hyperglycemia. Clin Cancer Res 2009;15:217-25.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 217-225
-
-
Crouthamel, M.C.1
Kahana, J.A.2
Korenchuk, S.3
-
20
-
-
84879799563
-
Understanding, recognizing, and managing toxicities of targeted anticancer therapies
-
Dy GK, Adjei AA. Understanding, recognizing, and managing toxicities of targeted anticancer therapies. CA Cancer J Clin 2013;63:249-79.
-
(2013)
CA Cancer J Clin
, vol.63
, pp. 249-279
-
-
Dy, G.K.1
Adjei, A.A.2
-
21
-
-
84867800328
-
Rapid amelioration of hyperglycemia facilitated by dasatinib in a chronic myeloid leukemia patient with type 2 diabetes mellitus
-
Ono K, Suzushima H, Watanabe Y, et al. Rapid amelioration of hyperglycemia facilitated by dasatinib in a chronic myeloid leukemia patient with type 2 diabetes mellitus. Intern Med 2012;51:2763-6.
-
(2012)
Intern Med
, vol.51
, pp. 2763-2766
-
-
Ono, K.1
Suzushima, H.2
Watanabe, Y.3
-
22
-
-
14744281398
-
Imatinib and regression of type 2 diabetes
-
Veneri D, Franchini M, Bonora E. Imatinib and regression of type 2 diabetes. N Engl J Med 2005;352:1049-50.
-
(2005)
N Engl J Med
, vol.352
, pp. 1049-1050
-
-
Veneri, D.1
Franchini, M.2
Bonora, E.3
-
23
-
-
84899082524
-
Tyrosine kinase inhibitor sunitinib allows insulin independence in long-standing type 1 diabetes
-
Huda MS, Amiel SA, Ross P, et al. Tyrosine kinase inhibitor sunitinib allows insulin independence in long-standing type 1 diabetes. Diabetes Care 2014;37:e87-8.
-
(2014)
Diabetes Care
, vol.37
, pp. e87-e88
-
-
Huda, M.S.1
Amiel, S.A.2
Ross, P.3
-
24
-
-
84884199186
-
IGF-1R/epithelial-to-mesenchymal transition (EMT) crosstalk suppresses the erlotinib-sensitizing effect of EGFR exon 19 deletion mutations
-
Vazquez-Martin A, Cufí S, Oliveras-Ferraros C, et al. IGF-1R/epithelial-to-mesenchymal transition (EMT) crosstalk suppresses the erlotinib-sensitizing effect of EGFR exon 19 deletion mutations. Sci Rep 2013;3:2560.
-
(2013)
Sci Rep
, vol.3
, pp. 2560
-
-
Vazquez-Martin, A.1
Cufí, S.2
Oliveras-Ferraros, C.3
-
25
-
-
84872591018
-
Resistance to irreversible EGF receptor tyrosine kinase inhibitors through a multistep mechanism involving the IGF1R pathway
-
Cortot AB, Repellin CE, Shimamura T, et al. Resistance to irreversible EGF receptor tyrosine kinase inhibitors through a multistep mechanism involving the IGF1R pathway. Cancer Res 2013;73:834-43.
-
(2013)
Cancer Res
, vol.73
, pp. 834-843
-
-
Cortot, A.B.1
Repellin, C.E.2
Shimamura, T.3
-
26
-
-
84919999219
-
Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes
-
Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2015;38:140-9.
-
(2015)
Diabetes Care
, vol.38
, pp. 140-149
-
-
Inzucchi, S.E.1
Bergenstal, R.M.2
Buse, J.B.3
-
27
-
-
84930465070
-
Standards of medical care in diabetes--2015: summary of revisions
-
Standards of medical care in diabetes--2015: summary of revisions. Diabetes Care 2015;38 Suppl:S4.
-
(2015)
Diabetes Care
, vol.38
, pp. S4
-
-
-
28
-
-
80051978747
-
Use of metformin in the setting of mild-to-moderate renal insufficiency
-
Lipska KJ, Bailey CJ, Inzucchi SE. Use of metformin in the setting of mild-to-moderate renal insufficiency. Diabetes Care 2011;34:1431-7.
-
(2011)
Diabetes Care
, vol.34
, pp. 1431-1437
-
-
Lipska, K.J.1
Bailey, C.J.2
Inzucchi, S.E.3
-
29
-
-
84924084042
-
Metformin use reduction in mild to moderate renal impairment: possible inappropriate curbing of use based on food and drug administration contraindications
-
Flory JH, Hennessy S. Metformin use reduction in mild to moderate renal impairment: possible inappropriate curbing of use based on food and drug administration contraindications. JAMA Intern Med 2015;175:458-9.
-
(2015)
JAMA Intern Med
, vol.175
, pp. 458-459
-
-
Flory, J.H.1
Hennessy, S.2
-
31
-
-
84938887328
-
Rociletinib in EGFR-Mutated Non-Small-Cell Lung Cancer
-
He Y. Rociletinib in EGFR-Mutated Non-Small-Cell Lung Cancer. N Engl J Med 2015;373:578.
-
(2015)
N Engl J Med
, vol.373
, pp. 578
-
-
He, Y.1
-
32
-
-
84922625184
-
Immune-mediated antitumor effect by type 2 diabetes drug, metformin
-
Eikawa S, Nishida M, Mizukami S, et al. Immune-mediated antitumor effect by type 2 diabetes drug, metformin. Proc Natl Acad Sci U S A 2015;112:1809-14.
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 1809-1814
-
-
Eikawa, S.1
Nishida, M.2
Mizukami, S.3
-
34
-
-
84862486430
-
Diabetes and cancer II: role of diabetes medications and influence of shared risk factors
-
Onitilo AA, Engel JM, Glurich I, et al. Diabetes and cancer II: role of diabetes medications and influence of shared risk factors. Cancer Causes Control 2012;23:991-1008.
-
(2012)
Cancer Causes Control
, vol.23
, pp. 991-1008
-
-
Onitilo, A.A.1
Engel, J.M.2
Glurich, I.3
|