Enhanced Apoptosis by Disruption of the STAT3-IκB-ζ Signaling Pathway in Epithelial Cells Induces Sjögren's Syndrome-like Autoimmune Disease

Immunity

Volumn 38, Issue 3, 2013, Pages 450-460

  Okuma, Atsushi ^a   Hoshino, Katsuaki ^b,c,g   Ohba, Tomoyuki ^a   Fukushi, Sawako ^d   Aiba, Setsuya ^d   Akira, Shizuo ^c,e   Ono, Masao ^d   Kaisho, Tsuneyasu ^b,c   Muta, Tatsushi ^a,f  

^a TOHOKU UNIVERSITY   (Japan)

^b Institute of Physical and Chemical Research   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e OSAKA UNIVERSITY   (Japan)

^f Center for Ecosystem Management Adapting to Global Change   (Japan)

^g KAGAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B ZETA PROTEIN; NUCLEIC ACID BINDING PROTEIN; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; DACRYOCYSTITIS; DISEASE ASSOCIATION; EPITHELIUM CELL; FEMALE; HEMATOPOIETIC CELL; LYMPHOCYTIC INFILTRATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SJOEGREN SYNDROME;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; AUTOIMMUNE DISEASES; EPITHELIAL CELLS; FEMALE; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INFLAMMATION; LACRIMAL APPARATUS; LYMPHOCYTES; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; NUCLEAR PROTEINS; SIGNAL TRANSDUCTION; SJOGREN'S SYNDROME; STAT3 TRANSCRIPTION FACTOR;

EID: 84875525848     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2012.11.016     Document Type: Article

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