Effects of new-generation inhibitors of the calcium-activated chloride channel anoctamin 1 on slow waves in the gastrointestinal tract

British Journal of Pharmacology

Volumn 173, Issue 8, 2016, Pages 1339-1349

  Hwang, Sung Jin ^a   Basma, Naseer ^a   Sanders, Kenton M ^a   Ward, Sean M ^a  

^a UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 [(5 ETHYL 1,6 DIHYDRO 4 METHYL 6 OXO 2 PYRIMIDINYL)THIO] N [4 (4 METHOXYPHENYL) 2 THIAZOLYL]ACETAMIDE; 5 NITRO 2 (3 PHENYLPROPYLALANINE)BENZOATE; 6 (1,1 DIMETHYLETHYL) 2 [(2 FURANYLCARBONYL)AMINO] 4,5,6,7 TETRAHYDROBENZO[B]THIOPHENE 3 CARBOXYLIC ACID; ANOCTAMIN 1; BENZBROMARONE; CALCIUM ACTIVATED CHLORIDE CHANNEL; CHLORIDE CHANNEL AFFECTING AGENT; CHLORIDE CHANNEL BLOCKING AGENT; DICHLOROPHEN; HEXACHLOROPHENE; UNCLASSIFIED DRUG; 6-T-BUTYL-2-(FURAN-2-CARBOXAMIDO)-4,5,6,7-TETRAHYDROBENZO(B)THIOPHENE-3-CARBOXYLIC ACID; CHLORIDE CHANNEL; THIOPHENE DERIVATIVE; TMEM16A PROTEIN, MOUSE;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIGESTIVE SYSTEM ELECTROPHYSIOLOGY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG SENSITIVITY; DRUG SPECIFICITY; FEMALE; GASTROINTESTINAL TRACT SLOW WAVE; IC50; INTERSTITIAL CELL OF CAJAL; INTRACELLULAR RECORDING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SMALL INTESTINE MUSCLE; STOMACH ANTRUM; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; GASTROINTESTINAL TRACT; HIGH THROUGHPUT SCREENING; METABOLISM; STRUCTURE ACTIVITY RELATION;

ANIMALS; BENZBROMARONE; CHLORIDE CHANNELS; DICHLOROPHEN; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTROINTESTINAL TRACT; HEXACHLOROPHENE; HIGH-THROUGHPUT SCREENING ASSAYS; MICE; MICE, INBRED C57BL; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

EID: 84959926378     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.13431     Document Type: Article

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