Regional variation in contribution of myenteric and intramuscular interstitial cells of Cajal to generation of slow waves in mouse gastric antrum

Journal of Physiology

Volumn 540, Issue 3, 2002, Pages 1003-1012

  Hirst, G D S ^a   Beckett, E A H ^b   Sanders, K M ^b   Ward, S M ^b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CELL DENSITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ELECTRIC ACTIVITY; FEMALE; INTRACELLULAR RECORDING; MALE; MOUSE; MUSCLE CELL; MYENTERIC PLEXUS; NONHUMAN; OBSERVATION; PACEMAKER; PRIORITY JOURNAL; STOMACH ANTRUM; STOMACH MOTILITY; STOMACH MUSCLE; FOLLOWER CELL; INTERSTITIAL CELL OF CAJAL; INTRAMUSCULAR INTERSTITIAL CELL OF CAJAL; MYENTERIC INTERSTITIAL CELL OF CAJAL; NERVE CELL; PACEMAKER NERVE CELL; SLOW WAVE CELL;

ANIMALS; CONNECTIVE TISSUE; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MUSCLE, SMOOTH; MYENTERIC PLEXUS; ONCOGENE PROTEINS; ONCOGENES; PROTO-ONCOGENE PROTEINS C-KIT; PYLORIC ANTRUM; TIME FACTORS;

EID: 0036588444     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2001.013672     Document Type: Article

References (16)

1. BURNS, A. J., HERBERT, T. M., WARD, S. M. & SANDERS, K. M. (1997). Interstitial cells of Cajal in the guinea-pig gastrointestinal tract as revealed by c-Kit immunohistochemistry. Cell and Tissue Research 290, 11-20.
2. BURNS, A. J., LOMAX, A. E., TORIHASHI, S., SANDERS, K. M. & WARD, S. M. (1996). Interstitial cells of Cajal mediate inhibitory neurotransmission in the stomach. Proceedings of the National Academy of Sciences of the USA 93, 12008-12013.
3. DICKENS, E. J., EDWARDS, F. R. & HIRST, G. D. S. (2001). Selective knockout of intramuscular interstitial cells reveals their role in the generation of slow waves in mouse stomach. Journal of Physiology 531, 827-833.
4. DICKENS, E. I., HIRST, G. D. S. & TOMITA, T. (1999). Identification of rhythmically active cells in guinea-pig stomach. Journal of Physiology 514, 515-531.
5. EDWARDS, F. R., HIRST, G. D. S. & SUZUKI, H. (1999). Unitary nature of regenerative potentials recorded from circular smooth muscle of guinea-pig antrum. Journal of Physiology 519, 235-250.
6. HIRST, G. D. S. & EDWARDS, F. R. (2001). Generation of slow waves in the antral region of guinea-pig stomach - a stochastic process. Journal of Physiology 535, 165-180.
7. HUIZINGA, J. D., THUNEBERG, L., KLUPPEL, M., MALYSZ, J., MIKKELSEN, H. B. & BERNSTEIN, A. (1995). W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature 373, 347-349.
8. ORDOG, T., WARD, S. M. & SANDERS, K. M. (1999). Interstitial cells of Cajal generate electrical slow waves in the murine stomach. Journal of Physiology 518, 257-269.
9. SANDERS, K. M. (1992). Ionic mechanisms of electrical rhythmicity in gastrointestinal smooth muscles. Annual Review of Physiology 54, 439-453.
10. SANDERS, K. M. (1996). A case for interstitial cells of Cajal as pacemakers and mediators of neurotransmission in the gastrointestinal tract. Gastroenterology 111, 492-515.
11. SUZUKI, H. & HIRST, G. D. S. (1999). Regenerative potentials evoked in circular smooth muscle of the antral region of guinea-pig stomach. Journal of Physiology 517, 563-573.
12. TOMITA, T. (1981). Electrical activity (spikes and slow waves) in gastrointestinal smooth muscles. In Smooth Muscle: An Assessment of Current Knowledge, ed. BÜLBRING, E., BRADING, A. F., JONES, A. W. & TOMITA, T., pp. 127-156. Edward Arnold, London.
13. VAN HELDEN, D. F., IMTIAZ, M. S., NURGALIYEVA, K., VON DER WEID, P. & DOSEN, P. J. (2000). Role of calcium stores and membrane voltage in the generation of slow wave action potentials in guinea-pig gastric pylorus. Journal of Physiology 524, 245-265.
14. WARD, S. M., BRENNAN, M. F., JACKSON, V. M. & SANDERS, K. M. (1999). Role of PI3-kinase in the development of interstitial cells and pacemaking in murine gastrointestinal smooth muscle. Journal of Physiology 516, 835-846.
15. WARD, S. M., BURNS, A. J., TORIHASHI, S. & SANDERS, K. M. (1994). Mutation of the proto-oncogene c-kit blocks development of interstitial cells and electrical rhythmicity in murine intestine. Journal of Physiology 480, 91-97.
16. WARD, S. M., HARNEY, S. C., BAYGUINOV, J. R., MCLAREN, G. J. & SANDERS, K. M. (1997). Development of electrical rhythmicity in the murine gastrointestinal tract is specifically encoded in the tunica muscularis. Journal of Physiology 505, 241-258.