A Locus at 5q33.3 Confers Resistance to Tuberculosis in Highly Susceptible Individuals

American Journal of Human Genetics

Volumn 98, Issue 3, 2016, Pages 514-524

  Sobota, Rafal S ^a,b   Stein, Catherine M ^c,d   Kodaman, Nuri ^a,b,c   Scheinfeldt, Laura B ^e,f   Maro, Isaac ^g   Wieland Alter, Wendy ^b   Igo, Robert P ^c   Magohe, Albert ^h   Malone, Lashaunda L ^d   Chervenak, Keith ^d   Hall, Noemi B ^c   Modongo, Chawangwa ^e,i,j   Zetola, Nicola ^e,i,j   Matee, Mecky ^h   Joloba, Moses ^d,k   Froment, Alain ^l   Nyambo, Thomas B ^h   Moore, Jason H ^b,m   Scott, William K ⁿ   Lahey, Timothy ^b   Boom, W Henry ^d   Von Reyn, C Fordham ^b   Tishkoff, Sarah A ^e   Sirugo, Giorgio ^o   Williams, Scott M ^b,c   more..

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d CASE WESTERN RESERVE UNIVERSITY   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f Laboratory of Molecular and Cellular Biology of Hematopoiesis   (United States)

^g TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^h MUHIMBILI UNIVERSITY OF HEALTH AND ALLIED SCIENCES   (Tanzania)

ⁱ BOTSWANA UPENN PARTNERSHIP   (Botswana)

^j UNIVERSITY OF BOTSWANA   (Botswana)

^k MULAGO HOSPITAL   (Uganda)

^l MUSÉE DE L HOMME   (France)

^m UNIVERSITY OF PENNSYLVANIA   (United States)

ⁿ UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^o FATEBENEFRATELLI HOSPITAL   (Italy)

more..

Author keywords

East Africa; histone acetylation; HIV; IL12B; selection; UBLCP1

Indexed keywords

HISTONE; IL12B PROTEIN, HUMAN; INTERLEUKIN 12P40;

ADULT; ARTICLE; CD4 LYMPHOCYTE COUNT; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; GENE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; HAPLOTYPE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; IL12B GENE; INFECTION RESISTANCE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SINGLE NUCLEOTIDE POLYMORPHISM; TANZANIAN; TUBERCULOSIS; UGANDAN; ADOLESCENT; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; METABOLISM; MICROBIOLOGY; MYCOBACTERIUM TUBERCULOSIS; RISK FACTOR; STATISTICAL MODEL; TANZANIA; UGANDA;

ADOLESCENT; FEMALE; GENE FREQUENCY; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HIV INFECTIONS; HUMANS; INTERLEUKIN-12 SUBUNIT P40; LINKAGE DISEQUILIBRIUM; LOGISTIC MODELS; MALE; MYCOBACTERIUM TUBERCULOSIS; PROSPECTIVE STUDIES; RISK FACTORS; TANZANIA; TUBERCULOSIS; UGANDA;

EID: 84959883589     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2016.01.015     Document Type: Article

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