Age-dependent blood pressure elevation is due to increased vascular smooth muscle tone mediated by G-protein signalling

Cardiovascular Research

Volumn 109, Issue 1, 2016, Pages 131-140

  Wirth, Angela ^a,b   Wang, Shengpeng ^a   Takefuji, Mikito ^a   Tang, Cong ^a   Althoff, Till F ^a   Schweda, Frank ^c   Wettschureck, Nina ^a,d   Offermanns, Stefan ^a,d  

^a MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY OF REGENSBURG   (Germany)

^d GOETHE UNIVERSITY   (Germany)

Author keywords

Ageing; Blood pressure; Endothelin; Hypertension; Smooth muscle

Indexed keywords

ENDOTHELIN RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; REACTIVE OXYGEN METABOLITE; TAMOXIFEN; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY ENDOTHELIUM; ARTICLE; BLOOD PRESSURE; BLOOD VESSEL TONE; CONTROLLED STUDY; ELEVATED BLOOD PRESSURE; ENDOTHELIAL DYSFUNCTION; HYPERTENSION; KIDNEY FUNCTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE; ANIMAL; C57BL MOUSE; MOUSE; PHYSIOLOGY; SMOOTH MUSCLE CELL;

AGE FACTORS; ANIMALS; ENDOTHELIN-1; GTP-BINDING PROTEINS; HYPERTENSION; MICE; MICE, INBRED C57BL; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; RECEPTOR, ENDOTHELIN A; SIGNAL TRANSDUCTION;

EID: 84959868876     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvv249     Document Type: Article

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