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Volumn 8, Issue 1, 2003, Pages 107-115

The nitric oxide-endothelin-1 connection

Author keywords

Cardiovascular system; Endothelin; Heart failure; Nitric oxide; Receptor antagonist; Vascular tone

Indexed keywords

3,3 BIS(2 AMINOETHYL) 1 HYDROXY 2 OXOTRIAZENE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BOSENTAN; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); DIETHYLENETRIAMINE NONOATE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENDOTHELIN; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR; ENDOTHELIN B RECEPTOR ANTAGONIST; ENDOTHELIN CONVERTING ENZYME; ENDOTHELIN CONVERTING ENZYME INHIBITOR; ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; LINSIDOMINE; LIVER ENZYME; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRO DERIVATIVE; ORGANIC NITRATE; PLACEBO; SITAXSENTAN; TEZOSENTAN; UNCLASSIFIED DRUG;

EID: 0037233460     PISSN: 13824147     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022155206928     Document Type: Review
Times cited : (104)

References (98)
  • 1
    • 0031054463 scopus 로고    scopus 로고
    • Nitric oxide synthase: Role in the genesis of vascular disease
    • Cooke M, John P, Dzau M, Victor J. Nitric oxide synthase: Role in the genesis of vascular disease. Annu Rev Medicine 1997;48:489-509.
    • (1997) Annu Rev Medicine , vol.48 , pp. 489-509
    • Cooke, M.1    John, P.2    Dzau, M.3    Victor, J.4
  • 2
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
    • Palmer RM, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987;327:524-526.
    • (1987) Nature , vol.327 , pp. 524-526
    • Palmer, R.M.1    Ferrige, A.G.2    Moncada, S.3
  • 3
    • 0023928184 scopus 로고
    • Endothelium-derived relaxing factor. Identification as nitric oxide and role in the control of vascular tone and platelet function
    • Moncada S, Radomski MW, Palmer RM. Endothelium-derived relaxing factor. Identification as nitric oxide and role in the control of vascular tone and platelet function. Biochem Pharmacol 1988;37:2495-2501.
    • (1988) Biochem Pharmacol , vol.37 , pp. 2495-2501
    • Moncada, S.1    Radomski, M.W.2    Palmer, R.M.3
  • 4
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980;288:373-376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 5
    • 0028026868 scopus 로고
    • Nitric oxide synthase: Aspects concerning structure and catalysis
    • Marletta MA. Nitric oxide synthase: Aspects concerning structure and catalysis. Cell 1994;78:927-930.
    • (1994) Cell , vol.78 , pp. 927-930
    • Marletta, M.A.1
  • 8
    • 0025784834 scopus 로고
    • Endogenous nitric oxide: Physiology, pathology and clinical relevance
    • Moncada S, Higgs EA. Endogenous nitric oxide: Physiology, pathology and clinical relevance. Eur J Clin Invest 1991;21:361-374.
    • (1991) Eur J Clin Invest , vol.21 , pp. 361-374
    • Moncada, S.1    Higgs, E.A.2
  • 10
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RM, Higgs EA. Nitric oxide: Physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991;43:109-142.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 11
    • 0025750850 scopus 로고
    • Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells
    • Pollock JS, Forstermann U, Mitchell JA, Warner TD, Schmidt HH, Nakane M, Murad F. Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. Proc Natl Acad Sci USA 1991;88:10480-10484.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 10480-10484
    • Pollock, J.S.1    Forstermann, U.2    Mitchell, J.A.3    Warner, T.D.4    Schmidt, H.H.5    Nakane, M.6    Murad, F.7
  • 12
    • 0023505509 scopus 로고
    • Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
    • Ignarro LJ, Buga GM, Wood KS, Byrns RE, Chaudhuri G. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci USA 1987;84:9265-9269.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 9265-9269
    • Ignarro, L.J.1    Buga, G.M.2    Wood, K.S.3    Byrns, R.E.4    Chaudhuri, G.5
  • 13
    • 0023912670 scopus 로고
    • Vascular endothelial cells synthesize nitric oxide from L-arginine
    • Palmer RM, Ashton DS, Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 1988;333:664-666.
    • (1988) Nature , vol.333 , pp. 664-666
    • Palmer, R.M.1    Ashton, D.S.2    Moncada, S.3
  • 14
    • 0024208276 scopus 로고
    • Macrophage oxidation of L-arginine to nitrite and nitrate: Nitric oxide is an intermediate
    • Marletta MA, Yoon PS, Iyengar R, Leaf CD, Wishnok JS. Macrophage oxidation of L-arginine to nitrite and nitrate: Nitric oxide is an intermediate. Biochem 1988;27:8706-8711.
    • (1988) Biochem , vol.27 , pp. 8706-8711
    • Marletta, M.A.1    Yoon, P.S.2    Iyengar, R.3    Leaf, C.D.4    Wishnok, J.S.5
  • 15
    • 0029444877 scopus 로고
    • Regulation of the expression of the inducible isoform of nitric oxide synthase
    • Szabo C, Thiemermann C. Regulation of the expression of the inducible isoform of nitric oxide synthase. Adv Pharmacol 1995;34:113-153.
    • (1995) Adv Pharmacol , vol.34 , pp. 113-153
    • Szabo, C.1    Thiemermann, C.2
  • 16
    • 0029591748 scopus 로고
    • Nitric oxide-biological mediator, modulator and factor of injury: Its role in the pathogenesis of atherosclerosis
    • Radomski MW, Salas E. Nitric oxide-biological mediator, modulator and factor of injury: Its role in the pathogenesis of atherosclerosis. Atherosclerosis 1995;118 (suppl):S69-S80.
    • (1995) Atherosclerosis , vol.118 , Issue.SUPPL.
    • Radomski, M.W.1    Salas, E.2
  • 17
    • 0025866051 scopus 로고
    • Nitric oxide synthase in cultured endocardial cells of the pig
    • Schulz R, Smith JA, Lewis MJ, Moncada S. Nitric oxide synthase in cultured endocardial cells of the pig. Br J Pharmacol 1991;104:21-24.
    • (1991) Br J Pharmacol , vol.104 , pp. 21-24
    • Schulz, R.1    Smith, J.A.2    Lewis, M.J.3    Moncada, S.4
  • 18
    • 0029057806 scopus 로고
    • Nitric oxide-dependent parasympathetic signaling is due to activation of constitutive endothelial (type III) nitric oxide synthase in cardiac myocytes
    • Balligand JL, Kobzik L, Han X, Kaye DM, Belhassen L, O Hara DS, Kelly RA, Smith TW, Michel T. Nitric oxide-dependent parasympathetic signaling is due to activation of constitutive endothelial (type III) nitric oxide synthase in cardiac myocytes. J Biol Chem 1995;270:14582-14586.
    • (1995) J Biol Chem , vol.270 , pp. 14582-14586
    • Balligand, J.L.1    Kobzik, L.2    Han, X.3    Kaye, D.M.4    Belhassen, L.5    O Hara, D.S.6    Kelly, R.A.7    Smith, T.W.8    Michel, T.9
  • 19
    • 0026542187 scopus 로고
    • Induction and potential biological relevance of a Ca(2+)-independent nitric oxide synthase in the myocardium
    • Schulz R, Nava E, Moncada S. Induction and potential biological relevance of a Ca(2+)-independent nitric oxide synthase in the myocardium. Br J Pharmacol 1992;105:575-580.
    • (1992) Br J Pharmacol , vol.105 , pp. 575-580
    • Schulz, R.1    Nava, E.2    Moncada, S.3
  • 20
    • 0028135094 scopus 로고
    • Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. Characterization and regulation of iNOS expression and detection of iNOS activity in single cardiac myocytes in vitro
    • Balligand JL, Ungureanu-Longrois D, Simmons WW, Pimental D, Malinski TA, Kapturczak M, Taha Z, Lowenstein CJ, Davidoff AJ, Kelly RA. Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. Characterization and regulation of iNOS expression and detection of iNOS activity in single cardiac myocytes in vitro. J Biol Chem 1994;269:27580-27588.
    • (1994) J Biol Chem , vol.269 , pp. 27580-27588
    • Balligand, J.L.1    Ungureanu-Longrois, D.2    Simmons, W.W.3    Pimental, D.4    Malinski, T.A.5    Kapturczak, M.6    Taha, Z.7    Lowenstein, C.J.8    Davidoff, A.J.9    Kelly, R.A.10
  • 21
    • 0025724919 scopus 로고
    • Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator
    • Cooke JP, Rossitch E, Andon NA, Loscalzo J, Dzau VJ. Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator. J Clin Invest 1991;88:1663-1671.
    • (1991) J Clin Invest , vol.88 , pp. 1663-1671
    • Cooke, J.P.1    Rossitch, E.2    Andon, N.A.3    Loscalzo, J.4    Dzau, V.J.5
  • 22
    • 0023187143 scopus 로고
    • Comparative pharmacology of endothelium-derived relaxing factor, nitric oxide and prostacyclin in platelets
    • Radomski MW, Palmer RM, Moncada S. Comparative pharmacology of endothelium-derived relaxing factor, nitric oxide and prostacyclin in platelets. Br J Pharmacol 1987;92:181-187.
    • (1987) Br J Pharmacol , vol.92 , pp. 181-187
    • Radomski, M.W.1    Palmer, R.M.2    Moncada, S.3
  • 23
    • 0023200487 scopus 로고
    • Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium
    • Radomski MW, Palmer RM, Moncada S. Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium. Lancet 1987;2:1057-1058.
    • (1987) Lancet , vol.2 , pp. 1057-1058
    • Radomski, M.W.1    Palmer, R.M.2    Moncada, S.3
  • 24
    • 0023568115 scopus 로고
    • The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium
    • Radomski MW, Palmer RM, Moncada S. The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium. Biochem Biophys Res Commun 1987;148:1482-1489.
    • (1987) Biochem Biophys Res Commun , vol.148 , pp. 1482-1489
    • Radomski, M.W.1    Palmer, R.M.2    Moncada, S.3
  • 25
    • 0023446425 scopus 로고
    • The anti-aggregating properties of vascular endothelium: Interactions between prostacyclin and nitric oxide
    • Radomski MW, Palmer RM, Moncada S. The anti-aggregating properties of vascular endothelium: Interactions between prostacyclin and nitric oxide. Br J Pharmacol 1987;92:639-646.
    • (1987) Br J Pharmacol , vol.92 , pp. 639-646
    • Radomski, M.W.1    Palmer, R.M.2    Moncada, S.3
  • 26
    • 0033646549 scopus 로고    scopus 로고
    • Vascular effects of endothelin-1 in essential hypertension: Relationship with cyclooxygenase-derived endothelium-dependent contracting factors and nitric oxide
    • Taddei S, Virdis A, Ghiadoni L, Salvetti A. Vascular effects of endothelin-1 in essential hypertension: Relationship with cyclooxygenase-derived endothelium-dependent contracting factors and nitric oxide. J Cardiovasc Pharmacol 2000;35(4):S37-S40.
    • (2000) J Cardiovasc Pharmacol , vol.35 , Issue.4
    • Taddei, S.1    Virdis, A.2    Ghiadoni, L.3    Salvetti, A.4
  • 27
    • 0033061853 scopus 로고    scopus 로고
    • Regulation of basal myocardial function by NO
    • Kojda G, Kottenberg K. Regulation of basal myocardial function by NO. Cardiovasc Res 1999;41:514-523.
    • (1999) Cardiovasc Res , vol.41 , pp. 514-523
    • Kojda, G.1    Kottenberg, K.2
  • 28
    • 0022067275 scopus 로고
    • Characterization of a coronary vasoconstrictor produced by cultured endothelial cells
    • Hickey KA, Rubanyi G, Paul RJ, Highsmith RF. Characterization of a coronary vasoconstrictor produced by cultured endothelial cells. Am J Physiol 1985;248:C550-C556.
    • (1985) Am J Physiol , vol.248
    • Hickey, K.A.1    Rubanyi, G.2    Paul, R.J.3    Highsmith, R.F.4
  • 29
    • 0023626734 scopus 로고
    • Endothelial cells in culture produce a vasoconstrictor substance
    • O'Brien RF, Robbins RJ, McMurtry IF. Endothelial cells in culture produce a vasoconstrictor substance. J Cell Physiol 1987;132:263-270.
    • (1987) J Cell Physiol , vol.132 , pp. 263-270
    • O'Brien, R.F.1    Robbins, R.J.2    McMurtry, I.F.3
  • 31
    • 0035040924 scopus 로고    scopus 로고
    • Endothelin system: The double-edged sword in health and disease
    • Kedzierski RM, Yanagisawa M. Endothelin system: The double-edged sword in health and disease. Annu Rev Pharmacol Toxicol 2001;41:851-876.
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 851-876
    • Kedzierski, R.M.1    Yanagisawa, M.2
  • 32
    • 0013543367 scopus 로고
    • The human endothelin family: Three structurally and pharmacologically distinct isopeptides predicted by three separate genes
    • Inoue A, Yanagisawa M, Kimura S, Kasuya Y, Miyauchi T, Goto K, Masaki T. The human endothelin family: Three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc Natl Acad Sci USA 1989;86:2863-2867.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2863-2867
    • Inoue, A.1    Yanagisawa, M.2    Kimura, S.3    Kasuya, Y.4    Miyauchi, T.5    Goto, K.6    Masaki, T.7
  • 34
    • 0024521522 scopus 로고
    • Conversion of big endothelin-1 to 21-residue endothelin-1 is essential for expression of full vasoconstrictor activity: Structure-activity relationships of big endothelin-1
    • discussion S18
    • Kimura S, Kasuya Y, Sawamura T, Shinimi O, Sugita Y, Yanagisawa M, Goto K, Masaki T. Conversion of big endothelin-1 to 21-residue endothelin-1 is essential for expression of full vasoconstrictor activity: Structure-activity relationships of big endothelin-1. J Cardiovasc Pharmacol 1989;13 (suppl. 5):S5-S7; discussion S18.
    • (1989) J Cardiovasc Pharmacol , vol.13 , Issue.SUPPL. 5
    • Kimura, S.1    Kasuya, Y.2    Sawamura, T.3    Shinimi, O.4    Sugita, Y.5    Yanagisawa, M.6    Goto, K.7    Masaki, T.8
  • 35
    • 0025072065 scopus 로고
    • Phosphoramidon, a metalloproteinase inhibitor, suppresses the hypertensive effect of big endothelin-1
    • Matsumura Y, Hisaki K, Takaoka M, Morimoto S. Phosphoramidon, a metalloproteinase inhibitor, suppresses the hypertensive effect of big endothelin-1. Eur J Pharmacol 1990;185:103-106.
    • (1990) Eur J Pharmacol , vol.185 , pp. 103-106
    • Matsumura, Y.1    Hisaki, K.2    Takaoka, M.3    Morimoto, S.4
  • 36
    • 0028261084 scopus 로고
    • Cloning and functional expression of endothelin-converting enzyme from rat endothelial cells
    • Shimada K, Takahashi M, Tanzawa K. Cloning and functional expression of endothelin-converting enzyme from rat endothelial cells. J Biol Chem 1994;269:18275-18278.
    • (1994) J Biol Chem , vol.269 , pp. 18275-18278
    • Shimada, K.1    Takahashi, M.2    Tanzawa, K.3
  • 37
    • 0027992642 scopus 로고
    • ECE-1: A membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1
    • Xu D, Emoto N, Giaid A, Slaughter C, Kaw S, DeWit D, Yanagisawa M. ECE-1: A membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1. Cell 1994;78:473-485.
    • (1994) Cell , vol.78 , pp. 473-485
    • Xu, D.1    Emoto, N.2    Giaid, A.3    Slaughter, C.4    Kaw, S.5    Dewit, D.6    Yanagisawa, M.7
  • 38
    • 0029017876 scopus 로고
    • Endothelin-converting enzyme-2 is a membrane-bound, phosphoramidon-sensitive metalloprotease with acidic pH optimum
    • Emoto N, Yanagisawa M. Endothelin-converting enzyme-2 is a membrane-bound, phosphoramidon-sensitive metalloprotease with acidic pH optimum. J Biol Chem 1995;270:15262-15268.
    • (1995) J Biol Chem , vol.270 , pp. 15262-15268
    • Emoto, N.1    Yanagisawa, M.2
  • 39
    • 0032932090 scopus 로고    scopus 로고
    • Cellular distribution of endothelin-converting enzyme-1 in human tissues
    • Korth P, Bohle RM, Corvol P, Pinet F. Cellular distribution of endothelin-converting enzyme-1 in human tissues. J Histochem Cytochem 1999;47:447-462.
    • (1999) J Histochem Cytochem , vol.47 , pp. 447-462
    • Korth, P.1    Bohle, R.M.2    Corvol, P.3    Pinet, F.4
  • 41
    • 0033198791 scopus 로고    scopus 로고
    • A fourth isoform of endothelin-converting enzyme (ECE-1) is generated from an additional promoter: Molecular cloning and characterization
    • Valdenaire O, Lepailleur-Enouf D, Egidy G, Thouard A, Barret A, Vranckx R, Tougard C, Michel J-B. A fourth isoform of endothelin-converting enzyme (ECE-1) is generated from an additional promoter: Molecular cloning and characterization. Eur J Biochem 1999;264:341-349.
    • (1999) Eur J Biochem , vol.264 , pp. 341-349
    • Valdenaire, O.1    Lepailleur-Enouf, D.2    Egidy, G.3    Thouard, A.4    Barret, A.5    Vranckx, R.6    Tougard, C.7    Michel, J.-B.8
  • 42
    • 0032719798 scopus 로고    scopus 로고
    • Vascular matrix metalloproteinase-2 cleaves big endothelin-1 yielding a novel vasoconstrictor
    • Fernandez-Patron C, Radomski MW, Davidge ST. Vascular matrix metalloproteinase-2 cleaves big endothelin-1 yielding a novel vasoconstrictor. Circ Res 1999;85:906-911.
    • (1999) Circ Res , vol.85 , pp. 906-911
    • Fernandez-Patron, C.1    Radomski, M.W.2    Davidge, S.T.3
  • 43
    • 0034806212 scopus 로고    scopus 로고
    • Matrix metalloproteinases regulate neutrophil-endothelial cell adhesion through generation of endothelin-1 [1-32]
    • Fernandez-Patron C, Zouki C, Whittal R, Chan JS, Davidge ST, Filep JG. Matrix metalloproteinases regulate neutrophil-endothelial cell adhesion through generation of endothelin-1 [1-32]. FASEB J 2001;15:2230-2240.
    • (2001) FASEB J , vol.15 , pp. 2230-2240
    • Fernandez-Patron, C.1    Zouki, C.2    Whittal, R.3    Chan, J.S.4    Davidge, S.T.5    Filep, J.G.6
  • 44
    • 0024427985 scopus 로고
    • The human preproendothelin-1 gene. Complete nucleotide sequence and regulation of expression
    • Inoue A, Yanagisawa M, Takuwa Y, Mitsui Y, Kobayashi M, Masaki T. The human preproendothelin-1 gene. Complete nucleotide sequence and regulation of expression. J Biol Chem 1989;264:14954-14959.
    • (1989) J Biol Chem , vol.264 , pp. 14954-14959
    • Inoue, A.1    Yanagisawa, M.2    Takuwa, Y.3    Mitsui, Y.4    Kobayashi, M.5    Masaki, T.6
  • 45
    • 0025372848 scopus 로고
    • Functional analysis of the endothelin-1 gene promoter. Evidence for an endothelial cell-specific cis-acting sequence
    • Lee ME, Bloch KD, Clifford JA, Quertermous T. Functional analysis of the endothelin-1 gene promoter. Evidence for an endothelial cell-specific cis-acting sequence. The Journal of Biological Chemistry 1990;265:10446-10450.
    • (1990) The Journal of Biological Chemistry , vol.265 , pp. 10446-10450
    • Lee, M.E.1    Bloch, K.D.2    Clifford, J.A.3    Quertermous, T.4
  • 46
    • 0029006385 scopus 로고
    • Cooperative interaction of GATA-2 and AP1 regulates transcription of the endothelin-1 gene
    • Kawana M, Lee ME, Quertermous EE, Quertermous T. Cooperative interaction of GATA-2 and AP1 regulates transcription of the endothelin-1 gene. Mol Cell Biol 1995;15:4225-4231.
    • (1995) Mol Cell Biol , vol.15 , pp. 4225-4231
    • Kawana, M.1    Lee, M.E.2    Quertermous, E.E.3    Quertermous, T.4
  • 47
    • 0025605345 scopus 로고
    • Cloning and expression of a cDNA encoding an endothelin receptor
    • Arai H, Hori S, Aramori I, Ohkubo H, Nakanishi S. Cloning and expression of a cDNA encoding an endothelin receptor. Nature 1990;348:730-732.
    • (1990) Nature , vol.348 , pp. 730-732
    • Arai, H.1    Hori, S.2    Aramori, I.3    Ohkubo, H.4    Nakanishi, S.5
  • 48
    • 0025605930 scopus 로고
    • Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor
    • Sakurai T, Yanagisawa M, Takuwa Y, Miyazaki H, Kimura S, Goto K, Masaki T. Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature 1990;348:732-735.
    • (1990) Nature , vol.348 , pp. 732-735
    • Sakurai, T.1    Yanagisawa, M.2    Takuwa, Y.3    Miyazaki, H.4    Kimura, S.5    Goto, K.6    Masaki, T.7
  • 49
    • 0025265191 scopus 로고
    • Endothelin receptor is coupled to phospholipase C via a pertussis toxin-insensitive guanine nucleotide-binding regulatory protein in vascular smooth muscle cells
    • Takuwa Y, Kasuya Y, Takuwa N, Kudo M, Yanagisawa M, Goto K, Masaki T, Yamashita K. Endothelin receptor is coupled to phospholipase C via a pertussis toxin-insensitive guanine nucleotide-binding regulatory protein in vascular smooth muscle cells. J Clin Invest 1990;85:653-658.
    • (1990) J Clin Invest , vol.85 , pp. 653-658
    • Takuwa, Y.1    Kasuya, Y.2    Takuwa, N.3    Kudo, M.4    Yanagisawa, M.5    Goto, K.6    Masaki, T.7    Yamashita, K.8
  • 50
    • 0024363298 scopus 로고
    • Endothelin stimulates diacylglycerol accumulation and activates protein kinase C in cultured vascular smooth muscle cells
    • Griendling KK, Tsuda T, Alexander RW. Endothelin stimulates diacylglycerol accumulation and activates protein kinase C in cultured vascular smooth muscle cells. J Biol Chem 1989;264:8237-8240.
    • (1989) J Biol Chem , vol.264 , pp. 8237-8240
    • Griendling, K.K.1    Tsuda, T.2    Alexander, R.W.3
  • 51
    • 0025221768 scopus 로고
    • Cellular signaling by peptides of the endothelin gene family
    • Simonson MS, Dunn MJ. Cellular signaling by peptides of the endothelin gene family. FASEB J 1990;4:2989-3000.
    • (1990) FASEB J , vol.4 , pp. 2989-3000
    • Simonson, M.S.1    Dunn, M.J.2
  • 52
    • 0031829004 scopus 로고    scopus 로고
    • Endothelin as a regulator of cardiovascular function in health and disease
    • Haynes WG, Webb DJ. Endothelin as a regulator of cardiovascular function in health and disease. J Hypertens 1998;16:1081-1098.
    • (1998) J Hypertens , vol.16 , pp. 1081-1098
    • Haynes, W.G.1    Webb, D.J.2
  • 53
    • 0027983753 scopus 로고
    • Contribution of endogenous generation of endothelin-1 to basal vascular tone
    • Haynes WG, Webb DJ. Contribution of endogenous generation of endothelin-1 to basal vascular tone. Lancet 1994;344:852-854.
    • (1994) Lancet , vol.344 , pp. 852-854
    • Haynes, W.G.1    Webb, D.J.2
  • 54
    • 0029886596 scopus 로고    scopus 로고
    • Systemic endothelin receptor blockade decreases peripheral vascular resistance and blood pressure in humans
    • Haynes WG, Ferro CJ, O Kane KP, Somerville D, Lomax CC, Webb DJ. Systemic endothelin receptor blockade decreases peripheral vascular resistance and blood pressure in humans. Circulation 1996;93:1860-1870.
    • (1996) Circulation , vol.93 , pp. 1860-1870
    • Haynes, W.G.1    Ferro, C.J.2    O Kane, K.P.3    Somerville, D.4    Lomax, C.C.5    Webb, D.J.6
  • 55
    • 0032959132 scopus 로고    scopus 로고
    • Endothelin-1 is induced by cytokines in human vascular smooth muscle cells: Evidence for intracellular endothelin-converting enzyme
    • Woods M, Mitchell JA, Wood EG, Barker S, Walcot NR, Rees GM, Warner TD. Endothelin-1 is induced by cytokines in human vascular smooth muscle cells: Evidence for intracellular endothelin-converting enzyme. Molecular Pharmacology 1999;55:902-909.
    • (1999) Molecular Pharmacology , vol.55 , pp. 902-909
    • Woods, M.1    Mitchell, J.A.2    Wood, E.G.3    Barker, S.4    Walcot, N.R.5    Rees, G.M.6    Warner, T.D.7
  • 57
    • 0023805236 scopus 로고
    • Regional vasodilation is a prominent feature of the haemodynamic response to endothelin in anaesthetized, spontaneously hypertensive rats
    • Wright CE, Fozard JR. Regional vasodilation is a prominent feature of the haemodynamic response to endothelin in anaesthetized, spontaneously hypertensive rats. Eur J Pharmacol 1988;155:201-203.
    • (1988) Eur J Pharmacol , vol.155 , pp. 201-203
    • Wright, C.E.1    Fozard, J.R.2
  • 58
    • 0004559340 scopus 로고
    • Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor
    • De Nucci G, Thomas R, D Orleans-Juste P, Antunes E, Walder C, Warner TD, Vane JR. Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor. Proc Natl Acad Sci USA 1988;85:9797-9800.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 9797-9800
    • De Nucci, G.1    Thomas, R.2    D Orleans-Juste, P.3    Antunes, E.4    Walder, C.5    Warner, T.D.6    Vane, J.R.7
  • 59
    • 0028981194 scopus 로고
    • Endothelin ETA and ETB receptors cause vasoconstriction of human resistance and capacitance vessels in vivo
    • Haynes WG, Strachan FE, Webb DJ. Endothelin ETA and ETB receptors cause vasoconstriction of human resistance and capacitance vessels in vivo. Circulation 1995;92:357-363.
    • (1995) Circulation , vol.92 , pp. 357-363
    • Haynes, W.G.1    Strachan, F.E.2    Webb, D.J.3
  • 60
    • 0033068028 scopus 로고    scopus 로고
    • Pathophysiology of endothelin in the cardiovascular system
    • Miyauchi T, Masaki T. Pathophysiology of endothelin in the cardiovascular system. Annu Rev Physiol 1999;61:391-415.
    • (1999) Annu Rev Physiol , vol.61 , pp. 391-415
    • Miyauchi, T.1    Masaki, T.2
  • 61
    • 0034124224 scopus 로고    scopus 로고
    • Interactions between nitric oxide and endothelin in the regulation of vascular tone of human resistance vessels in vivo
    • Cardillo C, Kilcoyne CM, Cannon RO, Panza JA. Interactions between nitric oxide and endothelin in the regulation of vascular tone of human resistance vessels in vivo. Hypertension 2000;35:1237-1241.
    • (2000) Hypertension , vol.35 , pp. 1237-1241
    • Cardillo, C.1    Kilcoyne, C.M.2    Cannon, R.O.3    Panza, J.A.4
  • 66
    • 0027233868 scopus 로고
    • Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life
    • Yoshizumi M, Perella MA, Burnett JC, Lee ME. Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life. Circ Res 1993;73:205-209.
    • (1993) Circ Res , vol.73 , pp. 205-209
    • Yoshizumi, M.1    Perella, M.A.2    Burnett, J.C.3    Lee, M.E.4
  • 70
    • 0026634049 scopus 로고
    • Increased plasma concentrations of endothelin in congestive heart failure in humans
    • Rodeheffer RJ, Lerman A, Heublein DM, Burnett JC. Increased plasma concentrations of endothelin in congestive heart failure in humans. Mayo Clin Proc 1992;67:719-724.
    • (1992) Mayo Clin Proc , vol.67 , pp. 719-724
    • Rodeheffer, R.J.1    Lerman, A.2    Heublein, D.M.3    Burnett, J.C.4
  • 75
    • 0026045505 scopus 로고
    • Effects of endothelin-1 on endothelial cells in the porcine coronary artery
    • Suzuki S, Kajikuri J, Suzuki A, Itoh T. Effects of endothelin-1 on endothelial cells in the porcine coronary artery. Circ Res 1991;69:1361-1368.
    • (1991) Circ Res , vol.69 , pp. 1361-1368
    • Suzuki, S.1    Kajikuri, J.2    Suzuki, A.3    Itoh, T.4
  • 76
    • 0032478272 scopus 로고    scopus 로고
    • Endothelin-A receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade
    • Verhaar MC, Strachan FE, Newby DE, Cruden NL, Koomans HA, Rabelink TJ, Webb DJ. Endothelin-A receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade. Circulation 1998;97:752-756.
    • (1998) Circulation , vol.97 , pp. 752-756
    • Verhaar, M.C.1    Strachan, F.E.2    Newby, D.E.3    Cruden, N.L.4    Koomans, H.A.5    Rabelink, T.J.6    Webb, D.J.7
  • 77
    • 0026602536 scopus 로고
    • Inhibition of endothelium-derived relaxing factor enhances endothelin-mediated vasoconstriction
    • Lerman A, Sandok EK, Hildebrand FL, Burnett JC. Inhibition of endothelium-derived relaxing factor enhances endothelin-mediated vasoconstriction. Circulation 1992;85:1894-1898.
    • (1992) Circulation , vol.85 , pp. 1894-1898
    • Lerman, A.1    Sandok, E.K.2    Hildebrand, F.L.3    Burnett, J.C.4
  • 78
    • 0031010719 scopus 로고    scopus 로고
    • Nitric oxide-endothelin-1 interaction in humans
    • Ahlborg G, Lundberg JM. Nitric oxide-endothelin-1 interaction in humans. J Appl Physiol 1997;82:1593-1600.
    • (1997) J Appl Physiol , vol.82 , pp. 1593-1600
    • Ahlborg, G.1    Lundberg, J.M.2
  • 79
    • 0029792208 scopus 로고    scopus 로고
    • Acute hypertension after nitric oxide synthase inhibition is mediated primarily by increased endothelin vasoconstriction
    • Banting JD, Friberg P, Adams MA. Acute hypertension after nitric oxide synthase inhibition is mediated primarily by increased endothelin vasoconstriction. J Hypertens 1996;14:975-981.
    • (1996) J Hypertens , vol.14 , pp. 975-981
    • Banting, J.D.1    Friberg, P.2    Adams, M.A.3
  • 80
    • 0025100874 scopus 로고
    • Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide
    • Boulanger C, Luscher TF. Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide. J Clin Invest 1990;85:587-590.
    • (1990) J Clin Invest , vol.85 , pp. 587-590
    • Boulanger, C.1    Luscher, T.F.2
  • 81
    • 0026680586 scopus 로고
    • Interactions of endothelins and EDRF in bovine native endothelial cells: Selective effects of endothelin-3
    • Warner TD, Schmidt HH, Murad F. Interactions of endothelins and EDRF in bovine native endothelial cells: Selective effects of endothelin-3. Am J Physiol 1992;262:H1600-H1605.
    • (1992) Am J Physiol , vol.262
    • Warner, T.D.1    Schmidt, H.H.2    Murad, F.3
  • 82
    • 0030444643 scopus 로고    scopus 로고
    • The endothelin system and its potential as a therapeutic target in cardiovascular disease
    • Gray GA, Webb DJ. The endothelin system and its potential as a therapeutic target in cardiovascular disease. Pharmacol Ther 1996;72:109-148.
    • (1996) Pharmacol Ther , vol.72 , pp. 109-148
    • Gray, G.A.1    Webb, D.J.2
  • 83
    • 0029918681 scopus 로고    scopus 로고
    • Regulation of endothelin receptors by nitric oxide in cultured rat vascular smooth muscle cells
    • Redmond EM, Cahill PA, Hodges R, Zhang S, Sitzmann JV. Regulation of endothelin receptors by nitric oxide in cultured rat vascular smooth muscle cells. J Cell Physiol 1996;166:469-479.
    • (1996) J Cell Physiol , vol.166 , pp. 469-479
    • Redmond, E.M.1    Cahill, P.A.2    Hodges, R.3    Zhang, S.4    Sitzmann, J.V.5
  • 85
    • 0033735048 scopus 로고    scopus 로고
    • Effect of a highly selective endothelin-converting enzyme inhibitor on cardiac remodeling in rats after myocardial infarction
    • Martin P, Tzanidis A, Stein Oakley A, Krum H. Effect of a highly selective endothelin-converting enzyme inhibitor on cardiac remodeling in rats after myocardial infarction. J Cardiovasc Pharmacol 2000;36:S367-S370.
    • (2000) J Cardiovasc Pharmacol , vol.36
    • Martin, P.1    Tzanidis, A.2    Stein Oakley, A.3    Krum, H.4
  • 86
    • 0033755603 scopus 로고    scopus 로고
    • Pharmacological properties of CGS 35066, a potent and selective endothelin-converting enzyme inhibitor, in conscious rats
    • Trapani AJ, Beil ME, Bruseo CW, De Lombaert S, Jeng AY. Pharmacological properties of CGS 35066, a potent and selective endothelin-converting enzyme inhibitor, in conscious rats. J Cardiovasc Pharmacol 2000;36:S40-S43.
    • (2000) J Cardiovasc Pharmacol , vol.36
    • Trapani, A.J.1    Beil, M.E.2    Bruseo, C.W.3    De Lombaert, S.4    Jeng, A.Y.5
  • 87
    • 0032564374 scopus 로고    scopus 로고
    • Short-term oral endothelin-receptor antagonist therapy in conventionally treated patients with symptomatic severe chronic heart failure
    • Sutsch G, Kiowski W, Yan XW, Hunziker P, Christen S, Strobel W, Kim JH, Rickenbacher P, Bertel O. Short-term oral endothelin-receptor antagonist therapy in conventionally treated patients with symptomatic severe chronic heart failure. Circulation 1998;98:2262-2268.
    • (1998) Circulation , vol.98 , pp. 2262-2268
    • Sutsch, G.1    Kiowski, W.2    Yan, X.W.3    Hunziker, P.4    Christen, S.5    Strobel, W.6    Kim, J.H.7    Rickenbacher, P.8    Bertel, O.9
  • 88
    • 0002132147 scopus 로고    scopus 로고
    • Multicenter, double-blind, placebo-controlled study of long-term endothelin blockade with bosentan in chronic heart failure - Results of the REACH-1 trial
    • Packer M, Caspi A, Charlon V, La Roche H, Cohen-Solal A, Kiowski W. Multicenter, double-blind, placebo-controlled study of long-term endothelin blockade with bosentan in chronic heart failure - Results of the REACH-1 trial. Circulation 1998;98 (suppl.):1-3.
    • (1998) Circulation , vol.98 , Issue.SUPPL. , pp. 1-3
    • Packer, M.1    Caspi, A.2    Charlon, V.3    La Roche, H.4    Cohen-Solal, A.5    Kiowski, W.6
  • 89
    • 0036073071 scopus 로고    scopus 로고
    • Endothelin antagonism with bosentan: Current status and future perspectives
    • Ono K, Matsumori A. Endothelin antagonism with bosentan: Current status and future perspectives. Cardiovasc Drug Rev 2002;20:1-18.
    • (2002) Cardiovasc Drug Rev , vol.20 , pp. 1-18
    • Ono, K.1    Matsumori, A.2
  • 90
    • 0034895218 scopus 로고    scopus 로고
    • The dual endothelin receptor antagonist tezosentan acutely improves hemodynamic parameters in patients with advanced heart failure
    • Schalcher C, Cotter G, Reisin L, Bertel O, Kobrin I, Guyene TT, Kiowski W. The dual endothelin receptor antagonist tezosentan acutely improves hemodynamic parameters in patients with advanced heart failure. Am Heart J 2001;142:340-349.
    • (2001) Am Heart J , vol.142 , pp. 340-349
    • Schalcher, C.1    Cotter, G.2    Reisin, L.3    Bertel, O.4    Kobrin, I.5    Guyene, T.T.6    Kiowski, W.7
  • 91
    • 0034825957 scopus 로고    scopus 로고
    • A pilot safety trial of prolonged (48 h) infusion of the dual endothelin-receptor antagonist tezosentan in patients with advanced heart failure
    • Torre Amione G, Durand JB, Nagueh S, Vooletich MT, Kobrin I, Pratt C. A pilot safety trial of prolonged (48 h) infusion of the dual endothelin-receptor antagonist tezosentan in patients with advanced heart failure. Chest 2001;120:460-466.
    • (2001) Chest , vol.120 , pp. 460-466
    • Torre Amione, G.1    Durand, J.B.2    Nagueh, S.3    Vooletich, M.T.4    Kobrin, I.5    Pratt, C.6
  • 92
    • 0032543936 scopus 로고    scopus 로고
    • Short-term haemodynamic effects of BQ-123, a selective endothelin ET(A)-receptor antagonist, in chronic heart failure
    • Cowburn PJ, Cleland JG, McArthur JD, MacLean MR, McMurray JJ, Dargie HJ. Short-term haemodynamic effects of BQ-123, a selective endothelin ET(A)-receptor antagonist, in chronic heart failure. Lancet 1998;352:201-202.
    • (1998) Lancet , vol.352 , pp. 201-202
    • Cowburn, P.J.1    Cleland, J.G.2    McArthur, J.D.3    MacLean, M.R.4    McMurray, J.J.5    Dargie, H.J.6
  • 93
    • 0033844908 scopus 로고    scopus 로고
    • Cardioprotection from ischemia and reperfusion injury by an endothelin A-receptor antagonist in relation to nitric oxide production
    • Gonon AT, Gourine AV, Pernow J. Cardioprotection from ischemia and reperfusion injury by an endothelin A-receptor antagonist in relation to nitric oxide production. J Cardiovasc Pharmacol 2000;36:405-412.
    • (2000) J Cardiovasc Pharmacol , vol.36 , pp. 405-412
    • Gonon, A.T.1    Gourine, A.V.2    Pernow, J.3
  • 96
    • 0033756009 scopus 로고    scopus 로고
    • Novel nitric oxide donors reverse endothelin-1-mediated constriction in human blood vessels
    • Wiley KE, Davenport AP. Novel nitric oxide donors reverse endothelin-1-mediated constriction in human blood vessels. J Cardiovasc Pharmacol 2000;36:S151-S152.
    • (2000) J Cardiovasc Pharmacol , vol.36
    • Wiley, K.E.1    Davenport, A.P.2
  • 97
    • 0347186957 scopus 로고    scopus 로고
    • Nitric oxide, platelet function, myocardial infarction and reperfusion therapies
    • Alonso D, Radomski MW. Nitric oxide, platelet function, myocardial infarction and reperfusion therapies. Heart Fail Rev 2002.
    • (2002) Heart Fail Rev
    • Alonso, D.1    Radomski, M.W.2
  • 98
    • 0035846616 scopus 로고    scopus 로고
    • ACC/AHA Guidelines for the Evaluation and Management of Chronic Heart Failure in the Adult: Executive summary
    • A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1995 Guidelines for the Evaluation and Management of Heart Failure): Developed in Collaboration with the International Society for Heart and Lung Transplantation; endorsed by the Heart Failure Society of America; endorsed by the Heart Failure Society of America
    • Hunt SA, Baker DW, Chin MH, Cinquegrani MP, Feldmanmd AM, Francis GS, Ganiats TG, Goldstein S, Gregoratos G, Jessup ML, Noble RJ, Packer M, Silver MA, Stevenson LW, Gibbons RJ, Antman EM, Alpert JS, Faxon DP, Fuster V, Jacobs AK, Hiratzka LF, Russell RO, Smith SC, and ACC/AHA Guidelines for the Evaluation and Management of Chronic Heart Failure in the Adult: Executive summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1995 Guidelines for the Evaluation and Management of Heart Failure): Developed in Collaboration with the International Society for Heart and Lung Transplantation; endorsed by the Heart Failure Society of America; endorsed by the Heart Failure Society of America. Circulation 2001;104:2996-3007.
    • (2001) Circulation , vol.104 , pp. 2996-3007
    • Hunt, S.A.1    Baker, D.W.2    Chin, M.H.3    Cinquegrani, M.P.4    Feldmanmd, A.M.5    Francis, G.S.6    Ganiats, T.G.7    Goldstein, S.8    Gregoratos, G.9    Jessup, M.L.10    Noble, R.J.11    Packer, M.12    Silver, M.A.13    Stevenson, L.W.14    Gibbons, R.J.15    Antman, E.M.16    Alpert, J.S.17    Faxon, D.P.18    Fuster, V.19    Jacobs, A.K.20    more..


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