Apolipoprotein E receptor 2 mediates activated Protein C-induced endothelial Akt activation and endothelial barrier stabilization

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 36, Issue 3, 2016, Pages 518-524

  Sinha, Ranjeet K ^a   Yang, Xia V ^a   Fernández, José A ^a   Xu, Xiao ^a   Mosnier, Laurent O ^a   Griffin, John H ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

apolipoprotein E receptor 2; apoptosis; endothelial cells; low density lipoprotein receptor related protein 8; protein C; signal transduction

Indexed keywords

1 AMINO 3 CYCLOPROPYLAMINO 7 (4 ISOPROPYLBENZYL) 7H PYRROLO[3,2 F]QUINAZOLINE; ACTIVATED PROTEIN C; APOLIPOPROTEIN E; APOLIPOPROTEIN E RECEPTOR 2; ASPARTIC ACID; DISABLED 1 PROTEIN; ENZYME INHIBITOR; LY 303511; LYSINE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; PROTEINASE ACTIVATED RECEPTOR 1; SMALL INTERFERING RNA; THROMBIN; TRYPTOPHAN; UNCLASSIFIED DRUG; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 8; NERVE CELL ADHESION MOLECULE; NERVE PROTEIN; PROTEIN C; PROTEIN KINASE INHIBITOR; REELIN PROTEIN; SCLEROPROTEIN; SERINE PROTEINASE;

APOPTOSIS; ARTICLE; BINDING SITE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANTAGONISTS AND INHIBITORS; CELL LINE; CELL MEMBRANE PERMEABILITY; DRUG EFFECTS; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; IMPEDANCE; METABOLISM; PHOSPHORYLATION; RNA INTERFERENCE; TIME FACTOR;

APOPTOSIS; CELL ADHESION MOLECULES, NEURONAL; CELL LINE; CELL MEMBRANE PERMEABILITY; ELECTRIC IMPEDANCE; ENDOTHELIAL CELLS; ENZYME ACTIVATION; EXTRACELLULAR MATRIX PROTEINS; HUMANS; LDL-RECEPTOR RELATED PROTEINS; NERVE TISSUE PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN C; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, PAR-1; RNA INTERFERENCE; SERINE ENDOPEPTIDASES; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TIME FACTORS; TRANSFECTION;

EID: 84959573772     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.115.306795     Document Type: Article

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