Endothelial Cell Bioenergetics and Mitochondrial DNA Damage Differ in Humans Having African or West Eurasian Maternal Ancestry

Circulation: Cardiovascular Genetics

Volumn 9, Issue 1, 2016, Pages 26-36

  Krzywanski, David M ^a   Moellering, Douglas R ^b,c   Westbrook, David G ^c,d   Dunham Snary, Kimberly J ^c,f   Brown, Jamelle ^c,d   Bray, Alexander W ^c,d   Feeley, Kyle P ^c,d   Sammy, Melissa J ^c,d   Smith, Matthew R ^c,d   Schurr, Theodore G ^g   Vita, Joseph A ^h   Ambalavanan, Namasivayam ^b   Calhoun, David ^e   Dell'Italia, Louis ^c,e   Ballinger, Scott W ^c,d  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b Department of Nutrition Sciences ^*  (United States)

^c Center for Free Radical Biology and Medicine   (United States)

^d University of Alabama at Birmingham   (United States)

^e UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

^f QUEEN S UNIVERSITY   (Canada)

^g UNIVERSITY OF PENNSYLVANIA   (United States)

^h BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

coronary artery disease; DNA, mitochondrial; endothelial cells; genetics; human umbilical vein endothelial cell; mitochondria

Indexed keywords

ADENOSINE TRIPHOSPHATE; MITOCHONDRIAL DNA; NUCLEOTIDE; OXYGEN;

AFRICAN AMERICAN; ANCESTRY GROUP; ANGIOGRAPHY; ARTICLE; BIOENERGY; CORONARY ARTERY DISEASE; DNA DAMAGE; ENDOTHELIUM CELL; EUROPEAN AMERICAN; FEMALE; GENE MUTATION; HAPLOGROUP; HEART VENTRICLE REMODELING; HUMAN; HUMAN CELL; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR DISEASE; BLACK PERSON; CAUCASIAN; ENERGY METABOLISM; GENETICS; HAPLOTYPE; METABOLISM; MUTATION; OXIDATIVE STRESS;

AFRICAN CONTINENTAL ANCESTRY GROUP; DNA DAMAGE; DNA, MITOCHONDRIAL; ENERGY METABOLISM; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HAPLOTYPES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MALE; MUTATION; OXIDATIVE STRESS;

EID: 84959516478     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.115.001308     Document Type: Article

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