Effects of mtDNA in SHR–mtF344 versus shr conplastic strains on reduced OXPHOS enzyme levels, Insulin resistance, Cardiac hypertrophy, And systolic dysfunction

Physiological Genomics

Volumn 46, Issue 18, 2014, Pages 671-678

  Houštěk, Josef ^a   Vrbacký, Marek ^a   Hejzlarová, KateřIna ^a   Zídek, VáClav ^a   Landa, Vladimír ^a   Šilhavý, Jan ^a   Šimáková, Miroslava ^a   Mlejnek, Petr ^a   Kazdová, Ludmila ^b   Mikšík, Ivan ^a   Neckář, Jan ^a   Papoušek, FrantišEk ^a   Kolář, FrantišEk ^a   Kurtz, Theodore W ^c   Pravenec, Michal ^a  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

^b INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE   (Czech Republic)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Conplastic; Diabetes; Heart mass; Mitochondria; Spontaneously hypertensive rat

Indexed keywords

ADENINE NUCLEOTIDE; AMINO ACID; ENZYME; GLUCOSE; INSULIN; MITOCHONDRIAL DNA; OXPHOS ENZYME; RIBOSOME RNA; TRANSFER RNA; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; FISCHER 344 RAT; HAPLOTYPE; HEART VENTRICLE HYPERTROPHY; HEMODYNAMICS; IMPAIRED GLUCOSE TOLERANCE; INBRED STRAIN; INSULIN RESISTANCE; MITOCHONDRIAL GENOME; NONHUMAN; OXIDATIVE PHOSPHORYLATION; RAT; SINGLE NUCLEOTIDE POLYMORPHISM; SKELETAL MUSCLE; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC DYSFUNCTION; ANIMAL; BLOOD PRESSURE; CARDIOMEGALY; DNA SEQUENCE; DRUG EFFECTS; ELECTROCARDIOGRAPHY; ELECTRON TRANSPORT; GENE DOSAGE; GENETICS; GLUCOSE TOLERANCE TEST; HEART LEFT VENTRICLE FUNCTION; LIPID METABOLISM; MALE; METABOLISM; MITOCHONDRIAL GENE; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; ORGAN SIZE; PATHOPHYSIOLOGY; PHENOTYPE; SYSTOLE;

ADENINE NUCLEOTIDES; ANIMALS; BASE SEQUENCE; BLOOD PRESSURE; CARDIOMEGALY; DNA, MITOCHONDRIAL; ELECTROCARDIOGRAPHY; ELECTRON TRANSPORT; GENE DOSAGE; GENES, MITOCHONDRIAL; GLUCOSE; GLUCOSE TOLERANCE TEST; HAPLOTYPES; INSULIN; INSULIN RESISTANCE; LIPID METABOLISM; MALE; MOLECULAR SEQUENCE DATA; ORGAN SIZE; OXIDATIVE PHOSPHORYLATION; PHENOTYPE; RATS, INBRED F344; RATS, INBRED SHR; RNA, TRANSFER; SEQUENCE ANALYSIS, DNA; SYSTOLE; VENTRICULAR FUNCTION, LEFT;

EID: 84907143245     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00069.2014     Document Type: Article

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