-
1
-
-
34248185454
-
Serrano M. P53: Guardian of the genome and policeman of the oncogenes
-
PMID:17457049
-
Efeyan A, Serrano M. p53: guardian of the genome and policeman of the oncogenes. Cell Cycle 2007; 6:1006-10; PMID:17457049; http://dx.doi.org/10.4161/cc.6.9.4211
-
(2007)
Cell Cycle
, vol.6
, pp. 1006-1010
-
-
Efeyan, A.1
-
2
-
-
33947534030
-
Lane DP. P53 in health and disease
-
PMID:17380161
-
Vousden KH, Lane DP. p53 in health and disease. Nat Rev Mol Cell Biol 2007; 8:275-83; PMID:17380161; http://dx.doi.org/10.1038/nrm2147
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 275-283
-
-
Vousden, K.H.1
-
3
-
-
0028294605
-
WAF1/CIP1 Is Induced in p53-mediated G1 Arrest and Apoptosis
-
PMID:8118801
-
El-Deiry WS, Harper JW, O’Connor PM, Velculescu VE, Canman CE, Jackman J, Pietenpol JA, Burrell M, Hill DE, Wang Y, et al. WAF1/CIP1 Is Induced in p53-mediated G1 Arrest and Apoptosis. Cancer Res 1994; 54:1169-74; PMID:8118801
-
(1994)
Cancer Res
, vol.54
, pp. 1169-1174
-
-
El-Deiry, W.S.1
Harper, J.W.2
O’Connor, P.M.3
Velculescu, V.E.4
Canman, C.E.5
Jackman, J.6
Pietenpol, J.A.7
Burrell, M.8
Hill, D.E.9
Wang, Y.10
-
4
-
-
0026496885
-
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
-
PMID:1423616
-
Kastan MB, Zhan Q, el-Deiry WS, Carrier F, Jacks T, Walsh WV, Plunkett BS, Vogelstein B, Fornace AJ, Jr. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell 1992; 71:587-97; PMID:1423616; http://dx.doi.org/10.1016/0092-8674(92)90593-2
-
(1992)
Cell
, vol.71
, pp. 587-597
-
-
Kastan, M.B.1
Zhan, Q.2
El-Deiry, W.S.3
Carrier, F.4
Jacks, T.5
Walsh, W.V.6
Plunkett, B.S.7
Vogelstein, B.8
Fornace, A.J.9
-
5
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
PMID:7834749
-
Miyashita T, Reed JC. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995; 80:293-9; PMID:7834749; http://dx.doi.org/10.1016/0092-8674(95)90513-8
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
6
-
-
79959854185
-
Transcriptional regulation of cellular senescence
-
PMID:21383691
-
Lanigan F, Geraghty JG, Bracken AP. Transcriptional regulation of cellular senescence. Oncogene 2011; 30:2901-11; PMID:21383691; http://dx.doi.org/10.1038/onc.2011.34
-
(2011)
Oncogene
, vol.30
, pp. 2901-2911
-
-
Lanigan, F.1
Geraghty, J.G.2
Bracken, A.P.3
-
7
-
-
33947125103
-
Genetic dissection of the role of p21Cip1/Waf1 in p53-mediated tumour suppression
-
PMID:16964282
-
Efeyan A, Collado M, Velasco-Miguel S, Serrano M. Genetic dissection of the role of p21Cip1/Waf1 in p53-mediated tumour suppression. Oncogene 2007; 26:1645-9; PMID:16964282; http://dx.doi.org/10.1038/sj.onc.1209972
-
(2007)
Oncogene
, vol.26
, pp. 1645-1649
-
-
Efeyan, A.1
Collado, M.2
Velasco-Miguel, S.3
Serrano, M.4
-
8
-
-
0034626629
-
Loss of p21WAF1/CIP1 accelerates Ras oncogenesis in a transgenic/knockout mammary cancer model
-
PMID:11103935
-
Adnane J, Jackson RJ, Nicosia SV, Cantor AB, Pledger WJ, Sebti SM. Loss of p21WAF1/CIP1 accelerates Ras oncogenesis in a transgenic/knockout mammary cancer model. Oncogene 2000; 19:5338-47; PMID:11103935; http://dx.doi.org/10.1038/sj.onc.1203956
-
(2000)
Oncogene
, vol.19
, pp. 5338-5347
-
-
Adnane, J.1
Jackson, R.J.2
Nicosia, S.V.3
Cantor, A.B.4
Pledger, W.J.5
Sebti, S.M.6
-
9
-
-
0027459198
-
Mdm2 expression is induced by wild type p53 activity
-
PMID:8440237
-
Barak Y, Juven T, Haffner R, Oren M. mdm2 expression is induced by wild type p53 activity. EMBO J 1993; 12:461-8; PMID:8440237
-
(1993)
EMBO J
, vol.12
, pp. 461-468
-
-
Barak, Y.1
Juven, T.2
Haffner, R.3
Oren, M.4
-
10
-
-
0028049474
-
Regulation of mdm2 expression by p53: Alternative promoters produce transcripts with nonidentical translation potential
-
PMID:7958853
-
Barak Y, Gottlieb E, Juven-Gershon T, Oren M. Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential. Gen Dev 1994; 8:1739-49; PMID:7958853; http://dx.doi.org/10.1101/gad.8.15.1739
-
(1994)
Gen Dev
, vol.8
, pp. 1739-1749
-
-
Barak, Y.1
Gottlieb, E.2
Juven-Gershon, T.3
Oren, M.4
-
11
-
-
84883629146
-
The p53- Mdm2 feedback loop protects against DNA damage by inhibiting p53 activity but is dispensable for p53 stability, development, and longevity
-
PMID:23973961
-
Pant V, Xiong S, Jackson JG, Post SM, Abbas HA, Quintas-Cardama A, Hamir AN, Lozano G. The p53- Mdm2 feedback loop protects against DNA damage by inhibiting p53 activity but is dispensable for p53 stability, development, and longevity. Gen Dev 2013; 27:1857-67; PMID:23973961; http://dx.doi.org/10.1101/gad.227249.113
-
(2013)
Gen Dev
, vol.27
, pp. 1857-1867
-
-
Pant, V.1
Xiong, S.2
Jackson, J.G.3
Post, S.M.4
Abbas, H.A.5
Quintas-Cardama, A.6
Hamir, A.N.7
Lozano, G.8
-
12
-
-
51049124035
-
P53 mRNA controls p53 activity by managing Mdm2 functions
-
PMID:19160491
-
Candeias MM, Malbert-Colas L, Powell DJ, Daskalogianni C, Maslon MM, Naski N, Bourougaa K, Calvo F, Fahraeus R. P53 mRNA controls p53 activity by managing Mdm2 functions. Nat Cell Biol 2008; 10:1098-105; PMID:19160491; http://dx.doi.org/10.1038/ncb1770
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1098-1105
-
-
Candeias, M.M.1
Malbert-Colas, L.2
Powell, D.J.3
Daskalogianni, C.4
Maslon, M.M.5
Naski, N.6
Bourougaa, K.7
Calvo, F.8
Fahraeus, R.9
-
13
-
-
60749126297
-
The p53 mRNA-Mdm2 interaction
-
PMID:19106616
-
Naski N, Gajjar M, Bourougaa K, Malbert-Colas L, Fahraeus R, Candeias MM. The p53 mRNA-Mdm2 interaction. Cell Cycle 2009; 8:31-4; PMID:19106616; http://dx.doi.org/10.4161/cc.8.1.7326
-
(2009)
Cell Cycle
, vol.8
, pp. 31-34
-
-
Naski, N.1
Gajjar, M.2
Bourougaa, K.3
Malbert-Colas, L.4
Fahraeus, R.5
Candeias, M.M.6
-
14
-
-
84899867316
-
HDMX folds the nascent p53 mRNA following activation by the ATM kinase
-
PMID:24813712
-
Malbert-Colas L, Ponnuswamy A, Olivares-Illana V, Tournillon AS, Naski N, Fahraeus R. HDMX folds the nascent p53 mRNA following activation by the ATM kinase. Mol Cell 2014; 54:500-11; PMID:24813712; http://dx.doi.org/10.1016/j.molcel.2014.02.035
-
(2014)
Mol Cell
, vol.54
, pp. 500-511
-
-
Malbert-Colas, L.1
Ponnuswamy, A.2
Olivares-Illana, V.3
Tournillon, A.S.4
Naski, N.5
Fahraeus, R.6
-
15
-
-
33745844503
-
Endoplasmic reticulum stress in health and disease
-
PMID:16781856
-
Zhao L, Ackerman SL. Endoplasmic reticulum stress in health and disease. Curr Opin Cell Biol 2006; 18:444-52; PMID:16781856; http://dx.doi.org/10.1016/j.ceb.2006.06.005
-
(2006)
Curr Opin Cell Biol
, vol.18
, pp. 444-452
-
-
Zhao, L.1
Ackerman, S.L.2
-
16
-
-
66749147692
-
Turning off the unfolded protein response: An interplay between the apoptosis machinery and ER stress signaling
-
PMID:19411860
-
Lisbona F, Hetz C. Turning off the unfolded protein response: an interplay between the apoptosis machinery and ER stress signaling. Cell Cycle 2009; 8:1643-4; PMID:19411860; http://dx.doi.org/10.4161/cc.8.11.8637
-
(2009)
Cell Cycle
, vol.8
, pp. 1643-1644
-
-
Lisbona, F.1
Hetz, C.2
-
17
-
-
77950346841
-
Endoplasmic reticulum stress induces G2 cell-cycle arrest via mRNA translation of the p53 isoform p53/47
-
PMID:20385091
-
Bourougaa K, Naski N, Boularan C, Mlynarczyk C, Candeias MM, Marullo S, Fahraeus R. Endoplasmic reticulum stress induces G2 cell-cycle arrest via mRNA translation of the p53 isoform p53/47. Mol Cell 2010; 38:78-88; PMID:20385091; http://dx.doi.org/10.1016/j.molcel.2010.01.041
-
(2010)
Mol Cell
, vol.38
, pp. 78-88
-
-
Bourougaa, K.1
Naski, N.2
Boularan, C.3
Mlynarczyk, C.4
Candeias, M.M.5
Marullo, S.6
Fahraeus, R.7
-
18
-
-
0035881727
-
Suppression of capdependent translation in mitosis
-
PMID:11511540
-
Pyronnet S, Dostie J, Sonenberg N. Suppression of capdependent translation in mitosis. Gen Dev 2001; 15:2083-93; PMID:11511540; http://dx.doi.org/10.1101/gad.889201
-
(2001)
Gen Dev
, vol.15
, pp. 2083-2093
-
-
Pyronnet, S.1
Dostie, J.2
Sonenberg, N.3
-
19
-
-
84923279273
-
Endoplasmic reticulum stress sensitizes cells to DNA damage-induced apoptosis through p53-dependent suppression of p21(CDKN1A)
-
PMID:25295585
-
Mlynarczyk C, Fahraeus R. Endoplasmic reticulum stress sensitizes cells to DNA damage-induced apoptosis through p53-dependent suppression of p21(CDKN1A). Nat Commun 2014; 5:5067; PMID:25295585; http://dx.doi.org/10.1038/ncomms6067
-
(2014)
Nat Commun
, vol.5
, pp. 5067
-
-
Mlynarczyk, C.1
Fahraeus, R.2
-
20
-
-
33750600407
-
Expression of p53 and p53/47 are controlled by alternative mechanisms of messenger RNA translation initiation
-
PMID:16983332
-
Candeias MM, Powell DJ, Roubalova E, Apcher S, Bourougaa K, Vojtesek B, Bruzzoni-Giovanelli H, Fahraeus R. Expression of p53 and p53/47 are controlled by alternative mechanisms of messenger RNA translation initiation. Oncogene 2006; 25:6936-47; PMID:16983332; http://dx.doi.org/10.1038/sj. onc.1209996
-
(2006)
Oncogene
, vol.25
, pp. 6936-6947
-
-
Candeias, M.M.1
Powell, D.J.2
Roubalova, E.3
Apcher, S.4
Bourougaa, K.5
Vojtesek, B.6
Bruzzoni-Giovanelli, H.7
Fahraeus, R.8
-
21
-
-
1042266548
-
GlubaW, Bernier B, Turner T, Mohammad K, Guise T, Sutherland A, ThornerM, ScrableH. Modulation of mammalian life span by the short isoform of p53
-
PMID:14871929
-
Maier B, GlubaW, Bernier B, Turner T, Mohammad K, Guise T, Sutherland A, ThornerM, ScrableH. Modulation of mammalian life span by the short isoform of p53. Gen Dev 2004; 18:306-19; PMID:14871929; http://dx.doi.org/10.1101/gad.1162404
-
(2004)
Gen Dev
, vol.18
, pp. 306-319
-
-
Maier, B.1
-
22
-
-
78049423721
-
Delta40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs
-
PMID:21041409
-
Ungewitter E, Scrable H. Delta40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs. Gen Dev 2010; 24:2408-19; PMID:21041409; http://dx.doi.org/10.1101/gad.1987810
-
(2010)
Gen Dev
, vol.24
, pp. 2408-2419
-
-
Ungewitter, E.1
Scrable, H.2
-
23
-
-
84879685153
-
Scrable H. P53 isoform profiling in glioblastoma and injured brain
-
PMID:22824800
-
Takahashi R, Giannini C, Sarkaria JN, Schroeder M, Rogers J, Mastroeni D, Scrable H. p53 isoform profiling in glioblastoma and injured brain. Oncogene 2013; 32:3165-74; PMID:22824800; http://dx.doi.org/10.1038/onc.2012.322
-
(2013)
Oncogene
, vol.32
, pp. 3165-3174
-
-
Takahashi, R.1
Giannini, C.2
Sarkaria, J.N.3
Schroeder, M.4
Rogers, J.5
Mastroeni, D.6
-
24
-
-
0038751837
-
Transcriptional repression mediated by the p53 tumour suppressor
-
PMID:12719716
-
Ho J, Benchimol S. Transcriptional repression mediated by the p53 tumour suppressor. Cell Death Differ 2003; 10:404-8; PMID:12719716; http://dx.doi.org/10.1038/sj.cdd.4401191
-
(2003)
Cell Death Differ
, vol.10
, pp. 404-408
-
-
Ho, J.1
Benchimol, S.2
-
25
-
-
35548983482
-
Maher LJ, 3rd. P53 RNA interactions: New clues in an old mystery
-
PMID:17804642
-
Riley KJ, Maher LJ, 3rd. p53 RNA interactions: new clues in an old mystery. RNA 2007; 13:1825-33; PMID:17804642; http://dx.doi.org/10.1261/rna.673407
-
(2007)
RNA
, vol.13
, pp. 1825-1833
-
-
Riley, K.J.1
-
26
-
-
34547620115
-
Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: Binding to MDM2, stabilization of p53 protein, and activation of p53 function
-
PMID:17310983
-
Chen D, Zhang Z, Li M, Wang W, Li Y, Rayburn ER, Hill DL, Wang H, Zhang R. Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: binding to MDM2, stabilization of p53 protein, and activation of p53 function. Oncogene 2007; 26:5029-37; PMID:17310983; http://dx.doi.org/10.1038/sj.onc. 1210327
-
(2007)
Oncogene
, vol.26
, pp. 5029-5037
-
-
Chen, D.1
Zhang, Z.2
Li, M.3
Wang, W.4
Li, Y.5
Rayburn, E.R.6
Hill, D.L.7
Wang, H.8
Zhang, R.9
-
27
-
-
53249142431
-
Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway
-
PMID:18560357
-
Horn HF, Vousden KH. Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway. Oncogene 2008; 27:5774-84; PMID:18560357; http://dx.doi.org/10.1038/onc.2008.189
-
(2008)
Oncogene
, vol.27
, pp. 5774-5784
-
-
Horn, H.F.1
Vousden, K.H.2
-
28
-
-
0345276485
-
Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation
-
PMID:14636574
-
Itahana K, Bhat KP, Jin A, Itahana Y, Hawke D, Kobayashi R, Zhang Y. Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation. Mol Cell 2003; 12:1151-64; PMID:14636574; http://dx.doi.org/10.1016/S1097-2765(03)00431-3
-
(2003)
Mol Cell
, vol.12
, pp. 1151-1164
-
-
Itahana, K.1
Bhat, K.P.2
Jin, A.3
Itahana, Y.4
Hawke, D.5
Kobayashi, R.6
Zhang, Y.7
-
29
-
-
0038521256
-
P53 represses RNA polymerase III transcription by targeting TBP and inhibiting promoter occupancy by TFIIIB
-
PMID:12773395
-
Crighton D, Woiwode A, Zhang C, Mandavia N, Morton JP, Warnock LJ, Milner J, White RJ, Johnson DL. p53 represses RNA polymerase III transcription by targeting TBP and inhibiting promoter occupancy by TFIIIB. The EMBO J 2003; 22:2810-20; PMID:12773395; http://dx.doi.org/10.1093/emboj/cdg265
-
(2003)
The EMBO J
, vol.22
, pp. 2810-2820
-
-
Crighton, D.1
Woiwode, A.2
Zhang, C.3
Mandavia, N.4
Morton, J.P.5
Warnock, L.J.6
Milner, J.7
White, R.J.8
Johnson, D.L.9
-
30
-
-
42449139590
-
Stress-dependent changes in the properties of p53 complexes by the alternative translation product p53/47
-
PMID:18414054
-
Powell DJ, Hrstka R, Candeias M, Bourougaa K, Vojtesek B, Fahraeus R. Stress-dependent changes in the properties of p53 complexes by the alternative translation product p53/47. Cell Cycle 2008; 7:950-9; PMID:18414054; http://dx.doi.org/10.4161/cc.7.7.5626
-
(2008)
Cell Cycle
, vol.7
, pp. 950-959
-
-
Powell, D.J.1
Hrstka, R.2
Candeias, M.3
Bourougaa, K.4
Vojtesek, B.5
Fahraeus, R.6
|