High Content Imaging of Early Morphological Signatures Predicts Long Term Mineralization Capacity of Human Mesenchymal Stem Cells upon Osteogenic Induction

Stem Cells

Volumn 34, Issue 4, 2016, Pages 935-947

  Marklein, Ross A ^a   Lo Surdo, Jessica L ^a   Bellayr, Ian H ^a   Godil, Saniya A ^a   Puri, Raj K ^a   Bauer, Steven R ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Automated microscopy; High content imaging; Mesenchymal stem cell; Morphology; Osteogenesis

Indexed keywords

ALKALINE PHOSPHATASE;

ARTICLE; AUTOMATED MICROSCOPY; BONE DEVELOPMENT; CELL DENSITY; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL STRUCTURE; CELL SUBPOPULATION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMAGE ANALYSIS; IN VITRO STUDY; MESENCHYMAL STEM CELL; MICROSCOPY; MINERALIZATION; BONE MARROW CELL; BONE MINERALIZATION; GENE EXPRESSION REGULATION; GENETICS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMA CELL; METABOLISM; PROTEOMICS; REGENERATIVE MEDICINE; ULTRASTRUCTURE;

ALKALINE PHOSPHATASE; BONE MARROW CELLS; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELL PROLIFERATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; OSTEOGENESIS; PROTEOMICS; REGENERATIVE MEDICINE;

EID: 84959489511     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2322     Document Type: Article

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