High-mobility group box-1 protein induces osteogenic phenotype changes in aortic valve interstitial cells

Journal of Thoracic and Cardiovascular Surgery

Volumn 151, Issue 1, 2016, Pages 255-262

  Wang, Bo ^a   Li, Fei ^a   Zhang, Chao ^a   Wei, Guangxia ^b   Liao, Pingping ^a   Dong, Nianguo ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Department of geratology Huangshi Central Hospital   (China)

Author keywords

aortic valve calcification; HMGB1; osteoblastic differentiation; TLR4

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BONE MORPHOGENETIC PROTEIN 2; CYTOKINE; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; OSTEOCALCIN; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; HMGB1 PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR; TLR4 PROTEIN, HUMAN;

ADULT; AORTA VALVE; AORTA VALVE CALCIFICATION; AORTA VALVE DISEASE; AORTIC VALVE INTERSTITIAL CELL; ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; CALCIFICATION; CELL DIFFERENTIATION; CELLS BY BODY ANATOMY; CLINICAL ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INFLAMMATION; MALE; MIDDLE AGED; MOLECULAR PATHOLOGY; OSTEOBLAST; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANTAGONISTS AND INHIBITORS; CALCINOSIS; CASE CONTROL STUDY; CELL CULTURE; DOSE RESPONSE; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; RNA INTERFERENCE; VALVULAR HEART DISEASE;

AORTIC VALVE; CALCINOSIS; CASE-CONTROL STUDIES; CELL DIFFERENTIATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEART VALVE DISEASES; HMGB1 PROTEIN; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MIDDLE AGED; NF-KAPPA B; OSTEOGENESIS; PHENOTYPE; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TRANSFECTION;

EID: 84959487957     PISSN: 00225223     EISSN: 1097685X     Source Type: Journal    
DOI: 10.1016/j.jtcvs.2015.09.077     Document Type: Article

References (34)

1. N.M. Rajamannan Calcific aortic stenosis lessons learned from experimental and clinical studies Arterioscler Thromb Vasc Biol 29 2009 162 168
2. J.D. Miller, R.M. Weiss, and D.D. Heistad Calcific aortic valve stenosis: methods, models, and mechanisms Circ Res 108 2011 1392 1412
3. S. Agarwal, A. Garg, A. Parashar, L.G. Svensson, E.M. Tuzcu, J.L. Navia, and et al. In-hospital mortality and stroke after surgical aortic valve replacement: a nationwide perspective J Thorac Cardiovasc Surg 150 2015 571 578
4. P. Kanellakis, A. Agrotis, T.S. Kyaw, C. Koulis, I. Ahrens, S. Mori, and et al. High-mobility group box protein 1 neutralization reduces development of diet-induced atherosclerosis in apolipoprotein e-deficient mice Arterioscler Thromb Vasc Biol 31 2011 313 319
5. A.W. de Souza, J. Westra, P.C. Limburg, M. Bijl, and C.G. Kallenberg HMGB1 in vascular diseases: its role in vascular inflammation and atherosclerosis Autoimmunol Rev 11 2012 909 917
6. T. Hashimoto, J. Ishii, F. Kitagawa, S. Yamada, K. Hattori, M. Okumura, and et al. Circulating high-mobility group box 1 and cardiovascular mortality in unstable angina and non-ST-segment elevation myocardial infarction Atherosclerosis 221 2012 490 495
7. Y. Luo, S.J. Li, J. Yang, Y.Z. Qiu, and F.P. Chen HMGB1 induces an inflammatory response in endothelial cells via the RAGE-dependent endoplasmic reticulum stress pathway Biochem Biophys Res Commun 438 2013 732 738
8. M. Andrassy, H.C. Volz, J.C. Igwe, B. Funke, S.N. Eichberger, Z. Kaya, and et al. High-mobility group box-1 in ischemia-reperfusion injury of the heart Circulation 117 2008 3216 3226
9. X. Yang, D.A. Fullerton, X. Su, L. Ao, J.C. Cleveland Jr., and X. Meng Pro-osteogenic phenotype of human aortic valve interstitial cells is associated with higher levels of toll-like receptors 2 and 4 and enhanced expression of bone morphogenetic protein 2 J Am Coll Cardiol 53 2009 491 500
10. A.R. Nair, P.J. Ebenezer, Y. Saini, and J. Francis Angiotensin II-induced hypertensive renal inflammation is mediated through HMGB1-TLR4 signaling in rat tubulo-epithelial cells Exp Cell Res 335 2015 238 247
11. R. Jiang, J. Cai, Z. Zhu, D. Chen, J. Wang, Q. Wang, and et al. Hypoxic trophoblast HMGB1 induces endothelial cell hyperpermeability via the TRL-4/caveolin-1 pathway J Immunol 193 2014 5000 5012
12. L.T. Gan, D.M. Van Rooyen, M.E. Koina, R.S. McCuskey, N.C. Teoh, and G.C. Farrell Hepatocyte free cholesterol lipotoxicity results from JNK1-mediated mitochondrial injury and is HMGB1 and TLR4-dependent J Hepatol 61 2014 1376 1384
13. J.S. Park, D. Svetkauskaite, Q.B. He, J.Y. Kim, D. Strassheim, A. Ishizaka, and et al. Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein J Biol Chem 279 2004 7370 7377
14. H.A. Yang, H.S. Hreggvidsdottir, K. Palmblad, H.C. Wang, M. Ochani, J.H. Li, and et al. A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release Proc Natl Acad Sci 107 2010 11942 11947
15. Z.J. Cai, F. Li, W. Gong, W.J. Liu, Q.L. Duan, C. Chen, and et al. Endoplasmic reticulum stress participates in aortic valve calcification in hypercholesterolemic animals Arterioscler Thromb Vasc Biol 33 2013 2345 2354
16. F. Li, Z. Zhao, Z. Cai, N. Dong, and Y. Liu Oxidized low-density lipoprotein promotes osteoblastic differentiation of valvular interstitial cells through RAGE/MAPK Cardiology 130 2015 55 61
17. M. Romani, T.C. Rodman, G. Vidali, and M. Bustin Serological analysis of species specificity in the high mobility group chromosomal proteins J Biol Chem 254 1979 2918 2922
18. X. Meng, L. Ao, Y. Song, A. Babu, X. Yang, M. Wang, and et al. Expression of functional Toll-like receptors 2 and 4 in human aortic valve interstitial cells: potential roles in aortic valve inflammation and stenosis Am J Physiol Cell Physiol 294 2008 C29 C35
19. Q. Zeng, R. Song, L. Ao, M.J. Weyant, J. Lee, D. Xu, and et al. Notch1 promotes the pro-osteogenic response of human aortic valve interstitial cells via modulation of ERK1/2 and nuclear factor-kappaB activation Arterioscler Thromb Vasc Biol 33 2013 1580 1590
20. X. Yang, X. Meng, X. Su, D.C. Mauchley, L. Ao, J.C. Cleveland Jr., and et al. Bone morphogenic protein 2 induces Runx2 and osteopontin expression in human aortic valve interstitial cells: role of Smad1 and extracellular signal-regulated kinase 1/2 J Thorac Cardiovasc Surg 138 2009 1008 1015
21. Q. Zeng, C. Jin, L. Ao, J.C. Cleveland Jr., R. Song, D. Xu, and et al. Cross-talk between the Toll-like receptor 4 and Notch1 pathways augments the inflammatory response in the interstitial cells of stenotic human aortic valves Circulation 126 2012 S222 S230
22. A. Callegari, M.L. Coons, J.L. Ricks, M.E. Rosenfeld, and M. Scatena Increased calcification in osteoprotegerin-deficient smooth muscle cells: dependence on receptor activator of NF-kappaB ligand and interleukin 6 J Vasc Res 51 2014 118 131
23. W.S. Speidl, G. Cimmino, B. Ibanez, S. Elmariah, R. Hutter, M.J. Garcia, and et al. Recombinant apolipoprotein A-I Milano rapidly reverses aortic valve stenosis and decreases leaflet inflammation in an experimental rabbit model Eur Heart J 31 2010 2049 2057
24. Z. Al-Aly, J.S. Shao, C.F. Lai, E. Huang, J. Cai, A. Behrmann, and et al. Aortic Msx2-Wnt calcification cascade is regulated by TNF-alpha-dependent signals in diabetic Ldlr-/- mice Arterioscler Thromb Vasc Biol 27 2007 2589 2596
25. Z. Yu, K. Seya, K. Daitoku, S. Motomura, I. Fukuda, and K. Furukawa Tumor necrosis factor-alpha accelerates the calcification of human aortic valve interstitial cells obtained from patients with calcific aortic valve stenosis via the BMP2-Dlx5 pathway J Pharmacol Exp Ther 337 2011 16 23
26. O.V. Glushkova, M.O. Khrenov, T.V. Novoselova, S.M. Lunin, S.B. Parfenyuk, S.I. Alekseev, and et al. The role of the NF-kappaB, SAPK/JNK, and TLR4 signalling pathways in the responses of RAW 264.7 cells to extremely low-intensity microwaves Int J Radiat Biol 91 2015 321 328
27. C.T. Nguyen, E.H. Kim, T.T. Luong, S. Pyo, and D.K. Rhee TLR4 mediates pneumolysin-induced ATF3 expression through the JNK/p38 pathway in Streptococcus pneumoniae-infected RAW 264.7 cells Mol Cells 38 2015 58 64
28. E.B. Byun, N.Y. Sung, J.N. Park, M.S. Yang, S.H. Park, and E.H. Byun Gamma-irradiated resveratrol negatively regulates LPS-induced MAPK and NF-kappa B signaling through TLR4 in macrophages Int Immunopharmacol 25 2015 249 259
29. X. Su, L. Ao, Y. Shi, T.R. Johnson, D.A. Fullerton, and X. Meng Oxidized low density lipoprotein induces bone morphogenetic protein-2 in coronary artery endothelial cells via Toll-like receptors 2 and 4 J Biol Chem 286 2011 12213 12220
30. R. Song, Q.C. Zeng, L.H. Ao, J.A. Yu, J.C. Cleveland, K.S. Zhao, and et al. Biglycan induces the expression of osteogenic factors in human aortic valve interstitial cells via toll-like receptor-2 Arterioscler Thromb Vasc Biol 32 2012 2711 2720
31. Y. Wang, J. Shan, W. Yang, H. Zheng, and S. Xue High mobility group box 1 (HMGB1) mediates high-glucose-induced calcification in vascular smooth muscle cells of saphenous veins Inflammation 36 2013 1592 1604
32. N.M. Rajamannan Atorvastatin attenuates bone loss and aortic valve atheroma in LDLR mice Cardiology 132 2015 11 15
33. R. De Vecchis, G. Di Biase, C. Esposito, A. Ciccarelli, C. Cioppa, A. Giasi, and et al. Statin use for nonrheumatic calcific aortic valve stenosis: a review with meta-analysis J Cardiovasc Med (Hagerstown) 14 2013 559 567
34. Y. Panahi, A. Sahebkar, H.R. Taghipour, Y. Dadjou, B. Pishgoo, and A.S. Rakhshankhah Atorvastatin therapy is not associated with slowing the progression of aortic stenosis: findings of a randomized controlled trial Clin Lab 59 2013 299 305