Quaternary ammonium disinfectants cause subfertility in mice by targeting both male and female reproductive processes

Reproductive Toxicology

Volumn 59, Issue , 2016, Pages 159-166

  Melin, Vanessa E ^a   Melin, Travis E ^b   Dessify, Brian J ^b   Nguyen, Christina T ^b   Shea, Caroline S ^a   Hrubec, Terry C ^a,b  

^a VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

^b EDWARD VIA COLLEGE OF OSTEOPATHIC MEDICINE   (United States)

Author keywords

Disinfectants; Fertility; Implantation; Ovulation; Quaternary ammonium compounds; Reproduction; Sperm counts

Indexed keywords

ALKYL DIMETHYL BENZYL AMMONIUM CHLORIDE; DIDECYL DIMETHYL AMMONIUM CHLORIDE; DISINFECTANT AGENT; QUATERNARY AMMONIUM DERIVATIVE; UNCLASSIFIED DRUG; BENZALKONIUM; DIDECYLDIMETHYLAMMONIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS LUTEUM; EMBRYO DEATH; ESTRUS CYCLE; FEMALE; MALE; MOUSE; NIDATION; NONHUMAN; OVULATION; REPRODUCTIVE TOXICITY; SPERMATOZOON DENSITY; SPERMATOZOON MOTILITY; SUBFERTILITY; ANIMAL; CELL SURVIVAL; CHEMICALLY INDUCED; DRUG EFFECTS; FEMALE INFERTILITY; FERTILITY; MALE INFERTILITY; PATHOLOGY; PATHOPHYSIOLOGY; PREGNANCY; REPRODUCTION; RISK ASSESSMENT; SPERMATOZOON; SPERMATOZOON COUNT; TIME FACTOR;

ANIMALS; BENZALKONIUM COMPOUNDS; CELL SURVIVAL; DISINFECTANTS; EMBRYO IMPLANTATION; EMBRYO LOSS; ESTROUS CYCLE; FEMALE; FERTILITY; INFERTILITY, FEMALE; INFERTILITY, MALE; MALE; MICE; OVULATION; PREGNANCY; QUATERNARY AMMONIUM COMPOUNDS; REPRODUCTION; RISK ASSESSMENT; SPERM COUNT; SPERM MOTILITY; SPERMATOZOA; TIME FACTORS;

EID: 84959476599     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2015.10.006     Document Type: Article

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