Sperm counts and fertility in men: A rocky road ahead. Science & Society Series on Sex and Science

EMBO Reports

Volumn 13, Issue 5, 2012, Pages 398-403

  Sharpe, Richard M ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIRTH RATE; CONCEPTION; EJACULATION; ENVIRONMENTAL FACTOR; FEMALE FERTILITY; FERTILIZATION; HUMAN; LIFESTYLE; MALE FERTILITY; NONHUMAN; PREGNANCY RATE; PRIORITY JOURNAL; RISK FACTOR; SERTOLI CELL; SEXUAL BEHAVIOR; SPERM PRESERVATION; SPERMATOGENESIS; SPERMATOZOON COUNT; TESTIS SIZE;

ANIMALS; FEMALE; FERTILITY; HUMANS; MALE; SPERM COUNT;

EID: 84860435143     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2012.50     Document Type: Article

References (29)

1. Skakkebaek NE et al (2006) Is human fecundity declining? Int J Androl 29: 2-11
2. Jensen TK, Sbotka T, Hansen MA, Pedersen AT, Lutz W, Skakkebaek NE (2008) Declining trends in conception rates in recent birth cohorts of native Danish women: a possible role of deteriorating male reproductive health. Int J Androl 31: 81-92
3. Sharpe RM, McKinnell C, Kivlin C, Fisher JS (2003) Proliferation and functional maturation of Sertoli cells, and their relevance to disorders of testis function in adulthood. Reproduction 125: 769-784 (Pubitemid 36722545)
4. Bonde JP, Ernst E, Jensen TK, Hjollund NH, Kolstad H, Henriksen TB, Scheike T, Giwercman A, Olsen J, Skakkebaek NE (1998) Relation between semen quality and fertility: a population-based study of 430 first-pregnancy planners. Lancet 354: 1172-1177 (Pubitemid 28458531)
5. Carlsen E, Giwercman A, Keiding N, Skakkebaek NE (1992) Evidence for decreasing quality of semen during past 50 years. BMJ 305: 609-613
6. Swan SH, Elkin EP, Fenster L (2000) The question of declining sperm density revisited: an analysis of 101 studies published 1934-1996. Environ Health Perspect 108: 961-966
7. Oehninger S (2011) Clinical management of male infertility in assisted reproduction: ICSI and beyond. Int J Androl 34: e319-e329
8. Bonde JP, Ramlau-Hansen CH, Olsen J (2011) Trends in sperm counts: the saga continues. Epidemiology 22: 878
9. Jørgensen N, Asklund C, Carlsen E, Skakkebaek NE (2006) Coordinated European investigations of semen quality: results from studies of Scandinavian young men is a matter of concern. Int J Androl 29: 54-61
10. Jensen TK, Jacobsen R, Christensen K, Nielsen NC, Bostofte E (2009) Good semen quality and life expectancy: a cohort study of 43,277 men. Am J Epidemiol 170: 559-565
11. Laughlin GA, Barrett-Connor E, Bergstrom J (2008) Low serum testosterone and mortality in older men. J Clin Endocrinol Metab 93: 68-75
12. Travison TG, Araujo AB, O'Donnell AB, Kupelian V, McKinlay JB (2007) A population-level decline in serum testosterone levels in American men. J Clin Endocrinol Metab 92: 196-202 (Pubitemid 46075010)
13. Sharpe RM (2010) Environmental/lifestyle effects on spermatogenesis. Phil Trans R Soc Lond Ser B 365: 1697-1712
14. Welsh M, Saunders PTK, Fisken M, Scott HM, Hutchison GR, Smith LB, Sharpe RM (2008) Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism. J Clin Invest 118: 1479-1490 (Pubitemid 351500441)
15. Attaman JA, Toth TL, Furtado J, Campos H, Hauser R, Chavarro JE (2012) Dietary fat and semen quality among men attending a fertility clinic. Hum Reprod [Epub ahead of print] doi: 10.1093/humrep/des065
16. Drake AJ, Van den Driesche S, Scott HM, Hutchison G, Seckl JR, Sharpe RM (2009) Glucocorticoids amplify dibutyl phthalate-induced disruption of fetal testosterone production and male reproductive development. Endocrinology 150: 5055-5064
17. Swan SH et al and the Study for Future Families Research Team (2005) Decrease in anogenital distance among male infants with prenatal phthalate exposure. Environ Health Perspect 113: 1056-1061 (Pubitemid 41149638)
18. Eisenberg ML, Hsieh MH, Walters RC, Krasnow R, Lipshultz LI (2011) The relationship between anogenital distance, fatherhood and fertility in adult men. PLoS ONE 6: e18973
19. Skakkebaek NE, Rajpert-De Meyts E, Main KM (2001) Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects. Hum Reprod 16: 972-978 (Pubitemid 32451837)
20. Jensen TK et al (2004) Association of in utero exposure smoking with reduced semen quality and testis size in adulthood: a cross-sectional study of 1,770 young men from the general population in five European countries. Am J Epidemiol 159: 49-58
21. Izawa H, Kohara M, Watanbe G, Taya K, Sagai M (2007) Effects of diesel exhaust particles on the male reproductive system in strains of mice with different aryl hydrocarbon receptor responsiveness. J Reprod Dev 53: 1191-1197 (Pubitemid 351198641)
22. Mocarelli P et al (2011) Perinatal exposure to low doses of dioxin can permanently impair human semen quality. Environ Health Perspect 119: 713-718
23. Gilchrist JM, Moore MB, Andres A, Estroff JA, Badger TM (2010) Ultrasonographic patterns of reproductive organs in infants fed soy formula: comparisons to infants fed breast milk and milk formula. J Pediatr 156: 215-220
24. Main KM et al (2006) Larger testes and higher inhibin B levels in Finnish than in Danish newborn boys. J Clin Endocrinol Metab 91: 2732-2737 (Pubitemid 44024645)
25. Krysiak-Baltyn K et al (2010) Country-specific chemicals signatures of persistent environmental compounds in breast milk. Int J Androl 33: 270-278
26. Bellingham M, McKinnell C, Fowler PA, Amezaga MR, Zhang Z, Rhind SM, Cotinot C, Mandon-Pepin B, Evans NP, Sharpe RM (2012) Fetal and postnatal exposure to sewage sludge chemicals disrupts sperm production in adulthood in a subset of animals. Int J Androl [Epub ahead of print] doi:10.1111/j.1365- 26052011.01234.x
27. Drake AJ, Seckl JR (2011) Transmission of programming effects across generations. Pediatr Endocrinol Rev 9: 566-578
28. Johnson L, Zane RS, Petty CS, Neaves WB (1984) Quantification of the human Sertoli cell population: its distribution, relation to germ cell numbers and age-related decline. Biol Reprod 31: 785-795 (Pubitemid 15184943)
29. Carlsen E, Petersen JH, Andersson AM, Skakkebaek NE (2004) Effects of ejaculatory frequency and season on variations in semen quality. Fertil Steril 82: 358-366 (Pubitemid 39092035)