-
1
-
-
84880271428
-
New developments in the management and treatment of newly diagnosed and relapsed/refractory multiple myeloma patients
-
van de Donk NW, Lokhorst HM. New developments in the management and treatment of newly diagnosed and relapsed/refractory multiple myeloma patients. Expert Opin Pharmacother. 2013;14(12):1569-1573.
-
(2013)
Expert Opin Pharmacother
, vol.14
, Issue.12
, pp. 1569-1573
-
-
Van De Donk, N.W.1
Lokhorst, H.M.2
-
2
-
-
84856719479
-
International Myeloma Working Group. Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib: A multicenter international myeloma working group study
-
Kumar SK, Lee JH, Lahuerta JJ, et al; International Myeloma Working Group. Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib: A multicenter international myeloma working group study. Leukemia. 2012;26(1): 149-157.
-
(2012)
Leukemia
, vol.26
, Issue.1
, pp. 149-157
-
-
Kumar, S.K.1
Lee, J.H.2
Lahuerta, J.J.3
-
3
-
-
84919342495
-
Where we were, where we are, where we are going: Progress in multiple myeloma
-
Bergsagel PL. Where we were, where we are, where we are going: progress in multiple myeloma. Am Soc Clin Oncol Educ Book. 2014; 199-203.
-
(2014)
Am Soc Clin Oncol Educ Book
, pp. 199-203
-
-
Bergsagel, P.L.1
-
4
-
-
84927177719
-
Current treatment landscape for relapsed and/or refractory multiple myeloma
-
Dimopoulos MA, Richardson PG, Moreau P, Anderson KC. Current treatment landscape for relapsed and/or refractory multiple myeloma. Nat Rev Clin Oncol. 2015;12(1):42-54.
-
(2015)
Nat Rev Clin Oncol
, vol.12
, Issue.1
, pp. 42-54
-
-
Dimopoulos, M.A.1
Richardson, P.G.2
Moreau, P.3
Anderson, K.C.4
-
5
-
-
84856701723
-
Monoclonal antibody-based therapy as a new treatment strategy in multiple myeloma
-
van de Donk NW, Kamps S, Mutis T, Lokhorst HM. Monoclonal antibody-based therapy as a new treatment strategy in multiple myeloma. Leukemia. 2012;26(2):199-213.
-
(2012)
Leukemia
, vol.26
, Issue.2
, pp. 199-213
-
-
Van De Donk, N.W.1
Kamps, S.2
Mutis, T.3
Lokhorst, H.M.4
-
6
-
-
84942437054
-
Monoclonal antibodies in multiple myeloma come of age
-
Raje N, Longo DL. Monoclonal Antibodies in Multiple Myeloma Come of Age. N Engl J Med. 2015;373(13):1264-1266.
-
(2015)
N Engl J Med
, vol.373
, Issue.13
, pp. 1264-1266
-
-
Raje, N.1
Longo, D.L.2
-
8
-
-
77951614830
-
Monoclonal antibodies: Versatile platforms for cancer immunotherapy
-
Weiner LM, Surana R, Wang S. Monoclonal antibodies: versatile platforms for cancer immunotherapy. Nat Rev Immunol. 2010;10(5): 317-327.
-
(2010)
Nat Rev Immunol
, vol.10
, Issue.5
, pp. 317-327
-
-
Weiner, L.M.1
Surana, R.2
Wang, S.3
-
9
-
-
78049427830
-
Tumor antigentargeted, monoclonal antibody-based immunotherapy: Clinical response, cellular immunity, and immunoescape
-
Ferris RL, Jaffee EM, Ferrone S. Tumor antigentargeted, monoclonal antibody-based immunotherapy: clinical response, cellular immunity, and immunoescape. J Clin Oncol. 2010;28(28):4390-4399.
-
(2010)
J Clin Oncol
, vol.28
, Issue.28
, pp. 4390-4399
-
-
Ferris, R.L.1
Jaffee, E.M.2
Ferrone, S.3
-
10
-
-
52049104695
-
CS1, a potential new therapeutic antibody target for the treatment of multiple myeloma
-
Hsi ED, Steinle R, Balasa B, et al. CS1, a potential new therapeutic antibody target for the treatment of multiple myeloma. Clin Cancer Res. 2008;14(9):2775-2784.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.9
, pp. 2775-2784
-
-
Hsi, E.D.1
Steinle, R.2
Balasa, B.3
-
11
-
-
51649083849
-
Anti-CS1 humanized monoclonal antibody HuLuc63 inhibits myeloma cell adhesion and induces antibody-dependent cellular cytotoxicity in the bone marrow milieu
-
Tai YT, Dillon M, Song W, et al. Anti-CS1 humanized monoclonal antibody HuLuc63 inhibits myeloma cell adhesion and induces antibody-dependent cellular cytotoxicity in the bone marrow milieu. Blood. 2008;112(4): 1329-1337.
-
(2008)
Blood
, vol.112
, Issue.4
, pp. 1329-1337
-
-
Tai, Y.T.1
Dillon, M.2
Song, W.3
-
12
-
-
84890429971
-
Elotuzumab directly enhances NK cell cytotoxicity against myeloma via CS1 ligation: Evidence for augmented NK cell function complementing ADCC
-
Collins SM, Bakan CE, Swartzel GD, et al. Elotuzumab directly enhances NK cell cytotoxicity against myeloma via CS1 ligation: evidence for augmented NK cell function complementing ADCC. Cancer Immunol Immunother. 2013;62(12):1841-1849.
-
(2013)
Cancer, Immunol Immunother
, vol.62
, Issue.12
, pp. 1841-1849
-
-
Collins, S.M.1
Bakan, C.E.2
Swartzel, G.D.3
-
13
-
-
50349083286
-
Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology
-
Malavasi F, Deaglio S, Funaro A, et al. Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology. Physiol Rev. 2008;88(3):841-886.
-
(2008)
Physiol Rev
, vol.88
, Issue.3
, pp. 841-886
-
-
Malavasi, F.1
Deaglio, S.2
Funaro, A.3
-
14
-
-
84890276750
-
A CD38/CD203a/CD73 ectoenzymatic pathway independent of CD39 drives a novel adenosinergic loop in human T lymphocytes
-
Horenstein AL, Chillemi A, Zaccarello G, et al. A CD38/CD203a/CD73 ectoenzymatic pathway independent of CD39 drives a novel adenosinergic loop in human T lymphocytes. OncoImmunology. 2013;2(9):e26246.
-
(2013)
OncoImmunology
, vol.2
, Issue.9
, pp. e26246
-
-
Horenstein, A.L.1
Chillemi, A.2
Zaccarello, G.3
-
15
-
-
79961073758
-
Editorial: CD38 and retinoids: A step toward a cure
-
Malavasi F. Editorial: CD38 and retinoids: A step toward a cure. J Leukoc Biol. 2011;90(2): 217-219.
-
(2011)
J Leukoc Biol
, vol.90
, Issue.2
, pp. 217-219
-
-
Malavasi, F.1
-
16
-
-
84920501414
-
Unraveling the contribution of ectoenzymes to myeloma life and survival in the bone marrow niche
-
Quarona V, Ferri V, Chillemi A, et al. Unraveling the contribution of ectoenzymes to myeloma life and survival in the bone marrow niche. Ann N Y Acad Sci. 2015;1335:10-22.
-
(2015)
Ann N Y Acad Sci
, vol.1335
, pp. 10-22
-
-
Quarona, V.1
Ferri, V.2
Chillemi, A.3
-
17
-
-
77952419807
-
CD38 increases CXCL12-mediated signals and homing of chronic lymphocytic leukemia cells
-
Vaisitti T, Aydin S, Rossi D, et al. CD38 increases CXCL12-mediated signals and homing of chronic lymphocytic leukemia cells. Leukemia. 2010;24(5):958-969.
-
(2010)
Leukemia
, vol.24
, Issue.5
, pp. 958-969
-
-
Vaisitti, T.1
Aydin, S.2
Rossi, D.3
-
18
-
-
80053350162
-
CD38 and chronic lymphocytic leukemia: A decade later
-
Malavasi F, Deaglio S, Damle R, Cutrona G, Ferrarini M, Chiorazzi N. CD38 and chronic lymphocytic leukemia: A decade later. Blood. 2011;118(13):3470-3478.
-
(2011)
Blood
, vol.118
, Issue.13
, pp. 3470-3478
-
-
Malavasi, F.1
Deaglio, S.2
Damle, R.3
Cutrona, G.4
Ferrarini, M.5
Chiorazzi, N.6
-
19
-
-
84947031216
-
Direct in vitro comparison of daratumumab with surrogate analogs of CD38 antibodies MOR03087, SAR650984 and Ab79
-
abstract Abstract 3474
-
Lammerts van Bueren J, Jakobs D, Kaldenhoven N, et al. Direct in vitro comparison of daratumumab with surrogate analogs of CD38 antibodies MOR03087, SAR650984 and Ab79 [abstract]. Blood. 2014;124(21). Abstract 3474.
-
(2014)
Blood
, vol.124
, Issue.21
-
-
Van Lammerts, B.J.1
Jakobs, D.2
Kaldenhoven, N.3
-
20
-
-
84912126930
-
SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD381 hematologic malignancies
-
Deckert J, Wetzel MC, Bartle LM, et al. SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD381 hematologic malignancies. Clin Cancer Res. 2014;20(17):4574-4583.
-
(2014)
Clin Cancer Res
, vol.20
, Issue.17
, pp. 4574-4583
-
-
Deckert, J.1
Wetzel, M.C.2
Bartle, L.M.3
-
21
-
-
84924546237
-
Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma
-
Overdijk MB, Verploegen S, Bogels M, et al. Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma. MAbs. 2015;7(2):311-321.
-
(2015)
MAbs
, vol.7
, Issue.2
, pp. 311-321
-
-
Overdijk, M.B.1
Verploegen, S.2
Bogels, M.3
-
22
-
-
79251581902
-
Towards effective immunotherapy of myeloma: Enhanced elimination of myeloma cells by combination of lenalidomide with the human CD38 monoclonal antibody daratumumab
-
van der Veer MS, de Weers M, van Kessel B, et al. Towards effective immunotherapy of myeloma: enhanced elimination of myeloma cells by combination of lenalidomide with the human CD38 monoclonal antibody daratumumab. Haematologica. 2011;96(2): 284-290.
-
(2011)
Haematologica
, vol.96
, Issue.2
, pp. 284-290
-
-
Van Der Veer, M.S.1
De Weers, M.2
Van Kessel, B.3
-
23
-
-
79251570884
-
Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors
-
de Weers M, Tai YT, van der Veer MS, et al. Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors. J Immunol. 2011;186(3):1840-1848.
-
(2011)
J Immunol
, vol.186
, Issue.3
, pp. 1840-1848
-
-
De Weers, M.1
Tai, Y.T.2
Van Der Veer, M.S.3
-
24
-
-
84943587393
-
Upregulation of CD38 expression on multiple myeloma cells by all-trans retinoic acid improves the efficacy of daratumumab
-
Nijhof IS, Groen RW, Lokhorst HM, et al. Upregulation of CD38 expression on multiple myeloma cells by all-trans retinoic acid improves the efficacy of daratumumab. Leukemia. 2015; 29(10):2039-2049.
-
(2015)
Leukemia
, vol.29
, Issue.10
, pp. 2039-2049
-
-
Nijhof, I.S.1
Groen, R.W.2
Lokhorst, H.M.3
-
25
-
-
84964255580
-
Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti- KIR antibody IPH2102 and lenalidomide
-
Nijhof IS, Lammerts van Bueren JJ, van Kessel B, et al. Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti- KIR antibody IPH2102 and lenalidomide. Haematologica. 2015;100(2):263-268.
-
(2015)
Haematologica
, vol.100
, Issue.2
, pp. 263-268
-
-
Nijhof, I.S.1
Van Lammerts Bueren, J.J.2
Van Kessel, B.3
-
26
-
-
84904291053
-
The activity of MOR202, a fully human anti-CD38 antibody, is complemented by ADCP and is synergistically enhanced by lenalidomide in vitro and in vivo
-
abstract Abstract 4018
-
Endell J, Boxhammer R, Wurzenberger C, Ness D, Steidl S. The activity of MOR202, a fully human anti-CD38 antibody, is complemented by ADCP and is synergistically enhanced by lenalidomide in vitro and in vivo [abstract]. Blood. 2012;120(21). Abstract 4018.
-
(2012)
Blood
, vol.120
, Issue.21
-
-
Endell, J.1
Boxhammer, R.2
Wurzenberger, C.3
Ness, D.4
Steidl, S.5
-
28
-
-
84959362725
-
-
published online ahead of print September 4, 2015]. Leukemia
-
Jiang H, Acharya C, An G, et al. SAR650984 directly induces multiple myeloma cell death via lysosomal-associated and apoptotic pathways, which is further enhanced by pomalidomide [published online ahead of print September 4, 2015]. Leukemia. doi:10.1038/leu.2015.240.
-
SAR650984 Directly Induces Multiple Myeloma Cell Death via Lysosomal-associated and Apoptotic Pathways, Which is Further Enhanced by Pomalidomide
-
-
Jiang, H.1
Acharya, C.2
An, G.3
-
29
-
-
84864118302
-
A phase 1, multicenter, open-label, dose escalation study of elotuzumab in patients with advanced multiple myeloma
-
Zonder JA, Mohrbacher AF, Singhal S, et al. A phase 1, multicenter, open-label, dose escalation study of elotuzumab in patients with advanced multiple myeloma. Blood. 2012; 120(3):552-559.
-
(2012)
Blood
, vol.120
, Issue.3
, pp. 552-559
-
-
Zonder, J.A.1
Mohrbacher, A.F.2
Singhal, S.3
-
30
-
-
84942436321
-
Targeting CD38 with daratumumab monotherapy in multiple myeloma
-
Lokhorst HM, Plesner T, Laubach JP, et al. Targeting CD38 with daratumumab monotherapy in multiple myeloma. N Engl J Med. 2015;373(13):1207-1219.
-
(2015)
N Engl J Med
, vol.373
, Issue.13
, pp. 1207-1219
-
-
Lokhorst, H.M.1
Plesner, T.2
Laubach, J.P.3
-
31
-
-
84959354811
-
Phase II study of daratumumab (DARA) monotherapy in patients with $3 lines of prior therapy or double refractory multiple myeloma (MM): 54767414MMY2002
-
Sirius [abstract]. Abstract LBA8512. 32. Martin TG, Strickland SA, Glenn M, Zheng W
-
Lonial S, Usmani S, Singha UK, et al. Phase II study of daratumumab (DARA) monotherapy in patients with $3 lines of prior therapy or double refractory multiple myeloma (MM): 54767414MMY2002 (Sirius) [abstract]. J Clin Oncol. 2015;33(suppl). Abstract LBA8512. 32. Martin TG, Strickland SA, Glenn M, Zheng W, .
-
(2015)
J Clin Oncol
, vol.33
-
-
Lonial, S.1
Usmani, S.2
Singha, U.K.3
-
32
-
-
84959334052
-
SAR650984, a CD38 monoclonal antibody in patients with selected CD381 hematological malignancies: Data from a dose-escalation phase I study
-
abstract Abstract 284
-
Daskalakis N, Mikhael JR. SAR650984, a CD38 monoclonal antibody in patients with selected CD381 hematological malignancies: data from a dose-escalation phase I study [abstract]. Blood. 2013;122(21). Abstract 284.
-
(2013)
Blood
, vol.122
, Issue.21
-
-
Daskalakis, N.1
Mikhael, J.R.2
-
33
-
-
84911112328
-
A phase I trial of SAR650984, a CD38 monoclonal antibody, in relapsed or refractory multiple myeloma
-
abstract Abstract 8532
-
Martin T, Hsu K, Strickland SA, Glenn M, Mikhael JR, Charpentier E. A phase I trial of SAR650984, a CD38 monoclonal antibody, in relapsed or refractory multiple myeloma [abstract]. J Clin Oncol. 2014;32(5S). Abstract 8532.
-
(2014)
J Clin Oncol
, vol.32
, Issue.5 S
-
-
Martin, T.1
Hsu, K.2
Strickland, S.A.3
Glenn, M.4
Mikhael, J.R.5
Charpentier, E.6
-
34
-
-
84959327785
-
A phase I/IIa study of the human CD38 antibody MOR202 (MOR03087) in relapsed or refractory multiple myeloma
-
abstract., :, Abstract BP-058
-
Raab M, Chatterjee M, Goldschmidt H, et al. A phase I/IIa study of the human CD38 antibody MOR202 (MOR03087) in relapsed or refractory multiple myeloma [abstract]. Clin Lymphoma Myeloma Leuk. 2015;15(suppl 3):e80. Abstract BP-058.
-
(2015)
Clin Lymphoma Myeloma Leuk
, vol.15
, pp. e80
-
-
Raab, M.1
Chatterjee, M.2
Goldschmidt, H.3
-
35
-
-
84969375698
-
A Phase I/IIa study of the human anti-CD38 antibody MOR202 (MOR03087) in relapsed or refractory multiple myeloma
-
(rrMM) [abstract]., . Abstract 8574
-
Raab S, Goldschmidt HM, Agis H, et al. A phase I/IIa study of the human anti-CD38 antibody MOR202 (MOR03087) in relapsed or refractory multiple myeloma (rrMM) [abstract]. J Clin Oncol. 2015;33(suppl). Abstract 8574.
-
(2015)
J Clin Oncol
, vol.33
-
-
Raab, S.1
Goldschmidt, H.M.2
Agis, H.3
-
36
-
-
84969375704
-
A phase 1/2a study of the human anti-CD38 antibody MOR202 (MOR03087) in relapsed or refractory multiple myeloma
-
abstract Abstract S789
-
Raab S, Goldschmidt H, Agis H, et al. A phase 1/2a study of the human anti-CD38 antibody MOR202 (MOR03087) in relapsed or refractory multiple myeloma [abstract]. Haematologica. 2015;100(suppl 1). Abstract S789.
-
(2015)
Haematologica
, vol.100
-
-
Raab, S.1
Goldschmidt, H.2
Agis, H.3
-
37
-
-
84941342711
-
Preclinical evidence for the therapeutic potential of CD38- targeted immuno-chemotherapy in multiple myeloma patients refractory to lenalidomide and bortezomib
-
Nijhof IS, Groen RW, Noort WA, et al. Preclinical evidence for the therapeutic potential of CD38- targeted immuno-chemotherapy in multiple myeloma patients refractory to lenalidomide and bortezomib. Clin Cancer Res. 2015;21(12): 2802-2810.
-
(2015)
Clin Cancer Res
, vol.21
, Issue.12
, pp. 2802-2810
-
-
Nijhof, I.S.1
Groen, R.W.2
Noort, W.A.3
-
38
-
-
84864061825
-
The therapeutic human CD38 antibody daratumumab improves the anti-myeloma effect of newly emerging multi-drug therapies
-
van der Veer MS, de Weers M, van Kessel B, et al. The therapeutic human CD38 antibody daratumumab improves the anti-myeloma effect of newly emerging multi-drug therapies. Blood Cancer J. 2011;1(10):e41.
-
(2011)
Blood Cancer, J
, vol.1
, Issue.10
, pp. e41
-
-
Van Der Veer, M.S.1
De Weers, M.2
Van Kessel, B.3
-
39
-
-
84935042811
-
Elotuzumab enhances natural killer cell activation and myeloma cell killing through interleukin-2 and TNF-A pathways
-
Balasa B, Yun R, Belmar NA, et al. Elotuzumab enhances natural killer cell activation and myeloma cell killing through interleukin-2 and TNF-a pathways. Cancer Immunol Immunother. 2015;64(1):61-73.
-
(2015)
Cancer Immunol Immunother
, vol.64
, Issue.1
, pp. 61-73
-
-
Balasa, B.1
Yun, R.2
Belmar, N.A.3
-
40
-
-
51649123319
-
Lenalidomide enhances natural killer cell and monocytemediated antibody-dependent cellular cytotoxicity of rituximab-treated CD201 tumor cells
-
Wu L, Adams M, Carter T, et al. lenalidomide enhances natural killer cell and monocytemediated antibody-dependent cellular cytotoxicity of rituximab-treated CD201 tumor cells. Clin Cancer Res. 2008;14(14):4650-4657.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.14
, pp. 4650-4657
-
-
Wu, L.1
Adams, M.2
Carter, T.3
-
41
-
-
84969373459
-
SAR650984 (SAR) directly promotes homotypic adhesionrelated multiple myeloma (MM) cell death and SAR-induced anti-MM activities are enhanced by pomalidomide, more potently than lenalidomide
-
abstract Abstract 2124
-
Jiang H, An G, Acharya C, et al. SAR650984 (SAR) directly promotes homotypic adhesionrelated multiple myeloma (MM) cell death and SAR-induced anti-MM activities are enhanced by pomalidomide, more potently than lenalidomide [abstract]. Blood. 2014;124(21). Abstract 2124.
-
(2014)
Blood
, vol.124
, Issue.21
-
-
Jiang, H.1
An, G.2
Acharya, C.3
-
42
-
-
84933569079
-
ELOQUENT-2 Investigators. Elotuzumab therapy for relapsed or refractory multiple myeloma
-
Lonial S, Dimopoulos M, Palumbo A, et al; ELOQUENT-2 Investigators. Elotuzumab therapy for relapsed or refractory multiple myeloma. N Engl J Med. 2015;373(7):621-631.
-
(2015)
N Engl J Med
, vol.373
, Issue.7
, pp. 621-631
-
-
Lonial, S.1
Dimopoulos, M.2
Palumbo, A.3
-
43
-
-
84958922690
-
A randomized, open-label, phase 2 study of bortezomib and dexamethasone with or without elotuzumab in patients with relapsed/refractory multiple myeloma
-
abstract Abstract S103
-
Jakubowiak A, Offidani M, Pegourie B, et al. A randomized, open-label, phase 2 study of bortezomib and dexamethasone with or without elotuzumab in patients with relapsed/refractory multiple myeloma [abstract]. Haematologica. 2015;100(suppl 1). Abstract S103.
-
(2015)
Haematologica
, vol.100
-
-
Jakubowiak, A.1
Offidani, M.2
Pegourie, B.3
-
44
-
-
84929086780
-
Safety and efficacy of daratumumab with lenalidomide and dexamethasone in relapsed or relapsed, refractory multiple myeloma
-
abstract Abstract 84
-
Plesner T, Arkenau T, Lokhorst HM, et al. Safety and efficacy of daratumumab with lenalidomide and dexamethasone in relapsed or relapsed, refractory multiple myeloma [abstract]. Blood. 2014;124(21). Abstract 84.
-
(2014)
Blood
, vol.124
, Issue.21
-
-
Plesner, T.1
Arkenau, T.2
Lokhorst, H.M.3
-
45
-
-
84968876309
-
Daratumumab in combination with lenalidomide and dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma: Updated results of a phase 1/2 study (GEN503)
-
abstract Abstract 507
-
Plesner T, Arkenau T, Gimsing P, et al. Daratumumab in combination with lenalidomide and dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma: updated results of a phase 1/2 study (GEN503) [abstract]. Blood. 2015;126(23). Abstract 507.
-
(2015)
Blood
, vol.126
, Issue.23
-
-
Plesner, T.1
Arkenau, T.2
Gimsing, P.3
-
46
-
-
84971384724
-
Open-label, multicenter, phase 1b study of daratumumab in combination with pomalidomide and dexamethasone in patients with at least 2 lines of prior therapy and relapsed or relapsed and refractory multiple myeloma [abstract]
-
Abstract 508
-
Chari A, Lonial S, Suvannasankha A, et al. Open-label, multicenter, phase 1b study of daratumumab in combination with pomalidomide and dexamethasone in patients with at least 2 lines of prior therapy and relapsed or relapsed and refractory multiple myeloma [abstract]. Blood. 2015;126(23). Abstract 508.
-
(2015)
Blood
, vol.126
, Issue.23
-
-
Chari, A.1
Lonial, S.2
Suvannasankha, A.3
-
47
-
-
84929080942
-
A phase Ib dose escalation trial of SAR650984 (anti-CD-38 mAb) in combination with lenalidomide and dexamethasone in relapsed/refractory multiple myeloma [abstract
-
Abstract 83
-
Martin TG, Baz R, Benson DM, et al. A phase Ib dose escalation trial of SAR650984 (anti-CD-38 mAb) in combination with lenalidomide and dexamethasone in relapsed/refractory multiple myeloma [abstract]. Blood. 2014;124(21). Abstract 83.
-
(2014)
Blood
, vol.124
, Issue.21
-
-
Martin, T.G.1
Baz, R.2
Benson, D.M.3
-
48
-
-
84863919927
-
Elotuzumab in combination with lenalidomide and low-dose dexamethasone in relapsed or refractory multiple myeloma
-
Lonial S, Vij R, Harousseau JL, et al. Elotuzumab in combination with lenalidomide and low-dose dexamethasone in relapsed or refractory multiple myeloma. J Clin Oncol. 2012; 30(16):1953-1959.
-
(2012)
J Clin Oncol
, vol.30
, Issue.16
, pp. 1953-1959
-
-
Lonial, S.1
Vij, R.2
Harousseau, J.L.3
-
49
-
-
84929081501
-
Final results for the 1703 phase 1b/2 study of elotuzumab in combination with lenalidomide and dexamethasone in patients with relapsed/refractory multiple myeloma [abstract]
-
Abstract 302
-
Richardson PG, Jagannath S, Moreau P, et al. Final results for the 1703 phase 1b/2 study of elotuzumab in combination with lenalidomide and dexamethasone in patients with relapsed/refractory multiple myeloma [abstract]. Blood. 2014;124(21). Abstract 302.
-
(2014)
Blood
, vol.124
, Issue.21
-
-
Richardson, P.G.1
Jagannath, S.2
Moreau, P.3
-
50
-
-
84964968270
-
Elotuzumab in combination with lenalidomide and dexamethasone in patients with relapsed multiple myeloma: Final phase 2 results from the randomised, open-label, phase 1b-2 doseescalation study
-
Richardson P, Jagannath S, Moreau P. Elotuzumab in combination with lenalidomide and dexamethasone in patients with relapsed multiple myeloma: final phase 2 results from the randomised, open-label, phase 1b-2 doseescalation study. Lancet Haematol. 2015;2(12): e516-e527.
-
(2015)
Lancet Haematol
, vol.2
, Issue.12
, pp. e516-e527
-
-
Richardson, P.1
Jagannath, S.2
Moreau, P.3
-
51
-
-
74249089972
-
Mechanism of action of immunomodulatory drugs (IMiDS) in multiple myeloma
-
Quach H, Ritchie D, Stewart AK, et al. Mechanism of action of immunomodulatory drugs (IMiDS) in multiple myeloma. Leukemia. 2010;24(1):22-32.
-
(2010)
Leukemia
, vol.24
, Issue.1
, pp. 22-32
-
-
Quach, H.1
Ritchie, D.2
Stewart, A.K.3
-
52
-
-
84930333012
-
An openlabel, multicenter, phase 1b study of daratumumab in combination with backbone regimens in patients with multiple myeloma
-
abstract Abstract 176
-
Moreau P, Mateos MV, Blade J, et al. An openlabel, multicenter, phase 1b study of daratumumab in combination with backbone regimens in patients with multiple myeloma [abstract]. Blood. 2014;124(21). Abstract 176.
-
(2014)
Blood
, vol.124
, Issue.21
-
-
Moreau, P.1
Mateos, M.V.2
Blade, J.3
-
53
-
-
70349481310
-
Combinatorial efficacy of anti-CS1 monoclonal antibody elotuzumab (HuLuc63) and bortezomib against multiple myeloma
-
van Rhee F, Szmania SM, Dillon M, et al. Combinatorial efficacy of anti-CS1 monoclonal antibody elotuzumab (HuLuc63) and bortezomib against multiple myeloma. Mol Cancer Ther. 2009;8(9):2616-2624.
-
(2009)
Mol Cancer Ther
, vol.8
, Issue.9
, pp. 2616-2624
-
-
Van Rhee, F.1
Szmania, S.M.2
Dillon, M.3
-
54
-
-
85128283908
-
Preclinical chracterization of SAR650984, a humanized anti-CD38 antibody for the treatment of multiple myeloma
-
abstract Abstract P288
-
Cai T, Wetzel M, Nicolazzi C, et al. Preclinical chracterization of SAR650984, a humanized anti-CD38 antibody for the treatment of multiple myeloma [abstract]. Clin Lymphoma Myeloma Leuk. 2013;13(suppl 1). Abstract P288.
-
(2013)
Clin Lymphoma Myeloma Leuk
, vol.13
-
-
Cai, T.1
Wetzel, M.2
Nicolazzi, C.3
-
55
-
-
84862672400
-
Phase I trial of anti-CS1 monoclonal antibody elotuzumab in combination with bortezomib in the treatment of relapsed/refractory multiple myeloma
-
Jakubowiak AJ, Benson DM, Bensinger W, et al. Phase I trial of anti-CS1 monoclonal antibody elotuzumab in combination with bortezomib in the treatment of relapsed/refractory multiple myeloma. J Clin Oncol. 2012;30(16):1960-1965.
-
(2012)
J Clin Oncol
, vol.30
, Issue.16
, pp. 1960-1965
-
-
Jakubowiak, A.J.1
Benson, D.M.2
Bensinger, W.3
-
56
-
-
84941370465
-
Monoclonal antibodies in myeloma
-
Sondergeld P, van de Donk NW, Richardson PG, Plesner T. Monoclonal antibodies in myeloma. Clin Adv Hematol Oncol. 2015;13(9): 599-609.
-
(2015)
Clin Adv, Hematol Oncol
, vol.13
, Issue.9
, pp. 599-609
-
-
Sondergeld, P.1
Van De Donk, N.W.2
Richardson, P.G.3
Plesner, T.4
-
57
-
-
84988620694
-
Expression levels of CD38 and complement inhibitory proteins CD55 and CD59 predcit response to daratumumab in multipe myeloma
-
abstract Abstract S477
-
Nijhof IS, Axel A, Casneuf T, et al. Expression levels of CD38 and complement inhibitory proteins CD55 and CD59 predcit response to daratumumab in multipe myeloma [abstract]. Haematologica. 2015;100(suppl 1). Abstract S477.
-
(2015)
Haematologica
, vol.100
-
-
Nijhof, I.S.1
Axel, A.2
Casneuf, T.3
-
58
-
-
0029849688
-
Identification and characterization of an active soluble form of human CD38 in normal and pathological fluids
-
Funaro A, Horenstein AL, Calosso L, et al. Identification and characterization of an active soluble form of human CD38 in normal and pathological fluids. Int Immunol. 1996;8(11): 1643-1650.
-
(1996)
Int Immunol
, vol.8
, Issue.11
, pp. 1643-1650
-
-
Funaro, A.1
Horenstein, A.L.2
Calosso, L.3
-
59
-
-
84957664777
-
KIR and HLA genotypes influence clinical outcome in multiple myeloma patients treated with SAR650984 (anti- CD38) in combination with lenalidomide and dexamethasone
-
abstract Abstract 2126
-
Marra J, Du J, Hwang J, et al. KIR and HLA genotypes influence clinical outcome in multiple myeloma patients treated with SAR650984 (anti- CD38) in combination with lenalidomide and dexamethasone [abstract]. Blood. 2014;124(21). Abstract 2126.
-
(2014)
Blood
, vol.124
, Issue.21
-
-
Marra, J.1
Du, J.2
Hwang, J.3
-
60
-
-
84860324841
-
Characterizing the impact of renal impairment on the clinical pharmacology of biologics
-
Meibohm B, Zhou H. Characterizing the impact of renal impairment on the clinical pharmacology of biologics. J Clin Pharmacol. 2012;52(1 Suppl): 54S-62S.
-
(2012)
J Clin Pharmacol
, vol.52
, Issue.1
, pp. 54S-62S
-
-
Meibohm, B.1
Zhou, H.2
-
61
-
-
0036830415
-
Treatment of a patient with end-stage renal disease with Rituximab: Pharmacokinetic evaluation suggests Rituximab is not eliminated by hemodialysis
-
Jillella AP, Dainer PM, Kallab AM, Ustun C. Treatment of a patient with end-stage renal disease with Rituximab: pharmacokinetic evaluation suggests Rituximab is not eliminated by hemodialysis. Am J Hematol. 2002;71(3): 219-222.
-
(2002)
Am J Hematol
, vol.71
, Issue.3
, pp. 219-222
-
-
Jillella, A.P.1
Dainer, P.M.2
Kallab, A.M.3
Ustun, C.4
-
62
-
-
84988241358
-
International uniform response criteria for multiple myeloma
-
International Myeloma Working Group
-
Durie BG, Harousseau JL, Miguel JS, et al; International Myeloma Working Group. International uniform response criteria for multiple myeloma. Leukemia. 2006;20(9): 1467-1473.
-
(2006)
Leukemia
, vol.20
, Issue.9
, pp. 1467-1473
-
-
Durie, B.G.1
Harousseau, J.L.2
Miguel, J.S.3
-
63
-
-
84899915546
-
International myeloma working Group recommendations for global myeloma care
-
Ludwig H, Miguel JS, Dimopoulos MA, et al. International Myeloma Working Group recommendations for global myeloma care. Leukemia. 2014;28(5):981-992.
-
(2014)
Leukemia
, vol.28
, Issue.5
, pp. 981-992
-
-
Ludwig, H.1
Miguel, J.S.2
Dimopoulos, M.A.3
-
64
-
-
84957698070
-
Assessing clinical response in multiple myeloma (MM) patients treated with monoclonal antibodies (mAbs): Validation of a daratumumab IFE reflex assay (DIRA) to distinguish malignant M-protein from therapeutic antibody
-
abstract Abstract 8590
-
McCudden CR, Axel A, Slaets D, et al. Assessing clinical response in multiple myeloma (MM) patients treated with monoclonal antibodies (mAbs): validation of a daratumumab IFE reflex assay (DIRA) to distinguish malignant M-protein from therapeutic antibody [abstract]. J Clin Oncol. 2015;33(suppl). Abstract 8590.
-
(2015)
J Clin Oncol
, vol.33
-
-
McCudden, C.R.1
Axel, A.2
Slaets, D.3
-
65
-
-
84904551883
-
Relatively restricted migration of polyclonal IgG4 may mimic a monoclonal gammopathy in IgG4- related disease
-
Jacobs JF, van der Molen RG, Keren DF. Relatively restricted migration of polyclonal IgG4 may mimic a monoclonal gammopathy in IgG4- related disease. Am J Clin Pathol. 2014;142(1): 76-81.
-
(2014)
Am J Clin Pathol
, vol.142
, Issue.1
, pp. 76-81
-
-
Jacobs, J.F.1
Van Der Molen, R.G.2
Keren, D.F.3
-
67
-
-
84962286630
-
Development of clinical assay to mitigate daratumumab, an IgG1- monoclonal antibody, interference with serum immunofixation (IFE) and clinical assessment of M-protein response in multiple myeloma
-
abstract Abstract 2563
-
Axel A, McCudden CR, Xie H, Hall B, Sasser K. Development of clinical assay to mitigate daratumumab, an IgG1- monoclonal antibody, interference with serum immunofixation (IFE) and clinical assessment of M-protein response in multiple myeloma [abstract]. Cancer Res. 2014; 74(19 suppl). Abstract 2563.
-
(2014)
Cancer Res
, vol.74
, Issue.19
-
-
Axel, A.1
McCudden, C.R.2
Xie, H.3
Hall, B.4
Sasser, K.5
-
68
-
-
84919351240
-
Secondary monoclonal gammopathy of undetermined significance after allogeneic stem cell transplantation in multiple myeloma
-
Schmitz MF, Otten HG, Franssen LE, et al. Secondary monoclonal gammopathy of undetermined significance after allogeneic stem cell transplantation in multiple myeloma. Haematologica. 2014;99(12):1846-1853.
-
(2014)
Haematologica
, vol.99
, Issue.12
, pp. 1846-1853
-
-
Schmitz, M.F.1
Otten, H.G.2
Franssen, L.E.3
-
69
-
-
84959327008
-
Eloquent-2: A phase 3, randomized, open-label study of lenalidomide/dexamethasone with or without elotuzumab in patients with relapsed/refractory multiple myeloma
-
abstract Abstract S471
-
Dimopoulos M, Lonial S, Palumbo A, et al. Eloquent-2: A phase 3, randomized, open-label study of lenalidomide/dexamethasone with or without elotuzumab in patients with relapsed/refractory multiple myeloma [abstract]. Haematologica. 2015;100(suppl 1). Abstract S471.
-
(2015)
Haematologica
, vol.100
-
-
Dimopoulos, M.1
Lonial, S.2
Palumbo, A.3
-
70
-
-
84974590627
-
Elotuzumab: Serum protein electrophoresis and immunofixation interference with clinical assessment of M-protein response in relapsed/refractory multiple myelom
-
[abstract]., . Abstract 330
-
Dimopoulos M, Lonial S, Casado L, et al. Elotuzumab: serum protein electrophoresis and immunofixation interference with clinical assessment of M-protein response in relapsed/refractory multiple myeloma [abstract]. Clin Lymphoma Myeloma Leuk. 2015;15(suppl 3). Abstract 330.
-
(2015)
Clin Lymphoma Myeloma Leuk
, vol.15
-
-
Dimopoulos, M.1
Lonial, S.2
Casado, L.3
-
71
-
-
78649827218
-
Interference of monoclonal antibody therapies with serum protein electrophoresis tests
-
McCudden CR, Voorhees PM, Hainsworth SA, et al. Interference of monoclonal antibody therapies with serum protein electrophoresis tests. Clin Chem. 2010;56(12):1897-1899.
-
(2010)
Clin Chem
, vol.56
, Issue.12
, pp. 1897-1899
-
-
McCudden, C.R.1
Voorhees, P.M.2
Hainsworth, S.A.3
-
72
-
-
84908083337
-
Interference of therapeutic monoclonal immunoglobulins in the investigation of M-proteins
-
Ruinemans-Koerts J, Verkroost C, Schmidt- Hieltjes Y, et al. Interference of therapeutic monoclonal immunoglobulins in the investigation of M-proteins. Clin Chem Lab Med. 2014;52(11): e235-e237.
-
(2014)
Clin Chem Lab Med
, vol.52
, Issue.11
, pp. e235-e237
-
-
Ruinemans-Koerts, J.1
Verkroost, C.2
Schmidt-, H.Y.3
-
73
-
-
80052587891
-
Detection of a monoclonal antibody therapy (ofatumumab) by serum protein and immunofixation electrophoresis
-
Genzen JR, Kawaguchi KR, Furman RR. Detection of a monoclonal antibody therapy (ofatumumab) by serum protein and immunofixation electrophoresis. Br J Haematol. 2011;155(1):123-125.
-
(2011)
Br J Haematol
, vol.155
, Issue.1
, pp. 123-125
-
-
Genzen, J.R.1
Kawaguchi, K.R.2
Furman, R.R.3
-
74
-
-
59449099316
-
Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation
-
GEM (Grupo Españ ol de MM)/PETHEMA (Programa para el Estudio de la Terap eutica en Hemopatias Malignas) Cooperative Study Groups
-
Paiva B, Vidriales MB, Cerveŕo J, et al; GEM (Grupo Españ ol de MM)/PETHEMA (Programa para el Estudio de la Terap eutica en Hemopatias Malignas) Cooperative Study Groups. Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation. Blood. 2008;112(10): 4017-4023.
-
(2008)
Blood
, vol.112
, Issue.10
, pp. 4017-4023
-
-
Paiva, B.1
Vidriales, M.B.2
Cerveŕo, J.3
-
75
-
-
84883872187
-
Minimal residual disease assessed by multiparameter flow cytometry in multiple myeloma: Impact on outcome in the Medical Research Council Myeloma IX Study
-
Rawstron AC, Child JA, de Tute RM, et al. Minimal residual disease assessed by multiparameter flow cytometry in multiple myeloma: impact on outcome in the Medical Research Council Myeloma IX Study. J Clin Oncol. 2013;31(20):2540-2547.
-
(2013)
J Clin Oncol
, vol.31
, Issue.20
, pp. 2540-2547
-
-
Rawstron, A.C.1
Child, J.A.2
De Tute, R.M.3
-
76
-
-
84893751030
-
Critical evaluation of ASO RQ-PCR for minimal residual disease evaluation in multiple myeloma
-
Leukemia
-
Puig N, Sarasquete ME, Balanzategui A, et al. Critical evaluation of ASO RQ-PCR for minimal residual disease evaluation in multiple myeloma. A comparative analysis with flow cytometry. Leukemia. 2014;28(2):391-397.
-
(2014)
A Comparative Analysis with Flow Cytometry
, vol.28
, Issue.2
, pp. 391-397
-
-
Puig, N.1
Sarasquete, M.E.2
Balanzategui, A.3
-
77
-
-
84901411165
-
Prognostic value of deep sequencing method for minimal residual disease detection in multiple myeloma
-
Martinez-Lopez J, Lahuerta JJ, Pepin F, et al. Prognostic value of deep sequencing method for minimal residual disease detection in multiple myeloma. Blood. 2014;123(20):3073-3079.
-
(2014)
Blood
, vol.123
, Issue.20
, pp. 3073-3079
-
-
Martinez-Lopez, J.1
Lahuerta, J.J.2
Pepin, F.3
-
78
-
-
84929347438
-
New criteria for response assessment: Role of minimal residual disease in multiple myeloma
-
Paiva B, van Dongen JJ, Orfao A. New criteria for response assessment: role of minimal residual disease in multiple myeloma. Blood. 2015;125(20):3059-3068.
-
(2015)
Blood
, vol.125
, Issue.20
, pp. 3059-3068
-
-
Paiva, B.1
Van Dongen, J.J.2
Orfao, A.3
-
79
-
-
84945318582
-
Assessment of minimal residual disease in myeloma and the need for a consensus approach
-
published online ahead of print July 22, 2015
-
Rawstron AC, Pavia B, Stetler-Stevenson M. Assessment of minimal residual disease in myeloma and the need for a consensus approach [published online ahead of print July 22, 2015]. Cytometry B Clin Cytom. doi:10.1002/cyto.b.21272.
-
Cytometry B Clin Cytom
-
-
Rawstron, A.C.1
Pavia, B.2
Stetler-Stevenson, M.3
-
80
-
-
40849151008
-
European Myeloma network. Report of the European Myeloma network on multiparametric flow cytometry in multiple myeloma and related disorders
-
Rawstron AC, Orfao A, Beksac M, et al; European Myeloma Network. Report of the European Myeloma Network on multiparametric flow cytometry in multiple myeloma and related disorders. Haematologica. 2008;93(3):431-438.
-
(2008)
Haematologica
, vol.93
, Issue.3
, pp. 431-438
-
-
Rawstron, A.C.1
Orfao, A.2
Beksac, M.3
-
82
-
-
85010982932
-
Immunophenotype of normal vs. Myeloma plasma cells: Toward antibody panel specifications for MRD detection in multiple myeloma
-
published online ahead of print June 23, 2015
-
Flores-Montero J, de Tute R, Paiva B, et al. Immunophenotype of normal vs. myeloma plasma cells: Toward antibody panel specifications for MRD detection in multiple myeloma [published online ahead of print June 23, 2015]. Cytometry B Clin Cytom. doi:10.1002/cyto.b.21265.
-
Cytometry B Clin Cytom
-
-
Flores-Montero, J.1
De Tute, R.2
Paiva, B.3
-
83
-
-
84962119024
-
How validated receptor occupancy flow cytometry assays can impact decisions and support drug development
-
published online ahead of print August 31, 2015
-
Moulard M, Ozoux ML. How validated receptor occupancy flow cytometry assays can impact decisions and support drug development [published online ahead of print August 31, 2015]. Cytometry B Clin Cytom. doi:10.1002/cyto.b.21320.
-
Cytometry B Clin Cytom.
-
-
Moulard, M.1
Ozoux, M.L.2
-
84
-
-
84899692195
-
Robust isolation of malignant plasma cells in multiple myeloma
-
Frigyesi I, Adolfsson J, Ali M, et al. Robust isolation of malignant plasma cells in multiple myeloma. Blood. 2014;123(9):1336-1340.
-
(2014)
Blood
, vol.123
, Issue.9
, pp. 1336-1340
-
-
Frigyesi, I.1
Adolfsson, J.2
Ali, M.3
-
85
-
-
84931563891
-
When blood transfusion medicine becomes complicated due to interference by monoclonal antibody therapy
-
Oostendorp M, Lammerts van Bueren JJ, Doshi P, et al. When blood transfusion medicine becomes complicated due to interference by monoclonal antibody therapy. Transfusion. 2015; 55(6 Pt 2):1555-1562.
-
(2015)
Transfusion
, vol.55
, Issue.6
, pp. 1555-1562
-
-
Oostendorp, M.1
Lammerts, V.B.J.J.2
Doshi, P.3
-
86
-
-
84931577511
-
Resolving the daratumumab interference with blood compatibility testing
-
Chapuy CI, Nicholson RT, Aguad MD, et al. Resolving the daratumumab interference with blood compatibility testing. Transfusion. 2015; 55(6 Pt 2):1545-1554.
-
(2015)
Transfusion
, vol.55
, Issue.6
, pp. 1545-1554
-
-
Chapuy, C.I.1
Nicholson, R.T.2
Aguad, M.D.3
-
87
-
-
0027497231
-
A single protein immunologically identified as CD38 displays NAD1 glycohydrolase, ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activities at the outer surface of human erythrocytes
-
Zocchi E, Franco L, Guida L, et al. A single protein immunologically identified as CD38 displays NAD1 glycohydrolase, ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activities at the outer surface of human erythrocytes. Biochem Biophys Res Commun. 1993;196(3):1459-1465.
-
(1993)
Biochem Biophys Res Commun
, vol.196
, Issue.3
, pp. 1459-1465
-
-
Zocchi, E.1
Franco, L.2
Guida, L.3
-
88
-
-
34748888950
-
Erythrocyte CD38 as a prognostic marker in cancer
-
Albeniz I, Demir O, Turker-Sener L, Yalçintepe L, Nurten R, Bermek E. Erythrocyte CD38 as a prognostic marker in cancer. Hematology. 2007; 12(5):409-414.
-
(2007)
Hematology
, vol.12
, Issue.5
, pp. 409-414
-
-
Albeniz, I.1
Demir, O.2
Turker-Sener, L.3
Yalçintepe, L.4
Nurten, R.5
Bermek, E.6
-
89
-
-
84862665040
-
BT062, an antibody-drug conjugate directed against CD138, shows clinical activity in patients with relapsed or relapsed/refractory multiple myeloma
-
abstract Abstract 305
-
Jagannath S, Chanan-Khan A, Heffner LT, et al. BT062, an antibody-drug conjugate directed against CD138, shows clinical activity in patients with relapsed or relapsed/refractory multiple myeloma [abstract]. Blood. 2011;118(21). Abstract 305.
-
(2011)
Blood
, vol.118
, Issue.21
-
-
Jagannath, S.1
Chanan-Khan, A.2
Heffner, L.T.3
-
90
-
-
84879588054
-
BT062, an antibody-drug conjugate directed against CD138, given weekly for 3 weeks in each 4 week cycle: Safety and further evidence of clinical activity
-
abstract Abstract 4042
-
Heffner LT, Jagannath S, Zimmerman TM, et al. BT062, an antibody-drug conjugate directed against CD138, given weekly for 3 weeks in each 4 week cycle: safety and further evidence of clinical activity [abstract]. Blood. 2012;120(21). Abstract 4042.
-
(2012)
Blood
, vol.120
, Issue.21
-
-
Heffner, L.T.1
Jagannath, S.2
Zimmerman, T.M.3
-
91
-
-
84937795971
-
Indatuximab ravtansine (BT062) in combination with lenalidomide and low-dose dexamethasone in patients with relapsed and/or refractory multiple myeloma: Clinical activity in patients already exposed to lenalidomide and bortezomib
-
abstract Abstract 4736
-
Kelly KR, Chanan-Khan A, Heffner LT, et al. Indatuximab ravtansine (BT062) in combination with lenalidomide and low-dose dexamethasone in patients with relapsed and/or refractory multiple myeloma: clinical activity in patients already exposed to lenalidomide and bortezomib [abstract]. Blood. 2014;124(21). Abstract 4736.
-
(2014)
Blood
, vol.124
, Issue.21
-
-
Kelly, K.R.1
Chanan-Khan, A.2
Heffner, L.T.3
-
92
-
-
84894897346
-
Phase I study of lorvotuzumab mertansine (LM, IMGN901) in combination with lenalidomide (Len) and dexamethasone (Dex) in patients with CD56-positive relapsed or relapsed/refractory multiple myeloma
-
MM [abstract]., . Abstract 728
-
Berdeja JG, Hernandez-Ilizaliturri F, Chanan- Khan A, et al. Phase I study of lorvotuzumab mertansine (LM, IMGN901) in combination with lenalidomide (Len) and dexamethasone (Dex) in patients with CD56-positive relapsed or relapsed/refractory multiple myeloma (MM) [abstract]. Blood. 2012;120(21). Abstract 728.
-
(2012)
Blood
, vol.120
, Issue.21
-
-
Berdeja, J.G.1
Hernandez-Ilizaliturri, F.2
Chanan- Khan, A.3
-
93
-
-
79960272171
-
Efficacy analysis from phase I study of lorvotuzumab mertansine (IMGN901), used as monotherapy, in patients with heavily pre-treated CD56-positive multiple myeloma: A preliminary efficacy analysis
-
abstract Abstract 1962
-
Chanan-Khan A, Wolf JL, Garcia J, et al. Efficacy analysis from phase I study of lorvotuzumab mertansine (IMGN901), used as monotherapy, in patients with heavily pre-treated CD56-positive multiple myeloma: A preliminary efficacy analysis [abstract]. Blood. 2010;116(21). Abstract 1962.
-
(2010)
Blood
, vol.116
, Issue.21
-
-
Chanan-Khan, A.1
Wolf, J.L.2
Garcia, J.3
-
94
-
-
49649114804
-
Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
-
Berger R, Rotem-Yehudar R, Slama G, et al. Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies. Clin Cancer Res. 2008;14(10): 3044-3051.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.10
, pp. 3044-3051
-
-
Berger, R.1
Rotem-Yehudar, R.2
Slama, G.3
-
95
-
-
84856764355
-
First-in-human phase I dose escalation study of a humanized anti-CD200 antibody (samalizumab) in patients with advanced stage B cell chronic lymphocytic leukemia (B-CLL) or multiple myeloma
-
MM) [abstract]., . Abstract 2465
-
Mahadevan D, Lanasa MC, Whelden M, et al. First-in-human phase I dose escalation study of a humanized anti-CD200 antibody (samalizumab) in patients with advanced stage B cell chronic lymphocytic leukemia (B-CLL) or multiple myeloma (MM) [abstract]. Blood. 2010; 116(21). Abstract 2465.
-
(2010)
Blood
, vol.116
, Issue.21
-
-
Mahadevan, D.1
Lanasa, M.C.2
Whelden, M.3
-
96
-
-
84938579374
-
A phase 1 (Ph1) trial of MK-3475 combined with lenalidomide (Len) and low-dose dexamethasone (Dex) in patients (pts) with relapsed/refractory multiple myeloma (RRMM)
-
abstract Abstract TPS3117
-
Siegel D, Moreau P, Avigan D, et al. A phase 1 (Ph1) trial of MK-3475 combined with lenalidomide (Len) and low-dose dexamethasone (Dex) in patients (pts) with relapsed/refractory multiple myeloma (RRMM) [abstract]. J Clin Oncol 2014;32(5 suppl). Abstract TPS3117.
-
(2014)
J Clin Oncol
, vol.32
, Issue.5
-
-
Siegel, D.1
Moreau, P.2
Avigan, D.3
-
97
-
-
84925587926
-
Preliminary results of a phase I study of nivolumab (BMS-936558) in patients with relapsed or refractory lymphoid malignancies
-
abstract Abstract 291
-
Lesokhin A, Ansell SM, Armand P, et al. Preliminary results of a phase I study of nivolumab (BMS-936558) in patients with relapsed or refractory lymphoid malignancies [abstract]. Blood. 2014;124(21). Abstract 291.
-
(2014)
Blood
, vol.124
, Issue.21
-
-
Lesokhin, A.1
Ansell, S.M.2
Armand, P.3
-
98
-
-
84962257901
-
Phase Ib study of the novel anti-CXCR4 antibody ulocuplumab (BMS-936564) in combination with lenalidomide plus low-dose dexamethasone, or with bortezomib plus dexamethasone in subjects with relapsed or refractory multiple myeloma
-
abstract Abstract 3483
-
Ghobrial IM, Perez R, Baz R, et al. Phase Ib study of the novel anti-CXCR4 antibody ulocuplumab (BMS-936564) in combination with lenalidomide plus low-dose dexamethasone, or with bortezomib plus dexamethasone in subjects with relapsed or refractory multiple myeloma [abstract]. Blood. 2014;124(21). Abstract 3483.
-
(2014)
Blood
, vol.124
, Issue.21
-
-
Ghobrial, I.M.1
Perez, R.2
Baz, R.3
-
99
-
-
84895813683
-
Phase 1 study of tabalumab, a human anti-BAFF antibody and bortezomib in patients with previously treated multiple myeloma
-
abstract Abstract 447
-
Raje N, Faber EA Jr, Richardson PG, et al. Phase 1 study of tabalumab, a human anti-BAFF antibody and bortezomib in patients with previously treated multiple myeloma [abstract]. Blood. 2012;120(21). Abstract 447.
-
(2012)
Blood
, vol.120
, Issue.21
-
-
Raje, N.1
Faber, E.A.2
Richardson, P.G.3
-
100
-
-
84886407377
-
Phase I, multicentre, dose-escalation trial of monotherapy with milatuzumab (humanized anti-CD74 monoclonal antibody) in relapsed or refractory multiple myeloma
-
Kaufman JL, Niesvizky R, Stadtmauer EA, et al. Phase I, multicentre, dose-escalation trial of monotherapy with milatuzumab (humanized anti-CD74 monoclonal antibody) in relapsed or refractory multiple myeloma. Br J Haematol. 2013;163(4):478-486.
-
(2013)
Br J Haematol
, vol.163
, Issue.4
, pp. 478-486
-
-
Kaufman, J.L.1
Niesvizky, R.2
Stadtmauer, E.A.3
|