-
1
-
-
84959440408
-
Heterozygous mutations in BMP6 pro-peptide lead to inappropriate hepcidin synthesis and moderate iron overload in humans
-
R. Daher, C. Kannengiesser, D. Houamel, and et al. Heterozygous mutations in BMP6 pro-peptide lead to inappropriate hepcidin synthesis and moderate iron overload in humans Gastroenterology 150 2016 672 683
-
(2016)
Gastroenterology
, vol.150
, pp. 672-683
-
-
Daher, R.1
Kannengiesser, C.2
Houamel, D.3
-
2
-
-
0035896642
-
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
-
C.H. Park, E.V. Valore, A.J. Waring, and et al. Hepcidin, a urinary antimicrobial peptide synthesized in the liver J Biol Chem 276 2001 7806 7810
-
(2001)
J Biol Chem
, vol.276
, pp. 7806-7810
-
-
Park, C.H.1
Valore, E.V.2
Waring, A.J.3
-
3
-
-
0035896581
-
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
-
C. Pigeon, G. Ilyin, B. Courselaud, and et al. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload J Biol Chem 276 2001 7811 7819
-
(2001)
J Biol Chem
, vol.276
, pp. 7811-7819
-
-
Pigeon, C.1
Ilyin, G.2
Courselaud, B.3
-
4
-
-
10844258104
-
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
-
E. Nemeth, M.S. Tuttle, J. Powelson, and et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization Science 306 2004 2090 2093
-
(2004)
Science
, vol.306
, pp. 2090-2093
-
-
Nemeth, E.1
Tuttle, M.S.2
Powelson, J.3
-
5
-
-
33644876815
-
A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression
-
R.H. Wang, C. Li, X. Xu, and et al. A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression Cell Metab 2 2005 399 409
-
(2005)
Cell Metab
, vol.2
, pp. 399-409
-
-
Wang, R.H.1
Li, C.2
Xu, X.3
-
6
-
-
80054101329
-
Perturbation of hepcidin expression by BMP type i receptor deletion induces iron overload in mice
-
A.U. Steinbicker, T.B. Bartnikas, L.K. Lohmeyer, and et al. Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice Blood 118 2011 4224 4230
-
(2011)
Blood
, vol.118
, pp. 4224-4230
-
-
Steinbicker, A.U.1
Bartnikas, T.B.2
Lohmeyer, L.K.3
-
7
-
-
46749158788
-
Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin
-
Y. Xia, J.L. Babitt, Y. Sidis, and et al. Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin Blood 111 2008 5195 5204
-
(2008)
Blood
, vol.111
, pp. 5195-5204
-
-
Xia, Y.1
Babitt, J.L.2
Sidis, Y.3
-
8
-
-
79151473137
-
Bone morphogenetic proteins: A critical review
-
B. Bragdon, O. Moseychuk, S. Saldanha, and et al. Bone morphogenetic proteins: a critical review Cell Signal 23 2011 609 620
-
(2011)
Cell Signal
, vol.23
, pp. 609-620
-
-
Bragdon, B.1
Moseychuk, O.2
Saldanha, S.3
-
9
-
-
34447137331
-
Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance
-
J.L. Babitt, F.W. Huang, Y. Xia, and et al. Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance J Clin Invest 117 2007 1933 1939
-
(2007)
J Clin Invest
, vol.117
, pp. 1933-1939
-
-
Babitt, J.L.1
Huang, F.W.2
Xia, Y.3
-
10
-
-
63449103712
-
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
-
B. Andriopoulos Jr., E. Corradini, Y. Xia, and et al. BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism Nat Genet 41 2009 482 487
-
(2009)
Nat Genet
, vol.41
, pp. 482-487
-
-
Andriopoulos, B.1
Corradini, E.2
Xia, Y.3
-
11
-
-
63449122819
-
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
-
D. Meynard, L. Kautz, V. Darnaud, and et al. Lack of the bone morphogenetic protein BMP6 induces massive iron overload Nat Genet 41 2009 478 481
-
(2009)
Nat Genet
, vol.41
, pp. 478-481
-
-
Meynard, D.1
Kautz, L.2
Darnaud, V.3
-
12
-
-
51649096725
-
Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver
-
L. Kautz, D. Meynard, A. Monnier, and et al. Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver Blood 112 2008 1503 1509
-
(2008)
Blood
, vol.112
, pp. 1503-1509
-
-
Kautz, L.1
Meynard, D.2
Monnier, A.3
-
13
-
-
0031149802
-
Bone morphogenetic protein-6 is expressed in nonparenchymal liver cells and upregulated by transforming growth factor-beta 1
-
T. Knittel, P. Fellmer, L. Muller, and et al. Bone morphogenetic protein-6 is expressed in nonparenchymal liver cells and upregulated by transforming growth factor-beta 1 Exp Cell Res 232 1997 263 269
-
(1997)
Exp Cell Res
, vol.232
, pp. 263-269
-
-
Knittel, T.1
Fellmer, P.2
Muller, L.3
-
14
-
-
84875649042
-
Increased iron loading induces Bmp6 expression in the non-parenchymal cells of the liver independent of the BMP-signaling pathway
-
C.A. Enns, R. Ahmed, J. Wang, and et al. Increased iron loading induces Bmp6 expression in the non-parenchymal cells of the liver independent of the BMP-signaling pathway PloS One 8 2013 e60534
-
(2013)
PloS One
, vol.8
, pp. e60534
-
-
Enns, C.A.1
Ahmed, R.2
Wang, J.3
-
15
-
-
84929492922
-
Bmp6 expression in murine liver non parenchymal cells: A mechanism to control their high iron exporter activity and protect hepatocytes from iron overload?
-
M. Rausa, A. Pagani, A. Nai, and et al. Bmp6 expression in murine liver non parenchymal cells: a mechanism to control their high iron exporter activity and protect hepatocytes from iron overload? PloS One 10 2015 e0122696
-
(2015)
PloS One
, vol.10
, pp. e0122696
-
-
Rausa, M.1
Pagani, A.2
Nai, A.3
-
16
-
-
84952639186
-
Differing impact of the deletion of hemochromatosis-associated molecules HFE and TFR2 on the iron phenotype of mice lacking BMP6 or HJV
-
C. Latour, C. Besson-Fournier, D. Meynard, and et al. Differing impact of the deletion of hemochromatosis-associated molecules HFE and TFR2 on the iron phenotype of mice lacking BMP6 or HJV Hepatology 63 2016 126 137
-
(2016)
Hepatology
, vol.63
, pp. 126-137
-
-
Latour, C.1
Besson-Fournier, C.2
Meynard, D.3
-
17
-
-
33646370235
-
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
-
J.L. Babitt, F.W. Huang, D.M. Wrighting, and et al. Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression Nat Genet 38 2006 531 539
-
(2006)
Nat Genet
, vol.38
, pp. 531-539
-
-
Babitt, J.L.1
Huang, F.W.2
Wrighting, D.M.3
-
18
-
-
80052666748
-
Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe
-
E. Corradini, M. Rozier, D. Meynard, and et al. Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe Gastroenterology 141 2011 1907 1914
-
(2011)
Gastroenterology
, vol.141
, pp. 1907-1914
-
-
Corradini, E.1
Rozier, M.2
Meynard, D.3
-
19
-
-
70349494083
-
Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis
-
E. Corradini, C. Garuti, G. Montosi, and et al. Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis Gastroenterology 137 2009 1489 1497
-
(2009)
Gastroenterology
, vol.137
, pp. 1489-1497
-
-
Corradini, E.1
Garuti, C.2
Montosi, G.3
-
20
-
-
77952747961
-
The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivo
-
A.S. Zhang, J. Gao, D.D. Koeberl, and et al. The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivo J Biol Chem 285 2010 16416 16423
-
(2010)
J Biol Chem
, vol.285
, pp. 16416-16423
-
-
Zhang, A.S.1
Gao, J.2
Koeberl, D.D.3
-
21
-
-
35648944164
-
BMP-3 and BMP-6 structures illuminate the nature of binding specificity with receptors
-
G.P. Allendorph, M.J. Isaacs, Y. Kawakami, and et al. BMP-3 and BMP-6 structures illuminate the nature of binding specificity with receptors Biochemistry 46 2007 12238 12247
-
(2007)
Biochemistry
, vol.46
, pp. 12238-12247
-
-
Allendorph, G.P.1
Isaacs, M.J.2
Kawakami, Y.3
-
22
-
-
77956216369
-
BMP-2/6 heterodimer is more effective than BMP-2 or BMP-6 homodimers as inductor of differentiation of human embryonic stem cells
-
E. Valera, M.J. Isaacs, Y. Kawakami, and et al. BMP-2/6 heterodimer is more effective than BMP-2 or BMP-6 homodimers as inductor of differentiation of human embryonic stem cells PloS One 5 2010 e11167
-
(2010)
PloS One
, vol.5
, pp. e11167
-
-
Valera, E.1
Isaacs, M.J.2
Kawakami, Y.3
-
23
-
-
0025373853
-
Requirement for activin A and transforming growth factor-beta 1 pro-regions in homodimer assembly
-
A.M. Gray, and A.J. Mason Requirement for activin A and transforming growth factor-beta 1 pro-regions in homodimer assembly Science 247 1990 1328 1330
-
(1990)
Science
, vol.247
, pp. 1328-1330
-
-
Gray, A.M.1
Mason, A.J.2
-
24
-
-
21644461778
-
Crystal structure of BMP-9 and functional interactions with pro-region and receptors
-
M.A. Brown, Q. Zhao, K.A. Baker, and et al. Crystal structure of BMP-9 and functional interactions with pro-region and receptors J Biol Chem 280 2005 25111 25118
-
(2005)
J Biol Chem
, vol.280
, pp. 25111-25118
-
-
Brown, M.A.1
Zhao, Q.2
Baker, K.A.3
-
25
-
-
84925432612
-
Structure of bone morphogenetic protein 9 procomplex
-
L.Z. Mi, C.T. Brown, Y. Gao, and et al. Structure of bone morphogenetic protein 9 procomplex Proc Natl Acad Sci U S A 112 2015 3710 3715
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 3710-3715
-
-
Mi, L.Z.1
Brown, C.T.2
Gao, Y.3
-
26
-
-
84867575958
-
Subtilisin-like proprotein convertase paired basic amino acid-cleaving enzyme 4 is required for chondrogenic differentiation in ATDC5 cells
-
K. Yuasa, G. Futamatsu, T. Kawano, and et al. Subtilisin-like proprotein convertase paired basic amino acid-cleaving enzyme 4 is required for chondrogenic differentiation in ATDC5 cells FEBS J 279 2012 3997 4009
-
(2012)
FEBS J
, vol.279
, pp. 3997-4009
-
-
Yuasa, K.1
Futamatsu, G.2
Kawano, T.3
|