5-Aminolevulinic Acid-Mediated Sonodynamic Therapy Inhibits RIPK1/RIPK3-Dependent Necroptosis in THP-1-Derived Foam Cells

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Tian, Fang ^a   Yao, Jianting ^a   Yan, Meng ^a   Sun, Xin ^a   Wang, Wei ^a   Gao, Weiwei ^a   Tian, Zhen ^a   Guo, Shuyuan ^a   Dong, Zengxiang ^a   Li, Bicheng ^a   Gao, Tielei ^a   Shan, Peng ^d   Liu, Bing ^d   Wang, Haiyang ^d   Cheng, Jiali ^a   Gao, Qianping ^a   Zhang, Zhiguo ^c   Cao, Wenwu ^c,e   Tian, Ye ^a,b  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b Biopharmaceutical Institute   (China)

^c HARBIN INSTITUTE OF TECHNOLOGY   (China)

^d THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^e PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOLEVULINIC ACID; CASPASE 3; CASPASE 8; IMIDAZOLE DERIVATIVE; INDOLE DERIVATIVE; NECROSTATIN-1; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK1 PROTEIN, HUMAN; RIPK3 PROTEIN, HUMAN;

APOPTOSIS; ATHEROSCLEROSIS; FOAM CELL; HUMAN; METABOLISM; NECROSIS; PATHOLOGY; TUMOR CELL LINE; ULTRASOUND; ULTRASTRUCTURE;

AMINOLEVULINIC ACID; APOPTOSIS; ATHEROSCLEROSIS; CASPASE 3; CASPASE 8; CELL LINE, TUMOR; FOAM CELLS; HUMANS; IMIDAZOLES; INDOLES; NECROSIS; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; ULTRASONIC WAVES;

EID: 84959420218     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep21992     Document Type: Article

References (47)

1. Tabas, I. Macrophage death and defective inflammation resolution in atherosclerosis. Nat Rev Immunol 10, 36-46 (2010).
2. Li, J. et al. Interferon-alpha priming promotes lipid uptake and macrophage-derived foam cell formation: a novel link between interferon-alpha and atherosclerosis in lupus. Arthritis Rheum 63, 492-502 (2011).
3. Walsh, C. M. Grand challenges in cell death and survival: apoptosis vs. necroptosis. Front Cell Dev Biol 2, 3 (2014).
4. O'Donnell, M. A. et al. Caspase 8 inhibits programmed necrosis by processing CYLD. Nat Cell Biol 13, 1437-1442 (2011).
5. Zender, L. et al. Caspase 8 small interfering RNA prevents acute liver failure in mice. Proc Natl Acad Sci USA 100, 7797-7802 (2003).
6. Vandenabeele, P., Galluzzi, L., Vanden Berghe, T. & Kroemer, G. Molecular mechanisms of necroptosis: an ordered cellular explosion. Nat Rev Mol Cell Biol 11, 700-714 (2010).
7. Kroemer, G. et al. Classification of cell death: recommendations of the Nomenclature Committee on Cell Death. Cell Death Differ 12 Suppl 2, 1463-1467 (2005).
8. Lin, J. et al. A role of RIP3-mediated macrophage necrosis in atherosclerosis development. Cell Rep 3, 200-210 (2013).
9. Zhou, W. & Yuan, J. SnapShot: Necroptosis. Cell 158, 464-464 e461 (2014).
10. Gao, X. et al. PEDF and PEDF-derived peptide 44mer protect cardiomyocytes against hypoxia-induced apoptosis and necroptosis via anti-oxidative effect. Sci Rep 4, 5637 (2014).
11. Wu, L. et al. 1,2-benzisothiazol-3-one derivatives as a novel class of small-molecule caspase-3 inhibitors. Bioorg Med Chem 22, 2416-2426 (2014).
12. Cho, Y. S. et al. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 137, 1112-1123 (2009).
13. Trichonas, G. et al. Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis. Proc Natl Acad Sci USA 107, 21695-21700 (2010).
14. Han, J., Zhong, C. Q. & Zhang, D. W. Programmed necrosis: backup to and competitor with apoptosis in the immune system. Nat Immunol 12, 1143-1149 (2011).
15. Kaiser, W. J. et al. RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition. Proc Natl Acad Sci USA 111, 7753-7758 (2014).
16. You, Z. et al. Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice. J Cereb Blood Flow Metab 28, 1564-1573 (2008).
17. Bonapace, L. et al. Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance. J Clin Invest 120, 1310-1323 (2010).
18. Feng, S. et al. Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain. Cell Signal 19, 2056-2067 (2007).
19. Northington, F. J. et al. Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI. J Cereb Blood Flow Metab 31, 178-189 (2011).
20. Degterev, A. et al. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 1, 112-119 (2005).
21. Yumita, N., Nishigaki, R., Umemura, K. & Umemura, S. Hematoporphyrin as a sensitizer of cell-damaging effect of ultrasound. Jpn J Cancer Res 80, 219-222 (1989).
22. Trendowski, M. The promise of sonodynamic therapy. Cancer Metastasis Rev 33, 143-160 (2014).
23. Costley, D. et al. Treating cancer with sonodynamic therapy: a review. Int J Hyperthermia 31, 107-117 (2015).
24. Wood, A. K. & Sehgal, C. M. A review of low-intensity ultrasound for cancer therapy. Ultrasound Med Biol 41, 905-928 (2015).
25. Wang, X. et al. Sonodynamic and photodynamic therapy in advanced breast carcinoma: a report of 3 cases. Integr Cancer Ther 8, 283-287 (2009).
26. Inui, T. et al. Case report: A breast cancer patient treated with GcMAF, sonodynamic therapy and hormone therapy. Anticancer Res 34, 4589-4593 (2014).
27. Li, Z. et al. Rapid stabilisation of atherosclerotic plaque with 5-aminolevulinic acid-mediated sonodynamic therapy. Thromb Haemost 114, 793-803 (2015).
28. Wang, H. et al. The predominant pathway of apoptosis in THP-1 macrophage-derived foam cells induced by 5-aminolevulinic acidmediated sonodynamic therapy is the mitochondria-caspase pathway despite the participation of endoplasmic reticulum stress. Cell Physiol Biochem 33, 1789-1801 (2014).
29. Guo, S. et al. Apoptosis of THP-1 macrophages induced by protoporphyrin IX-mediated sonodynamic therapy. Int J Nanomedicine 8, 2239-2246 (2013).
30. Festjens, N., Vanden Berghe, T., Cornelis, S. & Vandenabeele, P. RIP1, a kinase on the crossroads of a cell's decision to live or die. Cell Death Differ 14, 400-410 (2007).
31. Leppanen, O. et al. ATP depletion in macrophages in the core of advanced rabbit atherosclerotic plaques in vivo. Atherosclerosis 188, 323-330 (2006).
32. Jouan-Lanhouet, S. et al. Necroptosis, in vivo detection in experimental disease models. Semin Cell Dev Biol 35, 2-13 (2014).
33. Newton, K. RIPK1. and RIPK3: critical regulators of inflammation and cell death. Trends Cell Biol 25, 347-353 (2015).
34. Sawai, H. Characterization of TNF-induced caspase-independent necroptosis. Leuk Res 38, 706-713 (2014).
35. Omoto, S. et al. Suppression of RIP3-dependent necroptosis by human cytomegalovirus. J Biol Chem 290, 11635-11648 (2015).
36. Dominic, E. A. et al. Mitochondrial cytopathies and cardiovascular disease. Heart 100, 611-618 (2014).
37. Li, J. et al. The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis. Cell 150, 339-350 (2012).
38. Ofengeim, D. et al. Activation of necroptosis in multiple sclerosis. Cell Rep 10, 1836-1849 (2015).
39. Sawai, H. Differential effects of caspase inhibitors on TNF-induced necroptosis. Biochem Biophys Res Commun 432, 451-455 (2013).
40. Galluzzi, L. & Kroemer, G. Necroptosis: a specialized pathway of programmed necrosis. Cell 135, 1161-1163 (2008).
41. Kaiser, W. J. et al. RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 471, 368-372 (2011).
42. Kuang, A. A., Diehl, G. E., Zhang, J. & Winoto, A. FADD is required for DR4-and DR5-mediated apoptosis: lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts. J Biol Chem 275, 25065-25068 (2000).
43. Dannappel, M. et al. RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. Nature 513, 90-94 (2014).
44. Ribas, J. et al. 7-Bromoindirubin-3'-oxime induces caspase-independent cell death. Oncogene 25, 6304-6318 (2006).
45. Zhu, G. et al. Expression of the RIP-1 gene and its role in growth and invasion of human gallbladder carcinoma. Cell Physiol Biochem 34, 1152-1165 (2014).
46. Sun, L. et al. Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell 148, 213-227 (2012).
47. Zhao, J. et al. Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis. Proc Natl Acad Sci USA 109, 5322-5327 (2012).