Trigonella foenum-graecum Seed Extract, 4-Hydroxyisoleucine, and Metformin Stimulate Proximal Insulin Signaling and Increase Expression of Glycogenic Enzymes and GLUT2 in HepG2 Cells

Metabolic Syndrome and Related Disorders

Volumn 14, Issue 2, 2016, Pages 114-120

  Naicker, Nikita ^a   Nagiah, Savania ^a   Phulukdaree, Alisa ^b   Chuturgoon, Anil ^a  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b UNIVERSITY OF PRETORIA   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYISOLEUCINE; FENUGREEK EXTRACT; GLUCOKINASE; GLUCONIC ACID; GLUCOSE TRANSPORTER 2; GLYCOGEN SYNTHASE; GLYCOGEN SYNTHASE KINASE 3ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN RECEPTOR; INSULIN RECEPTOR BETA; METFORMIN; PROTEIN KINASE B; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; UNCLASSIFIED DRUG; 4-HYDROXYISOLEUCINE; ANTIDIABETIC AGENT; ENZYME; FENUGREEK SEED MEAL; GLYCOGEN SYNTHASE KINASE 3; GSK3B PROTEIN, HUMAN; INSR PROTEIN, HUMAN; INSULIN; ISOLEUCINE; LEUKOCYTE ANTIGEN; PLANT EXTRACT; SLC2A2 PROTEIN, HUMAN;

ANTIDIABETIC ACTIVITY; ARTICLE; FENUGREEK; GLUCOSE TRANSPORT; HEPG2 CELL LINE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; INSULIN RESISTANCE; PLANT SEED; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; COMPARATIVE STUDY; DRUG EFFECTS; ENZYMOLOGY; GENETICS; HEP-G2 CELL LINE; ISOLATION AND PURIFICATION; LIVER CELL; MEDICINAL PLANT; METABOLISM; PHOSPHORYLATION; PHYTOTHERAPY; SIGNAL TRANSDUCTION; TRIGONELLA; UPREGULATION;

ANTIGENS, CD; ENZYMES; GLUCOSE TRANSPORTER TYPE 2; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; HEP G2 CELLS; HEPATOCYTES; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; ISOLEUCINE; METFORMIN; PHOSPHORYLATION; PHYTOTHERAPY; PLANT EXTRACTS; PLANTS, MEDICINAL; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; TRIGONELLA; UP-REGULATION;

EID: 84959228488     PISSN: 15404196     EISSN: 15578518     Source Type: Journal    
DOI: 10.1089/met.2015.0081     Document Type: Article

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