Inhibition of Platelet GPVI Protects Against Myocardial Ischemia-Reperfusion Injury

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 36, Issue 4, 2016, Pages 629-635

  Pachel, Christina ^a   Mathes, Denise ^a,b   Arias Loza, Anahi Paula ^a   Heitzmann, Wolfram ^a   Nordbeck, Peter ^a   Deppermann, Carsten ^c   Lorenz, Viola ^c,d   Hofmann, Ulrich ^a,e   Nieswandt, Bernhard ^c   Frantz, Stefan ^a,e  

^a UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^b JENA UNIVERSITY HOSPITAL   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e MARTIN LUTHER UNIVERSITÄT HALLE WITTENBERG   (Germany)

Author keywords

GPVI collagen receptor; microperfusion; myocardial infarction; myocardial reperfusion injury; platelet inhibition

Indexed keywords

EVANS BLUE; GLYCOPROTEIN VI; MONOCLONAL ANTIBODY; PHOSPHOLIPASE D1; STROMAL INTERACTION MOLECULE 1; TRIPHENYLTETRAZOLIUM; ANTITHROMBOCYTIC AGENT; FIBRINOGEN RECEPTOR; PLATELET MEMBRANE GLYCOPROTEIN VI;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CLOTTING; CALCIUM SIGNALING; CELL INFILTRATION; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY LIGATION; DEGRANULATION; HEART INFARCTION; HEART INFARCTION SIZE; HEART PERFUSION; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; C57BL MOUSE; CARDIAC MUSCLE; COMPARATIVE STUDY; DISEASE MODEL; DRUG EFFECTS; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MICROCIRCULATION; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; PATHOLOGY; PATHOPHYSIOLOGY; THROMBOCYTE; TIME FACTOR;

ANIMALS; ANTIBODIES, MONOCLONAL; BLOOD PLATELETS; CHEMOTAXIS, LEUKOCYTE; CORONARY CIRCULATION; DISEASE MODELS, ANIMAL; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROCIRCULATION; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; PLATELET ACTIVATION; PLATELET AGGREGATION INHIBITORS; PLATELET MEMBRANE GLYCOPROTEINS; TIME FACTORS;

EID: 84959194685     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.115.305873     Document Type: Article

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