The dimeric platelet collagen receptor GPVI-Fc reduces platelet adhesion to activated endothelium and preserves myocardial function after transient ischemia in mice

American Journal of Physiology - Cell Physiology

Volumn 303, Issue 7, 2012, Pages

  Schönberger, Tanja ^a   Ziegler, Melanie ^a   Borst, Oliver ^a   Konrad, Ildiko ^b   Nieswandt, Bernhard ^c   Massberg, Steffen ^b   Ochmann, Carmen ^a   Jürgens, Tobias ^a   Seizer, Peter ^a   Langer, Harald ^a   Münch, Götz ^e   Ungerer, Martin ^e   Preissner, Klaus T ^d   Elvers, Margitta ^a   Gawaz, Meinrad ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d JUSTUS LIEBIG UNIVERSITY   (Germany)

^e NONE

Author keywords

Endothelium; Glycoprotein VI; Myocardial infarction; Platelet; Reperfusion

Indexed keywords

COLLAGEN RECEPTOR; GLYCOPROTEIN VI; HYBRID PROTEIN; IMMUNOGLOBULIN FC FRAGMENT; RECOMBINANT GLYCOPROTEIN VI IMMUNOGLOBULIN FC FRAGMENT FUSION PROTEIN; REVACEPT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG ACTIVITY; DRUG MECHANISM; ENDOTHELIUM; HEART FUNCTION; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; THROMBOCYTE ADHESION;

ANIMALS; CATTLE; CHO CELLS; CRICETINAE; CRICETULUS; ENDOTHELIUM, VASCULAR; HEART; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; ISCHEMIC ATTACK, TRANSIENT; MALE; MICE; MICE, INBRED C57BL; PLATELET ADHESIVENESS; PLATELET MEMBRANE GLYCOPROTEINS; PROTEIN MULTIMERIZATION;

MUS;

EID: 84867081553     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00060.2012     Document Type: Article

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