-
1
-
-
77957576427
-
Trauma mortality in mature trauma systems: Are we doing better? An analysis of trauma mortality patterns, 1997–2008
-
Dutton RP, Stansbury LG, Leone S, Kramer E, Hess JR, Scalea TM (2010) Trauma mortality in mature trauma systems: are we doing better? An analysis of trauma mortality patterns, 1997–2008. J Trauma 69:620–626
-
(2010)
J Trauma
, vol.69
, pp. 620-626
-
-
Dutton, R.P.1
Stansbury, L.G.2
Leone, S.3
Kramer, E.4
Hess, J.R.5
Scalea, T.M.6
-
4
-
-
0032747593
-
Infection in hospitalized trauma patients: Incidence, risk factors, and complications
-
Papia G, McLellan BA, El-Helou P, Louie M, Rachlis A, Szalai JP, Simor AE (1999) Infection in hospitalized trauma patients: incidence, risk factors, and complications. J Trauma 47:923–927
-
(1999)
J Trauma
, vol.47
, pp. 923-927
-
-
Papia, G.1
McLellan, B.A.2
El-Helou, P.3
Louie, M.4
Rachlis, A.5
Szalai, J.P.6
Simor, A.E.7
-
5
-
-
84862908403
-
Inflammation, Host Response to Injury Large-Scale Col-laborative Research Program (2011) A genomic storm in critically injured humans
-
Xiao W, Mindrinos MN, Seok J, Cuschieri J, Cuenca AG, Gao H, Hayden DL, Hennessy L, Moore EE, Minei JP, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Brownstein BH, Mason PH, Baker HV, Finnerty CC, Jeschke MG, Lopez MC, Klein MB, Gamelli RL, Gibran NS, Arnoldo B, Xu W, Zhang Y, Calvano SE, McDonald-Smith GP, Schoenfeld DA, Storey JD, Cobb JP, Warren HS, Moldawer LL, Herndon DN, Lowry SF, Maier RV, Davis RW, Tompkins RG, Inflammation, Host Response to Injury Large-Scale Col-laborative Research Program (2011) A genomic storm in critically injured humans. J Exp Med 208:2581–2590
-
J Exp Med
, vol.208
, pp. 2581-2590
-
-
Xiao, W.1
Mindrinos, M.N.2
Seok, J.3
Cuschieri, J.4
Cuenca, A.G.5
Gao, H.6
Hayden, D.L.7
Hennessy, L.8
Moore, E.E.9
Minei, J.P.10
Bankey, P.E.11
Johnson, J.L.12
Sperry, J.13
Nathens, A.B.14
Billiar, T.R.15
West, M.A.16
Brownstein, B.H.17
Mason, P.H.18
Baker, H.V.19
Finnerty, C.C.20
Jeschke, M.G.21
Lopez, M.C.22
Klein, M.B.23
Gamelli, R.L.24
Gibran, N.S.25
Arnoldo, B.26
Xu, W.27
Zhang, Y.28
Calvano, S.E.29
McDonald-Smith, G.P.30
Schoenfeld, D.A.31
Storey, J.D.32
Cobb, J.P.33
Warren, H.S.34
Moldawer, L.L.35
Herndon, D.N.36
Lowry, S.F.37
Maier, R.V.38
Davis, R.W.39
Tompkins, R.G.40
more..
-
6
-
-
0025100823
-
Monocyte HLA-DR antigen expression characterizes clinical outcome in the trauma patient
-
Hershman MJ, Cheadle WG, Wellhausen SR, Davidson PF, Polk HC Jr (1990) Monocyte HLA-DR antigen expression characterizes clinical outcome in the trauma patient. Br J Surg 77:204–207
-
(1990)
Br J Surg
, vol.77
, pp. 204-207
-
-
Hershman, M.J.1
Cheadle, W.G.2
Wellhausen, S.R.3
Davidson, P.F.4
Polk, H.C.5
-
7
-
-
84908066607
-
Hydrocortisone and fludrocortisone for prevention of hospital-acquired pneumonia in patients with severe traumatic brain injury (Corti-TC): A double-blind, multicentre phase 3, randomised placebo-controlled trial
-
Asehnoune K, Seguin P, Allary J, Feuillet F, Lasocki S, Cook F, Floch H, Chabanne R, Geeraerts T, Roger C, Perrigault PF, Hanouz JL, Lukasze-wicz AC, Biais M, Boucheix P, Dahyot-Fizelier C, Capdevila X, Mahe PJ, Le Maguet P, Paugam-Burtz C, Gergaud S, Plaud B, Constantin JM, Malledant Y, Flet L, Sebille V, Roquilly A, Corti-TC Study Group (2014) Hydrocortisone and fludrocortisone for prevention of hospital-acquired pneumonia in patients with severe traumatic brain injury (Corti-TC): a double-blind, multicentre phase 3, randomised placebo-controlled trial. Lancet Respir Med 2:706–716
-
(2014)
Lancet Respir Med
, vol.2
, pp. 706-716
-
-
Asehnoune, K.1
Seguin, P.2
Allary, J.3
Feuillet, F.4
Lasocki, S.5
Cook, F.6
Floch, H.7
Chabanne, R.8
Geeraerts, T.9
Roger, C.10
Perrigault, P.F.11
Hanouz, J.L.12
Lukasze-Wicz, A.C.13
Biais, M.14
Boucheix, P.15
Dahyot-Fizelier, C.16
Capdevila, X.17
Mahe, P.J.18
Le Maguet, P.19
Paugam-Burtz, C.20
Gergaud, S.21
Plaud, B.22
Constantin, J.M.23
Malledant, Y.24
Flet, L.25
Sebille, V.26
Roquilly, A.27
more..
-
8
-
-
0036594378
-
Increased IL-10 production and HLA-DR suppression in the lungs of injured patients precede the development of nosocomial pneumonia
-
Muehlstedt SG, Lyte M, Rodriguez JL (2002) Increased IL-10 production and HLA-DR suppression in the lungs of injured patients precede the development of nosocomial pneumonia. Shock 17:443–450
-
(2002)
Shock
, vol.17
, pp. 443-450
-
-
Muehlstedt, S.G.1
Lyte, M.2
Rodriguez, J.L.3
-
9
-
-
36549086698
-
Immunoparalysis after multiple trauma
-
Tschoeke SK, Ertel W (2007) Immunoparalysis after multiple trauma. Injury 38:1346–1357
-
(2007)
Injury
, vol.38
, pp. 1346-1357
-
-
Tschoeke, S.K.1
Ertel, W.2
-
10
-
-
84946479421
-
Early daily mHLA-DR monitoring predicts forthcoming sepsis in severe trauma patients
-
Gouel-Cheron A, Allaouchiche B, Floccard B, Rimmele T, Monneret G (2015) Early daily mHLA-DR monitoring predicts forthcoming sepsis in severe trauma patients. Intensive Care Med 41:2229–2230
-
(2015)
Intensive Care Med
, vol.41
, pp. 2229-2230
-
-
Gouel-Cheron, A.1
Allaouchiche, B.2
Floccard, B.3
Rimmele, T.4
Monneret, G.5
-
11
-
-
0033082245
-
Relation of ex vivo stimulated blood cytokine synthesis to post-traumatic sepsis
-
Flach R, Majetschak M, Heukamp T, Jennissen V, Flohe S, Borgermann J, Obertacke U, Schade FU (1999) Relation of ex vivo stimulated blood cytokine synthesis to post-traumatic sepsis. Cytokine 11:173–178
-
(1999)
Cytokine
, vol.11
, pp. 173-178
-
-
Flach, R.1
Majetschak, M.2
Heukamp, T.3
Jennissen, V.4
Flohe, S.5
Borgermann, J.6
Obertacke, U.7
Schade, F.U.8
-
12
-
-
84944454463
-
HLA-DR expression on monocytes is decreased in polytraumatized patients
-
Vester H, Dargatz P, Huber-Wagner S, Biberthaler P, van Griensven M (2015) HLA-DR expression on monocytes is decreased in polytraumatized patients. Eur J Med Res 20:84
-
(2015)
Eur J Med Res
, vol.20
, pp. 84
-
-
Vester, H.1
Dargatz, P.2
Huber-Wagner, S.3
Biberthaler, P.4
van Griensven, M.5
-
13
-
-
82955249233
-
Monocyte deactivation correlates with injury severity score, but not with heme oxygenase-1 levels in trauma patients
-
West SD, Mold C (2012) Monocyte deactivation correlates with injury severity score, but not with heme oxygenase-1 levels in trauma patients. J Surg Res 172:5–10
-
(2012)
J Surg Res
, vol.172
, pp. 5-10
-
-
West, S.D.1
Mold, C.2
-
14
-
-
84871963430
-
DAMPs, PAMPs, and the origins of SIRS in bacterial sepsis
-
Gentile LF, Moldawer LL (2013) DAMPs, PAMPs, and the origins of SIRS in bacterial sepsis. Shock 39:113–114
-
(2013)
Shock
, vol.39
, pp. 113-114
-
-
Gentile, L.F.1
Moldawer, L.L.2
-
15
-
-
77957943307
-
Intravascular danger signals guide neutrophils to sites of sterile inflammation
-
McDonald B, Pittman K, Menezes GB, Hirota SA, Slaba I, Waterhouse CCM, Beck PL, Muruve DA, Kubes P (2010) Intravascular danger signals guide neutrophils to sites of sterile inflammation. Science 330:362–366
-
(2010)
Science
, vol.330
, pp. 362-366
-
-
McDonald, B.1
Pittman, K.2
Menezes, G.B.3
Hirota, S.A.4
Slaba, I.5
Waterhouse, C.C.M.6
Beck, P.L.7
Muruve, D.A.8
Kubes, P.9
-
16
-
-
69949175486
-
Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors
-
Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Grone H-J, Schaefer L (2009) Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. J Biol Chem 284:24035–24048
-
(2009)
J Biol Chem
, vol.284
, pp. 24035-24048
-
-
Babelova, A.1
Moreth, K.2
Tsalastra-Greul, W.3
Zeng-Brouwers, J.4
Eickelberg, O.5
Young, M.F.6
Bruckner, P.7
Pfeilschifter, J.8
Schaefer, R.M.9
Grone, H.-J.10
Schaefer, L.11
-
17
-
-
84899570365
-
Mitochondrial DNA induces inflammation and increases TLR9/NF-kappaB expression in lung tissue
-
Zhang JZ, Liu Z, Liu J, Ren JX, Sun TS (2014) Mitochondrial DNA induces inflammation and increases TLR9/NF-kappaB expression in lung tissue. Int J Mol Med 33:817–824
-
(2014)
Int J Mol Med
, vol.33
, pp. 817-824
-
-
Zhang, J.Z.1
Liu, Z.2
Liu, J.3
Ren, J.X.4
Sun, T.S.5
-
18
-
-
77950275298
-
Circulating mitochondrial DAMPs cause inflammatory responses to injury
-
Zhang Q, Raoof M, Chen Y, Sumi Y, Sursal T, Junger W, Brohi K, Itagaki K, Hauser CJ (2010) Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature 464:104–107
-
(2010)
Nature
, vol.464
, pp. 104-107
-
-
Zhang, Q.1
Raoof, M.2
Chen, Y.3
Sumi, Y.4
Sursal, T.5
Junger, W.6
Brohi, K.7
Itagaki, K.8
Hauser, C.J.9
-
19
-
-
33644513073
-
Cell-free plasma DNA: A marker for apoptosis during hemodialysis
-
Atamaniuk J, Ruzicka K, Stuhlmeier KM, Karimi A, Eigner M, Mueller MM (2006) Cell-free plasma DNA: a marker for apoptosis during hemodialysis. Clin Chem 52:523–526
-
(2006)
Clin Chem
, vol.52
, pp. 523-526
-
-
Atamaniuk, J.1
Ruzicka, K.2
Stuhlmeier, K.M.3
Karimi, A.4
Eigner, M.5
Mueller, M.M.6
-
20
-
-
0036234920
-
Serum levels of Hsp 72 measured early after trauma correlate with sur-vival
-
discussion 617
-
Pittet JF, Lee H, Morabito D, Howard MB, Welch WJ, Mackersie RC (2002) Serum levels of Hsp 72 measured early after trauma correlate with sur-vival. J Trauma 52:611–617 (discussion 617)
-
(2002)
J Trauma
, vol.52
, pp. 611-617
-
-
Pittet, J.F.1
Lee, H.2
Morabito, D.3
Howard, M.B.4
Welch, W.J.5
Mackersie, R.C.6
-
21
-
-
33750819353
-
Extracel-lular heat shock protein-70 induces endotoxin tolerance in THP-1 cells
-
Aneja R, Odoms K, Dunsmore K, Shanley TP, Wong HR (2006) Extracel-lular heat shock protein-70 induces endotoxin tolerance in THP-1 cells. J Immunol 177:7184–7192
-
(2006)
J Immunol
, vol.177
, pp. 7184-7192
-
-
Aneja, R.1
Odoms, K.2
Dunsmore, K.3
Shanley, T.P.4
Wong, H.R.5
-
22
-
-
84862280287
-
Circulating cell-free DNA: An up-coming molecular marker in exercise physiology
-
Breitbach S, Tug S, Simon P (2012) Circulating cell-free DNA: an up-coming molecular marker in exercise physiology. Sports Med 42:565–586
-
(2012)
Sports Med
, vol.42
, pp. 565-586
-
-
Breitbach, S.1
Tug, S.2
Simon, P.3
-
23
-
-
84899128544
-
Immune paralysis in trauma patients; implications for prehospital intervention
-
Kox M, Timmermans K, Vaneker M, Scheffer GJ, Pickkers P (2013) Immune paralysis in trauma patients; implications for prehospital intervention. Crit Care 17:S3–S4
-
(2013)
Crit Care
, vol.17
, pp. S3-S4
-
-
Kox, M.1
Timmermans, K.2
Vaneker, M.3
Scheffer, G.J.4
Pickkers, P.5
-
24
-
-
85089947944
-
Immune paralysis in trauma patients; implications for prehospital intervention
-
Timmermans K, Kox M, Vaneker M, Pickkers P, Scheffer GJ (2014) Immune paralysis in trauma patients; implications for prehospital intervention. Intensive Care Med 40:S246
-
(2014)
Intensive Care Med
, vol.40
, pp. S246
-
-
Timmermans, K.1
Kox, M.2
Vaneker, M.3
Pickkers, P.4
Scheffer, G.J.5
-
25
-
-
84858425597
-
The effects of brain injury on heart rate variability and the innate immune response in critically ill patients
-
Kox M, Vrouwenvelder MQ, Pompe JC, van der Hoeven JG, Pickkers P, Hoedemaekers CW (2012) The effects of brain injury on heart rate variability and the innate immune response in critically ill patients. J Neurotrauma 29:747–755
-
(2012)
J Neurotrauma
, vol.29
, pp. 747-755
-
-
Kox, M.1
Vrouwenvelder, M.Q.2
Pompe, J.C.3
van der Hoeven, J.G.4
Pickkers, P.5
Hoedemaekers, C.W.6
-
26
-
-
4644368801
-
Peptidylpropyl isomerase B (PPIB): A suitable reference gene for mRNA quantification in peripheral whole blood
-
Pachot A, Blond JL, Mougin B, Miossec P (2004) Peptidylpropyl isomerase B (PPIB): a suitable reference gene for mRNA quantification in peripheral whole blood. J Biotechnol 114:121–124
-
(2004)
J Biotechnol
, vol.114
, pp. 121-124
-
-
Pachot, A.1
Blond, J.L.2
Mougin, B.3
Miossec, P.4
-
27
-
-
84884967732
-
Preliminary results in quantitation of HLA-DRA by real-time PCR: A promis-ing approach to identify immunosuppression in sepsis
-
Cajander S, Backman A, Tina E, Stralin K, Soderquist B, Kallman J (2013) Preliminary results in quantitation of HLA-DRA by real-time PCR: a promis-ing approach to identify immunosuppression in sepsis. Crit Care 17:R223
-
(2013)
Crit Care
, vol.17
, pp. R223
-
-
Cajander, S.1
Backman, A.2
Tina, E.3
Stralin, K.4
Soderquist, B.5
Kallman, J.6
-
28
-
-
2442501750
-
Monocyte human leukocyte antigen-DR transcriptional downregulation by cortisol during septic shock
-
Le Tulzo Y, Pangault C, Amiot L, Guilloux V, Tribut O, Arvieux C, Camus C, Fauchet R, Thomas R, Drenou B (2004) Monocyte human leukocyte antigen-DR transcriptional downregulation by cortisol during septic shock. Am J Respir Crit Care Med 169:1144–1151
-
(2004)
Am J Respir Crit Care Med
, vol.169
, pp. 1144-1151
-
-
Le Tulzo, Y.1
Pangault, C.2
Amiot, L.3
Guilloux, V.4
Tribut, O.5
Arvieux, C.6
Camus, C.7
Fauchet, R.8
Thomas, R.9
Drenou, B.10
-
29
-
-
12244283722
-
Messenger RNA expression of major histocompatibility complex class II genes in whole blood from septic shock patients
-
(discussion 236–237)
-
Pachot A, Monneret G, Brion A, Venet F, Bohe J, Bienvenu J, Mougin B, Lepape A (2005) Messenger RNA expression of major histocompatibility complex class II genes in whole blood from septic shock patients. Crit Care Med 33:31–38 (discussion 236–237)
-
(2005)
Crit Care Med
, vol.33
, pp. 31-38
-
-
Pachot, A.1
Monneret, G.2
Brion, A.3
Venet, F.4
Bohe, J.5
Bienvenu, J.6
Mougin, B.7
Lepape, A.8
-
30
-
-
0003976359
-
-
5th edn, Allyn & Bacon, Needham Heights
-
Tabachnick BG, Fidell LS (2007) Using multivariate statistics, 5th edn, Allyn & Bacon, Needham Heights, p 635
-
(2007)
Using Multivariate Statistics
, pp. 635
-
-
Tabachnick, B.G.1
Fidell, L.S.2
-
31
-
-
70349653291
-
Monocytic HLA-DR expression in intensive care patients: Interest for prognosis and secondary infection prediction
-
Lukaszewicz AC, Grienay M, Resche-Rigon M, Pirracchio R, Faivre V, Boval B, Payen D (2009) Monocytic HLA-DR expression in intensive care patients: interest for prognosis and secondary infection prediction. Crit Care Med 37:2746–2752
-
(2009)
Crit Care Med
, vol.37
, pp. 2746-2752
-
-
Lukaszewicz, A.C.1
Grienay, M.2
Resche-Rigon, M.3
Pirracchio, R.4
Faivre, V.5
Boval, B.6
Payen, D.7
-
32
-
-
1642533459
-
Plasma mitochon-drial DNA concentrations after trauma
-
Lam NY, Rainer TH, Chiu RW, Joynt GM, Lo YM (2004) Plasma mitochon-drial DNA concentrations after trauma. Clin Chem 50:213–216
-
(2004)
Clin Chem
, vol.50
, pp. 213-216
-
-
Lam, N.Y.1
Rainer, T.H.2
Chiu, R.W.3
Joynt, G.M.4
Lo, Y.M.5
-
33
-
-
0037407143
-
Quan-titative analysis of circulating mitochondrial DNA in plasma
-
Chiu RW, Chan LY, Lam NY, Tsui NB, Ng EK, Rainer TH, Lo YM (2003) Quan-titative analysis of circulating mitochondrial DNA in plasma. Clin Chem 49:719–726
-
(2003)
Clin Chem
, vol.49
, pp. 719-726
-
-
Chiu, R.W.1
Chan, L.Y.2
Lam, N.Y.3
Tsui, N.B.4
Ng, E.K.5
Rainer, T.H.6
Lo, Y.M.7
-
34
-
-
0036310152
-
Immunoparalysis in patients with severe trauma and the effect of inhaled interferon-gamma
-
Nakos G, Malamou-Mitsi VD, Lachana A, Karassavoglou A, Kitsiouli E, Agnandi N, Lekka ME (2002) Immunoparalysis in patients with severe trauma and the effect of inhaled interferon-gamma. Crit Care Med 30:1488–1494
-
(2002)
Crit Care Med
, vol.30
, pp. 1488-1494
-
-
Nakos, G.1
Malamou-Mitsi, V.D.2
Lachana, A.3
Karassavoglou, A.4
Kitsiouli, E.5
Agnandi, N.6
Lekka, M.E.7
-
35
-
-
0026510903
-
Biological properties of interleukin 10
-
Howard M, O’Garra A (1992) Biological properties of interleukin 10. Immu-nol Today 13:198–200
-
(1992)
Immu-Nol Today
, vol.13
, pp. 198-200
-
-
Howard, M.1
O’Garra, A.2
-
36
-
-
11144344922
-
Surgical trauma: Hyperinflammation versus immunosuppression?
-
Menger MD, Vollmar B (2004) Surgical trauma: hyperinflammation versus immunosuppression? Langenbecks Arch Surg 389:475–484
-
(2004)
Langenbecks Arch Surg
, vol.389
, pp. 475-484
-
-
Menger, M.D.1
Vollmar, B.2
-
37
-
-
85028203484
-
Interleukin-6 and its receptors: A highly regulated and dynamic system
-
Wolf J, Rose-John S, Garbers C (2014) Interleukin-6 and its receptors: a highly regulated and dynamic system. Cytokine 70:11–20
-
(2014)
Cytokine
, vol.70
, pp. 11-20
-
-
Wolf, J.1
Rose-John, S.2
Garbers, C.3
-
38
-
-
84879562427
-
Immunotherapy for the adjunctive treatment of sepsis: From immuno-suppression to immunostimulation
-
Leentjens J, Kox M, van der Hoeven JG, Netea MG, Pickkers P (2013) Immunotherapy for the adjunctive treatment of sepsis: from immuno-suppression to immunostimulation. Time for a paradigm change? Am J Respir Crit Care Med 187:1287–1293
-
(2013)
Time for a Paradigm Change? Am J Respir Crit Care Med
, vol.187
, pp. 1287-1293
-
-
Leentjens, J.1
Kox, M.2
van der Hoeven, J.G.3
Netea, M.G.4
Pickkers, P.5
-
39
-
-
84891639053
-
Decreased HLA-DR antigen-associated invariant chain (CD74) mRNA expression predicts mortality after septic shock
-
Cazalis MA, Friggeri A, Cave L, Demaret J, Barbalat V, Cerrato E, Lepape A, Pachot A, Monneret G, Venet F (2013) Decreased HLA-DR antigen-associated invariant chain (CD74) mRNA expression predicts mortality after septic shock. Crit Care 17:R287
-
(2013)
Crit Care
, vol.17
, pp. R287
-
-
Cazalis, M.A.1
Friggeri, A.2
Cave, L.3
Demaret, J.4
Barbalat, V.5
Cerrato, E.6
Lepape, A.7
Pachot, A.8
Monneret, G.9
Venet, F.10
-
40
-
-
84902273600
-
Cellular signaling in the aging immune system
-
Fulop T, Le Page A, Fortin C, Witkowski JM, Dupuis G, Larbi A (2014) Cellular signaling in the aging immune system. Curr Opin Immunol 29:105–111
-
(2014)
Curr Opin Immunol
, vol.29
, pp. 105-111
-
-
Fulop, T.1
Le Page, A.2
Fortin, C.3
Witkowski, J.M.4
Dupuis, G.5
Larbi, A.6
|