Hydrocortisone and fludrocortisone for prevention of hospital-acquired pneumonia in patients with severe traumatic brain injury (Corti-TC): A double-blind, multicentre phase 3, randomised placebo-controlled trial

The Lancet Respiratory Medicine

Volumn 2, Issue 9, 2014, Pages 706-716

  Asehnoune, Karim ^a   Seguin, Philippe ^b   Allary, Jeremy ^c   Feuillet, Fanny ^a,d   Lasocki, Sigismond ^e   Cook, Fabrice ^f   Floch, Hervé ^g   Chabanne, Russell ^h   Geeraerts, Thomas ⁱ   Roger, Claire ^j   Perrigault, Pierre F ^k   Hanouz, Jean L ^l   Lukaszewicz, Anne C ^m   Biais, Matthieu ⁿ   Boucheix, Perrine ^o   Dahyot Fizelier, Claire ^p   Capdevila, Xavier ^q   Mahe, Pierre J ^a   Maguet, Pascale Le ^b   Paugam Burtz, Catherine ^c   Gergaud, Soizic ^e   Plaud, Benoit ^f   Constantin, Jean M ^h   Malledant, Yannick ^b   Flet, Laurent ^a   Sebille, Véronique ^a,d   Roquilly, Antoine ^a   more..

^a NANTES UNIVERSITY HOSPITAL   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

^c BEAUJON HOSPITAL   (France)

^d Universite de Nantes   (France)

^e ANGERS UNIVERSITY HOSPITAL   (France)

^f HENRI MONDOR HOSPITAL   (France)

^g BREST UNIVERSITY HOSPITAL   (France)

^h UNIVERSITY HOSPITAL OF CLERMONT FERRAND   (France)

ⁱ TOULOUSE UNIVERSITY HOSPITAL   (France)

^j NÎMES UNIVERSITY HOSPITAL   (France)

^k GUI DE CHAULIAC HOSPITAL   (France)

^l CAEN UNIVERSITY HOSPITAL   (France)

^m HÔPITAL LARIBOISIÈRE   (France)

ⁿ BORDEAUX UNIVERSITY HOSPITAL   (France)

^o HÔPITAL MICHALLON   (France)

^p POITIERS UNIVERSITY HOSPITAL   (France)

^q LAPEYRONIE HOSPITAL   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ETOMIDATE; FLUDROCORTISONE; HYDROCORTISONE; PLACEBO; TETRACOSACTIDE; NONSTEROID ANTIINFLAMMATORY AGENT;

ABSENCE OF SIDE EFFECTS; ADOLESCENT; ADRENAL FUNCTION; ADRENAL INSUFFICIENCY; ADULT; AGED; ARTICLE; ARTIFICIAL VENTILATION; CHRONIC DISEASE; COMPUTER ASSISTED TOMOGRAPHY; CONTINUOUS INFUSION; CONTROLLED STUDY; CORTICOTROPIN TEST; CRANIECTOMY; DISEASE ASSOCIATION; DOUBLE BLIND PROCEDURE; DRUG ADMINISTRATION ROUTE; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG WITHDRAWAL; ENTERAL DRUG ADMINISTRATION; EXPLORATORY RESEARCH; FEMALE; FOLLOW UP; FRANCE; GLASGOW COMA SCALE; HAZARD RATIO; HOSPITAL ACQUIRED PNEUMONIA; HOSPITALIZATION; HUMAN; INCIDENCE; INFECTION; INTENSIVE CARE; INTENTION TO TREAT ANALYSIS; LEUKOCYTOSIS; LEUKOPENIA; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MECHAISM GLASGOW COMA SCALE AGE ARTERIAL PRESSURE SCORE; MULTICENTER STUDY; OSMOTHERAPY; PHASE 3 CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SCORING SYSTEM; THORAX RADIOGRAPHY; TRADITIONAL MEDICINE; TRAUMATIC BRAIN INJURY; TREATMENT DURATION; TREATMENT INDICATION; BLOOD; BRAIN INJURY; CLINICAL TRIAL; COMPLICATION; INTENSIVE CARE UNIT; MIDDLE AGED; PNEUMONIA, VENTILATOR-ASSOCIATED; YOUNG ADULT;

ADOLESCENT; ADRENAL INSUFFICIENCY; ADULT; AGED; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BRAIN INJURIES; DOUBLE-BLIND METHOD; FEMALE; FLUDROCORTISONE; HUMANS; HYDROCORTISONE; INTENSIVE CARE UNITS; INTENTION TO TREAT ANALYSIS; MALE; MIDDLE AGED; PNEUMONIA, VENTILATOR-ASSOCIATED; YOUNG ADULT;

EID: 84908066607     PISSN: 22132600     EISSN: 22132619     Source Type: Journal    
DOI: 10.1016/S2213-2600(14)70144-4     Document Type: Article

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