LncRNA-ATB mediated E-cadherin repression promotes the progression of colon cancer and predicts poor prognosis

Journal of Gastroenterology and Hepatology (Australia)

Volumn 31, Issue 3, 2016, Pages 595-603

  Yue, Ben ^a   Qiu, Shenglong ^a   Zhao, Senlin ^a   Liu, Chenchen ^a   Zhang, Dongyuan ^a   Yu, Fudong ^a   Peng, Zhihai ^a   Yan, Dongwang ^a  

^a SHANGHAI FIRST PEOPLE S HOSPITAL   (China)

Author keywords

Colon cancer; E cadherin; LncRNA ATB; Oncogene; TGF

Indexed keywords

LONG UNTRANSLATED RNA; NERVE CELL ADHESION MOLECULE; TRANSFORMING GROWTH FACTOR BETA; UVOMORULIN; CADHERIN;

ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; CANCER GROWTH; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CELL DIFFERENTIATION; CELL PROLIFERATION ASSAY; COLON CANCER; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FEMALE; GENE EXPRESSION; HUMAN; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; CARCINOGENESIS; COLONIC NEOPLASMS; DISEASE COURSE; DOWN REGULATION; GENETICS; METABOLISM; METASTASIS; MOLECULARLY TARGETED THERAPY; MORTALITY; PATHOLOGY; PHYSIOLOGY; PROGNOSIS; SURVIVAL RATE; TUMOR INVASION;

CADHERINS; CARCINOGENESIS; COLONIC NEOPLASMS; DISEASE PROGRESSION; DOWN-REGULATION; FEMALE; GENE EXPRESSION; HUMANS; MALE; MOLECULAR TARGETED THERAPY; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM STAGING; PROGNOSIS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, LONG NONCODING; SURVIVAL RATE; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 84959115730     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/jgh.13206     Document Type: Article

References (37)

1. Ferlay J, Shin HR, Bray F et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int. J. Cancer 2010; 127: 2893-917.
2. Sieqel R, Desantis C, Jemal A. Colorectal cancer statistics, 2014. CA Cancer J. Clin. 2014; 64: 104-17.
3. Edwards BK, Ward E, Kohler BA et al. Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates. Cancer 2010; 116: 544-73.
4. Wapinski O, Chang HY. Long noncoding RNAs and human disease. Trends Cell Biol. 2011; 21: 354-61.
5. Khalil AM, Guttman M, Huarte M et al. Many human large intergenic noncoding RNAs associate with chromatin modifying complexes and affect gene expression. Proc. Natl. Acad. Sci. U. S. A. 2009; 106: 11667-72.
6. Guttman M, Rinn JL. Modular regulatory principles of large non-coding RNAs. Nature 2012; 482: 339-46.
7. Shao Y, Chen H, Jiang X et al. Low expression of lncRNA-HmlincRNA717 in human gastric cancer and its clinical significances. Tumor Biol. 2014; 35: 9591-5.
8. Li J, Chen Z, Tian L et al. LncRNA profile study reveals a three-lncRNA signature associated with the survival of patients with oesophageal squamous cell carcinoma. Gut 2014; 63: 1700-10.
9. Wang CY, Hua L, Yao KH et al. Long non-coding RNA CCAT2 is up-regulated in gastric cancer and associated with poor prognosis. Int. J. Clin. Exp. Pathol. 2015; 8: 779-85.
10. Ye Z, Zhou M, Tian B et al. Expression of lncRNA-CCAT1, E-cadherin and N-cadherin in colorectal cancer and its clinical significance. Int J Clin Exp Med. 2015; 8: 3707-15.
11. Ling H, Spizzo R, Atlasi Y et al. CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer. Genome Res. 2013; 23: 1446-61.
12. Yuan JH, Yang F, Wang F et al. A long noncoding RNA activated by TGF-β promotes the invasion-metastasis cascade in hepatocellular carcinoma. Cancer Cell 2014; 25: 666-81.
13. Kallen AN, Zhou XB, Xu J et al. The imprinted H19 lncRNA antagonizes let-7 microRNAs. Mol. Cell 2013; 52: 101-12.
14. Salmena L, Poliseno L, Tay Y et al. A ceRNA hypothesis: the Rosetta stone of a hidden RNA language? Cell 2011; 146: 353-8.
15. Wang J, Liu X, Wu H et al. CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer. Nucleic Acids Res. 2010; 38: 5366-83.
16. Iguchi T, Uchi R, Nambara S et al. A long noncoding RNA, lncRNA-ATB, is involved in the progression and prognosis of colorectal cancer. Anticancer Res 2015; 35: 1385-8.
17. Shao Y, Ye M, Jiang X et al. Gastric juice long noncoding RNA used as a tumor marker for screening gastric cancer. Cancer 2014; 120: 3320-8.
18. Tong YS, Wang XW, Zhou XL et al. Identification of the long non-coding RNA POU3F3 in plasma as a novel biomarker for diagnosis of esophageal squamous cell carcinoma. Mol. Cancer 2015; 14: 3.
19. Liu X, Yu J, Jiang L et al. MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1 (MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cell carcinoma cell lines. Cancer Genomics Proteomics 2009; 6: 131-9.
20. Xu TP, Huang MD, Xia R et al. Decreased expression of the long non-coding RNA FENDRR is associated with poor prognosis in gastric cancer and FENDRR regulates gastric cancer cell metastasis by affecting fibronectin1 expression. J. Hematol. Oncol. 2014; 7: 63.
21. Li Z, Zhao X, Liu Y et al. The long non-coding RNA HOTTIP promotes progression and gemcitabine resistance by regulating HOXA13 in pancreatic cancer. J. Transl. Med. 2015; 13: 442.
22. Wu ZH, Wang XL, Tang HM et al. Long non-coding RNA HOTAIR is a powerful predictor of metastasis and poor prognosis and is associated with epithelial-mesenchymal transition in colon cancer. Oncol. Rep. 2014; 32: 395-402.
23. Zhang EB, Yin DD, Sun M et al. P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression. Cell Death Dis. 2014; 5: e1234.
24. Jiang S, Wang HL, Yang J. Low expression of long non-coding RNA LET inhibits carcinogenesis of cervical cancer. Int. J. Clin. Exp. Pathol. 2015; 8: 806-11.
25. Ma MZ, Chu BF, Zhang Y et al. Long non-coding RNA CCAT 1 promotes gallbladder cancer development via negative modulation of miRNA-218-5p. Cell Death Dis. 2015; 6: e1583.
26. Jiang W, Zhang D, Wu Z et al. Long non-coding RNA BANCR promotes proliferation and migration of lung carcinoma via MAPK pathways. Biomed. Pharmacother. 2015; 69: 90-5.
27. Liu Q, Huang J, Zhou N et al. LncRNA loc285194 is a p53-regulated tumor suppressor. Nucleic Acids Res. 2013; 41: 4976-87.
28. Vleminckx K, Vakaet L Jr, Mareel M et al. Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 1991; 66: 101-19.
29. Birchmeier W, Behrens J. Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness. Biochim. Biophys. Acta 1994; 1198: 11-26.
30. Loboda A, Nebozhyn MV, Watters JW et al. EMT is the dominant program in human colon cancer. BMC Med. Genomics 2011; 4: 9.
31. Aqqarwal A, Prinz-Wohlqenannt M, Gröschel C et al. The calcium-sensing receptor suppresses epithelial-to-mesenchymal transition and stem cell-like phenotype in the colon. Mol. Cancer 2015; 14: 61.
32. Yang P, Li QJ, Feng Y et al. TGF-β-miR-34a-CCL22 signaling-induced Treg cell recruitment promotes venous metastases of HBV-positive hepatocellular carcinoma. Cancer Cell 2012; 22: 291-303.
33. Foltran L, Maglio GD, Pella N et al. Prognostic role of KRAS, NRAS, BRAF and PIK3CA mutations in advanced colorectal cancer. Future Oncol. 2015; 11: 629-40.
34. Jiang Y, Zhang C, Chen K et al. The clinical significance of DC-SIGN and DC-SIGNR, which are novel markers expressed in human colon cancer. Plos One. 2014; 9: e114748.
35. Han Y, Yang YN, Yuan HH et al. UCA1, a long non-coding RNA up-regulated in colorectal cancer influences cell proliferation, apoptosis and cell cycle distribution. Pathology 2014; 46: 396-401.
36. Liu Z, Shao Y, Tan L et al. Clinical significance of the low expression of FER1L4 in gastric cancer patients. Tumour Biol. 2014; 35: 9613-7.
37. Plieskatt J, Rinaldi G, Feng Y et al. A microRNA profile associated with opisthorchis viverrini-induced cholangiocarcinoma in tissue and plasma. BMC Cancer 2015; 15: 309.