The long non-coding RNA HOTTIP promotes progression and gemcitabine resistance by regulating HOXA13 in pancreatic cancer

Journal of Translational Medicine

Volumn 13, Issue 1, 2015, Pages

  Li, Zhihua ^a   Zhao, Xiaohui ^a   Zhou, Yu ^a   Liu, Yimin ^b   Zhou, Quanbo ^a   Ye, Huilin ^a   Wang, YinXue ^a   Zeng, Jinlong ^a   Song, Yadong ^a   Gao, Wenchao ^a   Zheng, ShangYou ^a   Zhuang, Baoxiong ^a   Chen, Huimou ^a   Li, Wenzhu ^a   Li, Haigang ^a   Li, Haifeng ^a   Fu, Zhiqiang ^a   Chen, Rufu ^a,b  

^a SUN YAT SEN UNIVERSITY   (China)

^b SUN YAT SEN MEMORIAL HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

Author keywords

Chemoresistance; Epithelial mesenchymal transition; HOTTIP; Oncogenic; Pancreatic cancer

Indexed keywords

BIOLOGICAL MARKER; GEMCITABINE; HOTTIP; LONG NON CODING RNA HOXA TRANSCRIPT AT THE DISTAL TIP; LONG UNTRANSLATED RNA; MESSENGER RNA; UNCLASSIFIED DRUG; DEOXYCYTIDINE; HOMEOBOX PROTEIN HOXA13; HOMEODOMAIN PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER GROWTH; CANCER RESISTANCE; CANCER TISSUE; CELL CYCLE PROGRESSION; CELL INVASION; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; DRUG SENSITIZATION; DRUG TARGETING; EPITHELIAL MESENCHYMAL TRANSITION; GENE CONTROL; GENE SILENCING; HIGH THROUGHPUT SEQUENCING; HISTOPATHOLOGY; HOXA13 GENE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LYMPH NODE METASTASIS; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUDE MOUSE; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PANCREAS CANCER; PANCREAS DUCT; PANCREATIC CANCER CELL LINE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR PROMOTION; TUMOR XENOGRAFT; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; BAGG ALBINO MOUSE; CELL CYCLE; DISEASE COURSE; DRUG EFFECTS; DRUG RESISTANCE; FEMALE; MALE; METABOLISM; MIDDLE AGED; PANCREAS TUMOR; PATHOLOGY; SURVIVAL ANALYSIS; TUMOR CELL LINE; TUMOR INVASION;

ANIMALS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; DEOXYCYTIDINE; DISEASE PROGRESSION; DRUG RESISTANCE, NEOPLASM; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE KNOCKDOWN TECHNIQUES; HOMEODOMAIN PROTEINS; HUMANS; MALE; MICE, INBRED BALB C; MICE, NUDE; MIDDLE AGED; NEOPLASM INVASIVENESS; PANCREATIC NEOPLASMS; RNA, LONG NONCODING; SURVIVAL ANALYSIS;

EID: 84925305152     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/s12967-015-0442-z     Document Type: Article

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