UCA1, a long non-coding RNA up-regulated in colorectal cancer influences cell proliferation, apoptosis and cell cycle distribution

Pathology

Volumn 46, Issue 5, 2014, Pages 396-401

  Han, Yu ^a   Yang, Ying Nan ^a   Yuan, Heng Heng ^a   Zhang, Ting Ting ^a   Sui, Hong ^a   Wei, Xiao Li ^a   Liu, Lei ^a   Huang, Peng ^a   Zhang, Wen Jie ^a   Bai, Yu Xian ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Colorectal cancer; Function; Long non coding RNAs; UCA1

Indexed keywords

LONG UNTRANSLATED RNA; UCA1 RNA, HUMAN;

AGED; APOPTOSIS; BIOSYNTHESIS; CELL CYCLE; CELL MOTION; CELL PROLIFERATION; COLORECTAL TUMOR; FEMALE; GENETICS; HUMAN; MALE; MIDDLE AGED; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

AGED; APOPTOSIS; CELL CYCLE; CELL MOVEMENT; CELL PROLIFERATION; COLORECTAL NEOPLASMS; FEMALE; HUMANS; MALE; MIDDLE AGED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, LONG NONCODING; UP-REGULATION;

EID: 84906809916     PISSN: 00313025     EISSN: 14653931     Source Type: Journal    
DOI: 10.1097/PAT.0000000000000125     Document Type: Article

References (21)

1. Jemal A, Bray F, Center MM, et al. Global cancer statistics. CA Cancer J Clin 2011; 61: 69-90.
2. Ponting CP, Belgard TG. Transcribed dark matter: meaning or myth? Hum Mol Genet 2010; 19: R162-8.
3. Ponting CP, Oliver PL, ReikW. Evolution and functions of long noncoding RNAs. Cell 2009; 136: 629-41.
4. Chen LL, Carmichael GG. Decoding the function of nuclear long noncoding RNAs. Curr Opin Cell Biol 2010; 22: 357-64.
5. Rinn JL, Chang HY. Genome regulation by long noncoding RNAs. Annu Rev Biochem 2012; 81: 145-66.
6. Li X, Wu Z, Fu X, et al. Long noncoding RNAs: insights from biological features and functions to diseases. Med Res Rev 2013; 33: 517-53.
7. Faust T, Frankel A, D'Orso I. Transcription control by long non-coding RNAs. Transcription 2012; 3: 78-86.
8. Gong C, Maquat LE. lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 30 UTRs via Alu elements. Nature 2011; 470: 284-8.
9. Huarte M, Rinn JL. Large non-coding RNAs: missing links in cancer? Hum Mol Genet 2010; 19: R152-61.
10. Reis EM, Verjovski-Almeida S. Perspectives of long non-coding RNAs in cancer diagnostics. Front Genet 2012; 3: 32.
11. Gibb EA, Brown CJ, LamWL. The functional role of long non-coding RNA in human carcinomas. Mol Cancer 2011; 10: 38.
12. Spizzo R, Almeida MI, Colombatti A, et al. Long non-coding RNAs and cancer: a new frontier of translational research? Oncogene 2012; 31: 4577-87.
13. Prensner JR, Chinnaiyan AM. The emergence of lncRNAs in cancer biology. Cancer Discov 2011; 1: 391-407.
14. Qi P, Du X. The long non-coding RNAs, a new cancer diagnostic and therapeutic gold mine. Mod Pathol 2013; 26: 155-65.
15. Wang F, Li X, Xie X, et al. UCA1, a non-protein-coding RNA up-regulated in bladder carcinoma and embryo, influencing cell growth and promoting invasion. FEBS Lett 2008; 582: 1919-27.
16. Wang XS, Zhang Z,Wang HC, et al. Rapid identification of UCA1 as a very sensitive and specific unique marker for human bladder carcinoma. Clin Cancer Res 2006; 12: 4851-8.
17. Tsang WP, Wong TW, Cheung AH, et al. Induction of drug resistance and transformation in human cancer cells by the noncoding RNA CUDR. RNA 2007; 13: 890-8.
18. Sobin LH,Wittekind C. TNM Classification of Malignant Tumours. 6th ed. New York: Wiley, 2002; 131-141.
19. Qi P, Xu MD, Ni SJ, et al. Low expression of LOC285194 is associated with poor prognosis in colorectal cancer. J Transl Med 2013; 11: 122.
20. Wang Y, Chen W, Yang C, et al. Long non-coding RNA UCA1a(CUDR) promotes proliferation and tumorigenesis of bladder cancer. Int J Oncol 2012; 41: 276-84.
21. Yang C, Li X, Wang Y, et al. Long non-coding RNA UCA1 regulated cell cycle distribution via CREB through PI3-K dependent pathway in bladder carcinoma cells. Gene 2012; 496: 8-16.