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Volumn 65, Issue 6, 2015, Pages 283-291

Systemic effects of periodontitis: Lessons learned from research on atherosclerotic vascular disease and adverse pregnancy outcomes

Author keywords

cardiovascular; gestation; Inflammation; periodontal; review; therapy

Indexed keywords

AUTACOID;

EID: 84959101995     PISSN: 00206539     EISSN: 1875595X     Source Type: Journal    
DOI: 10.1111/idj.12185     Document Type: Review
Times cited : (80)

References (83)
  • 1
    • 0024511197 scopus 로고
    • Association between dental health and acute myocardial infarction
    • Mattila KJ, Nieminen MS, Valtonen VV, et al,. Association between dental health and acute myocardial infarction. BMJ 1989 298: 779-781.
    • (1989) BMJ , vol.298 , pp. 779-781
    • Mattila, K.J.1    Nieminen, M.S.2    Valtonen, V.V.3
  • 2
    • 0030256677 scopus 로고    scopus 로고
    • Periodontal infection as a possible risk factor for preterm low birth weight
    • Offenbacher S, Katz V, Fertik G, et al,. Periodontal infection as a possible risk factor for preterm low birth weight. J Periodontol 1996 67 (10 Suppl): 1103-1113.
    • (1996) J Periodontol , vol.67 , Issue.10 , pp. 1103-1113
    • Offenbacher, S.1    Katz, V.2    Fertik, G.3
  • 3
    • 77953616099 scopus 로고    scopus 로고
    • Periodontitis: A polymicrobial disruption of host homeostasis
    • Darveau RP,. Periodontitis: a polymicrobial disruption of host homeostasis. Nat Rev Microbiol 2010 8: 481-490.
    • (2010) Nat Rev Microbiol , vol.8 , pp. 481-490
    • Darveau, R.P.1
  • 4
    • 84866507629 scopus 로고    scopus 로고
    • Prevalence of periodontitis in adults in the United States: 2009 and 2010
    • Eke PI, Dye BA, Wei L, et al,. Prevalence of periodontitis in adults in the United States: 2009 and 2010. J Dent Res 2012 91: 914-920.
    • (2012) J Dent Res , vol.91 , pp. 914-920
    • Eke, P.I.1    Dye, B.A.2    Wei, L.3
  • 5
    • 84910049225 scopus 로고    scopus 로고
    • Global burden of severe periodontitis in 1990-2010: A systematic review and meta-regression
    • Kassebaum NJ, Bernabe E, Dahiya M, et al,. Global burden of severe periodontitis in 1990-2010: a systematic review and meta-regression. J Dent Res 2014 93: 1045-1053.
    • (2014) J Dent Res , vol.93 , pp. 1045-1053
    • Kassebaum, N.J.1    Bernabe, E.2    Dahiya, M.3
  • 6
    • 84908022153 scopus 로고    scopus 로고
    • Periodontal microbiology-the lid's off the box again
    • Curtis MA,. Periodontal microbiology-the lid's off the box again. J Dent Res 2014 93: 840-842.
    • (2014) J Dent Res , vol.93 , pp. 840-842
    • Curtis, M.A.1
  • 7
    • 0035261313 scopus 로고    scopus 로고
    • The dentogingival epithelial surface area revisited
    • Hujoel PP, White BA, Garcia RI, et al,. The dentogingival epithelial surface area revisited. J Periodontal Res 2001 36: 48-55.
    • (2001) J Periodontal Res , vol.36 , pp. 48-55
    • Hujoel, P.P.1    White, B.A.2    Garcia, R.I.3
  • 8
    • 0028457301 scopus 로고
    • The protective nature of host responses in periodontal diseases
    • Ebersole JL, Taubman MA,. The protective nature of host responses in periodontal diseases. Periodontol 2000 1994 5: 112-141.
    • (1994) Periodontol 2000 , vol.5 , pp. 112-141
    • Ebersole, J.L.1    Taubman, M.A.2
  • 11
    • 0025046814 scopus 로고
    • Detection and quantitation by lysis-filtration of bacteremia after different oral surgical procedures
    • Heimdahl A, Hall G, Hedberg M, et al,. Detection and quantitation by lysis-filtration of bacteremia after different oral surgical procedures. J Clin Microbiol 1990 28: 2205-2209.
    • (1990) J Clin Microbiol , vol.28 , pp. 2205-2209
    • Heimdahl, A.1    Hall, G.2    Hedberg, M.3
  • 12
    • 48249085439 scopus 로고    scopus 로고
    • Bacteremia associated with toothbrushing and dental extraction
    • Lockhart PB, Brennan MT, Sasser HC, et al,. Bacteremia associated with toothbrushing and dental extraction. Circulation 2008 117: 3118-3125.
    • (2008) Circulation , vol.117 , pp. 3118-3125
    • Lockhart, P.B.1    Brennan, M.T.2    Sasser, H.C.3
  • 13
    • 0032062299 scopus 로고    scopus 로고
    • Inflammatory mediators of the terminal dentition in adult and early onset periodontitis
    • Salvi GE, Brown CE, Fujihashi K, et al,. Inflammatory mediators of the terminal dentition in adult and early onset periodontitis. J Periodontal Res 1998 33: 212-225.
    • (1998) J Periodontal Res , vol.33 , pp. 212-225
    • Salvi, G.E.1    Brown, C.E.2    Fujihashi, K.3
  • 14
    • 77955761243 scopus 로고    scopus 로고
    • Human gingiva is another site of C-reactive protein formation
    • Lu Q, Jin L,. Human gingiva is another site of C-reactive protein formation. J Clin Periodontol 2010 37: 789-796.
    • (2010) J Clin Periodontol , vol.37 , pp. 789-796
    • Lu, Q.1    Jin, L.2
  • 15
    • 0037469177 scopus 로고    scopus 로고
    • Clinical application of C-reactive protein for cardiovascular disease detection and prevention
    • Ridker PM,. Clinical application of C-reactive protein for cardiovascular disease detection and prevention. Circulation 2003 107: 363-369.
    • (2003) Circulation , vol.107 , pp. 363-369
    • Ridker, P.M.1
  • 16
    • 77956022026 scopus 로고    scopus 로고
    • "gum bug, leave my heart alone!"-epidemiologic and mechanistic evidence linking periodontal infections and atherosclerosis
    • Kebschull M, Demmer RT, Papapanou PN,. "Gum bug, leave my heart alone!"-epidemiologic and mechanistic evidence linking periodontal infections and atherosclerosis. J Dent Res 2010 89: 879-902.
    • (2010) J Dent Res , vol.89 , pp. 879-902
    • Kebschull, M.1    Demmer, R.T.2    Papapanou, P.N.3
  • 17
    • 84959167560 scopus 로고    scopus 로고
    • Effects of periodontal diseases on general health
    • Lindhe J. Lang N.P. editors. 6th edn. Chichester, West Sussex, UK: Wiley
    • Papapanou PN, Lalla E,. Effects of periodontal diseases on general health. In:, Lindhe J, Lang NP, editors. Clinical Periodontology and Implant Dentistry, Vol. 1. 6th edn. Chichester, West Sussex, UK: Wiley; 2015. p. 437-462.
    • (2015) Clinical Periodontology and Implant Dentistry , vol.1 , pp. 437-462
    • Papapanou, P.N.1    Lalla, E.2
  • 18
    • 0034089572 scopus 로고    scopus 로고
    • Infection and atherosclerosis: Potential roles of pathogen burden and molecular mimicry
    • Epstein SE, Zhu J, Burnett MS, et al,. Infection and atherosclerosis: potential roles of pathogen burden and molecular mimicry. Arterioscler Thromb Vasc Biol 2000 20: 1417-1420.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1417-1420
    • Epstein, S.E.1    Zhu, J.2    Burnett, M.S.3
  • 19
    • 0042490523 scopus 로고    scopus 로고
    • Oral infection with a periodontal pathogen accelerates early atherosclerosis in apolipoprotein E-null mice
    • Lalla E, Lamster IB, Hofmann MA, et al,. Oral infection with a periodontal pathogen accelerates early atherosclerosis in apolipoprotein E-null mice. Arterioscler Thromb Vasc Biol 2003 23: 1405-1411.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1405-1411
    • Lalla, E.1    Lamster, I.B.2    Hofmann, M.A.3
  • 20
    • 0034305658 scopus 로고    scopus 로고
    • Identification of periodontal pathogens in atheromatous plaques
    • Haraszthy VI, Zambon JJ, Trevisan M, et al,. Identification of periodontal pathogens in atheromatous plaques. J Periodontol 2000 71: 1554-1560.
    • (2000) J Periodontol , vol.71 , pp. 1554-1560
    • Haraszthy, V.I.1    Zambon, J.J.2    Trevisan, M.3
  • 21
    • 23944471031 scopus 로고    scopus 로고
    • Human atherosclerotic plaque contains viable invasive Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis
    • Kozarov EV, Dorn BR, Shelburne CE, et al,. Human atherosclerotic plaque contains viable invasive Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis. Arterioscler Thromb Vasc Biol 2005 25: e17-e18.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. e17-e18
    • Kozarov, E.V.1    Dorn, B.R.2    Shelburne, C.E.3
  • 24
    • 0024552844 scopus 로고
    • Evaluation of a risk-scoring system for prediction of preterm labor
    • Holbrook RH Jr, Laros RK Jr, Creasy RK,. Evaluation of a risk-scoring system for prediction of preterm labor. Am J Perinatol 1989 6: 62-68.
    • (1989) Am J Perinatol , vol.6 , pp. 62-68
    • Holbrook, R.H.1    Laros, R.K.2    Creasy, R.K.3
  • 26
    • 0032111021 scopus 로고    scopus 로고
    • Preterm birth: Associations with genital and possibly oral microflora
    • Hill GB,. Preterm birth: associations with genital and possibly oral microflora. Ann Periodontol 1998 3: 222-232.
    • (1998) Ann Periodontol , vol.3 , pp. 222-232
    • Hill, G.B.1
  • 27
    • 33645935083 scopus 로고    scopus 로고
    • Transmission of an uncultivated Bergeyella strain from the oral cavity to amniotic fluid in a case of preterm birth
    • Han YW, Ikegami A, Bissada NF, et al,. Transmission of an uncultivated Bergeyella strain from the oral cavity to amniotic fluid in a case of preterm birth. J Clin Microbiol 2006 44: 1475-1483.
    • (2006) J Clin Microbiol , vol.44 , pp. 1475-1483
    • Han, Y.W.1    Ikegami, A.2    Bissada, N.F.3
  • 28
    • 0028107968 scopus 로고
    • Effects of Escherichia coli and Porphyromonas gingivalis lipopolysaccharide on pregnancy outcome in the golden hamster
    • Collins JG, Smith MA, Arnold RR, et al,. Effects of Escherichia coli and Porphyromonas gingivalis lipopolysaccharide on pregnancy outcome in the golden hamster. Infect Immun 1994 62: 4652-4655.
    • (1994) Infect Immun , vol.62 , pp. 4652-4655
    • Collins, J.G.1    Smith, M.A.2    Arnold, R.R.3
  • 29
    • 0027998538 scopus 로고
    • Effects of a Porphyromonas gingivalis infection on inflammatory mediator response and pregnancy outcome in hamsters
    • Collins JG, Windley HW 3rd, Arnold RR, et al,. Effects of a Porphyromonas gingivalis infection on inflammatory mediator response and pregnancy outcome in hamsters. Infect Immun 1994 62: 4356-4361.
    • (1994) Infect Immun , vol.62 , pp. 4356-4361
    • Collins, J.G.1    Windley, H.W.2    Arnold, R.R.3
  • 30
    • 1842431570 scopus 로고    scopus 로고
    • Fusobacterium nucleatum induces premature and term stillbirths in pregnant mice: Implication of oral bacteria in preterm birth
    • Han YW, Redline RW, Li M, et al,. Fusobacterium nucleatum induces premature and term stillbirths in pregnant mice: implication of oral bacteria in preterm birth. Infect Immun 2004 72: 2272-2279.
    • (2004) Infect Immun , vol.72 , pp. 2272-2279
    • Han, Y.W.1    Redline, R.W.2    Li, M.3
  • 31
    • 13444291639 scopus 로고    scopus 로고
    • Chronic maternal and fetal Porphyromonas gingivalis exposure during pregnancy in rabbits
    • Boggess KA, Madianos PN, Preisser JS, et al,. Chronic maternal and fetal Porphyromonas gingivalis exposure during pregnancy in rabbits. Am J Obstet Gynecol 2005 192: 554-557.
    • (2005) Am J Obstet Gynecol , vol.192 , pp. 554-557
    • Boggess, K.A.1    Madianos, P.N.2    Preisser, J.S.3
  • 32
    • 0031014624 scopus 로고    scopus 로고
    • Systemic acute-phase reactants, C-reactive protein and haptoglobin, in adult periodontitis
    • Ebersole JL, Machen RL, Steffen MJ, et al,. Systemic acute-phase reactants, C-reactive protein and haptoglobin, in adult periodontitis. Clin Exp Immunol 1997 107: 347-352.
    • (1997) Clin Exp Immunol , vol.107 , pp. 347-352
    • Ebersole, J.L.1    Machen, R.L.2    Steffen, M.J.3
  • 33
    • 0034438347 scopus 로고    scopus 로고
    • Acute-phase inflammatory response to periodontal disease in the US population
    • Slade GD, Offenbacher S, Beck JD, et al,. Acute-phase inflammatory response to periodontal disease in the US population. J Dent Res 2000 79: 49-57.
    • (2000) J Dent Res , vol.79 , pp. 49-57
    • Slade, G.D.1    Offenbacher, S.2    Beck, J.D.3
  • 34
    • 0034304221 scopus 로고    scopus 로고
    • Elevation of systemic markers related to cardiovascular diseases in the peripheral blood of periodontitis patients
    • Loos BG, Craandijk J, Hoek FJ, et al,. Elevation of systemic markers related to cardiovascular diseases in the peripheral blood of periodontitis patients. J Periodontol 2000 71: 1528-1534.
    • (2000) J Periodontol , vol.71 , pp. 1528-1534
    • Loos, B.G.1    Craandijk, J.2    Hoek, F.J.3
  • 35
    • 0034141139 scopus 로고    scopus 로고
    • Examination of the relation between periodontal health status and cardiovascular risk factors: Serum total and high density lipoprotein cholesterol, C-reactive protein, and plasma fibrinogen
    • Wu T, Trevisan M, Genco RJ, et al,. Examination of the relation between periodontal health status and cardiovascular risk factors: serum total and high density lipoprotein cholesterol, C-reactive protein, and plasma fibrinogen. Am J Epidemiol 2000 151: 273-282.
    • (2000) Am J Epidemiol , vol.151 , pp. 273-282
    • Wu, T.1    Trevisan, M.2    Genco, R.J.3
  • 36
    • 4444306348 scopus 로고    scopus 로고
    • Periodontal disease, but not edentulism, is independently associated with increased plasma fibrinogen levels. Results from a population-based study
    • Schwahn C, Volzke H, Robinson DM, et al,. Periodontal disease, but not edentulism, is independently associated with increased plasma fibrinogen levels. Results from a population-based study. Thromb Haemost 2004 92: 244-252.
    • (2004) Thromb Haemost , vol.92 , pp. 244-252
    • Schwahn, C.1    Volzke, H.2    Robinson, D.M.3
  • 37
    • 40849088226 scopus 로고    scopus 로고
    • A systematic review and meta-analyses on C-reactive protein in relation to periodontitis
    • Paraskevas S, Huizinga JD, Loos BG,. A systematic review and meta-analyses on C-reactive protein in relation to periodontitis. J Clin Periodontol 2008 35: 277-290.
    • (2008) J Clin Periodontol , vol.35 , pp. 277-290
    • Paraskevas, S.1    Huizinga, J.D.2    Loos, B.G.3
  • 38
    • 0033531215 scopus 로고    scopus 로고
    • Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group
    • O'Leary DH, Polak JF, Kronmal RA, et al,. Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group. N Engl J Med 1999 340: 14-22.
    • (1999) N Engl J Med , vol.340 , pp. 14-22
    • O'Leary, D.H.1    Polak, J.F.2    Kronmal, R.A.3
  • 39
    • 0035571671 scopus 로고    scopus 로고
    • Relationship of periodontal disease to carotid artery intima-media wall thickness: The Atherosclerosis Risk in Communities (ARIC) Study
    • Beck JD, Elter JR, Heiss G, et al,. Relationship of periodontal disease to carotid artery intima-media wall thickness: the Atherosclerosis Risk in Communities (ARIC) Study. Arterioscler Thromb Vasc Biol 2001 21: 1816-1822.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1816-1822
    • Beck, J.D.1    Elter, J.R.2    Heiss, G.3
  • 40
    • 13444265872 scopus 로고    scopus 로고
    • Periodontal microbiota and carotid intima-media thickness: The Oral Infections and Vascular Disease Epidemiology Study (INVEST)
    • Desvarieux M, Demmer RT, Rundek T, et al,. Periodontal microbiota and carotid intima-media thickness: the Oral Infections and Vascular Disease Epidemiology Study (INVEST). Circulation 2005 111: 576-582.
    • (2005) Circulation , vol.111 , pp. 576-582
    • Desvarieux, M.1    Demmer, R.T.2    Rundek, T.3
  • 41
    • 77954385584 scopus 로고    scopus 로고
    • Periodontal bacteria and hypertension: The oral infections and vascular disease epidemiology study (INVEST)
    • Desvarieux M, Demmer RT, Jacobs DR Jr, et al,. Periodontal bacteria and hypertension: the oral infections and vascular disease epidemiology study (INVEST). J Hypertens 2010 28: 1413-1421.
    • (2010) J Hypertens , vol.28 , pp. 1413-1421
    • Desvarieux, M.1    Demmer, R.T.2    Jacobs, D.R.3
  • 42
    • 27644594656 scopus 로고    scopus 로고
    • Associations between IgG antibody to oral organisms and carotid intima-medial thickness in community-dwelling adults
    • Beck JD, Eke P, Lin D, et al,. Associations between IgG antibody to oral organisms and carotid intima-medial thickness in community-dwelling adults. Atherosclerosis 2005 183: 342-348.
    • (2005) Atherosclerosis , vol.183 , pp. 342-348
    • Beck, J.D.1    Eke, P.2    Lin, D.3
  • 43
    • 16244383257 scopus 로고    scopus 로고
    • Serum antibody levels to Actinobacillus actinomycetemcomitans predict the risk for coronary heart disease
    • Pussinen PJ, Nyyssonen K, Alfthan G, et al,. Serum antibody levels to Actinobacillus actinomycetemcomitans predict the risk for coronary heart disease. Arterioscler Thromb Vasc Biol 2005 25: 833-838.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 833-838
    • Pussinen, P.J.1    Nyyssonen, K.2    Alfthan, G.3
  • 44
    • 84898911288 scopus 로고    scopus 로고
    • Changes in clinical and microbiological periodontal profiles relate to progression of carotid intima-media thickness: The Oral Infections and Vascular Disease Epidemiology Study (INVEST)
    • Desvarieux M, Demmer RT, Rundek T, et al,. Changes in clinical and microbiological periodontal profiles relate to progression of carotid intima-media thickness: the Oral Infections and Vascular Disease Epidemiology Study (INVEST). J Am Heart Assoc 2013 2: e000254.
    • (2013) J Am Heart Assoc , vol.2 , pp. e000254
    • Desvarieux, M.1    Demmer, R.T.2    Rundek, T.3
  • 46
    • 37649023661 scopus 로고    scopus 로고
    • Markers of systemic bacterial exposure in periodontal disease and cardiovascular disease risk: A systematic review and meta-analysis
    • Mustapha IZ, Debrey S, Oladubu M, et al,. Markers of systemic bacterial exposure in periodontal disease and cardiovascular disease risk: a systematic review and meta-analysis. J Periodontol 2007 78: 2289-2302.
    • (2007) J Periodontol , vol.78 , pp. 2289-2302
    • Mustapha, I.Z.1    Debrey, S.2    Oladubu, M.3
  • 47
    • 57249094305 scopus 로고    scopus 로고
    • Periodontal disease and coronary heart disease incidence: A systematic review and meta-analysis
    • Humphrey LL, Fu R, Buckley DI, et al,. Periodontal disease and coronary heart disease incidence: a systematic review and meta-analysis. J Gen Intern Med 2008 23: 2079-2086.
    • (2008) J Gen Intern Med , vol.23 , pp. 2079-2086
    • Humphrey, L.L.1    Fu, R.2    Buckley, D.I.3
  • 48
    • 84861336354 scopus 로고    scopus 로고
    • Periodontal disease and atherosclerotic vascular disease: Does the evidence support an independent association?: A scientific statement from the American Heart Association
    • Lockhart PB, Bolger AF, Papapanou PN, et al,. Periodontal disease and atherosclerotic vascular disease: does the evidence support an independent association?: a scientific statement from the American Heart Association. Circulation 2012 125: 2520-2544.
    • (2012) Circulation , vol.125 , pp. 2520-2544
    • Lockhart, P.B.1    Bolger, A.F.2    Papapanou, P.N.3
  • 49
    • 84904980158 scopus 로고    scopus 로고
    • Periodontal disease and stroke: A meta-analysis of cohort studies
    • e66-e67
    • Lafon A, Pereira B, Dufour T, et al,. Periodontal disease and stroke: a meta-analysis of cohort studies. Eur J Neurol 2014 21: 1155-1161, e66-e67.
    • (2014) Eur J Neurol , vol.21 , pp. 1155-1161
    • Lafon, A.1    Pereira, B.2    Dufour, T.3
  • 50
    • 41649092003 scopus 로고    scopus 로고
    • Age-dependent associations between chronic periodontitis/edentulism and risk of coronary heart disease
    • Dietrich T, Jimenez M, Krall Kaye EA, et al,. Age-dependent associations between chronic periodontitis/edentulism and risk of coronary heart disease. Circulation 2008 117: 1668-1674.
    • (2008) Circulation , vol.117 , pp. 1668-1674
    • Dietrich, T.1    Jimenez, M.2    Krall Kaye, E.A.3
  • 51
    • 70449368665 scopus 로고    scopus 로고
    • Periodontitis and incidence of cerebrovascular disease in men
    • Jimenez M, Krall EA, Garcia RI, et al,. Periodontitis and incidence of cerebrovascular disease in men. Ann Neurol 2009 66: 505-512.
    • (2009) Ann Neurol , vol.66 , pp. 505-512
    • Jimenez, M.1    Krall, E.A.2    Garcia, R.I.3
  • 52
    • 34248674367 scopus 로고    scopus 로고
    • Systemic exposure to Porphyromonas gingivalis predicts incident stroke
    • Pussinen PJ, Alfthan G, Jousilahti P, et al,. Systemic exposure to Porphyromonas gingivalis predicts incident stroke. Atherosclerosis 2007 193: 222-228.
    • (2007) Atherosclerosis , vol.193 , pp. 222-228
    • Pussinen, P.J.1    Alfthan, G.2    Jousilahti, P.3
  • 53
    • 51249102986 scopus 로고    scopus 로고
    • Periodontitis and the risk for non-fatal stroke in Korean adults
    • Sim SJ, Kim HD, Moon JY, et al,. Periodontitis and the risk for non-fatal stroke in Korean adults. J Periodontol 2008 79: 1652-1658.
    • (2008) J Periodontol , vol.79 , pp. 1652-1658
    • Sim, S.J.1    Kim, H.D.2    Moon, J.Y.3
  • 54
    • 29644446378 scopus 로고    scopus 로고
    • Tooth loss and heart disease: Findings from the Behavioral Risk Factor Surveillance System
    • Okoro CA, Balluz LS, Eke PI, et al,. Tooth loss and heart disease: findings from the Behavioral Risk Factor Surveillance System. Am J Prev Med 2005 29 (5 Suppl 1): 50-56.
    • (2005) Am J Prev Med , vol.29 , Issue.5 , pp. 50-56
    • Okoro, C.A.1    Balluz, L.S.2    Eke, P.I.3
  • 55
    • 0036356019 scopus 로고    scopus 로고
    • Periodontitis-systemic disease associations in the presence of smoking-causal or coincidental?
    • Hujoel PP, Drangsholt M, Spiekerman C, et al,. Periodontitis-systemic disease associations in the presence of smoking-causal or coincidental? Periodontol 2000 2002 30: 51-60.
    • (2002) Periodontol 2000 , vol.30 , pp. 51-60
    • Hujoel, P.P.1    Drangsholt, M.2    Spiekerman, C.3
  • 56
    • 38549140265 scopus 로고    scopus 로고
    • The Periodontitis and Vascular Events (PAVE) pilot study: Adverse events
    • Beck JD, Couper DJ, Falkner KL, et al,. The Periodontitis and Vascular Events (PAVE) pilot study: adverse events. J Periodontol 2008 79: 90-96.
    • (2008) J Periodontol , vol.79 , pp. 90-96
    • Beck, J.D.1    Couper, D.J.2    Falkner, K.L.3
  • 57
    • 59649115024 scopus 로고    scopus 로고
    • Results from the Periodontitis and Vascular Events (PAVE) Study: A pilot multicentered, randomized, controlled trial to study effects of periodontal therapy in a secondary prevention model of cardiovascular disease
    • Offenbacher S, Beck JD, Moss K, et al,. Results from the Periodontitis and Vascular Events (PAVE) Study: a pilot multicentered, randomized, controlled trial to study effects of periodontal therapy in a secondary prevention model of cardiovascular disease. J Periodontol 2009 80: 190-201.
    • (2009) J Periodontol , vol.80 , pp. 190-201
    • Offenbacher, S.1    Beck, J.D.2    Moss, K.3
  • 58
    • 3242799584 scopus 로고    scopus 로고
    • Periodontal disease and C-reactive protein-associated cardiovascular risk
    • D'Aiuto F, Ready D, Tonetti MS,. Periodontal disease and C-reactive protein-associated cardiovascular risk. J Periodontal Res 2004 39: 236-241.
    • (2004) J Periodontal Res , vol.39 , pp. 236-241
    • D'Aiuto, F.1    Ready, D.2    Tonetti, M.S.3
  • 59
    • 16844376535 scopus 로고    scopus 로고
    • Short-term effects of intensive periodontal therapy on serum inflammatory markers and cholesterol
    • D'Aiuto F, Nibali L, Parkar M, et al,. Short-term effects of intensive periodontal therapy on serum inflammatory markers and cholesterol. J Dent Res 2005 84: 269-273.
    • (2005) J Dent Res , vol.84 , pp. 269-273
    • D'Aiuto, F.1    Nibali, L.2    Parkar, M.3
  • 60
    • 25144521674 scopus 로고    scopus 로고
    • Contribution of periodontal therapy on individual cardiovascular risk assessment
    • D'Aiuto F, Tonetti MS,. Contribution of periodontal therapy on individual cardiovascular risk assessment. Arch Intern Med 2005 165: 1920-1921.
    • (2005) Arch Intern Med , vol.165 , pp. 1920-1921
    • D'Aiuto, F.1    Tonetti, M.S.2
  • 61
    • 63049116222 scopus 로고    scopus 로고
    • Heterogeneity of systemic inflammatory responses to periodontal therapy
    • Behle JH, Sedaghatfar MH, Demmer RT, et al,. Heterogeneity of systemic inflammatory responses to periodontal therapy. J Clin Periodontol 2009 36: 287-294.
    • (2009) J Clin Periodontol , vol.36 , pp. 287-294
    • Behle, J.H.1    Sedaghatfar, M.H.2    Demmer, R.T.3
  • 62
    • 84885400384 scopus 로고    scopus 로고
    • The influence of anti-infective periodontal treatment on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
    • Demmer RT, Trinquart L, Zuk A, et al,. The influence of anti-infective periodontal treatment on C-reactive protein: a systematic review and meta-analysis of randomized controlled trials. PLoS ONE 2013 8: e77441.
    • (2013) PLoS ONE , vol.8 , pp. e77441
    • Demmer, R.T.1    Trinquart, L.2    Zuk, A.3
  • 63
    • 0242349760 scopus 로고    scopus 로고
    • Endothelial function testing as a biomarker of vascular disease
    • Verma S, Buchanan MR, Anderson TJ,. Endothelial function testing as a biomarker of vascular disease. Circulation 2003 108: 2054-2059.
    • (2003) Circulation , vol.108 , pp. 2054-2059
    • Verma, S.1    Buchanan, M.R.2    Anderson, T.J.3
  • 64
    • 13844312632 scopus 로고    scopus 로고
    • Endothelial dysfunction in patients with chronic periodontitis and its improvement after initial periodontal therapy
    • Mercanoglu F, Oflaz H, Oz O, et al,. Endothelial dysfunction in patients with chronic periodontitis and its improvement after initial periodontal therapy. J Periodontol 2004 75: 1694-1700.
    • (2004) J Periodontol , vol.75 , pp. 1694-1700
    • Mercanoglu, F.1    Oflaz, H.2    Oz, O.3
  • 65
    • 20544445209 scopus 로고    scopus 로고
    • Periodontal treatment improves endothelial dysfunction in patients with severe periodontitis
    • Seinost G, Wimmer G, Skerget M, et al,. Periodontal treatment improves endothelial dysfunction in patients with severe periodontitis. Am Heart J 2005 149: 1050-1054.
    • (2005) Am Heart J , vol.149 , pp. 1050-1054
    • Seinost, G.1    Wimmer, G.2    Skerget, M.3
  • 66
    • 29144432197 scopus 로고    scopus 로고
    • The effects of periodontal therapy on vascular endothelial function: A pilot trial
    • Elter JR, Hinderliter AL, Offenbacher S, et al,. The effects of periodontal therapy on vascular endothelial function: a pilot trial. Am Heart J 2006 151: 47.
    • (2006) Am Heart J , vol.151 , pp. 47
    • Elter, J.R.1    Hinderliter, A.L.2    Offenbacher, S.3
  • 67
    • 33847346939 scopus 로고    scopus 로고
    • Treatment of periodontitis and endothelial function
    • Tonetti MS, D'Aiuto F, Nibali L, et al,. Treatment of periodontitis and endothelial function. N Engl J Med 2007 356: 911-920.
    • (2007) N Engl J Med , vol.356 , pp. 911-920
    • Tonetti, M.S.1    D'Aiuto, F.2    Nibali, L.3
  • 68
    • 65349091900 scopus 로고    scopus 로고
    • Treatment of periodontal disease results in improvements in endothelial dysfunction and reduction of the carotid intima-media thickness
    • Piconi S, Trabattoni D, Luraghi C, et al,. Treatment of periodontal disease results in improvements in endothelial dysfunction and reduction of the carotid intima-media thickness. FASEB J 2009 23: 1196-1204.
    • (2009) FASEB J , vol.23 , pp. 1196-1204
    • Piconi, S.1    Trabattoni, D.2    Luraghi, C.3
  • 69
    • 84893206328 scopus 로고    scopus 로고
    • Epidemiology of association between maternal periodontal disease and adverse pregnancy outcomes - Systematic review
    • Ide M, Papapanou PN,. Epidemiology of association between maternal periodontal disease and adverse pregnancy outcomes-systematic review. J Clin Periodontol 2013 40 (Suppl 14): S181-S194.
    • (2013) J Clin Periodontol , vol.40 , pp. S181-S194
    • Ide, M.1    Papapanou, P.N.2
  • 70
    • 42149188274 scopus 로고    scopus 로고
    • Periodontal disease definition may determine the association between periodontitis and pregnancy outcomes
    • Manau C, Echeverria A, Agueda A, et al,. Periodontal disease definition may determine the association between periodontitis and pregnancy outcomes. J Clin Periodontol 2008 35: 385-397.
    • (2008) J Clin Periodontol , vol.35 , pp. 385-397
    • Manau, C.1    Echeverria, A.2    Agueda, A.3
  • 71
    • 0036668592 scopus 로고    scopus 로고
    • Periodontal therapy may reduce the risk of preterm low birth weight in women with periodontal disease: A randomized controlled trial
    • Lopez NJ, Smith PC, Gutierrez J,. Periodontal therapy may reduce the risk of preterm low birth weight in women with periodontal disease: a randomized controlled trial. J Periodontol 2002 73: 911-924.
    • (2002) J Periodontol , vol.73 , pp. 911-924
    • Lopez, N.J.1    Smith, P.C.2    Gutierrez, J.3
  • 72
    • 0141519424 scopus 로고    scopus 로고
    • Periodontal disease and preterm birth: Results of a pilot intervention study
    • Jeffcoat MK, Hauth JC, Geurs NC, et al,. Periodontal disease and preterm birth: results of a pilot intervention study. J Periodontol 2003 74: 1214-1218.
    • (2003) J Periodontol , vol.74 , pp. 1214-1218
    • Jeffcoat, M.K.1    Hauth, J.C.2    Geurs, N.C.3
  • 73
    • 28644451545 scopus 로고    scopus 로고
    • Periodontal therapy reduces the rate of preterm low birth weight in women with pregnancy-associated gingivitis
    • Lopez NJ, Da Silva I, Ipinza J, et al,. Periodontal therapy reduces the rate of preterm low birth weight in women with pregnancy-associated gingivitis. J Periodontol 2005 76 (11 Suppl): 2144-2153.
    • (2005) J Periodontol , vol.76 , Issue.11 , pp. 2144-2153
    • Lopez, N.J.1    Da Silva, I.2    Ipinza, J.3
  • 74
    • 33750528565 scopus 로고    scopus 로고
    • Treatment of periodontal disease and the risk of preterm birth
    • Michalowicz BS, Hodges JS, DiAngelis AJ, et al,. Treatment of periodontal disease and the risk of preterm birth. N Engl J Med 2006 355: 1885-1894.
    • (2006) N Engl J Med , vol.355 , pp. 1885-1894
    • Michalowicz, B.S.1    Hodges, J.S.2    DiAngelis, A.J.3
  • 75
    • 73349122645 scopus 로고    scopus 로고
    • Treatment of periodontal disease during pregnancy: A randomized controlled trial
    • Newnham JP, Newnham IA, Ball CM, et al,. Treatment of periodontal disease during pregnancy: a randomized controlled trial. Obstet Gynecol 2009 114: 1239-1248.
    • (2009) Obstet Gynecol , vol.114 , pp. 1239-1248
    • Newnham, J.P.1    Newnham, I.A.2    Ball, C.M.3
  • 76
    • 69549133588 scopus 로고    scopus 로고
    • Effects of periodontal therapy on rate of preterm delivery: A randomized controlled trial
    • Offenbacher S, Beck JD, Jared HL, et al,. Effects of periodontal therapy on rate of preterm delivery: a randomized controlled trial. Obstet Gynecol 2009 114: 551-559.
    • (2009) Obstet Gynecol , vol.114 , pp. 551-559
    • Offenbacher, S.1    Beck, J.D.2    Jared, H.L.3
  • 77
    • 74749102935 scopus 로고    scopus 로고
    • Treatment of localized periodontal disease in pregnancy does not reduce the occurrence of preterm birth: Results from the Periodontal Infections and Prematurity Study (PIPS)
    • e1-e8
    • Macones GA, Parry S, Nelson DB, et al,. Treatment of localized periodontal disease in pregnancy does not reduce the occurrence of preterm birth: results from the Periodontal Infections and Prematurity Study (PIPS). Am J Obstet Gynecol 2010 202: 147.e1-e8.
    • (2010) Am J Obstet Gynecol , vol.202 , pp. 147
    • Macones, G.A.1    Parry, S.2    Nelson, D.B.3
  • 78
    • 84871931266 scopus 로고    scopus 로고
    • Effect of nonsurgical periodontal therapy and strict plaque control on preterm/low birth weight: A randomized controlled clinical trial
    • Weidlich P, Moreira CH, Fiorini T, et al,. Effect of nonsurgical periodontal therapy and strict plaque control on preterm/low birth weight: a randomized controlled clinical trial. Clin Oral Invest 2013 17: 37-44.
    • (2013) Clin Oral Invest , vol.17 , pp. 37-44
    • Weidlich, P.1    Moreira, C.H.2    Fiorini, T.3
  • 79
    • 78651390433 scopus 로고    scopus 로고
    • Obstetric outcomes after treatment of periodontal disease during pregnancy: Systematic review and meta-analysis
    • Polyzos NP, Polyzos IP, Zavos A, et al,. Obstetric outcomes after treatment of periodontal disease during pregnancy: systematic review and meta-analysis. BMJ 2010 341: c7017.
    • (2010) BMJ , vol.341 , pp. c7017
    • Polyzos, N.P.1    Polyzos, I.P.2    Zavos, A.3
  • 80
    • 84880330850 scopus 로고    scopus 로고
    • Treatment of periodontal disease and prevention of preterm birth: Systematic review and meta-analysis
    • Boutin A, Demers S, Roberge S, et al,. Treatment of periodontal disease and prevention of preterm birth: systematic review and meta-analysis. Am J Perinatol 2013 30: 537-544.
    • (2013) Am J Perinatol , vol.30 , pp. 537-544
    • Boutin, A.1    Demers, S.2    Roberge, S.3
  • 81
  • 82
    • 84865451307 scopus 로고    scopus 로고
    • Periodontitis and atherosclerotic vascular disease: What we know and why it is important
    • Papapanou PN, Trevisan M,. Periodontitis and atherosclerotic vascular disease: what we know and why it is important. J Am Dent Assoc 2012 143: 826-828.
    • (2012) J Am Dent Assoc , vol.143 , pp. 826-828
    • Papapanou, P.N.1    Trevisan, M.2
  • 83
    • 84890341830 scopus 로고    scopus 로고
    • The effect of nonsurgical periodontal therapy on hemoglobin A1c levels in persons with type 2 diabetes and chronic periodontitis: A randomized clinical trial
    • Engebretson SP, Hyman LG, Michalowicz BS, et al,. The effect of nonsurgical periodontal therapy on hemoglobin A1c levels in persons with type 2 diabetes and chronic periodontitis: a randomized clinical trial. JAMA 2013 310: 2523-2532.
    • (2013) JAMA , vol.310 , pp. 2523-2532
    • Engebretson, S.P.1    Hyman, L.G.2    Michalowicz, B.S.3


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