Periodontitis and atherosclerotic vascular disease: What we know and why it is important

Journal of the American Dental Association

Volumn 143, Issue 8, 2012, Pages 826-828

  Papapanou, Panos N ^a,b,c  

^a Division of Periodontics   (United States)

^b New York Presbyterian Hospital   (United States)

^c CITY UNIVERSITY OF NEW YORK MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84865451307     PISSN: 00028177     EISSN: None     Source Type: Journal    
DOI: 10.14219/jada.archive.2012.0275     Document Type: Editorial

References (8)

1. Lockhart PB, Bolger AF, Papapanou PN, et al; on behalf of the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, Council on Epidemiology and Prevention, Council on Peripheral Vascular Disease, and Council on Clinical Cardiology. Periodontal disease and atherosclerotic vascular disease: does the evidence support an independent association? A scientific statement from the American Heart Association (published online ahead of print April 18, 2012). Circulation 2012;125(20):2520-2544. doi:10.1161/ CIR.0b013e31825719f3.
2. Kebschull M, Demmer RT, Papapanou PN. "Gum bug, leave my heart alone!": epidemiologic and mechanistic evidence linking periodontal infections and atherosclerosis (published online ahead of print July 16, 2010). J Dent Res 2010;89(9):879-902. doi:10.1177/0022034510375281.
3. Paraskevas S, Huizinga JD, Loos BG. A systematic review and meta-analyses on C-reactive protein in relation to periodontitis (published online ahead of print Feb. 20, 2008). J Clin Periodontal 2008;35(4):277-290. doi:10.1111/j.l600-051X.2007.01173.x.
4. Ridker PM. Clinical application of C-reactive protein for cardiovascular disease detection and prevention. Circulation 2003;107(3):363-369.
5. Chen ZY, Chiang CH, Huang CC, et al. The association of tooth scaling and decreased cardiovascular disease: a nationwide population-based study (published online ahead of print April 4, 2012). Am J Med 2012;125(6):568-575. doi:10.1016/j. amjmed.2011.10.034.
6. Tonetti MS, D'Aiuto F, Nibali L, et al. Treatment of periodontitis and endothelial function. N Engl J Med 2007;356(9):911-920.
7. Piconi S, Trabattoni D, Luraghi C, et al. Treatment of periodontal disease results in improvements in endothelial dysfunction and reduction of the carotid intima-media thickness (published online ahead of print Dec. 12, 2008). FASEB J 2009;23(4):1196-1204. doi:10.10961fj.08.119578.
8. Offenbacher S, Beck JD, Moss K, et al. Results from the Periodontitis and Vascular Events (PAVE) Study: a pilot multicentered, randomized, controlled trial to study effects of periodontal therapy in a secondary prevention model of cardiovascular disease. J Periodontal 2009;80(2): 190-201.