-
1
-
-
33751096434
-
Natural combinatorial peptide libraries in cyanobacterial symbionts of marine ascidians
-
Donia MS, et al. (2006) Natural combinatorial peptide libraries in cyanobacterial symbionts of marine ascidians. Nat Chem Biol 2(12): 729-735.
-
(2006)
Nat Chem Biol
, vol.2
, Issue.12
, pp. 729-735
-
-
Donia, M.S.1
-
2
-
-
77953742146
-
Catalytic promiscuity in the biosynthesis of cyclic peptide secondary metabolites in planktonic marine cyanobacteria
-
Li B, et al. (2010) Catalytic promiscuity in the biosynthesis of cyclic peptide secondary metabolites in planktonic marine cyanobacteria. Proc Natl Acad Sci USA 107(23): 10430-10435.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.23
, pp. 10430-10435
-
-
Li, B.1
-
3
-
-
0024947834
-
Why are secondary metabolites (natural products) biosynthesized?
-
Williams DH, Stone MJ, Hauck PR, Rahman SK (1989) Why are secondary metabolites (natural products) biosynthesized? J Nat Prod 52(6): 1189-1208.
-
(1989)
J Nat Prod
, vol.52
, Issue.6
, pp. 1189-1208
-
-
Williams, D.H.1
Stone, M.J.2
Hauck, P.R.3
Rahman, S.K.4
-
4
-
-
0026380997
-
On the evolution of plant secondary chemical diversity
-
Jones CG, Firn RD (1991) On the evolution of plant secondary chemical diversity. Phil Trans 333(1267): 273-280.
-
(1991)
Phil Trans
, vol.333
, Issue.1267
, pp. 273-280
-
-
Jones, C.G.1
Firn, R.D.2
-
5
-
-
34250707968
-
One pathway, many products
-
Fischbach MA, Clardy J (2007) One pathway, many products. Nat Chem Biol 3(7): 353-355.
-
(2007)
Nat Chem Biol
, vol.3
, Issue.7
, pp. 353-355
-
-
Fischbach, M.A.1
Clardy, J.2
-
6
-
-
18844410256
-
Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella
-
Schmidt EW, et al. (2005) Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella. Proc Natl Acad Sci USA 102(20): 7315-7320.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.20
, pp. 7315-7320
-
-
Schmidt, E.W.1
-
7
-
-
43749113148
-
A global assembly line for cyanobactins
-
Donia MS, Ravel J, Schmidt EW (2008) A global assembly line for cyanobactins. Nat Chem Biol 4(6): 341-343.
-
(2008)
Nat Chem Biol
, vol.4
, Issue.6
, pp. 341-343
-
-
Donia, M.S.1
Ravel, J.2
Schmidt, E.W.3
-
8
-
-
84928138620
-
Assessing the combinatorial potential of the RiPP cyanobactin tru pathway
-
Ruffner DE, Schmidt EW, Heemstra JR (2015) Assessing the combinatorial potential of the RiPP cyanobactin tru pathway. ACS Synth Biol 4(4): 482-492.
-
(2015)
ACS Synth Biol
, vol.4
, Issue.4
, pp. 482-492
-
-
Ruffner, D.E.1
Schmidt, E.W.2
Heemstra, J.R.3
-
9
-
-
77950269149
-
Insights into heterocyclization from two highly similar enzymes
-
McIntosh JA, Donia MS, Schmidt EW (2010) Insights into heterocyclization from two highly similar enzymes. J Am Chem Soc 132(12): 4089-4091.
-
(2010)
J Am Chem Soc
, vol.132
, Issue.12
, pp. 4089-4091
-
-
McIntosh, J.A.1
Donia, M.S.2
Schmidt, E.W.3
-
10
-
-
67749142086
-
Using marine natural products to discover a protease that catalyzes peptide macrocyclization of diverse substrates
-
Lee J, McIntosh J, Hathaway BJ, Schmidt EW (2009) Using marine natural products to discover a protease that catalyzes peptide macrocyclization of diverse substrates. J Am Chem Soc 131(6): 2122-2124.
-
(2009)
J Am Chem Soc
, vol.131
, Issue.6
, pp. 2122-2124
-
-
Lee, J.1
McIntosh, J.2
Hathaway, B.J.3
Schmidt, E.W.4
-
11
-
-
84937735393
-
Modularity of RiPP enzymes enables designed synthesis of decorated peptides
-
Sardar D, Lin Z, Schmidt EW (2015) Modularity of RiPP enzymes enables designed synthesis of decorated peptides. Chem Biol 22(7): 907-916.
-
(2015)
Chem Biol
, vol.22
, Issue.7
, pp. 907-916
-
-
Sardar, D.1
Lin, Z.2
Schmidt, E.W.3
-
12
-
-
84855646831
-
Ribosomal route to small-molecule diversity
-
Tianero MD, Donia MS, Young TS, Schultz PG, Schmidt EW (2012) Ribosomal route to small-molecule diversity. J Am Chem Soc 134(1): 418-425.
-
(2012)
J Am Chem Soc
, vol.134
, Issue.1
, pp. 418-425
-
-
Tianero, M.D.1
Donia, M.S.2
Young, T.S.3
Schultz, P.G.4
Schmidt, E.W.5
-
13
-
-
84903151161
-
One-pot synthesis of azoline-containing peptides in a cell-free translation system integrated with a posttranslational cyclodehydratase
-
Goto Y, Ito Y, Kato Y, Tsunoda S, Suga H (2014) One-pot synthesis of azoline-containing peptides in a cell-free translation system integrated with a posttranslational cyclodehydratase. Chem Biol 21(6): 766-774.
-
(2014)
Chem Biol
, vol.21
, Issue.6
, pp. 766-774
-
-
Goto, Y.1
Ito, Y.2
Kato, Y.3
Tsunoda, S.4
Suga, H.5
-
14
-
-
84917710839
-
An efficient method for the in vitro production of azol(in)ebased cyclic peptides
-
Houssen WE, et al. (2014) An efficient method for the in vitro production of azol(in)ebased cyclic peptides. Angew Chem Int Ed Engl 53(51): 14171-14174.
-
(2014)
Angew Chem Int Ed Engl
, vol.53
, Issue.51
, pp. 14171-14174
-
-
Houssen, W.E.1
-
15
-
-
84924229934
-
Recognition sequences and substrate evolution in cyanobactin biosynthesis
-
Sardar D, Pierce E, McIntosh JA, Schmidt EW (2015) Recognition sequences and substrate evolution in cyanobactin biosynthesis. ACS Synth Biol 4(2): 167-176.
-
(2015)
ACS Synth Biol
, vol.4
, Issue.2
, pp. 167-176
-
-
Sardar, D.1
Pierce, E.2
McIntosh, J.A.3
Schmidt, E.W.4
-
16
-
-
79955979636
-
Accessing the hidden majority of marine natural products through metagenomics
-
Donia MS, Ruffner DE, Cao S, Schmidt EW (2011) Accessing the hidden majority of marine natural products through metagenomics. ChemBioChem 12(8): 1230-1236.
-
(2011)
ChemBioChem
, vol.12
, Issue.8
, pp. 1230-1236
-
-
Donia, M.S.1
Ruffner, D.E.2
Cao, S.3
Schmidt, E.W.4
-
17
-
-
0038391517
-
Engineering a mevalonate pathway in Escherichia coli for production of terpenoids
-
Martin VJ, Pitera DJ, Withers ST, Newman JD, Keasling JD (2003) Engineering a mevalonate pathway in Escherichia coli for production of terpenoids. Nat Biotechnol 21(7): 796-802.
-
(2003)
Nat Biotechnol
, vol.21
, Issue.7
, pp. 796-802
-
-
Martin, V.J.1
Pitera, D.J.2
Withers, S.T.3
Newman, J.D.4
Keasling, J.D.5
-
18
-
-
0000192163
-
Patellins 1-6 and trunkamide A: Novel cyclic hexa-, hepta- and octa-peptides from colonial ascidians, Lissoclinum sp
-
Carroll AR, et al. (1996) Patellins 1-6 and trunkamide A: Novel cyclic hexa-, hepta- and octa-peptides from colonial ascidians, Lissoclinum sp. Aust J Chem 49(6): 659-667.
-
(1996)
Aust J Chem
, vol.49
, Issue.6
, pp. 659-667
-
-
Carroll, A.R.1
-
19
-
-
84864501401
-
Characterization of two neuronal subclasses through constellation pharmacology
-
Teichert RW, et al. (2012) Characterization of two neuronal subclasses through constellation pharmacology. Proc Natl Acad Sci USA 109(31): 12758-12763.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.31
, pp. 12758-12763
-
-
Teichert, R.W.1
-
20
-
-
84893845581
-
Using constellation pharmacology to define comprehensively a somatosensory neuronal subclass
-
Teichert RW, Memon T, Aman JW, Olivera BM (2014) Using constellation pharmacology to define comprehensively a somatosensory neuronal subclass. Proc Natl Acad Sci USA 111(6): 2319-2324.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, Issue.6
, pp. 2319-2324
-
-
Teichert, R.W.1
Memon, T.2
Aman, J.W.3
Olivera, B.M.4
-
22
-
-
0021871249
-
Potentiation by sulfide of hydrogen peroxide-induced killing of Escherichia coli
-
Berglin EH, Carlsson J (1985) Potentiation by sulfide of hydrogen peroxide-induced killing of Escherichia coli. Infect Immun 49(3): 538-543.
-
(1985)
Infect Immun
, vol.49
, Issue.3
, pp. 538-543
-
-
Berglin, E.H.1
Carlsson, J.2
-
23
-
-
22144456756
-
Identification and functional analysis of Escherichia coli cysteine desulfhydrases
-
Awano N, Wada M, Mori H, Nakamori S, Takagi H (2005) Identification and functional analysis of Escherichia coli cysteine desulfhydrases. Appl EnvironMicrobiol 71(7): 4149-4152.
-
(2005)
Appl EnvironMicrobiol
, vol.71
, Issue.7
, pp. 4149-4152
-
-
Awano, N.1
Wada, M.2
Mori, H.3
Nakamori, S.4
Takagi, H.5
-
24
-
-
0000907566
-
Catalytic properties of tryptophanase, a multifunctional pyridoxal phosphate enzyme
-
Newton WA, Snell EE (1964) Catalytic properties of tryptophanase, a multifunctional pyridoxal phosphate enzyme. Proc Natl Acad Sci USA 51: 382-389.
-
(1964)
Proc Natl Acad Sci USA
, vol.51
, pp. 382-389
-
-
Newton, W.A.1
Snell, E.E.2
-
25
-
-
0029923954
-
From peptide precursors to oxazole and thiazole-containing peptide antibiotics: Microcin B17 synthase
-
Li YM, Milne JC, Madison LL, Kolter R, Walsh CT (1996) From peptide precursors to oxazole and thiazole-containing peptide antibiotics: Microcin B17 synthase. Science 274(5290): 1188-1193.
-
(1996)
Science
, vol.274
, Issue.5290
, pp. 1188-1193
-
-
Li, Y.M.1
Milne, J.C.2
Madison, L.L.3
Kolter, R.4
Walsh, C.T.5
-
26
-
-
84873430621
-
Antimicrobial drug resistance affects broad changes in metabolomic phenotype in addition to secondary metabolism
-
Derewacz DK, Goodwin CR, McNees CR, McLean JA, Bachmann BO (2013) Antimicrobial drug resistance affects broad changes in metabolomic phenotype in addition to secondary metabolism. Proc Natl Acad Sci USA 110(6): 2336-2341.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.6
, pp. 2336-2341
-
-
Derewacz, D.K.1
Goodwin, C.R.2
McNees, C.R.3
McLean, J.A.4
Bachmann, B.O.5
-
27
-
-
84903714301
-
Phenotypic mapping of metabolic profiles using selforganizing maps of high-dimensional mass spectrometry data
-
Goodwin CR, et al. (2014) Phenotypic mapping of metabolic profiles using selforganizing maps of high-dimensional mass spectrometry data. Anal Chem 86(13): 6563-6571.
-
(2014)
Anal Chem
, vol.86
, Issue.13
, pp. 6563-6571
-
-
Goodwin, C.R.1
-
28
-
-
77952905782
-
The L-cysteine/L-cystine shuttle system provides reducing equivalents to the periplasm in Escherichia coli
-
Ohtsu I, et al. (2010) The L-cysteine/L-cystine shuttle system provides reducing equivalents to the periplasm in Escherichia coli. J Biol Chem 285(23): 17479-17487.
-
(2010)
J Biol Chem
, vol.285
, Issue.23
, pp. 17479-17487
-
-
Ohtsu, I.1
-
29
-
-
74949103637
-
H2S signals through protein S-sulfhydration
-
Mustafa AK, et al. (2009) H2S signals through protein S-sulfhydration. Sci Signal 2(96): Ra72.
-
(2009)
Sci Signal
, vol.2
, Issue.96
, pp. ra72
-
-
Mustafa, A.K.1
-
31
-
-
84924918487
-
Proteome-wide light/dark modulation of thiol oxidation in cyanobacteria revealed by quantitative site-specific redox proteomics
-
Guo J, et al. (2014) Proteome-wide light/dark modulation of thiol oxidation in cyanobacteria revealed by quantitative site-specific redox proteomics. Mol Cell Proteomics 13(12): 3270-3285.
-
(2014)
Mol Cell Proteomics
, vol.13
, Issue.12
, pp. 3270-3285
-
-
Guo, J.1
-
32
-
-
84928139480
-
The circadian oscillator in Synechococcus elongatus controls metabolite partitioning during diurnal growth
-
Diamond S, Jun D, Rubin BE, Golden SS (2015) The circadian oscillator in Synechococcus elongatus controls metabolite partitioning during diurnal growth. Proc Natl Acad Sci USA 112(15): E1916-E1925.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, Issue.15
, pp. e1916-e1925
-
-
Diamond, S.1
Jun, D.2
Rubin, B.E.3
Golden, S.S.4
-
33
-
-
78149276862
-
Circular logic: Nonribosomal peptide-like macrocyclization with a ribosomal peptide catalyst
-
McIntosh JA, et al. (2010) Circular logic: Nonribosomal peptide-like macrocyclization with a ribosomal peptide catalyst. J Am Chem Soc 132(44): 15499-15501.
-
(2010)
J Am Chem Soc
, vol.132
, Issue.44
, pp. 15499-15501
-
-
McIntosh, J.A.1
-
34
-
-
80052087588
-
Enzymatic basis of ribosomal peptide prenylation in cyanobacteria
-
McIntosh JA, Donia MS, Nair SK, Schmidt EW (2011) Enzymatic basis of ribosomal peptide prenylation in cyanobacteria. J Am Chem Soc 133(34): 13698-13705.
-
(2011)
J Am Chem Soc
, vol.133
, Issue.34
, pp. 13698-13705
-
-
McIntosh, J.A.1
Donia, M.S.2
Nair, S.K.3
Schmidt, E.W.4
-
35
-
-
84919344174
-
A price to pay for relaxed substrate specificity: A comparative kinetic analysis of the class II lanthipeptide synthetases ProcM and HalM2
-
Thibodeaux CJ, Ha T, van der Donk WA (2014) A price to pay for relaxed substrate specificity: A comparative kinetic analysis of the class II lanthipeptide synthetases ProcM and HalM2. J Am Chem Soc 136(50): 17513-17529.
-
(2014)
J Am Chem Soc
, vol.136
, Issue.50
, pp. 17513-17529
-
-
Thibodeaux, C.J.1
Ha, T.2
Van Der Donk, W.A.3
-
36
-
-
84928479646
-
Product formation by the promiscuous lanthipeptide synthetase ProcM is under kinetic control
-
Yu Y, Mukherjee S, van der Donk WA (2015) Product formation by the promiscuous lanthipeptide synthetase ProcM is under kinetic control. J AmChemSoc 137(15): 5140-5148.
-
(2015)
J AmChemSoc
, vol.137
, Issue.15
, pp. 5140-5148
-
-
Yu, Y.1
Mukherjee, S.2
Van Der Donk, W.A.3
-
37
-
-
0025147732
-
Studies on the solutionand solid-state structure of patellin 2
-
Zabriskie TM, Foster MP, Stout TJ, Clardy J, Ireland CM (1990) Studies on the solutionand solid-state structure of patellin 2. J Am Chem Soc 112(22): 8080-8084.
-
(1990)
J Am Chem Soc
, vol.112
, Issue.22
, pp. 8080-8084
-
-
Zabriskie, T.M.1
Foster, M.P.2
Stout, T.J.3
Clardy, J.4
Ireland, C.M.5
-
38
-
-
62349139062
-
A Darwinian view of metabolism: Molecular properties determine fitness
-
Firn RD, Jones CG (2009) A Darwinian view of metabolism: Molecular properties determine fitness. J Exp Bot 60(3): 719-726.
-
(2009)
J Exp Bot
, vol.60
, Issue.3
, pp. 719-726
-
-
Firn, R.D.1
Jones, C.G.2
-
39
-
-
84881488183
-
The remarkable pliability and promiscuity of specialized metabolism
-
Weng JK, Noel JP (2012) The remarkable pliability and promiscuity of specialized metabolism. Cold Spring Harb Symp Quant Biol 77: 309-320.
-
(2012)
Cold Spring Harb Symp Quant Biol
, vol.77
, pp. 309-320
-
-
Weng, J.K.1
Noel, J.P.2
-
40
-
-
33845992556
-
Conus peptides: Biodiversity-based discovery and exogenomics
-
Olivera BM (2006) Conus peptides: Biodiversity-based discovery and exogenomics. J Biol Chem 281(42): 31173-31177.
-
(2006)
J Biol Chem
, vol.281
, Issue.42
, pp. 31173-31177
-
-
Olivera, B.M.1
|