Genetic editing of HLA expression in hematopoietic stem cells to broaden their human application

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Torikai, Hiroki ^a   Mi, Tiejuan ^a   Gragert, Loren ^b   Maiers, Martin ^b   Najjar, Amer ^a   Ang, Sonny ^a   Maiti, Sourindra ^a   Dai, Jianliang ^a   Switzer, Kirsten C ^a   Huls, Helen ^a   Dulay, Gladys P ^c   Reik, Andreas ^c   Rebar, Edward J ^c   Holmes, Michael C ^c   Gregory, Philip D ^c   Champlin, Richard E ^a   Shpall, Elizabeth J ^a   Cooper, Laurence J N ^a,d  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b NATIONAL MARROW DONOR PROGRAM   (United States)

^c SANGAMO BIOSCIENCES INC   (United States)

^d Ziopharm Oncology Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEASE; HLA A ANTIGEN; HLA B ANTIGEN; HLA C ANTIGEN; HLA DRB1 ANTIGEN; ZINC FINGER PROTEIN;

ALLELE; ALLOTRANSPLANTATION; ANCESTRY GROUP; ANIMAL; CYTOLOGY; DONOR SELECTION; ETHICS; ETHNOLOGY; GENE DELETION; GENE EXPRESSION; GENETIC ENGINEERING; GENETICS; HEALTH CARE DELIVERY; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOCOMPATIBILITY TEST; HUMAN; IMMUNOLOGY; METABOLISM; MOUSE; PROCEDURES; UNRELATED DONORS; XENOGRAFT;

ALLELES; ANIMALS; CONTINENTAL POPULATION GROUPS; DEOXYRIBONUCLEASES; DONOR SELECTION; GENE DELETION; GENE EXPRESSION; GENETIC ENGINEERING; HEALTH SERVICES ACCESSIBILITY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HISTOCOMPATIBILITY TESTING; HLA-A ANTIGENS; HLA-B ANTIGENS; HLA-C ANTIGENS; HLA-DRB1 CHAINS; HUMANS; MICE; TRANSPLANTATION, HETEROLOGOUS; TRANSPLANTATION, HOMOLOGOUS; UNRELATED DONORS; ZINC FINGERS;

EID: 84959010559     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep21757     Document Type: Article

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