Impact of donor-specific anti-HLA antibodies on graft failure and survival after reduced intensity conditioning-unrelated cord blood transplantation: A Eurocord, société Francophone d'Histocompatibilité et d'immunogénétique (SFHI) and Société Française de Greffe de Moelle et de Thérapie cellulaire (SFGM-TC) analysis

Haematologica

Volumn 98, Issue 7, 2013, Pages 1154-1160

  Ruggeri, Annalisa ^a,b   Rocha, Vanderson ^a   Masson, Emeline ^a   Labopin, Myriam ^c   Cunha, Renato ^a   Absi, Lena ^d   Boudifa, Ali ^e   Coeffic, Brigitte ^f   Devys, Anne ^d   De Matteis, Muriel ^g   Dubois, Valérie ^d   Hanau, Daniel ^d   Hau, Françoise ^h   Jollet, Isabelle ⁱ   Masson, Dominique ^d   Pedron, Beatrice ^j   Perrier, Pascale ^k   Picard, Christophe ^d   Ramouneau Pigot, Annie ^l   Volt, Fernanda ^a   Charron, Dominique ^a   Gluckman, Eliane ^a   Loiseau, Pascale ^a   more..

^a SAINT LOUIS HOSPITAL   (France)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c HÔPITAL SAINT ANTOINE   (France)

^d ETABLISSEMENT FRANÇAIS DU SANG   (France)

^e PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^f EFS Pays de la Loire   (France)

^g UNIVERSITY HOSPITAL OF NICE   (France)

^h Laboratory of Histocompatibility   (France)

ⁱ EFS CA   (France)

^j HÔPITAL ROBERT DEBRÉ   (France)

^k CHU NANCY BRABOIS   (France)

^l HÔPITAL SAINT ELOI   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BUSULFAN; HLA ANTIBODY; THYMOCYTE ANTIBODY;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CHIMERA; CORD BLOOD STEM CELL TRANSPLANTATION; ENGRAFTMENT; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENCE; GRAFT FAILURE; GRAFT INFECTION; GRAFT SURVIVAL; GRAFT VERSUS HOST REACTION; HLA MATCHING; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIPLE ORGAN FAILURE; OUTCOME ASSESSMENT; REDUCED INTENSITY CONDITIONING; RELAPSE; THROMBOCYTE TRANSFUSION; WHOLE BODY RADIATION;

ADOLESCENT; ADULT; AGED; AUTOANTIBODIES; CHILD; CHILD, PRESCHOOL; FEMALE; FETAL BLOOD; FOLLOW-UP STUDIES; FRANCE; GRAFT SURVIVAL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOCOMPATIBILITY; HLA ANTIGENS; HUMANS; INFANT; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SOCIETIES, MEDICAL; SURVIVAL RATE; TISSUE DONORS; TRANSPLANTATION CONDITIONING; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84879582606     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2012.077685     Document Type: Article

References (28)

1. Gluckman E, Rocha V, Arcese W, Michel G, Sanz G, Chan KW, et al. Factors associated with outcomes of unrelated cord blood transplant: guidelines for donor choice. Exp Hematol. 2004;32(4):397-407.
2. Eapen M, Rubinstein P, Zhang MJ, Stevens C, Kurtzberg J, Scaradavou A, et al. Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukaemia: a comparison study. Lancet. 2007;369(9577): 1947-1954.
3. Eapen M, Rocha V, Sanz G, Scaradavou A, Zhang MJ, Arcese W, et al. Effect of graft source on unrelated donor haemopoietic stem-cell transplantation in adults with acute leukaemia: a retrospective analysis. Lancet Oncol. 2010;11(7):653-660.
4. Rocha V, Labopin M, Sanz G, Arcese W, Schwerdtfeger R, Bosi A, et al. Transplants of umbilical-cord blood or bone marrow from unrelated donors in adults with acute leukemia. N Engl J Med. 2004;351(22): 2276-2285.
5. Brunstein CG, Fuchs EJ, Carter SL, Karanes C, Costa LJ, Wu J, et al. Alternative donor transplantation after reduced intensity conditioning: results of parallel phase 2 trials using partially HLA-mismatched related bone marrow or unrelated double umbilical cord blood grafts. Blood. 2011;118(2):282-288.
6. Brunstein CG, Gutman JA, Weisdorf DJ, Woolfrey AE, Defor TE, Gooley TA, et al. Allogeneic hematopoietic cell transplantation for hematologic malignancy: relative risks and benefits of double umbilical cord blood. Blood. 2010;116(22):4693-4699.
7. Delaney C, Ratajczak MZ, Laughlin MJ. Strategies to enhance umbilical cord blood stem cell engraftment in adult patients. Expert Rev Hematol. 2010;3(3):273-83.
8. Rocha V, Broxmeyer HE. New approaches for improving engraftment after cord blood transplantation. Biol Blood Marrow Transplant. 2010;16(1 Suppl):S126-S132.
9. Delaney C, Heimfeld S, Brashem-Stein C, Voorhies H, Manger RL, Bernstein ID. Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution. Nat Med. 2010;16 (2):232-236.
10. Eapen M, Klein JP, Sanz GF, Spellman S, Ruggeri A, Anasetti C, et al. Effect of donorrecipient HLA matching at HLA A, B, C, and DRB1 on outcomes after umbilicalcord blood transplantation for leukaemia and myelodysplastic syndrome: a retrospective analysis. Lancet Oncol. 2011;12(13):1214-1251.
11. Schonewille H, Haak HL, van Zijl AM. Alloimmunization after blood transfusion in patients with hematologic and oncologic diseases. Transfusion. 1999;39(7):763-771.
12. Idica A, Sasaki N, Hardy S, Terasaki P. Unexpected frequencies of HLA antibody specificities present in sera of multitransfused patients. Clin Transpl. 2006;139-159.
13. Spellman S, Bray R, Rosen-Bronson S, Haagenson M, Klein J, Flesch S, et al. The detection of donor-directed, HLA-specific alloantibodies in recipients of unrelated hematopoietic cell transplantation is predictive of graft failure. Blood. 2010;115 (13):2704-2708.
14. Morales-Buenrostro LE, Terasaki PI, Marino-Vazquez LA, Lee JH, El-Awar N, Alberu J. Natural human leukocyte antigen antibodies found in nonalloimmunized healthy males. Transplantation. 2008;86(8): 1111-1115.
15. Cutler C, Kim HT, Sun L, Sese D, Glotzbecker B, Armand P, et al. Donor-specific anti-HLA antibodies predict outcome in double umbilical cord blood transplantation. Blood. 2011;118(25):6691-6697.
16. Brunstein CG, Noreen H, DeFor TE, Maurer D, Miller JS, Wagner JE. Anti-HLA antibodies in double umbilical cord blood transplantation. Biol Blood Marrow Transplant. 2011;17(11):1704-1708.
17. Glucksberg H, Storb R, Fefer A, Buckner CD, Neiman PE, Clift RA, et al. Clinical manifestations of graft-versus-host disease in human recipients of marrow from HL-Amatched sibling donors. Transplantation. 1974;18(4):295-304.
18. Cox DR. Regression model and life tables. J R Stat Soc B. 1972;34:187-200.
19. Fine JP, Gray RJ. A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc. 1999;94(446): 496-499.
20. Patel AM, Pancoska C, Mulgaonkar S, Weng FL. Renal transplantation in patients with pre-transplant donor-specific antibodies and negative flow cytometry crossmatches. Am J Transplant. 2007;7(10):2371-2377.
21. Yoshihara S, Maruya E, Taniguchi K, Kaida K, Kato R, Inoue T, et al. Risk and prevention of graft failure in patients with preexisting donor-specific HLA antibodies undergoing unmanipulated haploidentical SCT. Bone Marrow Transplant. 2012;47(4):508-515.
22. Takanashi M, Atsuta Y, Fujiwara K, Kodo H, Kai S, Sato H, et al. The impact of anti-HLA antibodies on unrelated cord blood transplantations. Blood. 2010;116(15):2839-2846.
23. Gutman JA, McKinney SK, Pereira S, Warnock SL, Smith AG, Woolfrey AE, et al. Prospective monitoring for alloimmunization in cord blood transplantation: virtual crossmatch can be used to demonstrate donor-directed antibodies. Transplantation. 2009;87(3):415-418.
24. Stevens CE, Carrier C, Carpenter C, Sung D, Scaradavou A. HLA mismatch direction in cord blood transplantation: impact on outcome and implications for cord blood unit selection. Blood. 2011;118(14):3969-3978.
25. van Rood JJ, Stevens CE, Smits J, Carrier C, Carpenter C, Scaradavou A. Reexposure of cord blood to noninherited maternal HLA antigens improves transplant outcome in hematological malignancies. Proc Natl Acad Sci USA. 2009;106(47):19952-19957.
26. Rocha V, Spellman S, Zhang MJ, Ruggeri A, Purtill D, Brady C, et al. Effect of HLAmatching recipients to donor noninherited maternal antigens on outcomes after mismatched umbilical cord blood transplantation for hematologic malignancy. Biol Biol Blood Marrow Transplant. 2012;18(12): 1890-1896.
27. Peffault de Latour R, Purtill D, Ruggeri A, Sanz G, Michel G, Gandemer V, et al. Influence of nucleated cell dose on overall survival of unrelated cord blood transplantation for patients with severe acquired aplastic anemia: a study by eurocord and the aplastic anemia working party of the European group for blood and marrow transplantation. Biol Blood Marrow Transplant. 2011;17(1):78-85.
28. [No authors listed]. Leukocyte reduction and ultraviolet B irradiation of platelets to prevent alloimmunization and refractoriness to platelet transfusions. The Trial to Reduce Alloimmunization to Platelets Study Group. N Engl J Med. 1997; 337(26):1861-1869.