-
1
-
-
77956416339
-
Autophagy in mammalian development and differentiation
-
Mizushima, N., and Levine, B. (2010) Autophagy in mammalian development and differentiation. Nat. Cell Biol. 12, 823-830
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 823-830
-
-
Mizushima, N.1
Levine, B.2
-
2
-
-
50249103834
-
The cell biology of autophagy in metazoans: A developing story
-
Meléndez, A., and Neufeld, T. P. (2008) The cell biology of autophagy in metazoans: a developing story. Development 135, 2347-2360
-
(2008)
Development
, vol.135
, pp. 2347-2360
-
-
Meléndez, A.1
Neufeld, T.P.2
-
3
-
-
36249025723
-
Autophagy: Process and function
-
Mizushima, N. (2007) Autophagy: process and function. Genes Dev. 21, 2861-2873
-
(2007)
Genes Dev.
, vol.21
, pp. 2861-2873
-
-
Mizushima, N.1
-
4
-
-
0026668042
-
Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction
-
Takeshige, K., Baba, M., Tsuboi, S., Noda, T., and Ohsumi, Y. (1992) Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction. J. Cell Biol. 119, 301-311
-
(1992)
J. Cell Biol.
, vol.119
, pp. 301-311
-
-
Takeshige, K.1
Baba, M.2
Tsuboi, S.3
Noda, T.4
Ohsumi, Y.5
-
5
-
-
0027424777
-
Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
-
Tsukada, M., and Ohsumi, Y. (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett. 333, 169-174
-
(1993)
FEBS Lett.
, vol.333
, pp. 169-174
-
-
Tsukada, M.1
Ohsumi, Y.2
-
6
-
-
0027936092
-
Isolation of autophagocytosis mutants of Saccharomyces cerevisiae
-
Thumm, M., Egner, R., Koch, B., Schlumpberger, M., Straub, M., Veenhuis, M., and Wolf, D. H. (1994) Isolation of autophagocytosis mutants of Saccharomyces cerevisiae. FEBS Lett. 349, 275-280
-
(1994)
FEBS Lett.
, vol.349
, pp. 275-280
-
-
Thumm, M.1
Egner, R.2
Koch, B.3
Schlumpberger, M.4
Straub, M.5
Veenhuis, M.6
Wolf, D.H.7
-
7
-
-
84891745088
-
Historical landmarks of autophagy research
-
Ohsumi, Y. (2014) Historical landmarks of autophagy research. Cell Res. 24, 9-23
-
(2014)
Cell Res.
, vol.24
, pp. 9-23
-
-
Ohsumi, Y.1
-
8
-
-
80054025654
-
The role of Atg proteins in autophagosome formation
-
Mizushima, N., Yoshimori, T., and Ohsumi, Y. (2011) The role of Atg proteins in autophagosome formation. Annu. Rev. Cell Dev. Biol. 27, 107-132
-
(2011)
Annu. Rev. Cell Dev. Biol.
, vol.27
, pp. 107-132
-
-
Mizushima, N.1
Yoshimori, T.2
Ohsumi, Y.3
-
9
-
-
84891747382
-
The machinery of macroautophagy
-
Feng, Y., He, D., Yao, Z., and Klionsky, D. J. (2014) The machinery of macroautophagy. Cell Res. 24, 24-41
-
(2014)
Cell Res.
, vol.24
, pp. 24-41
-
-
Feng, Y.1
He, D.2
Yao, Z.3
Klionsky, D.J.4
-
10
-
-
0034683568
-
Tor-mediated induction of autophagy via an Apg1 protein kinase complex
-
Kamada, Y., Funakoshi, T., Shintani, T., Nagano, K., Ohsumi, M., and Ohsumi, Y. (2000) Tor-mediated induction of autophagy via an Apg1 protein kinase complex. J. Cell Biol. 150, 1507-1513
-
(2000)
J. Cell Biol.
, vol.150
, pp. 1507-1513
-
-
Kamada, Y.1
Funakoshi, T.2
Shintani, T.3
Nagano, K.4
Ohsumi, M.5
Ohsumi, Y.6
-
11
-
-
18244394277
-
Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy
-
Kabeya, Y., Kamada, Y., Baba, M., Takikawa, H., Sasaki, M., and Ohsumi, Y. (2005) Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy. Mol. Biol. Cell 16, 2544-2553
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 2544-2553
-
-
Kabeya, Y.1
Kamada, Y.2
Baba, M.3
Takikawa, H.4
Sasaki, M.5
Ohsumi, Y.6
-
12
-
-
33846514235
-
Hierarchy of Atg proteins in pre-autophagosomal structure organization
-
Suzuki, K., Kubota, Y., Sekito, T., and Ohsumi, Y. (2007) Hierarchy of Atg proteins in pre-autophagosomal structure organization. Genes Cells 12, 209-218
-
(2007)
Genes Cells
, vol.12
, pp. 209-218
-
-
Suzuki, K.1
Kubota, Y.2
Sekito, T.3
Ohsumi, Y.4
-
13
-
-
43149125546
-
Organization of the pre-autophagosomal structure responsible for autophagosome formation
-
Kawamata, T., Kamada, Y., Kabeya, Y., Sekito, T., and Ohsumi, Y. (2008) Organization of the pre-autophagosomal structure responsible for autophagosome formation. Mol. Biol. Cell 19, 2039-2050
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 2039-2050
-
-
Kawamata, T.1
Kamada, Y.2
Kabeya, Y.3
Sekito, T.4
Ohsumi, Y.5
-
14
-
-
39449108917
-
The Atg1 kinase complex is involved in the regulation of protein recruitment to initiate sequestering vesicle formation for nonspecific autophagy in Saccharomyces cerevisiae
-
Cheong, H., Nair, U., Geng, J., and Klionsky, D. J. (2008) The Atg1 kinase complex is involved in the regulation of protein recruitment to initiate sequestering vesicle formation for nonspecific autophagy in Saccharomyces cerevisiae. Mol. Biol. Cell 19, 668-681
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 668-681
-
-
Cheong, H.1
Nair, U.2
Geng, J.3
Klionsky, D.J.4
-
15
-
-
21844470747
-
Atg17 regulates the magnitude of the autophagic response
-
Cheong, H., Yorimitsu, T., Reggiori, F., Legakis, J. E., Wang, C. W., and Klionsky, D. J. (2005) Atg17 regulates the magnitude of the autophagic response. Mol. Biol. Cell 16, 3438-3453
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 3438-3453
-
-
Cheong, H.1
Yorimitsu, T.2
Reggiori, F.3
Legakis, J.E.4
Wang, C.W.5
Klionsky, D.J.6
-
16
-
-
75749090429
-
Tor directly controls the Atg1 kinase complex to regulate autophagy
-
Kamada, Y., Yoshino, K., Kondo, C., Kawamata, T., Oshiro, N., Yonezawa, K., and Ohsumi, Y. (2010) Tor directly controls the Atg1 kinase complex to regulate autophagy. Mol. Cell. Biol. 30, 1049-1058
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 1049-1058
-
-
Kamada, Y.1
Yoshino, K.2
Kondo, C.3
Kawamata, T.4
Oshiro, N.5
Yonezawa, K.6
Ohsumi, Y.7
-
17
-
-
84901986623
-
Structural basis of starvation-induced assembly of the autophagy initiation complex
-
Fujioka, Y., Suzuki, S. W., Yamamoto, H., Kondo-Kakuta, C., Kimura, Y., Hirano, H., Akada, R., Inagaki, F., Ohsumi, Y., and Noda, N. N. (2014) Structural basis of starvation-induced assembly of the autophagy initiation complex. Nat. Struct. Mol. Biol. 21, 513-521
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 513-521
-
-
Fujioka, Y.1
Suzuki, S.W.2
Yamamoto, H.3
Kondo-Kakuta, C.4
Kimura, Y.5
Hirano, H.6
Akada, R.7
Inagaki, F.8
Ohsumi, Y.9
Noda, N.N.10
-
18
-
-
66449083078
-
ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy
-
Ganley, I. G., Lam du, H., Wang, J., Ding, X., Chen, S., and Jiang, X. (2009) ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy. J. Biol. Chem. 284, 12297-12305
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 12297-12305
-
-
Ganley, I.G.1
Lam Du, H.2
Wang, J.3
Ding, X.4
Chen, S.5
Jiang, X.6
-
19
-
-
43149090064
-
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
-
Hara, T., Takamura, A., Kishi, C., Iemura, S., Natsume, T., Guan, J. L., and Mizushima, N. (2008) FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells. J. Cell Biol. 181, 497-510
-
(2008)
J. Cell Biol.
, vol.181
, pp. 497-510
-
-
Hara, T.1
Takamura, A.2
Kishi, C.3
Iemura, S.4
Natsume, T.5
Guan, J.L.6
Mizushima, N.7
-
20
-
-
65249176304
-
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery
-
Jung, C. H., Jun, C. B., Ro, S. H., Kim, Y. M., Otto, N. M., Cao, J., Kundu, M., and Kim, D. H. (2009) ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Mol. Biol. Cell 20, 1992-2003
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 1992-2003
-
-
Jung, C.H.1
Jun, C.B.2
Ro, S.H.3
Kim, Y.M.4
Otto, N.M.5
Cao, J.6
Kundu, M.7
Kim, D.H.8
-
21
-
-
0036490552
-
Isolation and mass spectrometry of transcription factor complexes
-
Sebastiaan Winkler, G., Lacomis, L., Philip, J., Erdjument-Bromage, H., Svejstrup, J. Q., and Tempst, P. (2002) Isolation and mass spectrometry of transcription factor complexes. Methods 26, 260-269
-
(2002)
Methods
, vol.26
, pp. 260-269
-
-
Sebastiaan Winkler, G.1
Lacomis, L.2
Philip, J.3
Erdjument-Bromage, H.4
Svejstrup, J.Q.5
Tempst, P.6
-
22
-
-
0031784433
-
Examination of microtip reversed-phase liquid chromatographic extraction of peptide pools for mass spectrometric analysis
-
Erdjument-Bromage, H., Lui, M., Lacomis, L., Grewal, A., Annan, R. S., McNulty, D. E., Carr, S. A., and Tempst, P. (1998) Examination of microtip reversed-phase liquid chromatographic extraction of peptide pools for mass spectrometric analysis. J. Chromatogr. A. 826, 167-181
-
(1998)
J. Chromatogr. A
, vol.826
, pp. 167-181
-
-
Erdjument-Bromage, H.1
Lui, M.2
Lacomis, L.3
Grewal, A.4
Annan, R.S.5
McNulty, D.E.6
Carr, S.A.7
Tempst, P.8
-
23
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
Mali, P., Yang, L., Esvelt, K. M., Aach, J., Guell, M., DiCarlo, J. E., Norville, J. E., and Church, G. M. (2013) RNA-guided human genome engineering via Cas9. Science 339, 823-826
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali, P.1
Yang, L.2
Esvelt, K.M.3
Aach, J.4
Guell, M.5
DiCarlo, J.E.6
Norville, J.E.7
Church, G.M.8
-
24
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
Kim, J., Kundu, M., Viollet, B., and Guan, K. L. (2011) AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat. Cell Biol. 13, 132-141
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
25
-
-
79953211917
-
Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK
-
Shang, L., Chen, S., Du, F., Li, S., Zhao, L., and Wang, X. (2011) Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK. Proc. Natl. Acad. Sci. U.S.A. 108, 4788-4793
-
(2011)
Proc. Natl. Acad. Sci. U.S.A
, vol.108
, pp. 4788-4793
-
-
Shang, L.1
Chen, S.2
Du, F.3
Li, S.4
Zhao, L.5
Wang, X.6
-
26
-
-
79251587803
-
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
-
Egan, D. F., Shackelford, D. B., Mihaylova, M. M., Gelino, S., Kohnz, R. A., Mair, W., Vasquez, D. S., Joshi, A., Gwinn, D. M., Taylor, R., Asara, J. M., Fitzpatrick, J., Dillin, A., Viollet, B., Kundu, M., Hansen, M., and Shaw, R. J. (2011) Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy. Science 331, 456-461
-
(2011)
Science
, vol.331
, pp. 456-461
-
-
Egan, D.F.1
Shackelford, D.B.2
Mihaylova, M.M.3
Gelino, S.4
Kohnz, R.A.5
Mair, W.6
Vasquez, D.S.7
Joshi, A.8
Gwinn, D.M.9
Taylor, R.10
Asara, J.M.11
Fitzpatrick, J.12
Dillin, A.13
Viollet, B.14
Kundu, M.15
Hansen, M.16
Shaw, R.J.17
-
27
-
-
84873569898
-
Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy
-
Gammoh, N., Florey, O., Overholtzer, M., and Jiang, X. (2013) Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy. Nat. Struct. Mol. Biol. 20, 144-149
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 144-149
-
-
Gammoh, N.1
Florey, O.2
Overholtzer, M.3
Jiang, X.4
-
28
-
-
79960585318
-
Ammonia-induced autophagy is independent of ULK1/ULK2 kinases
-
Cheong, H., Lindsten, T., Wu, J., Lu, C., and Thompson, C. B. (2011) Ammonia-induced autophagy is independent of ULK1/ULK2 kinases. Proc. Natl. Acad. Sci. U.S.A. 108, 11121-11126
-
(2011)
Proc. Natl. Acad. Sci. U.S.A
, vol.108
, pp. 11121-11126
-
-
Cheong, H.1
Lindsten, T.2
Wu, J.3
Lu, C.4
Thompson, C.B.5
-
29
-
-
84928806944
-
Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy
-
Petherick, K. J., Conway, O. J., Mpamhanga, C., Osborne, S. A., Kamal, A., Saxty, B., and Ganley, I. G. (2015) Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy. J. Biol. Chem. 290, 11376-11383
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 11376-11383
-
-
Petherick, K.J.1
Conway, O.J.2
Mpamhanga, C.3
Osborne, S.A.4
Kamal, A.5
Saxty, B.6
Ganley, I.G.7
-
30
-
-
80051729441
-
Hsp90-Cdc37 chaperone complex regulates Ulk1- and Atg13-mediated mitophagy
-
Joo, J. H., Dorsey, F. C., Joshi, A., Hennessy-Walters, K. M., Rose, K. L., McCastlain, K., Zhang, J., Iyengar, R., Jung, C. H., Suen, D. F., Steeves, M. A., Yang, C. Y., Prater, S. M., Kim, D. H., Thompson, C. B., Youle, R. J., Ney, P. A., Cleveland, J. L., and Kundu, M. (2011) Hsp90-Cdc37 chaperone complex regulates Ulk1- and Atg13-mediated mitophagy. Mol. Cell 43, 572-585
-
(2011)
Mol. Cell
, vol.43
, pp. 572-585
-
-
Joo, J.H.1
Dorsey, F.C.2
Joshi, A.3
Hennessy-Walters, K.M.4
Rose, K.L.5
McCastlain, K.6
Zhang, J.7
Iyengar, R.8
Jung, C.H.9
Suen, D.F.10
Steeves, M.A.11
Yang, C.Y.12
Prater, S.M.13
Kim, D.H.14
Thompson, C.B.15
Youle, R.J.16
Ney, P.A.17
Cleveland, J.L.18
Kundu, M.19
-
31
-
-
84940550513
-
Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A
-
Wong, P. M., Feng, Y., Wang, J., Shi, R., and Jiang, X. (2015) Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A. Nat. Commun. 6, 8048
-
(2015)
Nat. Commun.
, vol.6
, pp. 8048
-
-
Wong, P.M.1
Feng, Y.2
Wang, J.3
Shi, R.4
Jiang, X.5
-
32
-
-
84948569863
-
AMPK and autophagy in glucose/glycogen metabolism
-
Ha, J., Guan, K. L., and Kim, J. (2015) AMPK and autophagy in glucose/glycogen metabolism. Mol. Aspects Med. 46, 46-62
-
(2015)
Mol. Aspects Med.
, vol.46
, pp. 46-62
-
-
Ha, J.1
Guan, K.L.2
Kim, J.3
-
33
-
-
84872586081
-
Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy
-
Kim, J., Kim, Y. C., Fang, C., Russell, R. C., Kim, J. H., Fan, W., Liu, R., Zhong, Q., and Guan, K. L. (2013) Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy. Cell 152, 290-303
-
(2013)
Cell
, vol.152
, pp. 290-303
-
-
Kim, J.1
Kim, Y.C.2
Fang, C.3
Russell, R.C.4
Kim, J.H.5
Fan, W.6
Liu, R.7
Zhong, Q.8
Guan, K.L.9
|