Reconstitution of biosynthetic machinery of fungal polyketides: Unexpected oxidations of biosynthetic intermediates by expression host

Bioscience, Biotechnology and Biochemistry

Volumn 80, Issue 3, 2016, Pages 426-431

  Fujii, Ryuya ^a   Ugai, Takahiro ^a   Ichinose, Hirofumi ^b   Hatakeyama, Mayumi ^b   Kosaki, Takuto ^a   Gomi, Katsuya ^c   Fujii, Isao ^d   Minami, Atsushi ^a   Oikawa, Hideaki ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

^d IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

Aspergillus oryzae; Biosynthesis; Heterologous expression; Solanapyrone; Cytochalasin

Indexed keywords

ASPERGILLUS; BIOCHEMISTRY; ENZYMES; FUNGI; GENES; MACHINERY;

ASPERGILLUS ORYZAE; BIOSYNTHETIC GENE; CYTOCHALASIN; FUNGAL METABOLITES; HETEROLOGOUS EXPRESSION; HETEROLOGOUS PRODUCTION; NATURAL PRODUCTS; STRUCTURE DETERMINATION;

BIOSYNTHESIS;

POLYKETIDE;

ASPERGILLUS ORYZAE; CARBON NUCLEAR MAGNETIC RESONANCE; ELECTROSPRAY MASS SPECTROMETRY; FUNGAL GENE; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; OXIDATION REDUCTION REACTION; PROTON NUCLEAR MAGNETIC RESONANCE;

ASPERGILLUS ORYZAE; CARBON-13 MAGNETIC RESONANCE SPECTROSCOPY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GENES, FUNGAL; OXIDATION-REDUCTION; POLYKETIDES; PROTON MAGNETIC RESONANCE SPECTROSCOPY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84958969981     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1080/09168451.2015.1104234     Document Type: Article

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