Evolutionarily conserved primary TNF sequences relate to its primitive functions in cell death induction

Journal of Cell Science

Volumn 129, Issue 1, 2016, Pages 108-120

  Lu, Wenshu ^a   Chen, Qiongyu ^a   Ying, Songmin ^a   Xia, Xiaobing ^a   Yu, Zhanru ^b   Lui, Yuan ^b   Tranter, George ^c   Jin, Boquan ^d   Song, Chaojun ^d   Seymour, Leonard W ^a   Jiang, Shisong ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c Chiralabs Limited   (United Kingdom)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Evolution; Necrosis; NF B; Overlapping peptides; TNF

Indexed keywords

CASPASE 8; FAS ASSOCIATED DEATH DOMAIN PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY P1213; MUTANT PROTEIN; PEPTIDE; PEPTIDE P12; PEPTIDE P1213; PEPTIDE P13; PEPTIDE P14; PEPTIDE P15; PEPTIDE P1516; PEPTIDE P16; PROTEIN; PROTEIN RIP1; SUCCINATE DEHYDROGENASE (UBIQUINONE); TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED DEATH DOMAIN PROTEIN; UNCLASSIFIED DRUG; AGFG1 PROTEIN, HUMAN; FADD PROTEIN, HUMAN; NUCLEOPORIN; RNA BINDING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL DEATH; CELL MEMBRANE; CIRCULAR DICHROISM; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; MEMBRANE DAMAGE; MOUSE; NECROSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; CONSERVED SEQUENCE; DRUG EFFECTS; JURKAT CELL LINE; METABOLISM; MOLECULAR EVOLUTION; MOLECULAR GENETICS; VERTEBRATE;

AMINO ACID SEQUENCE; ANIMALS; CASPASE 8; CELL MEMBRANE; CONSERVED SEQUENCE; EVOLUTION, MOLECULAR; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HUMANS; JURKAT CELLS; MICE; MOLECULAR SEQUENCE DATA; NUCLEAR PORE COMPLEX PROTEINS; PEPTIDES; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RNA-BINDING PROTEINS; TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN; TUMOR NECROSIS FACTOR-ALPHA; VERTEBRATES;

EID: 84958966090     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.175463     Document Type: Article

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