Role for Daple in non-canonical Wnt signaling during gastric cancer invasion and metastasis

Cancer Science

Volumn 107, Issue 2, 2016, Pages 133-139

  Ara, Hosne ^a   Takagishi, Maki ^a   Enomoto, Atsushi ^a   Asai, Masato ^a   Ushida, Kaori ^a   Asai, Naoya ^a   Shimoyama, Yoshie ^b   Kaibuchi, Kozo ^a   Kodera, Yasuhiro ^a   Takahashi, Masahide ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY HOSPITAL   (Japan)

Author keywords

Daple; Gastric cancer; Invasion; Metastasis; Wnt signaling

Indexed keywords

DAPLE; JANUS KINASE; LAMININ; PROTEIN DERIVATIVE; RAC PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN; ACTIN BINDING PROTEIN; CCDC88C PROTEIN, HUMAN; SIGNAL PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GROWTH; CELL MIGRATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER METASTASIS; LYMPH NODE METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STOMACH CANCER; TUMOR INVASION; ANIMAL; CELL MOTION; GENE SILENCING; IMMUNOHISTOCHEMISTRY; METABOLISM; METASTASIS; NUDE MOUSE; PATHOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH TUMOR; WESTERN BLOTTING; WNT SIGNALING PATHWAY; XENOGRAFT;

ANIMALS; BLOTTING, WESTERN; CELL MOVEMENT; GENE KNOCKDOWN TECHNIQUES; HETEROGRAFTS; HUMANS; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, NUDE; MICROFILAMENT PROTEINS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STOMACH NEOPLASMS; WNT SIGNALING PATHWAY;

EID: 84958881809     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/cas.12848     Document Type: Article

References (38)

1. Ferlay J, Soerjomataram I, Dikshit R et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 2015; 136: E359-86.
2. Deng N, Goh LK, Wang H et al. A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets. Gut 2012; 61: 673-84.
3. Yang W, Raufi A, Klempner SJ. Targeted therapy for gastric cancer: molecular pathways and ongoing investigations. Biochim Biophys Acta 2014; 1846: 232-7.
4. El-Rifai W, Powell SM. Molecular biology of gastric cancer. Semin Radiat Oncol 2002; 12: 128-40.
5. Gotoda T, Yanagisawa A, Sasako M et al. Incidence of lymph node metastasis from early gastric cancer: estimation with a large number of cases at two large centers. Gastric Cancer 2000; 3: 219-25.
6. Katoh M. Dysregulation of stem cell signaling network due to germline mutation, SNP, Helicobacter pylori infection, epigenetic change and genetic alteration in gastric cancer. Cancer Biol Ther 2007; 6: 832-9.
7. Giles RH, van Es JH, Clevers H. Caught up in a Wnt storm: Wnt signaling in cancer. Biochim Biophys Acta 2003; 1653: 1-24.
8. Logan CY, Nusse R. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 2004; 20: 781-810.
9. Anastas JN, Moon RT. WNT signalling pathways as therapeutic targets in cancer. Nat Rev Cancer 2013; 13: 11-26.
10. Clevers H. Wnt/β-catenin signaling in development and disease. Cell 2006; 127: 469-80.
11. Kikuchi A. Tumor formation by genetic mutations in the components of the Wnt signaling pathway. Cancer Sci 2003; 94: 225-9.
12. Polakis P. The many ways of Wnt in cancer. Curr Opin Genet Dev 2007; 17: 45-51.
13. Habas R, Dawid IB, He X. Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation. Genes Dev 2003; 17: 295-309.
14. Veeman MT, Axelrod JD, Moon RT. A second canon: functions and mechanisms of β-catenin-independent Wnt signalling. Dev Cell 2003; 5: 367-77.
15. Kikuchi A, Yamamoto H, Sato A, Matsumoto S. Wnt5a: its signalling, functions and implication in diseases. Acta Physiol (Oxf) 2012; 204: 17-33.
16. Kurayoshi M, Oue N, Yamamoto H et al. Expression of Wnt-5a is correlated with aggressiveness of gastric cancer by stimulating cell migration and invasion. Cancer Res 2006; 66: 10439-48.
17. Yamamoto H, Kitadai Y, Yamamoto H et al. Laminin γ2 mediates Wnt5a-induced invasion of gastric cancer cells. Gastroenterology 2009; 137: 242-52.
18. Hanaki H, Yamamoto H, Sakane H et al. An anti-Wnt5a antibody suppresses metastasis of gastric cancer cells in vivo by inhibiting receptor-mediated endocytosis. Mol Cancer Ther 2012; 11: 298-307.
19. Miyazaki K. Laminin-5 (laminin-332): unique biological activity and role in tumor growth and invasion. Cancer Sci 2006; 97: 91-8.
20. Koshikawa N, Moriyama K, Takamura H et al. Overexpression of laminin γ2 chain monomer in invading gastric carcinoma cells. Cancer Res 1999; 59: 5596-601.
21. Oshita A, Kishida S, Kobayashi H et al. Identification and characterization of a novel Dvl-binding protein that suppresses Wnt signalling pathway. Genes Cells 2003; 8: 1005-17.
22. Ishida-Takagishi M, Enomoto A, Asai N et al. The Disheveled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility. Nat Commun 2012; 3: 859.
23. Kobayashi H, Michiue T, Yukita A et al. Novel Daple-like protein positively regulates both the Wnt/β-catenin pathway and the Wnt/JNK pathway in Xenopus. Mech Dev 2005; 122: 1138-53.
24. Tsoi H, Yu AC, Chen ZS et al. A novel missense mutation in CCDC88C activates the JNK pathway and causes a dominant form of spinocerebellar ataxia. J Med Genet 2014; 51: 590-5.
25. Lauren P. The two histological main types of gastric carcinoma, an attempt at a histoclinical classification. Acta Pathol Microbiol Scand. 1965; 64: 31-49.
26. Shiroshita H, Watanabe H, Ajioka Y, Watanabe G, Nishikura K, Kitano S. Re-evaluation of mucin phenotypes of gastric minute well-differentiated-type adenocarcinomas using a series of HGM, MUC5AC, MUC6, M-GGMC, MUC2 and CD10 stains. Pathol Int 2004; 54: 311-21.
27. Mizoshita T, Tsukamoto T, Nakanishi H et al. Expression of Cdx2 and the phenotype of advanced gastric cancers: relationship with prognosis. J Cancer Res Clin Oncol 2003; 129: 727-34.
28. Shimoyama Y, Hirohashi S. Expression of E-and P-cadherin in gastric carcinomas. Cancer Res 1991; 51: 2185-92.
29. Enomoto A, Asai N, Namba T et al. Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus. Neuron 2009; 63: 774-87.
30. Allred DC, Harvey JM, Berardo M, Clark GM. Prognostic and predictive factors in breast cancer by immunohistochemical analysis. Mod Pathol 1998; 11: 155-68.
31. Woo DK, Kim HS, Lee HS, Kang YH, Yang HK, Kim WH. Altered expression and mutation of β-catenin gene in gastric carcinomas and cell lines. Int J Cancer 2001; 95: 108-13.
32. Tsuchiya Y, Sato H, Endo Y et al. Tissue inhibitor of metalloproteinase 1 is a negative regulator of the metastatic ability of a human gastric cancer cell line, KKLS, in the chick embryo. Cancer Res 1993; 53: 1397-402.
33. Shah MA, Ajani JA. Gastric cancer-An enigmatic and heterogeneous disease. JAMA 2010; 303: 1753-4.
34. Grote D, Boualia SK, Souabni A et al. Gata3 acts downstream of β-catenin signaling to prevent ectopic metanephric kidney induction. PLoS Genet 2008; 4: e1000316.
35. Li G, Ruan X, Auerbach RK et al. Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation. Cell 2012; 148: 84-98.
36. Takano N, Iizuka N, Hazama S, Yoshino S, Tangoku A, Oka M. Expression of estrogen receptor-α and-β mRNAs in human gastric cancer. Cancer Lett 2002; 176: 129-35.
37. Pyke C, Salo S, Ralfkiaer E, Rømer J, Danø K, Tryggvason K. Laminin-5 is a marker of invading cancer cells in some human carcinomas and is coexpressed with the receptor for urokinase plasminogen activator in budding cancer cells in colon adenocarcinomas. Cancer Res 1995; 55: 4132-9.
38. Aznar N, Midde KK, Dunkel Y et al. Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling. Elife 2015; 4: e07091.