New tools for chloroplast genetic engineering allow the synthesis of human growth hormone in the green alga Chlamydomonas reinhardtii

Applied Microbiology and Biotechnology

Volumn 100, Issue 12, 2016, Pages 5467-5477

  Wannathong, Thanyanan ^b   Waterhouse, Janet C ^a   Young, Rosanna E B ^a   Economou, Chloe K ^a   Purton, Saul ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b SILPAKORN UNIVERSITY   (Thailand)

Author keywords

Chlamydomonas; Chloroplast; Genetic engineering; Human growth hormone

Indexed keywords

BIOSYNTHESIS; DRUG THERAPY; GENE EXPRESSION; GENETIC ENGINEERING; PLANTS (BOTANY); PROTEINS; RECOMBINANT PROTEINS;

ANTIBIOTIC RESISTANCE; CHLAMYDOMONAS; CHLAMYDOMONAS REINHARDTII; CHLOROPLAST; CHLOROPLAST GENETIC ENGINEERINGS; HUMAN GROWTH HORMONE; INDUSTRIAL BIOTECHNOLOGY; THERAPEUTIC PROTEIN;

GENES;

ALGAL DNA; HUMAN GROWTH HORMONE;

ANTIBIOTIC RESISTANCE; CHLOROPLAST; GENE; GENE EXPRESSION; GENETIC ENGINEERING; GENETIC MARKER; GREEN ALGA; HORMONE; METABOLITE;

5' UNTRANSLATED REGION; ARTICLE; ATPA GENE; CELL SUSPENSION; CHLAMYDOMONAS REINHARDTII; CHLOROPLAST; CHLOROPLAST GENETICS; CONTROLLED STUDY; ESCHERICHIA COLI; EXPRESSION VECTOR; GENE CONSTRUCT; GENE INSERTION; GENETIC ENGINEERING; GENETIC TRANSFORMATION; GLASS BEAD TRANSFORMATION METHOD; HORMONE SYNTHESIS; MARKER GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOTOTROPHY; PROMOTER REGION; PSAA GENE; PSBH GENE; TRANSFORMED CELL; TRANSGENE; TRANSGENICS; BIOSYNTHESIS; GENE VECTOR; GENETICS; HUMAN; METABOLISM; PROCEDURES;

ALGAE; CHLAMYDOMONAS; CHLAMYDOMONAS REINHARDTII; CHLOROPHYTA; EUKARYOTA;

CHLAMYDOMONAS REINHARDTII; CHLOROPLASTS; GENETIC ENGINEERING; GENETIC VECTORS; HUMAN GROWTH HORMONE; HUMANS; PROMOTER REGIONS, GENETIC; TRANSFORMATION, GENETIC; TRANSGENES;

EID: 84958780096     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-016-7354-6     Document Type: Article

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