Expression and assembly of a fully active antibody in algae

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 2, 2003, Pages 438-442

  Mayfield, Stephen P ^a   Franklin, Scott E ^a   Lerner, Richard A ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; GLYCOPROTEIN D; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN HEAVY CHAIN;

ALGAL GROWTH; ANTIBODY PRODUCTION; ARTICLE; CHLAMYDOMONAS REINHARDTII; COMBINATORIAL LIBRARY; DIMERIZATION; DISULFIDE BOND; GENE EXPRESSION; GREEN ALGA; HERPES SIMPLEX VIRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN MODIFICATION;

ALGAE, GREEN; AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; BLOTTING, SOUTHERN; CHLOROPLASTS; ESCHERICHIA COLI; HUMANS; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; RNA, MESSENGER; TRANSGENES;

ALGAE; CHLAMYDOMONAS; CHLAMYDOMONAS REINHARDTII; CHLOROPHYTA; SIMPLEXVIRUS;

EID: 0037457888     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0237108100     Document Type: Article

References (22)

1. Dove, A. (2002) Nat. Biotechnol. 20, 777-779.
2. Motmans, K. & Bouche, B. (2000) Antibodies: The Next Generation (Auerbach Grayson, New York).
3. Hiatt, A., Cafferky, R. & Bowdish, K. (1989) Nature 342, 76-78.
4. Ma, J., Lehner, T., Stabila, P., Fux, C. I. & Hiatt, A. (1994) Eur. J. Immunol. 24, 131-138.
5. Ma, J., Hiatt, A., Hein, M., Vine, N. D., Wang, F., Satabila, P., van Dollweerd, C., Mostov, K. & Lehner, T. (1995) Science 268, 716-719.
6. Ellstrand, N. C. (2001) Plant Physiol. 125, 1543-1545.
7. Quist, D. & Chapela, I. (2001) Nature 414, 541-543.
8. Staub, J. M., Garcia, B., Graves, J., Hajdukiewicz, P. T., Hunter, P., Nehra, N., Paradkar, V., Schlittler, M., Carroll, J. A., Spatola, L., et al. (2000) Nat. Biotechnol. 18, 333-338.
9. Kota, M., Daniell, H., Varma, S., Garczynski, S. F., Gould, F. & Moar, W. J. (1999) Proc. Natl. Acad. Sci. USA 96, 1840-1845.
10. Sidrov, V. A., Kasten, D., Pang, S. Z., Hajdukiewwicz, P. T., Staub, J. M. & Nehra, N. S. (1999) Plant J. 19, 209-216.
11. Ruf, S., Herrmann, M., Berger, I., Carrer, I. J. & Bock, R. (2001) Nat. Biotechnol. 19, 870-875.
12. Heifetz, P. B. (2000) Biochimie 82, 655-666.
13. Harris, E. (1989) The Chlamydomonas Sourcebook (Academic, New York).
14. Franklin, S. E., Ngo, B., Effuet, E. & Mayfield, S. P. (2002) Plant J. 30, 733-744.
15. Burioni, R., Williamson, R. A., Sanna, P. P., Bloom, F. E. & Burton, D. R. (1994) Proc. Natl. Acad. Sci. USA 91, 355-359.
16. Gorman, D. S. & Levine, R. P. (1965) Proc. Natl. Acad. Sci. USA 54, 1665-1669.
17. Sambrook, J., Fritsch, E. F. & Maniatas, T. (1989) Molecular Cloning: A Laboratory Manual (Cold Spring Harbor Lab. Press, Plainview, NY).
18. Cohen, A., Yohn, C. B., Bruick, R. K. & Mayfield, S. P. (1998) Methods Enzymol. 297, 192-208.
19. Stemmer, W., Crameri, A., Ha, K., Brennan, T. & Heyneker, H. (1995) Gene 164, 49-53.
20. De Logu, A., Williamson, R. A., Rozenshteyn, R., Ramiro-Ibanez, F., Simpson, C. D., Burton, D. R. & Sanna, P. P. (1998) J. Clin. Microbiol. 36, 3198-3204.
21. Boynton, J. E., Gillham, N. W., Harris, E. H., Hosler, J. P., Johnson, A. M., Jones, A. R., Randolph-Anderson, B. L., Robertson, D., Klein, T. M., Shark, K. B. & Sanford, J. C. (1988) Science 240, 1534-1538.
22. Kim, J. & Mayfield, S. P. (1997) Science 278, 1954-1957.