High-yield production of a human therapeutic protein in tobacco chloroplasts

Nature Biotechnology

Volumn 18, Issue 3, 2000, Pages 333-338

  Staub, Jeffrey M ^a   Garcia, Bradley ^a   Graves, Julie ^a   Hajdukiewicz, Peter T J ^a   Hunter, Priscilla ^a   Nehra, Narender ^a   Paradkar, Vikram ^a   Schlittler, Michael ^a   Carroll, James A ^a   Spatola, Lori ^a   Ward, Dannette ^a   Ye, Guangning ^a   Russell, Douglas A ^a  

^a MONSANTO COMPANY   (United States)

Author keywords

Pharmaceutical; Plastid transformation; Somatotropin; Transplastomic; Ubiquitin fusion

Indexed keywords

HUMAN GROWTH HORMONE; RECOMBINANT PROTEIN; SECRETORY PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CHLOROPLAST; CONTROLLED STUDY; FEASIBILITY STUDY; GENE EXPRESSION; GENE LOCATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; RECOMBINANT DNA TECHNOLOGY; TOBACCO; TRANSGENIC PLANT;

BLOTTING, WESTERN; CELL DIVISION; CELL LINE; CHLOROPLASTS; DISULFIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; GENETIC ENGINEERING; GENOME, PLANT; HUMAN GROWTH HORMONE; HUMANS; PLANTS, GENETICALLY MODIFIED; PLANTS, TOXIC; PLASTIDS; RECOMBINANT PROTEINS; TOBACCO;

MAMMALIA; NICOTIANA TABACUM;

EID: 0034016818     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/73796     Document Type: Article

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