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Volumn 30, Issue 2, 2016, Pages 635-652

DMP-1-mediated Ghr gene recombination compromises skeletal development and impairs skeletal response to intermittent PTH

Author keywords

Fibroblast growth factor 23; Growth hormone receptor; Microcomputed tomography; Osteocyte; Parathyroid hormone

Indexed keywords

DENTIN MATRIX PROTEIN 1; GROWTH HORMONE; JANUS KINASE 2; PARATHYROID HORMONE; PHOSPHATE; SOMATOMEDIN C; CARRIER PROTEIN; DMP1 PROTEIN, MOUSE; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 23; PHOSPHORUS; SCLEROPROTEIN; SOMATOTROPIN-BINDING PROTEIN;

EID: 84958767726     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.15-275859     Document Type: Article
Times cited : (21)

References (70)
  • 1
    • 76649123607 scopus 로고    scopus 로고
    • Osteoporosis: Impact on health and economics
    • Harvey, N., Dennison, E., and Cooper, C. (2010) Osteoporosis: impact on health and economics. Nat. Rev. Rheumatol. 6, 99-105
    • (2010) Nat. Rev. Rheumatol , vol.6 , pp. 99-105
    • Harvey, N.1    Dennison, E.2    Cooper, C.3
  • 2
    • 84856783815 scopus 로고    scopus 로고
    • Update on bone anabolics in osteoporosis treatment: Rationale, current status, and perspectives
    • Baron, R., and Hesse, E. (2012) Update on bone anabolics in osteoporosis treatment: rationale, current status, and perspectives. J. Clin. Endocrinol. Metab. 97, 311-325
    • (2012) J. Clin. Endocrinol. Metab , vol.97 , pp. 311-325
    • Baron, R.1    Hesse, E.2
  • 3
    • 84880562766 scopus 로고    scopus 로고
    • Pathogenesis of age-related bone loss in humans
    • Khosla, S. (2013) Pathogenesis of age-related bone loss in humans. J. Gerontol. A Biol. Sci. Med. Sci. 68, 1226-1235
    • (2013) J. Gerontol. A Biol. Sci. Med. Sci , vol.68 , pp. 1226-1235
    • Khosla, S.1
  • 5
    • 0031787356 scopus 로고    scopus 로고
    • Familial resemblance for bone mineral mass is expressed before puberty
    • Ferrari, S., Rizzoli, R., Slosman, D., and Bonjour, J. P. (1998) Familial resemblance for bone mineral mass is expressed before puberty. J. Clin. Endocrinol. Metab. 83, 358-361
    • (1998) J. Clin. Endocrinol. Metab , vol.83 , pp. 358-361
    • Ferrari, S.1    Rizzoli, R.2    Slosman, D.3    Bonjour, J.P.4
  • 7
    • 6344263668 scopus 로고    scopus 로고
    • Southampton Genetic Epidemiology Research Group. 2004 Polymorphism in the growth hormone gene, weight in infancy, and adult bonemass
    • Dennison, E. M., Syddall, H. E., Rodriguez, S., Voropanov, A., Day, I.N., and Cooper, C.; Southampton Genetic Epidemiology Research Group. (2004) Polymorphism in the growth hormone gene, weight in infancy, and adult bonemass. J. Clin. Endocrinol. Metab. 89, 4898-4903
    • J. Clin. Endocrinol. Metab , vol.89 , pp. 4898-4903
    • Dennison, E.M.1    Syddall, H.E.2    Rodriguez, S.3    Voropanov, A.4    Day, I.N.5    Cooper, C.6
  • 9
    • 79251493453 scopus 로고    scopus 로고
    • The amazing osteocyte
    • Bonewald, L. F. (2011) The amazing osteocyte. J. BoneMiner. Res. 26, 229-238
    • (2011) J. BoneMiner. Res , vol.26 , pp. 229-238
    • Bonewald, L.F.1
  • 11
    • 0036251217 scopus 로고    scopus 로고
    • Parathyroid hormone is essential for normal fetal bone formation
    • Miao, D., He, B., Karaplis, A. C., and Goltzman, D. (2002) Parathyroid hormone is essential for normal fetal bone formation. J. Clin. Invest. 109, 1173-1182
    • (2002) J. Clin. Invest , vol.109 , pp. 1173-1182
    • Miao, D.1    He, B.2    Karaplis, A.C.3    Goltzman, D.4
  • 12
    • 20444472774 scopus 로고    scopus 로고
    • Genetic models show that parathyroid hormone and 1, 25- dihydroxyvitamin D3 play distinct and synergistic roles in postnatal mineral ion homeostasis and skeletal development
    • Xue, Y., Karaplis, A. C., Hendy, G. N., Goltzman, D., and Miao, D. (2005) Genetic models show that parathyroid hormone and 1, 25- dihydroxyvitamin D3 play distinct and synergistic roles in postnatal mineral ion homeostasis and skeletal development. Hum. Mol. Genet. 14, 1515-1528
    • (2005) Hum. Mol. Genet , vol.14 , pp. 1515-1528
    • Xue, Y.1    Karaplis, A.C.2    Hendy, G.N.3    Goltzman, D.4    Miao, D.5
  • 13
    • 79953701946 scopus 로고    scopus 로고
    • Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses
    • Powell, W. F., Jr., Barry, K. J., Tulum, I., Kobayashi, T., Harris, S. E., Bringhurst, F. R., and Pajevic, P. D. (2011) Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses. J. Endocrinol. 209, 21-32
    • (2011) J. Endocrinol , vol.209 , pp. 21-32
    • Powell, W.F.1    Barry, K.J.2    Tulum, I.3    Kobayashi, T.4    Harris, S.E.5    Bringhurst, F.R.6    Pajevic, P.D.7
  • 14
    • 84880072246 scopus 로고    scopus 로고
    • Parathyroid hormone (PTH)/PTH-related peptide type 1 receptor (PPR) signaling in osteocytes regulates anabolic and catabolic skeletal responses to PTH
    • Saini, V., Marengi, D.A., Barry, K. J., Fulzele, K. S., Heiden, E., Liu, X., Dedic, C., Maeda, A., Lotinun, S., Baron, R., and Pajevic, P.D.(2013) Parathyroid hormone (PTH)/PTH-related peptide type 1 receptor (PPR) signaling in osteocytes regulates anabolic and catabolic skeletal responses to PTH. J. Biol. Chem. 288, 20122-20134
    • (2013) J. Biol. Chem , vol.288 , pp. 20122-20134
    • Saini, V.1    Marengi, D.A.2    Barry, K.J.3    Fulzele, K.S.4    Heiden, E.5    Liu, X.6    Dedic, C.7    Maeda, A.8    Lotinun, S.9    Baron, R.10    Pajevic, P.D.11
  • 15
    • 0029165931 scopus 로고
    • Parathyroid hormone increases the concentration of insulin-like growth factor-I and transforming growth factor beta 1 in rat bone
    • Pfeilschifter, J., Laukhuf, F., Müller-Beckmann, B., Blum, W. F., Pfister, T., and Ziegler, R. (1995) Parathyroid hormone increases the concentration of insulin-like growth factor-I and transforming growth factor beta 1 in rat bone. J. Clin. Invest. 96, 767-774
    • (1995) J. Clin. Invest , vol.96 , pp. 767-774
    • Pfeilschifter, J.1    Laukhuf, F.2    Müller-Beckmann, B.3    Blum, W.F.4    Pfister, T.5    Ziegler, R.6
  • 16
    • 0029127979 scopus 로고
    • Parathyroid hormone restores bone mass and enhances osteoblast insulin-like growth factor i gene expression in ovariectomized rats
    • Watson, P., Lazowski, D., Han, V., Fraher, L., Steer, B., and Hodsman, A. (1995) Parathyroid hormone restores bone mass and enhances osteoblast insulin-like growth factor I gene expression in ovariectomized rats. Bone 16, 357-365
    • (1995) Bone , vol.16 , pp. 357-365
    • Watson, P.1    Lazowski, D.2    Han, V.3    Fraher, L.4    Steer, B.5    Hodsman, A.6
  • 19
    • 0034807415 scopus 로고    scopus 로고
    • Evidence that anabolic effects of PTH on bone require IGF-I in growing mice
    • Miyakoshi, N., Kasukawa, Y., Linkhart, T. A., Baylink, D. J., and Mohan, S. (2001) Evidence that anabolic effects of PTH on bone require IGF-I in growing mice. Endocrinology 142, 4349-4356
    • (2001) Endocrinology , vol.142 , pp. 4349-4356
    • Miyakoshi, N.1    Kasukawa, Y.2    Linkhart, T.A.3    Baylink, D.J.4    Mohan, S.5
  • 22
    • 80054979878 scopus 로고    scopus 로고
    • Cell line IDG-SW3 replicates osteoblast-to-late-osteocyte differentiation in vitro and accelerates bone formation in vivo
    • Woo, S. M., Rosser, J., Dusevich, V., Kalajzic, I., and Bonewald, L. F. (2011) Cell line IDG-SW3 replicates osteoblast-to-late-osteocyte differentiation in vitro and accelerates bone formation in vivo. J. Bone Miner. Res. 26, 2634-2646
    • (2011) J. Bone Miner. Res , vol.26 , pp. 2634-2646
    • Woo, S.M.1    Rosser, J.2    Dusevich, V.3    Kalajzic, I.4    Bonewald, L.F.5
  • 26
  • 28
    • 84555195115 scopus 로고    scopus 로고
    • Targeted loss of GHR signaling in mouse skeletal muscle protects against high-fat dietinduced metabolic deterioration
    • Vijayakumar, A., Wu, Y., Sun, H., Li, X., Jeddy, Z., Liu, C., Schwartz, G. J., Yakar, S., and LeRoith, D. (2012) Targeted loss of GHR signaling in mouse skeletal muscle protects against high-fat dietinduced metabolic deterioration. Diabetes 61, 94-103
    • (2012) Diabetes , vol.61 , pp. 94-103
    • Vijayakumar, A.1    Wu, Y.2    Sun, H.3    Li, X.4    Jeddy, Z.5    Liu, C.6    Schwartz, G.J.7    Yakar, S.8    LeRoith, D.9
  • 29
    • 79957887666 scopus 로고    scopus 로고
    • Growth hormone receptor regulates b cell hyperplasia and glucosestimulated insulin secretion in obese mice
    • Wu, Y., Liu, C., Sun, H., Vijayakumar, A., Giglou, P. R., Qiao, R., Oppenheimer, J., Yakar, S., and LeRoith, D. (2011) Growth hormone receptor regulates b cell hyperplasia and glucosestimulated insulin secretion in obese mice. J. Clin. Invest. 121, 2422-2426
    • (2011) J. Clin. Invest , vol.121 , pp. 2422-2426
    • Wu, Y.1    Liu, C.2    Sun, H.3    Vijayakumar, A.4    Giglou, P.R.5    Qiao, R.6    Oppenheimer, J.7    Yakar, S.8    LeRoith, D.9
  • 30
    • 84884681085 scopus 로고    scopus 로고
    • Deletion of growth hormone receptors in postnatal skeletal muscle of male mice does not alter muscle mass and response to pathological injury
    • Vijayakumar, A., Buffin, N. J., Gallagher, E. J., Blank, J., Wu, Y., Yakar, S., and LeRoith, D. (2013)Deletion of growth hormone receptors in postnatal skeletal muscle of male mice does not alter muscle mass and response to pathological injury. Endocrinology 154, 3776-3783
    • (2013) Endocrinology , vol.154 , pp. 3776-3783
    • Vijayakumar, A.1    Buffin, N.J.2    Gallagher, E.J.3    Blank, J.4    Wu, Y.5    Yakar, S.6    LeRoith, D.7
  • 31
    • 84866396334 scopus 로고    scopus 로고
    • Skeletal muscle growth hormone receptor signaling regulates basal, but not fasting-induced, lipid oxidation
    • Vijayakumar, A., Wu, Y., Buffin, N. J., Li, X., Sun, H., Gordon, R. E., Yakar, S., and LeRoith, D. (2012) Skeletal muscle growth hormone receptor signaling regulates basal, but not fasting-induced, lipid oxidation. PLoS One 7, e44777
    • (2012) PLoS One , vol.7 , pp. e44777
    • Vijayakumar, A.1    Wu, Y.2    Buffin, N.J.3    Li, X.4    Sun, H.5    Gordon, R.E.6    Yakar, S.7    LeRoith, D.8
  • 32
    • 84903960656 scopus 로고    scopus 로고
    • Role of osteocytederived insulin-like growth factor i in developmental growth, modeling, remodeling, and regeneration of the bone
    • Sheng, M.H., Lau, K.H., and Baylink, D. J. (2014) Role of osteocytederived insulin-like growth factor I in developmental growth, modeling, remodeling, and regeneration of the bone. J. Bone Metab. 21, 41-54
    • (2014) J. Bone Metab , vol.21 , pp. 41-54
    • Sheng, M.H.1    Lau, K.H.2    Baylink, D.J.3
  • 33
    • 84867477893 scopus 로고    scopus 로고
    • Disruption of the insulin-like growth factor-1 gene in osteocytes impairs developmental bone growth in mice
    • Sheng, M. H., Zhou, X. D., Bonewald, L. F., Baylink, D. J., and Lau, K. H. (2013) Disruption of the insulin-like growth factor-1 gene in osteocytes impairs developmental bone growth in mice. Bone 52, 133-144
    • (2013) Bone , vol.52 , pp. 133-144
    • Sheng, M.H.1    Zhou, X.D.2    Bonewald, L.F.3    Baylink, D.J.4    Lau, K.H.5
  • 34
    • 77957993384 scopus 로고    scopus 로고
    • PTH increases FGF23 gene expression and mediates the high-FGF23 levels of experimental kidney failure: A bone parathyroid feedback loop
    • Lavi-Moshayoff, V., Wasserman, G., Meir, T., Silver, J., and Naveh-Many, T. (2010) PTH increases FGF23 gene expression and mediates the high-FGF23 levels of experimental kidney failure: a bone parathyroid feedback loop. Am. J. Physiol. Renal Physiol. 299, F882-F889
    • (2010) Am. J. Physiol. Renal Physiol , vol.299 , pp. F882-F889
    • Lavi-Moshayoff, V.1    Wasserman, G.2    Meir, T.3    Silver, J.4    Naveh-Many, T.5
  • 35
    • 34948866160 scopus 로고    scopus 로고
    • Parathyroid hormone regulates fibroblast growth factor-23 in amousemodel of primary hyperparathyroidism
    • Kawata, T., Imanishi, Y., Kobayashi, K., Miki, T., Arnold, A., Inaba, M., and Nishizawa, Y. (2007) Parathyroid hormone regulates fibroblast growth factor-23 in amousemodel of primary hyperparathyroidism. J. Am. Soc. Nephrol. 18, 2683-2688
    • (2007) J. Am. Soc. Nephrol , vol.18 , pp. 2683-2688
    • Kawata, T.1    Imanishi, Y.2    Kobayashi, K.3    Miki, T.4    Arnold, A.5    Inaba, M.6    Nishizawa, Y.7
  • 37
    • 0035186731 scopus 로고    scopus 로고
    • Local IGF-I expressionand bone formation
    • McCarthy, T.L., and Centrella, M. (2001)Local IGF-I expressionand bone formation. Growth Horm. IGF Res. 11, 213-219
    • (2001) Growth Horm. IGF Res , vol.11 , pp. 213-219
    • McCarthy, T.L.1    Centrella, M.2
  • 38
  • 41
    • 77956832787 scopus 로고    scopus 로고
    • Elevated serum IGF-1 levels synergize PTH action on the skeleton only when the tissue IGF-1 axis is intact
    • Elis, S., Courtland, H. W., Wu, Y., Fritton, J. C., Sun, H., Rosen, C. J., and Yakar, S. (2010) Elevated serum IGF-1 levels synergize PTH action on the skeleton only when the tissue IGF-1 axis is intact. J. Bone Miner. Res. 25, 2051-2058
    • (2010) J. Bone Miner. Res , vol.25 , pp. 2051-2058
    • Elis, S.1    Courtland, H.W.2    Wu, Y.3    Fritton, J.C.4    Sun, H.5    Rosen, C.J.6    Yakar, S.7
  • 42
    • 77953481694 scopus 로고    scopus 로고
    • Elevated serumlevels of IGF-1 are sufficient to establish normal body size and skeletal properties even in the absence of tissue IGF-1
    • Elis, S., Courtland, H. W., Wu, Y., Rosen, C. J., Sun, H., Jepsen, K. J., Majeska, R. J., and Yakar, S. (2010) Elevated serumlevels of IGF-1 are sufficient to establish normal body size and skeletal properties even in the absence of tissue IGF-1. J. Bone Miner. Res. 25, 1257-1266
    • (2010) J. Bone Miner. Res , vol.25 , pp. 1257-1266
    • Elis, S.1    Courtland, H.W.2    Wu, Y.3    Rosen, C.J.4    Sun, H.5    Jepsen, K.J.6    Majeska, R.J.7    Yakar, S.8
  • 45
    • 80054840237 scopus 로고    scopus 로고
    • Selective osteoblast overexpression of IGF-I in mice prevents low protein-induced deterioration of bone strength and material level properties
    • Brennan-Speranza, T. C., Rizzoli, R., Kream, B. E., Rosen, C., and Ammann, P. (2011) Selective osteoblast overexpression of IGF-I in mice prevents low protein-induced deterioration of bone strength and material level properties. Bone 49, 1073-1079
    • (2011) Bone , vol.49 , pp. 1073-1079
    • Brennan-Speranza, T.C.1    Rizzoli, R.2    Kream, B.E.3    Rosen, C.4    Ammann, P.5
  • 46
    • 84871951676 scopus 로고    scopus 로고
    • Acromegaly as a cause of 1, 25-dihydroxyvitamin D-dependent hypercalcemia: Case reports and review of the literature
    • Shah, R., Licata, A., Oyesiku, N. M., and Ioachimescu, A. G. (2012) Acromegaly as a cause of 1, 25-dihydroxyvitamin D-dependent hypercalcemia: case reports and review of the literature. Pituitary 15 (Suppl 1), S17-S22
    • (2012) Pituitary , vol.15 , pp. S17-S22
    • Shah, R.1    Licata, A.2    Oyesiku, N.M.3    Ioachimescu, A.G.4
  • 48
    • 42449142714 scopus 로고    scopus 로고
    • Effects of growth hormone administration on bone mineral metabolism PTH sensitivity and PTH secretory rhythm in postmenopausal women with established osteoporosis
    • Joseph, F., Ahmad, A. M., Ul-Haq, M., Durham, B.H., Whittingham, P., Fraser, W. D., and Vora, J. P. (2008) Effects of growth hormone administration on bone mineral metabolism, PTH sensitivity and PTH secretory rhythm in postmenopausal women with established osteoporosis. J. Bone Miner. Res. 23, 721-729
    • (2008) J. Bone Miner. Res , vol.23 , pp. 721-729
    • Joseph, F.1    Ahmad, A.M.2    Ul-Haq, M.3    Durham, B.H.4    Whittingham, P.5    Fraser, W.D.6    Vora, J.P.7
  • 49
    • 0242713018 scopus 로고    scopus 로고
    • Lack of insulin-like growth factor i exaggerates the effect of calcium deficiency on bone accretion in mice
    • Kasukawa, Y., Baylink, D. J., Wergedal, J. E., Amaar, Y., Srivastava, A. K., Guo, R., and Mohan, S. (2003) Lack of insulin-like growth factor I exaggerates the effect of calcium deficiency on bone accretion in mice. Endocrinology 144, 4682-4689
    • (2003) Endocrinology , vol.144 , pp. 4682-4689
    • Kasukawa, Y.1    Baylink, D.J.2    Wergedal, J.E.3    Amaar, Y.4    Srivastava, A.K.5    Guo, R.6    Mohan, S.7
  • 50
    • 84878790490 scopus 로고    scopus 로고
    • Racial differences in cortical bone and their relationship to biochemical variables in black and white children in the early stages of puberty
    • Warden, S. J., Hill, K. M., Ferira, A. J., Laing, E. M., Martin, B. R., Hausman, D.B., Weaver, C.M., Peacock, M., and Lewis, R.D. (2013) Racial differences in cortical bone and their relationship to biochemical variables in black and white children in the early stages of puberty. Osteoporos. Int. 24, 1869-1879
    • (2013) Osteoporos. Int , vol.24 , pp. 1869-1879
    • Warden, S.J.1    Hill, K.M.2    Ferira, A.J.3    Laing, E.M.4    Martin, B.R.5    Hausman, D.B.6    Weaver, C.M.7    Peacock, M.8    Lewis, R.D.9
  • 51
    • 34848902016 scopus 로고    scopus 로고
    • Preliminary findings 25(OH) D levels and PTH are indicators of rapid bone accrual in pubertal childrens
    • Tylavsky, F.A., Ryder, K.M., Li, R., Park, V., Womack, C., Norwood, J., Carbone, L. D., and Cheng, S. (2007) Preliminary findings: 25(OH) D levels and PTH are indicators of rapid bone accrual in pubertal children. J. Am. Coll. Nutr. 26, 462-470
    • (2007) J. Am. Coll. Nutr , vol.26 , pp. 462-470
    • Tylavsky, F.A.1    Ryder, K.M.2    Li, R.3    Park, V.4    Womack, C.5    Norwood, J.6    Carbone, L.D.7    Cheng, S.8
  • 52
    • 0032894565 scopus 로고    scopus 로고
    • Skeletal unloading causes resistance of osteoprogenitor cells to parathyroid hormone and to insulin-like growth factor-I
    • Kostenuik, P. J., Harris, J., Halloran, B. P., Turner, R. T., Morey-Holton, E. R., and Bikle, D. D. (1999) Skeletal unloading causes resistance of osteoprogenitor cells to parathyroid hormone and to insulin-like growth factor-I. J. Bone Miner. Res. 14, 21-31
    • (1999) J. Bone Miner. Res , vol.14 , pp. 21-31
    • Kostenuik, P.J.1    Harris, J.2    Halloran, B.P.3    Turner, R.T.4    Morey-Holton, E.R.5    Bikle, D.D.6
  • 53
    • 0028148489 scopus 로고
    • Increased bone formation by intermittent parathyroid hormone administration is due to the stimulation of proliferation and differentiation of osteoprogenitor cells in bone marrow
    • Nishida, S., Yamaguchi, A., Tanizawa, T., Endo, N., Mashiba, T., Uchiyama, Y., Suda, T., Yoshiki, S., and Takahashi, H. E. (1994) Increased bone formation by intermittent parathyroid hormone administration is due to the stimulation of proliferation and differentiation of osteoprogenitor cells in bone marrow. Bone 15, 717-723
    • (1994) Bone , vol.15 , pp. 717-723
    • Nishida, S.1    Yamaguchi, A.2    Tanizawa, T.3    Endo, N.4    Mashiba, T.5    Uchiyama, Y.6    Suda, T.7    Yoshiki, S.8    Takahashi, H.E.9
  • 55
    • 77951473376 scopus 로고    scopus 로고
    • Synergistic effect of parathyroid hormone and growth hormone on trabecular and cortical bone formation in hypophysectomized rats
    • Guevarra, M. S., Yeh, J. K., CastroMagana, M., and Aloia, J. F. (2010) Synergistic effect of parathyroid hormone and growth hormone on trabecular and cortical bone formation in hypophysectomized rats. Horm. Res. Paediatr. 73, 248-257
    • (2010) Horm. Res. Paediatr , vol.73 , pp. 248-257
    • Guevarra, M.S.1    Yeh, J.K.2    CastroMagana, M.3    Aloia, J.F.4
  • 56
    • 0034104741 scopus 로고    scopus 로고
    • Parathyroid hormone and growth hormone have additive or synergetic effect when used as intervention treatment in ovariectomized rats with established osteopenia
    • Mosekilde, L., Tornvig, L., Thomsen, J. S., Orhii, P. B., Banu, M. J., and Kalu, D. N. (2000) Parathyroid hormone and growth hormone have additive or synergetic effect when used as intervention treatment in ovariectomized rats with established osteopenia. Bone 26, 643-651
    • (2000) Bone , vol.26 , pp. 643-651
    • Mosekilde, L.1    Tornvig, L.2    Thomsen, J.S.3    Orhii, P.B.4    Banu, M.J.5    Kalu, D.N.6
  • 57
  • 58
    • 26844521277 scopus 로고    scopus 로고
    • Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: A novel mechanism for hormonal control of osteoblastogenesis
    • Bellido, T., Ali, A. A., Gubrij, I., Plotkin, L. I., Fu, Q., OBrien, C. A., Manolagas, S. C., and Jilka, R. L. (2005) Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis. Endocrinology 146, 4577-4583
    • (2005) Endocrinology , vol.146 , pp. 4577-4583
    • Bellido, T.1    Ali, A.A.2    Gubrij, I.3    Plotkin, L.I.4    Fu, Q.5    OBrien, C.A.6    Manolagas, S.C.7    Jilka, R.L.8
  • 59
    • 21844467220 scopus 로고    scopus 로고
    • SOST is a target gene for PTH in bone
    • Keller, H., and Kneissel, M. (2005) SOST is a target gene for PTH in bone. Bone 37, 148-158
    • (2005) Bone , vol.37 , pp. 148-158
    • Keller, H.1    Kneissel, M.2
  • 61
    • 77952992328 scopus 로고    scopus 로고
    • Parathyroid hormone (PTH)-induced bone gain is blunted in SOST overexpressing and deficient mice
    • Kramer, I., Loots, G. G., Studer, A., Keller, H., and Kneissel, M. (2010) Parathyroid hormone (PTH)-induced bone gain is blunted in SOST overexpressing and deficient mice. J. Bone Miner. Res. 25, 178-189
    • (2010) J. Bone Miner. Res , vol.25 , pp. 178-189
    • Kramer, I.1    Loots, G.G.2    Studer, A.3    Keller, H.4    Kneissel, M.5
  • 63
    • 0038165507 scopus 로고    scopus 로고
    • Gene expression profiles and transcription factors involved in parathyroid hormone signaling in osteoblasts revealed by microarray and bioinformatics
    • Qin, L., Qiu, P., Wang, L., Li, X., Swarthout, J. T., Soteropoulos, P., Tolias, P., and Partridge, N. C. (2003) Gene expression profiles and transcription factors involved in parathyroid hormone signaling in osteoblasts revealed by microarray and bioinformatics. J. Biol. Chem. 278, 19723-19731
    • (2003) J. Biol. Chem , vol.278 , pp. 19723-19731
    • Qin, L.1    Qiu, P.2    Wang, L.3    Li, X.4    Swarthout, J.T.5    Soteropoulos, P.6    Tolias, P.7    Partridge, N.C.8
  • 64
    • 84857903414 scopus 로고    scopus 로고
    • Stimulation of mechano-growth factor expression by myofibrillar proteins in murine myoblasts and myotubes
    • Kravchenko, I. V., Furalyov, V. A., and Popov, V. O. (2012) Stimulation of mechano-growth factor expression by myofibrillar proteins in murine myoblasts and myotubes. Mol. Cell. Biochem. 363, 347-355
    • (2012) Mol. Cell. Biochem , vol.363 , pp. 347-355
    • Kravchenko, I.V.1    Furalyov, V.A.2    Popov, V.O.3
  • 66
    • 84896844615 scopus 로고    scopus 로고
    • Functional collaboration of insulin-like growth factor-1 receptor (IGF-1R), but not insulin receptor (IR), with acute GH signaling in mouse calvarial cells
    • Gan, Y., Paterson, A. J., Zhang, Y., Jiang, J., and Frank, S. J. (2014) Functional collaboration of insulin-like growth factor-1 receptor (IGF-1R), but not insulin receptor (IR), with acute GH signaling in mouse calvarial cells. Endocrinology 155, 1000-1009
    • (2014) Endocrinology , vol.155 , pp. 1000-1009
    • Gan, Y.1    Paterson, A.J.2    Zhang, Y.3    Jiang, J.4    Frank, S.J.5
  • 68
    • 82055194416 scopus 로고    scopus 로고
    • Signaling cross talk between growth hormone (GH) and insulin-like growth factor-I (IGF-I) in pancreatic islet b-cells
    • Ma, F., Wei, Z., Shi, C., Gan, Y., Lu, J., Frank, S. J., Balducci, J., and Huang, Y. (2011) Signaling cross talk between growth hormone (GH) and insulin-like growth factor-I (IGF-I) in pancreatic islet b-cells. Mol. Endocrinol. 25, 2119-2133
    • (2011) Mol. Endocrinol , vol.25 , pp. 2119-2133
    • Ma, F.1    Wei, Z.2    Shi, C.3    Gan, Y.4    Lu, J.5    Frank, S.J.6    Balducci, J.7    Huang, Y.8
  • 70
    • 2542420725 scopus 로고    scopus 로고
    • Physical and functional interaction of growth hormone and insulinlike growth factor-I signaling elements
    • Huang, Y., Kim, S. O., Yang, N., Jiang, J., and Frank, S. J. (2004) Physical and functional interaction of growth hormone and insulinlike growth factor-I signaling elements. Mol. Endocrinol. 18, 1471-1485
    • (2004) Mol. Endocrinol , vol.18 , pp. 1471-1485
    • Huang, Y.1    Kim, S.O.2    Yang, N.3    Jiang, J.4    Frank, S.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.