Altered GPM6A/M6 dosage impairs cognition and causes phenotypes responsive to cholesterol in human and drosophila

Human Mutation

Volumn 35, Issue 12, 2014, Pages 1495-1505

  Gregor, Anne ^a   Kramer, Jamie M ^b,e   van der Voet, Monique ^b   Schanze, Ina ^a,c   Uebe, Steffen ^a   Donders, Rogier ^d   Reis, André ^a   Schenck, Annette ^b   Zweier, Christiane ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY HOSPITAL MAGDEBURG   (Germany)

^d RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^e UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Cognition; Drosophila melanogaster; GPM6A; Learning disability

Indexed keywords

DROSOPHILA MELANOGASTER;

CHOLESTEROL; GPM6A PROTEIN, HUMAN; MEMBRANE PROTEIN; NERVE PROTEIN;

ANIMAL; COGNITIVE DEFECT; DROSOPHILA MELANOGASTER; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DOSAGE; GENE DUPLICATION; GENETICS; HUMAN; LOCOMOTION; PHENOTYPE; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SEXUAL BEHAVIOR;

ANIMALS; CHOLESTEROL; COGNITION DISORDERS; DROSOPHILA MELANOGASTER; GENE DOSAGE; GENE DUPLICATION; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LOCOMOTION; MEMBRANE GLYCOPROTEINS; NERVE TISSUE PROTEINS; PHENOTYPE; REAL-TIME POLYMERASE CHAIN REACTION; SEXUAL BEHAVIOR, ANIMAL;

EID: 84911379965     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.22697     Document Type: Article

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