GPCRs and arrestins in Airways: Implications for asthma

Handbook of Experimental Pharmacology

Volumn 219, Issue , 2014, Pages 387-403

  Penn, Raymond B ^a   Bond, Richard A ^b   Walker, Julia K L ^c  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF HOUSTON   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Airway; Arrestin asthma; Beta 2 adrenoceptor; Beta agonist; Beta blocker; Biased agonism; Desensitization; Epithelium; G protein coupled receptor; G protein coupled receptor kinase; Inflammation; Protease activated receptor; T cell; Tachyphylaxis

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM CHANNEL; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; G PROTEIN COUPLED RECEPTOR; GLUCOCORTICOID; INOSITOL 1,4,5 TRISPHOSPHATASE; INTERLEUKIN 13; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MACROPHAGE DERIVED CHEMOKINE; MUSCARINIC M3 RECEPTOR; PHOSPHOLIPASE C; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E RECEPTOR 4; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; RETINA S ANTIGEN; SALBUTAMOL; BETA ARRESTIN 2; G PROTEIN COUPLED RECEPTOR KINASE; PROTEINASE ACTIVATED RECEPTOR 2;

ACETYLCHOLINE RELEASE; ADRB2 GENE; AIRWAY RESISTANCE; ASTHMA; BRONCHOCONSTRICTION; BRONCHODILATATION; BRONCHUS MUSCLE; CALCIUM TRANSPORT; CD4+ T LYMPHOCYTE; CELL FUNCTION; DRUG EFFECT; ENZYME ACTIVITY; ENZYME SYNTHESIS; FORCED EXPIRATORY VOLUME; GENE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HEMATOPOIETIC CELL; HUMAN; LYMPHOCYTE MIGRATION; LYMPHOCYTE PROLIFERATION; MUSCLE CONTRACTION; MUSCLE TONE; NONHUMAN; PATHOGENESIS; PNEUMONIA; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT ALLERGY; REVIEW; SIGNAL TRANSDUCTION; TH1 CELL; TH2 CELL; TREATMENT RESPONSE; AIRWAY SMOOTH MUSCLE CELL; ALLERGIC PNEUMONITIS; ARTICLE; BREATHING MUSCLE; CELLS BY BODY ANATOMY; SMOOTH MUSCLE CONTRACTION;

AIRWAY RESISTANCE; ANIMALS; ANTI-ASTHMATIC AGENTS; ARRESTINS; ASTHMA; HUMANS; INFLAMMATION; MOLECULAR TARGETED THERAPY; MUSCLE CONTRACTION; MUSCLE, SMOOTH; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84958538636     PISSN: 01712004     EISSN: 18650325     Source Type: Book Series    
DOI: 10.1007/978-3-642-41199-1_20     Document Type: Review

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