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Volumn 16, Issue 1, 2016, Pages

Rg3-enriched ginseng extract ameliorates scopolamine-induced learning deficits in mice

Author keywords

Acetylcholinesterase; Ginseng; Memory; NF B; Rg3; Scopolamine

Indexed keywords

ACETYLCHOLINESTERASE; GINSENG EXTRACT; GINSENOSIDE RG 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SCOPOLAMINE; SYNAPTOTAGMIN I; GINSENOSIDE; PLANT EXTRACT; SCOPOLAMINE BROMIDE;

EID: 84958242069     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/s12906-016-1050-z     Document Type: Article
Times cited : (31)

References (39)
  • 1
    • 0344549853 scopus 로고    scopus 로고
    • Ginseng pharmacology: multiple constituents and multiple actions
    • Attele AS, Wu JA, Yuan CS. Ginseng pharmacology: multiple constituents and multiple actions. Biochem Pharmacol. 1999;58(11):1685-93.
    • (1999) Biochem Pharmacol , vol.58 , Issue.11 , pp. 1685-1693
    • Attele, A.S.1    Wu, J.A.2    Yuan, C.S.3
  • 3
    • 0026504109 scopus 로고
    • Recent advances on ginseng research in China
    • Liu CX, Xiao PG. Recent advances on ginseng research in China. J Ethnopharmacol. 1992;36(1):27-38.
    • (1992) J Ethnopharmacol , vol.36 , Issue.1 , pp. 27-38
    • Liu, C.X.1    Xiao, P.G.2
  • 4
    • 11844298464 scopus 로고    scopus 로고
    • Neuroprotective effect of 20(S)-ginsenoside Rg3 on cerebral ischemia in rats
    • Tian J, Fu F, Geng M, Jiang Y, Yang J, Jiang W, et al. Neuroprotective effect of 20(S)-ginsenoside Rg3 on cerebral ischemia in rats. Neurosci Lett. 2005;374(2):92-7.
    • (2005) Neurosci Lett , vol.374 , Issue.2 , pp. 92-97
    • Tian, J.1    Fu, F.2    Geng, M.3    Jiang, Y.4    Yang, J.5    Jiang, W.6
  • 5
    • 64549158006 scopus 로고    scopus 로고
    • Ginsenoside Rg3 promotes beta-amyloid peptide degradation by enhancing gene expression of neprilysin
    • Yang L, Hao J, Zhang J, Xia W, Dong X, Hu X, et al. Ginsenoside Rg3 promotes beta-amyloid peptide degradation by enhancing gene expression of neprilysin. J Pharm Pharmacol. 2009;61(3):375-80.
    • (2009) J Pharm Pharmacol , vol.61 , Issue.3 , pp. 375-380
    • Yang, L.1    Hao, J.2    Zhang, J.3    Xia, W.4    Dong, X.5    Hu, X.6
  • 6
    • 0031596324 scopus 로고    scopus 로고
    • Ginsenosides Rb1 and Rg3 protect cultured rat cortical cells from glutamate-induced neurodegeneration
    • Kim YC, Kim SR, Markelonis GJ, Oh TH. Ginsenosides Rb1 and Rg3 protect cultured rat cortical cells from glutamate-induced neurodegeneration. J Neurosci Res. 1998;53(4):426-32.
    • (1998) J Neurosci Res , vol.53 , Issue.4 , pp. 426-432
    • Kim, Y.C.1    Kim, S.R.2    Markelonis, G.J.3    Oh, T.H.4
  • 8
    • 44249127445 scopus 로고    scopus 로고
    • Cognitive-enhancing and antioxidant activities of iridoid glycosides from Scrophularia buergeriana in scopolamine-treated mice
    • Jeong EJ, Lee KY, Kim SH, Sung SH, Kim YC. Cognitive-enhancing and antioxidant activities of iridoid glycosides from Scrophularia buergeriana in scopolamine-treated mice. Eur J Pharmacol. 2008;588(1):78-84.
    • (2008) Eur J Pharmacol , vol.588 , Issue.1 , pp. 78-84
    • Jeong, E.J.1    Lee, K.Y.2    Kim, S.H.3    Sung, S.H.4    Kim, Y.C.5
  • 9
    • 0026388912 scopus 로고
    • Effects of NMDA modulation in scopolamine dementia
    • Jones RW, Wesnes KA, Kirby J. Effects of NMDA modulation in scopolamine dementia. Ann N Y Acad Sci. 1991;640:241-4.
    • (1991) Ann N Y Acad Sci , vol.640 , pp. 241-244
    • Jones, R.W.1    Wesnes, K.A.2    Kirby, J.3
  • 10
    • 0025939057 scopus 로고
    • Reversal effect of DM-9384 on scopolamine-induced acetylcholine depletion in certain regions of the mouse brain
    • Abe E. Reversal effect of DM-9384 on scopolamine-induced acetylcholine depletion in certain regions of the mouse brain. Psychopharmacology. 1991;105(3):310-6.
    • (1991) Psychopharmacology , vol.105 , Issue.3 , pp. 310-316
    • Abe, E.1
  • 11
    • 84902532816 scopus 로고    scopus 로고
    • Sulforaphane alleviates scopolamine-induced memory impairment in mice
    • Lee S, Kim J, Seo SG, Choi BR, Han JS, Lee KW, et al. Sulforaphane alleviates scopolamine-induced memory impairment in mice. Pharmacol Res. 2014;85:23-32.
    • (2014) Pharmacol Res , vol.85 , pp. 23-32
    • Lee, S.1    Kim, J.2    Seo, S.G.3    Choi, B.R.4    Han, J.S.5    Lee, K.W.6
  • 12
    • 0019972810 scopus 로고
    • The cholinergic hypothesis of geriatric memory dysfunction
    • Bartus RT, Dean 3rd RL, Beer B, Lippa AS. The cholinergic hypothesis of geriatric memory dysfunction. Science. 1982;217(4558):408-14.
    • (1982) Science , vol.217 , Issue.4558 , pp. 408-414
    • Bartus, R.T.1    Dean, R.L.2    Beer, B.3    Lippa, A.S.4
  • 13
    • 0742307290 scopus 로고    scopus 로고
    • Generation of ginsenosides Rg3 and Rh2 from North American ginseng
    • Popovich DG, Kitts DD. Generation of ginsenosides Rg3 and Rh2 from North American ginseng. Phytochemistry. 2004;65(3):337-44.
    • (2004) Phytochemistry , vol.65 , Issue.3 , pp. 337-344
    • Popovich, D.G.1    Kitts, D.D.2
  • 14
    • 69049084468 scopus 로고    scopus 로고
    • Effects of steaming the root of Panax notoginseng on chemical composition and anticancer activities
    • Sun S, Wang CZ, Tong R, Li XL, Fishbein A, Wang Q, et al. Effects of steaming the root of Panax notoginseng on chemical composition and anticancer activities. Food Chem. 2010;118(2):307-14.
    • (2010) Food Chem , vol.118 , Issue.2 , pp. 307-314
    • Sun, S.1    Wang, C.Z.2    Tong, R.3    Li, X.L.4    Fishbein, A.5    Wang, Q.6
  • 15
    • 84871263031 scopus 로고    scopus 로고
    • Stimulation of Rg3 ginsenoside biosynthesis in ginseng hairy roots elicited by methyl jasmonate
    • Kim OT, Yoo NH, Kim GS, Kim YC, Bang KH, Hyun DY, et al. Stimulation of Rg3 ginsenoside biosynthesis in ginseng hairy roots elicited by methyl jasmonate. Plant Cell Tiss Org. 2013;112(1):87-93.
    • (2013) Plant Cell Tiss Org , vol.112 , Issue.1 , pp. 87-93
    • Kim, O.T.1    Yoo, N.H.2    Kim, G.S.3    Kim, Y.C.4    Bang, K.H.5    Hyun, D.Y.6
  • 18
    • 84935919935 scopus 로고    scopus 로고
    • Nootropic, neuroprotective and neurotrophic effects of phloretin in scopolamine induced amnesia in mice
    • Ghumatkar PJ, Patil SP, Jain PD, Tambe RM, Sathaye S. Nootropic, neuroprotective and neurotrophic effects of phloretin in scopolamine induced amnesia in mice. Pharmacol Biochem Behav. 2015;135:182-91.
    • (2015) Pharmacol Biochem Behav , vol.135 , pp. 182-191
    • Ghumatkar, P.J.1    Patil, S.P.2    Jain, P.D.3    Tambe, R.M.4    Sathaye, S.5
  • 19
    • 84911880328 scopus 로고    scopus 로고
    • Ameliorative effect of rosmarinic acid on scopolamine-induced memory impairment in rats
    • Hasanein P, Mahtaj AK. Ameliorative effect of rosmarinic acid on scopolamine-induced memory impairment in rats. Neurosci Lett. 2015;585:23-7.
    • (2015) Neurosci Lett , vol.585 , pp. 23-27
    • Hasanein, P.1    Mahtaj, A.K.2
  • 20
    • 84919347988 scopus 로고    scopus 로고
    • Procognitive effect of AC-3933 in aged mice, and synergistic effect of combination with donepezil in scopolamine-treated mice
    • Hashimoto T, Hatayama Y, Nakamichi K, Yoshida N. Procognitive effect of AC-3933 in aged mice, and synergistic effect of combination with donepezil in scopolamine-treated mice. Eur J Pharmacol. 2014;745:123-8.
    • (2014) Eur J Pharmacol , vol.745 , pp. 123-128
    • Hashimoto, T.1    Hatayama, Y.2    Nakamichi, K.3    Yoshida, N.4
  • 21
    • 84930871495 scopus 로고    scopus 로고
    • Effects of the hydro-alcoholic extract of Nigella sativa on scopolamine-induced spatial memory impairment in rats and its possible mechanism
    • Hosseini M, Mohammadpour T, Karami R, Rajaei Z, Reza Sadeghnia H, Soukhtanloo M. Effects of the hydro-alcoholic extract of Nigella sativa on scopolamine-induced spatial memory impairment in rats and its possible mechanism. Chin J Integr Med. 2015;21(6):438-44.
    • (2015) Chin J Integr Med , vol.21 , Issue.6 , pp. 438-444
    • Hosseini, M.1    Mohammadpour, T.2    Karami, R.3    Rajaei, Z.4    Reza Sadeghnia, H.5    Soukhtanloo, M.6
  • 22
    • 84888433045 scopus 로고    scopus 로고
    • Glucosamine alleviates scopolamine induced spatial learning and memory deficits in rats
    • Jamialahmadi K, Sadeghnia HR, Mohammadi G, Kazemabad AM, Hosseini M. Glucosamine alleviates scopolamine induced spatial learning and memory deficits in rats. Pathophysiol. 2013;20(4):263-7.
    • (2013) Pathophysiol , vol.20 , Issue.4 , pp. 263-267
    • Jamialahmadi, K.1    Sadeghnia, H.R.2    Mohammadi, G.3    Kazemabad, A.M.4    Hosseini, M.5
  • 23
    • 84875248399 scopus 로고    scopus 로고
    • Decaffeinated coffee prevents scopolamine-induced memory impairment in rats
    • Jang YJ, Kim J, Shim J, Kim CY, Jang JH, Lee KW, et al. Decaffeinated coffee prevents scopolamine-induced memory impairment in rats. Behav Brain Res. 2013;245:113-9.
    • (2013) Behav Brain Res , vol.245 , pp. 113-119
    • Jang, Y.J.1    Kim, J.2    Shim, J.3    Kim, C.Y.4    Jang, J.H.5    Lee, K.W.6
  • 24
    • 77949603218 scopus 로고    scopus 로고
    • Effect of wild ginseng on scopolamine-induced acetylcholine depletion in the rat hippocampus
    • Lee B, Park J, Kwon S, Park MW, Oh SM, Yeom MJ, et al. Effect of wild ginseng on scopolamine-induced acetylcholine depletion in the rat hippocampus. J Pharm Pharmacol. 2010;62(2):263-71.
    • (2010) J Pharm Pharmacol , vol.62 , Issue.2 , pp. 263-271
    • Lee, B.1    Park, J.2    Kwon, S.3    Park, M.W.4    Oh, S.M.5    Yeom, M.J.6
  • 25
    • 84946949622 scopus 로고    scopus 로고
    • Japanese Huperzia serrata extract and the constituent, huperzine A, ameliorate the scopolamine-induced cognitive impairment in mice
    • Ohba T, Yoshino Y, Ishisaka M, Abe N, Tsuruma K, Shimazawa M, et al. Japanese Huperzia serrata extract and the constituent, huperzine A, ameliorate the scopolamine-induced cognitive impairment in mice. Biosci Biotechnol Biochem. 2015;79:1838.
    • (2015) Biosci Biotechnol Biochem , vol.79 , pp. 1838
    • Ohba, T.1    Yoshino, Y.2    Ishisaka, M.3    Abe, N.4    Tsuruma, K.5    Shimazawa, M.6
  • 26
    • 84928800320 scopus 로고    scopus 로고
    • Honokiol improves learning and memory impairments induced by scopolamine in mice
    • Xian YF, Ip SP, Mao QQ, Su ZR, Chen JN, Lai XP, et al. Honokiol improves learning and memory impairments induced by scopolamine in mice. Eur J Pharmacol. 2015;760:88-95.
    • (2015) Eur J Pharmacol , vol.760 , pp. 88-95
    • Xian, Y.F.1    Ip, S.P.2    Mao, Q.Q.3    Su, Z.R.4    Chen, J.N.5    Lai, X.P.6
  • 27
    • 0027214025 scopus 로고
    • Severity of spatial learning impairment in aging: development of a learning index for performance in the Morris water maze
    • Gallagher M, Burwell R, Burchinal M. Severity of spatial learning impairment in aging: development of a learning index for performance in the Morris water maze. Behav Neurosci. 1993;107(4):618-26.
    • (1993) Behav Neurosci , vol.107 , Issue.4 , pp. 618-626
    • Gallagher, M.1    Burwell, R.2    Burchinal, M.3
  • 28
    • 33845672995 scopus 로고    scopus 로고
    • Reductions in levels of the Alzheimer's amyloid beta peptide after oral administration of ginsenosides
    • Chen F, Eckman EA, Eckman CB. Reductions in levels of the Alzheimer's amyloid beta peptide after oral administration of ginsenosides. FASEB J. 2006;20(8):1269-71.
    • (2006) FASEB J , vol.20 , Issue.8 , pp. 1269-1271
    • Chen, F.1    Eckman, E.A.2    Eckman, C.B.3
  • 29
    • 0037683293 scopus 로고    scopus 로고
    • Ginsenoside Rg1 increases ischemia-induced cell proliferation and survival in the dentate gyrus of adult gerbils
    • Shen L, Zhang J. Ginsenoside Rg1 increases ischemia-induced cell proliferation and survival in the dentate gyrus of adult gerbils. Neurosci Lett. 2003;344(1):1-4.
    • (2003) Neurosci Lett , vol.344 , Issue.1 , pp. 1-4
    • Shen, L.1    Zhang, J.2
  • 30
    • 0030831972 scopus 로고    scopus 로고
    • How does the brain organize memories?
    • Eichenbaum H. How does the brain organize memories? Science. 1997;277(5324):330-2.
    • (1997) Science , vol.277 , Issue.5324 , pp. 330-332
    • Eichenbaum, H.1
  • 31
    • 4043074138 scopus 로고    scopus 로고
    • Cholinesterase inhibitors: new roles and therapeutic alternatives
    • Giacobini E. Cholinesterase inhibitors: new roles and therapeutic alternatives. Pharmacol Res. 2004;50(4):433-40.
    • (2004) Pharmacol Res , vol.50 , Issue.4 , pp. 433-440
    • Giacobini, E.1
  • 33
    • 67649411532 scopus 로고    scopus 로고
    • Timosaponin AIII, a saponin isolated from Anemarrhena asphodeloides, ameliorates learning and memory deficits in mice
    • Lee B, Jung K, Kim DH. Timosaponin AIII, a saponin isolated from Anemarrhena asphodeloides, ameliorates learning and memory deficits in mice. Pharmacol Biochem Behav. 2009;93(2):121-7.
    • (2009) Pharmacol Biochem Behav , vol.93 , Issue.2 , pp. 121-127
    • Lee, B.1    Jung, K.2    Kim, D.H.3
  • 34
    • 0037130374 scopus 로고    scopus 로고
    • Modulatory role of cyclooxygenase inhibitors in aging- and scopolamine or lipopolysaccharide-induced cognitive dysfunction in mice
    • Jain NK, Patil CS, Kulkarni SK, Singh A. Modulatory role of cyclooxygenase inhibitors in aging- and scopolamine or lipopolysaccharide-induced cognitive dysfunction in mice. Behav Brain Res. 2002;133(2):369-76.
    • (2002) Behav Brain Res , vol.133 , Issue.2 , pp. 369-376
    • Jain, N.K.1    Patil, C.S.2    Kulkarni, S.K.3    Singh, A.4
  • 35
    • 60749131389 scopus 로고    scopus 로고
    • Mangiferin ameliorates scopolamine-induced learning deficits in mice
    • Jung K, Lee B, Han SJ, Ryu JH, Kim DH. Mangiferin ameliorates scopolamine-induced learning deficits in mice. Biol Pharm Bull. 2009;32(2):242-6.
    • (2009) Biol Pharm Bull , vol.32 , Issue.2 , pp. 242-246
    • Jung, K.1    Lee, B.2    Han, S.J.3    Ryu, J.H.4    Kim, D.H.5
  • 36
    • 84892550627 scopus 로고    scopus 로고
    • Total isoflavones from soybean and tempeh reversed scopolamine-induced amnesia, improved cholinergic activities and reduced neuroinflammation in brain
    • Ahmad A, Ramasamy K, Jaafar SM, Majeed AB, Mani V. Total isoflavones from soybean and tempeh reversed scopolamine-induced amnesia, improved cholinergic activities and reduced neuroinflammation in brain. Food Chem Toxicol. 2014;65:120-8.
    • (2014) Food Chem Toxicol , vol.65 , pp. 120-128
    • Ahmad, A.1    Ramasamy, K.2    Jaafar, S.M.3    Majeed, A.B.4    Mani, V.5
  • 37
    • 84861035259 scopus 로고    scopus 로고
    • Phellodendron amurense and Its Major Alkaloid Compound, Berberine Ameliorates Scopolamine-Induced Neuronal Impairment and Memory Dysfunction in Rats
    • Lee B, Sur B, Shim I, Lee H, Hahm DH. Phellodendron amurense and Its Major Alkaloid Compound, Berberine Ameliorates Scopolamine-Induced Neuronal Impairment and Memory Dysfunction in Rats. Korean J Physiol Pharmacol. 2012;16(2):79-89.
    • (2012) Korean J Physiol Pharmacol , vol.16 , Issue.2 , pp. 79-89
    • Lee, B.1    Sur, B.2    Shim, I.3    Lee, H.4    Hahm, D.H.5
  • 38
    • 84925349748 scopus 로고    scopus 로고
    • Evaluation of Cucurbita maxima extract against scopolamine-induced amnesia in rats: implication of tumour necrosis factor alpha
    • Jawaid T, Shakya AK, Siddiqui HH, Kamal M. Evaluation of Cucurbita maxima extract against scopolamine-induced amnesia in rats: implication of tumour necrosis factor alpha. Z Naturforsch C. 2014;69(9-10):407-17.
    • (2014) Z Naturforsch C , vol.69 , Issue.9-10 , pp. 407-417
    • Jawaid, T.1    Shakya, A.K.2    Siddiqui, H.H.3    Kamal, M.4
  • 39
    • 0031438499 scopus 로고    scopus 로고
    • The role of interleukin 1 in acute neurodegeneration and stroke: pathophysiological and therapeutic implications
    • Rothwell N, Allan S, Toulmond S. The role of interleukin 1 in acute neurodegeneration and stroke: pathophysiological and therapeutic implications. J Clin Invest. 1997;100(11):2648-52.
    • (1997) J Clin Invest , vol.100 , Issue.11 , pp. 2648-2652
    • Rothwell, N.1    Allan, S.2    Toulmond, S.3


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