Glucosamine alleviates scopolamine induced spatial learning and memory deficits in rats

Pathophysiology

Volumn 20, Issue 4, 2013, Pages 263-267

  Jamialahmadi, Khadijeh ^a   Sadeghnia, Hamid Reza ^a   Mohammadi, Ghazaleh ^b   Kazemabad, Ali Masoudi ^c   Hosseini, Mahmoud ^a  

^a MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b PAYAME NOOR UNIVERSITY   (Iran)

^c ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

D Glucosamine; Male rats; Morris water maze; Scopolamine; Spatial learning and memory

Indexed keywords

GLUCOSAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ESCAPE BEHAVIOR; LATENT PERIOD; LEARNING DISORDER; MALE; MAZE TEST; MEMORY DISORDER; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SPATIAL LEARNING; SPATIAL MEMORY;

EID: 84888433045     PISSN: 09284680     EISSN: 1873149X     Source Type: Journal    
DOI: 10.1016/j.pathophys.2013.04.003     Document Type: Article

References (42)

1. Schipper H.M. Brain iron deposition and the free radical-mitochondrial theory of ageing. Ageing Research Reviews 2004, 3(3):265-301.
2. Giacobini E. Long-term stabilizing effect of cholinesterase inhibitors in the therapy of Alzheimer' disease. Journal of Neural Transmission 2002, (Suppl. 62):181-187.
3. Wang J.Z., Wang Z.F. Role of melatonin in Alzheimer-like neurodegeneration. Acta Pharmacologica Sinica 2006, 27:41-49.
4. Giovannini M.G., Casamenti F., Bartolini L., Pepeu G. The brain cholinergic system as a target of cognition enhancers. Behavioural Brain Research 1997, 83:1-5.
5. Mattson M.P., Pedersen W.A. Effects of amyloid precursor protein derivatives and oxidative stress on basal forebrain cholinergic systems in Alzheimer's disease. International Journal of Developmental Neuroscience 1998, 16:737-753.
6. Salvatore S., Heuschkel R., Tomlin S., Davies S.E., Edwards S., Walker-Smith J.A., French I., Murch S.H. A pilot study of N-acetyl glucosamine, a nutritional substrate for glycosaminoglycan synthesis, in paediatric chronic inflammatory bowel disease. Alimentary Pharmacology & Therapeutics 2000, 14:1567-1579.
7. Talent J.M., Gracy R.W. Pilot study of oral polymeric N-acetyl-d-glucosamine as a potential treatment for patients with osteoarthritis. Clinical Therapeutics 1996, 18:1184-1190.
8. Gindzienski A., Zwierz K. The activity of N-acetylglucosamine kinase from human gastric mucosa. Biochemical Medicine 1971, 5:188-194.
9. Xing R., Liu S., Guo Z., Yu H., Li C., Ji X., Feng J., Li P. The antioxidant activity of glucosamine hydrochloride in vitro. Bioorganic and Medicinal Chemistry 2006, 15:1706-1709.
10. Yan Y., Wanshun L., Baoqin H., Changhong W., Chenwei F., Bing L., Liehuan C. The antioxidative and immunostimulating properties of d-glucosamine. International Immunopharmacology 2007, 7:29-35.
11. Hwang S.Y., Shin J.H., Hwang J.S., Kim S.Y., Shin J.A., Oh E.S., Oh S., Kim J.B., Lee J.K., Han I.O. Glucosamine exerts a neuroprotective effect via suppression of inflammation in rat brain ischemia/reperfusion injury. Glia 2010, 58:1881-1892.
12. Forchhammer L., Thorn M., Met O., Gad M., Weidner M.S., Claesson M.H. Immunobiological effects of glucosamine in vitro. Scandinavian Journal of Immunology 2003, 58:404-411.
13. Gallagher M., Burwell R., Burchinal M. Severity of spatial learning impairment in aging: development of a learning index for performance in the Morris water maze. Behavioral Neuroscience 1993, 107:618-626.
14. Morris R. Developments of a water-maze procedure for studying spatial learning in the rat. Journal of Neuroscience Methods 1984, 11(May (1)):47-60.
15. Hosseini M., Dastghaib S.S., Rafatpanah H., Hadjzadeh M.A., Nahrevanian H., Farrokhi I. Nitric oxide contributes to learning and memory deficits observed in hypothyroid rats during neonatal and juvenile growth. Clinics [Sao Paulo] 2010, 65:1175-1181.
16. Hosseini M., Hadjzadeh M.A., Derakhshan M., Havakhah S., Rassouli F.B., Rakhshandeh H., Saffarzadeh F. The beneficial effects of olibanum on memory deficit induced by hypothyroidism in adult rats tested in Morris water maze. Archives of Pharmacal Research 2010, 33:463-468.
17. Hosseini M., Headari R., Oryan S., Hadjzadeh M.A., Saffarzadeh F., Khazaei M. The effect of chronic administration of l-arginine on the learning and memory of estradiol-treated ovariectomized rats tested in the morris water maze. Clinics [Sao Paulo] 2010, 65:803-807.
18. Hosseini M., Nemati Karimooy H.A., Hadjzadeh M.A., Safari V. Inducible nitric oxide synthase inhibitor aminoguanidine, differently affects Morris water maze tasks of ovariectomized and naive female rats. Acta Physiologica Hungarica 2011, 98:421-432.
19. Shintani T., Yamazaki F., Katoh T., Umekawa M., Matahira Y., Hori S., Kakizuka A., Totani K., Yamamoto K., Ashida H. Glucosamine induces autophagy via an mTOR-independent pathway. Biochemical and Biophysical Research Communications 2010, 391:1775-1779.
20. Hua J., Suguro S., Hirano S., Sakamoto K., Nagaoka I. Preventive actions of a high dose of glucosamine on adjuvant arthritis in rats. Inflammation Research 2005, 54:127-132.
21. Valvason C., Musacchio E., Pozzuoli A., Ramonda R., Aldegheri R., Punzi L. Influence of glucosamine sulphate on oxidative stress in human osteoarthritic chondrocytes: effects on HO-1, p22[Phox] and iNOS expression. Rheumatology [Oxford] 2008, 47:31-35.
22. Zou L., Yang S., Champattanachai V., Hu S., Chaudry I.H., Marchase R.B., Chatham J.C. Glucosamine improves cardiac function following trauma-hemorrhage by increased protein O-GlcNAcylation and attenuation of NF-{kappa}B signaling. American Journal of Physiology: Heart and Circulatory Physiology 2009, 296:H515-H523.
23. Chan P.S., Caron J.P., Rosa G.J.M., Orth M.W. Glucosamine and chondroitin sulfate regulate gene expression and synthesis of nitric oxide and prostaglandin E2 in articular cartilage explants. Osteoarthritis Cartilage 2005, 13:387-394.
24. Chan P.S., Caron J.P., Orth M.W. Short-term gene expression changes in cartilage explants stimulated with interleukin beta plus glucosamine and chondroitin sulfate. Journal of Rheumatology 2006, 33:1329-1340.
25. Kim J.A., Ahn B.N., Kong C.S., Kim S.K. Anti-inflammatory action of sulfated glucosamine on cytokine regulation in LPS-activated PMA-differentiated THP-1 macrophages. Inflammation Research 2011, 60:1131-1138.
26. Jin M., Suh S.J., Yang J.H., Lu Y., Kim S.J., Kwon S., Jo T.H., Kim J.W., Park Y.I., Ahn G.W., Lee C.K., Kim C.H., Son J.K., Son K.H., Chang H.W. Anti-inflammatory activity of bark of Dioscorea batatas DECNE through the inhibition of iNOS and COX-2 expressions in RAW264. 7 cells via NF-[kappa] B and ERK1/2 inactivation. Food and Chemical Toxicology 2010, 48:3073-3079.
27. Yi H.A., Yi S.D., Jang B.C., Song D.K., Shin D.H., Mun K.C., Kim S.P., Suh S.I., Bae J.H. Inhibitory effects of glucosamine on lipopolysaccharide-induced activation in microglial cells. Clinical and Experimental Pharmacology and Physiology 2005, 32:1097-1103.
28. Giri R.K., Selvaraj S.K., Kalra V.K. Amyloid peptide-induced cytokine and chemokine expression in THP-1 monocytes is blocked by small inhibitory RNA duplexes for early growth response-1 messenger RNA. Journal of Immunology 2003, 170:5281-5294.
29. Gasparini L., Ongini E., Wenk G. Non-steroidal anti-inflammatory drugs (NSAIDs) in Alzheimer's disease: old and new mechanisms of action. Journal of Neurochemistry 2004, 91:521-536.
30. Wyss-Coray T. Inflammation in Alzheimer disease: driving force, bystander or beneficial response?. Nature Medicine 2006, 12:1005-1015.
31. Wyss-Coray T., Rogers J. Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature. Cold Spring Harbor Perspectives in Medicine 2012, 2:a006346.
32. Azizi-Malekabadi H., Hosseini M., Soukhtanloo M., Sadeghian R., Fereidoni M., Khodabandehloo F. Different effects of scopolamine on learning, memory, and nitric oxide metabolite levels in hippocampal tissues of ovariectomized and Sham-operated rats. Arquivos de Neuro-Psiquiatria 2012, 70:447-452.
33. Khalifa A.E. Pro-oxidant activity of zuclopenthixol in vivo: differential effect of the drug on brain oxidative status of scopolamine-treated rats. Human and Experimental Toxicology 2004, 23:439-445.
34. Fan Y., Hu J., Li J., Yang Z., Xin X., Wang J., Ding J., Geng M. Effect of acidic oligosaccharide sugar chain on scopolamine-induced memory impairment in rats and its related mechanisms. Neuroscience Letters 2005, 374:222-226.
35. Bickford P.C., Gould T., Briederick L., Chadman K., Pollock A., Young D., Shukitt-Hale B., Joseph J. Antioxidant-rich diets improve cerebellar physiology and motor learning in aged rats. Brain Research 2000, 866:211-217.
36. Jeong E.J., Lee K.Y., Kim S.H., Sung S.H., Kim Y.C. Cognitive-enhancing and antioxidant activities of iridoid glycosides from Scrophularia buergeriana in scopolamine-treated mice. European Journal of Pharmacology 2008, 588:78-84.
37. Yoshiyama Y., Kojima A., Ishikawa C., Arai K. Anti-inflammatory action of donepezil ameliorates tau pathology, synaptic loss, and neurodegeneration in a tauopathy mouse model. Journal of Alzheimer's Disease 2010, 22:295-306.
38. Yoshiyama Y., Kojima A., Itoh K., Uchiyama T., Arai K. Anticholinergics boost the pathological process of neurodegeneration with increased inflammation in a tauopathy mouse model. Neurobiology of Disease 2012, 45:329-336.
39. Pavlov V.A., Parrish W.R., Rosas-Ballina M., Ochani M., Puerta M., Ochani K., Puerta M., Ochani K. Brain acetylcholinesterase activity controls systemic cytokine levels through the cholinergic anti-inflammatory pathway. Brain, Behavior, and Immunity 2009, 23:41-45.
40. Pavlov V.A., Tracey K.J. The cholinergic anti-inflammatory pathway. Brain, Behavior, and Immunity 2005, 19:493-499.
41. Lee K.Y., Shibutani M., Takagi H., Arimura T., Takigami S., Uneyama C., Kato N., Hirose M. Subchronic toxicity study of dietary N-acetylglucosamine in F344 rats. Food and Chemical Toxicology 2004, 42:687-695.
42. Molnar Z., Bekesi J.G. Cytotoxic effects of d-glucosamine on the ultrastructures of normal and neoplastic tissues in vivo. Cancer Research 1972, 32:756-765.