메뉴 건너뛰기




Volumn 24, Issue 24, 2004, Pages 5459-5466

Choline transporter 1 maintains cholinergic function in choline acetyltransferase haploinsufficiency

Author keywords

Acetylcholine; Behavior; Choline acetyltransferase; Choline transporter; Cholinergic; Congenital myasthenic syndrome with episodic apnea

Indexed keywords

ACETYLCHOLINE; CARRIER PROTEIN; CHOLINE ACETYLTRANSFERASE; CHOLINE TRANSPORTER 1; MESSENGER RNA; NEUROTRANSMITTER; UNCLASSIFIED DRUG;

EID: 3042602081     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1106-04.2004     Document Type: Article
Times cited : (87)

References (48)
  • 3
    • 0019455852 scopus 로고
    • Choline biosynthesis by a preparation enriched in synaptosomes from rat brain
    • Blusztajn JK, Wurtman RJ (1981) Choline biosynthesis by a preparation enriched in synaptosomes from rat brain. Nature 290:417-418.
    • (1981) Nature , vol.290 , pp. 417-418
    • Blusztajn, J.K.1    Wurtman, R.J.2
  • 4
    • 0020559906 scopus 로고
    • Choline and cholinergic neurons
    • Blusztajn JK, Wurtman RJ (1983) Choline and cholinergic neurons. Science 221:614-620.
    • (1983) Science , vol.221 , pp. 614-620
    • Blusztajn, J.K.1    Wurtman, R.J.2
  • 5
    • 0023252072 scopus 로고
    • Synthesis of acetylcholine from choline derived from phosphatidylcholine in a human neuronal cell line
    • Blusztajn JK, Liscovitch M, Richardson UI (1987) Synthesis of acetylcholine from choline derived from phosphatidylcholine in a human neuronal cell line. Proc Natl Acad Sci USA 84:5474-5477.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 5474-5477
    • Blusztajn, J.K.1    Liscovitch, M.2    Richardson, U.I.3
  • 7
    • 0022637220 scopus 로고
    • 4-(1-Naphthylvinyl)pyridine decreases brain acetylcholine in vivo, but does not alter the level of acetylCoA
    • Budai D, Ricny J, Kasa P, Tucek S (1986) 4-(1-Naphthylvinyl)pyridine decreases brain acetylcholine in vivo, but does not alter the level of acetylCoA. J Neurochem 46:990-992.
    • (1986) J Neurochem , vol.46 , pp. 990-992
    • Budai, D.1    Ricny, J.2    Kasa, P.3    Tucek, S.4
  • 9
    • 0023277545 scopus 로고
    • Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N (1987) Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 10
    • 0017352651 scopus 로고
    • The effect of preganglionic nerve stimulation on the accumulation of certain analogues of choline by a sympathetic ganglion
    • Collier B, Ilson D (1977) The effect of preganglionic nerve stimulation on the accumulation of certain analogues of choline by a sympathetic ganglion. J Physiol (Lond) 264:489-509.
    • (1977) J Physiol (Lond) , vol.264 , pp. 489-509
    • Collier, B.1    Ilson, D.2
  • 11
    • 0034234806 scopus 로고    scopus 로고
    • Expression, purification and characterization of recombinant human choline acetyltransferase: Phosphorylation of the enzyme regulates catalytic activity
    • Dobransky T, Davis WL, Xiao GH, Rylett RJ (2000) Expression, purification and characterization of recombinant human choline acetyltransferase: phosphorylation of the enzyme regulates catalytic activity. Biochem J 349:141-151.
    • (2000) Biochem J , vol.349 , pp. 141-151
    • Dobransky, T.1    Davis, W.L.2    Xiao, G.H.3    Rylett, R.J.4
  • 12
    • 0035933779 scopus 로고    scopus 로고
    • Functional characterization of phosphorylation of 69-kDa human choline acetyltransferase at serine 440 by protein kinase C
    • Dobransky T, Davis WL, Rylett RJ (2001) Functional characterization of phosphorylation of 69-kDa human choline acetyltransferase at serine 440 by protein kinase C. J Biol Chem 276:22244-22250.
    • (2001) J Biol Chem , vol.276 , pp. 22244-22250
    • Dobransky, T.1    Davis, W.L.2    Rylett, R.J.3
  • 13
    • 0020045188 scopus 로고
    • Effects of choline and glucose on atropine-induced alterations of acetylcholine synthesis and content in the caudate nuclei of rats
    • Dolezal V, Tucek S (1982) Effects of choline and glucose on atropine-induced alterations of acetylcholine synthesis and content in the caudate nuclei of rats. Brain Res 240:285-293.
    • (1982) Brain Res , vol.240 , pp. 285-293
    • Dolezal, V.1    Tucek, S.2
  • 14
    • 0015806980 scopus 로고
    • Comparative studies on synaptosomes: Uptake of (N-Me-3H)choline by synaptosomes from squid optic lobes
    • Dowdall MJ, Simon EJ (1973) Comparative studies on synaptosomes: uptake of (N-Me-3H)choline by synaptosomes from squid optic lobes. J Neurochem 21:969-982.
    • (1973) J Neurochem , vol.21 , pp. 969-982
    • Dowdall, M.J.1    Simon, E.J.2
  • 16
    • 0016468979 scopus 로고
    • A rapid radiochemical method for the determination of choline acetyltransferase
    • Fonnum F (1975) A rapid radiochemical method for the determination of choline acetyltransferase. J Neurochem 24:407-409.
    • (1975) J Neurochem , vol.24 , pp. 407-409
    • Fonnum, F.1
  • 18
    • 0015936071 scopus 로고
    • Choline uptake systems of rat brain synaptosomes
    • Haga T, Noda H (1973) Choline uptake systems of rat brain synaptosomes. Biochim Biophys Acta 291:564-575.
    • (1973) Biochim Biophys Acta , vol.291 , pp. 564-575
    • Haga, T.1    Noda, H.2
  • 19
    • 0018591944 scopus 로고
    • High affinity choline transport and acetylCoA production in brain and their roles in the regulation of acetylcholine synthesis
    • Jope RS (1979) High affinity choline transport and acetylCoA production in brain and their roles in the regulation of acetylcholine synthesis. Brain Res Brain Res Rev 1:313-344.
    • (1979) Brain Res Brain Res Rev , vol.1 , pp. 313-344
    • Jope, R.S.1
  • 20
    • 0025111206 scopus 로고
    • Small rises in plasma choline reverse the negative arteriovenous difference of brain choline
    • Klein J, Köppen A, Löffelholz K (1990) Small rises in plasma choline reverse the negative arteriovenous difference of brain choline. J Neurochem 55:1231-1236.
    • (1990) J Neurochem , vol.55 , pp. 1231-1236
    • Klein, J.1    Köppen, A.2    Löffelholz, K.3
  • 21
    • 0016466847 scopus 로고
    • Effect of choline acetyltransferase inhibitors on mouse and guinea-pig brain choline and acetylcholine
    • Krell RD, Goldberg AM (1975) Effect of choline acetyltransferase inhibitors on mouse and guinea-pig brain choline and acetylcholine. Biochem Pharmacol 24:391-396.
    • (1975) Biochem Pharmacol , vol.24 , pp. 391-396
    • Krell, R.D.1    Goldberg, A.M.2
  • 22
    • 0015578427 scopus 로고
    • Choline: Selective accumulation by central cholinergic neurons
    • Kuhar MJ, Sethy VH, Roth RH, Aghajanian GK (1973) Choline: selective accumulation by central cholinergic neurons. J Neurochem 20:581-593.
    • (1973) J Neurochem , vol.20 , pp. 581-593
    • Kuhar, M.J.1    Sethy, V.H.2    Roth, R.H.3    Aghajanian, G.K.4
  • 24
    • 0023203084 scopus 로고
    • In vivo synthesis of phosphatidylcholine in rat brain via the phospholipid methylation pathway
    • Lakher M, Wurtman RJ (1987) In vivo synthesis of phosphatidylcholine in rat brain via the phospholipid methylation pathway. Brain Res 419:131-140.
    • (1987) Brain Res , vol.419 , pp. 131-140
    • Lakher, M.1    Wurtman, R.J.2
  • 25
    • 0027490717 scopus 로고
    • Phospholipase D-catalyzed hydrolysis of phosphatidylcholine provides the choline precursor for acetylcholine synthesis in a human neuronal cell line
    • Lee H-C, Fellenz-Maloney M-P, Liscovitch M, Blusztajn JK (1993) Phospholipase D-catalyzed hydrolysis of phosphatidylcholine provides the choline precursor for acetylcholine synthesis in a human neuronal cell line. Proc Natl Acad Sci USA 90:10086-10090.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10086-10090
    • Lee, H.-C.1    Fellenz-Maloney, M.-P.2    Liscovitch, M.3    Blusztajn, J.K.4
  • 27
    • 0020262123 scopus 로고
    • The activation of presynaptic choline uptake by acetylcholine release
    • Marchbanks RM (1982) The activation of presynaptic choline uptake by acetylcholine release. J Physiol (Paris) 78:373-378.
    • (1982) J Physiol (Paris) , vol.78 , pp. 373-378
    • Marchbanks, R.M.1
  • 28
    • 0035898265 scopus 로고    scopus 로고
    • Distribution of the high-affinity choline transporter in the central nervous system of the rat
    • Misawa H, Nakata K, Matsuura J, Nagao M, Okuda T, Haga T (2001) Distribution of the high-affinity choline transporter in the central nervous system of the rat. Neuroscience 105:87-98.
    • (2001) Neuroscience , vol.105 , pp. 87-98
    • Misawa, H.1    Nakata, K.2    Matsuura, J.3    Nagao, M.4    Okuda, T.5    Haga, T.6
  • 29
    • 0037079059 scopus 로고    scopus 로고
    • Roles of neurotransmitter in synapse formation: Development of neuromuscular junctions lacking choline acetyltransferase
    • Misgeld T, Burgess RW, Lewis RM, Cunningham JM, Lichtman JW, Sanes JR (2002) Roles of neurotransmitter in synapse formation: development of neuromuscular junctions lacking choline acetyltransferase. Neuron 36:635-648.
    • (2002) Neuron , vol.36 , pp. 635-648
    • Misgeld, T.1    Burgess, R.W.2    Lewis, R.M.3    Cunningham, J.M.4    Lichtman, J.W.5    Sanes, J.R.6
  • 30
    • 0017183362 scopus 로고
    • Activation of high-affinity choline uptake in vitro by depolarizing agents
    • Murrin LC, Kuhar MJ (1976) Activation of high-affinity choline uptake in vitro by depolarizing agents. Mol Pharmacol 12:1082-1090.
    • (1976) Mol Pharmacol , vol.12 , pp. 1082-1090
    • Murrin, L.C.1    Kuhar, M.J.2
  • 32
    • 0034004554 scopus 로고    scopus 로고
    • Identification and characterization of the high-affinity choline transporter
    • Okuda T, Haga T, Kanai Y, Endou H, Ishihara T, Katsura I (2000) Identification and characterization of the high-affinity choline transporter. Nat Neurosci 3:120-125.
    • (2000) Nat Neurosci , vol.3 , pp. 120-125
    • Okuda, T.1    Haga, T.2    Kanai, Y.3    Endou, H.4    Ishihara, T.5    Katsura, I.6
  • 33
    • 0037160130 scopus 로고    scopus 로고
    • Single nucleotide polymorphism of the human high-affinity choline transporter alters transport rate
    • Okuda T, Okamura M, Kaitsuka C, Haga T, Gurwitz D (2002) Single nucleotide polymorphism of the human high-affinity choline transporter alters transport rate. J Biol Chem 277:45315-45322.
    • (2002) J Biol Chem , vol.277 , pp. 45315-45322
    • Okuda, T.1    Okamura, M.2    Kaitsuka, C.3    Haga, T.4    Gurwitz, D.5
  • 34
    • 0017600519 scopus 로고
    • Transport of metabolic substrates through the blood-brain barrier
    • Pardridge WM, Oldendorf WH (1977) Transport of metabolic substrates through the blood-brain barrier. J Neurochem 28:5-12.
    • (1977) J Neurochem , vol.28 , pp. 5-12
    • Pardridge, W.M.1    Oldendorf, W.H.2
  • 35
    • 0032887825 scopus 로고    scopus 로고
    • Intraparenchymal infusions of 192 IgG-saporin: Development of a method for selective and discrete lesioning of cholinergic basal forebrain nuclei
    • Pizzo DP, Waite JJ, Thal LJ, Winkler J (1999) Intraparenchymal infusions of 192 IgG-saporin: development of a method for selective and discrete lesioning of cholinergic basal forebrain nuclei. J Neurosci Methods 91:9-19.
    • (1999) J Neurosci Methods , vol.91 , pp. 9-19
    • Pizzo, D.P.1    Waite, J.J.2    Thal, L.J.3    Winkler, J.4
  • 36
    • 0017662564 scopus 로고
    • Acetylcholine metabolism and choline uptake in cortical slices
    • Polak RL, Molenaar PC, van Gelder M (1977) Acetylcholine metabolism and choline uptake in cortical slices. J Neurochem 29:477-485.
    • (1977) J Neurochem , vol.29 , pp. 477-485
    • Polak, R.L.1    Molenaar, P.C.2    Van Gelder, M.3
  • 37
    • 0018941733 scopus 로고
    • Relation between the content of acetyl-coenzyme A and acetylcholine in brain slices
    • Ricny J, Tucek S (1980) Relation between the content of acetyl-coenzyme A and acetylcholine in brain slices. Biochem J 188:683-688.
    • (1980) Biochem J , vol.188 , pp. 683-688
    • Ricny, J.1    Tucek, S.2
  • 38
    • 0018079027 scopus 로고
    • High affinity choline uptake in striatum and hippocampus: Differential effects of treatments which release acetylcholine
    • Sherman KA, Zigmond MJ, Hanin I (1978) High affinity choline uptake in striatum and hippocampus: differential effects of treatments which release acetylcholine. Life Sci 23:1863-1870.
    • (1978) Life Sci , vol.23 , pp. 1863-1870
    • Sherman, K.A.1    Zigmond, M.J.2    Hanin, I.3
  • 39
    • 0017235493 scopus 로고
    • Sodium-dependent high affinity choline uptake: A regulatory step in the synthesis of acetylcholine
    • Simon JR, Atweh S, Kuhar MJ (1976) Sodium-dependent high affinity choline uptake: a regulatory step in the synthesis of acetylcholine. J Neurochem 26:909-922.
    • (1976) J Neurochem , vol.26 , pp. 909-922
    • Simon, J.R.1    Atweh, S.2    Kuhar, M.J.3
  • 41
    • 0141884378 scopus 로고    scopus 로고
    • Changes in cortical acetyl-CoA metabolism after selective basal forebrain cholinergic degeneration by 192IgG-saporin
    • Tomaszewicz M, Rossner S, Schliebs R, Cwikowska J, Szutowicz A (2003) Changes in cortical acetyl-CoA metabolism after selective basal forebrain cholinergic degeneration by 192IgG-saporin. J Neurochem 87:318-324.
    • (2003) J Neurochem , vol.87 , pp. 318-324
    • Tomaszewicz, M.1    Rossner, S.2    Schliebs, R.3    Cwikowska, J.4    Szutowicz, A.5
  • 42
    • 0025119804 scopus 로고
    • The synthesis of acetylcholine: Twenty years of progress
    • Tucek S (1990) The synthesis of acetylcholine: twenty years of progress. Prog Brain Res 84:467-477.
    • (1990) Prog Brain Res , vol.84 , pp. 467-477
    • Tucek, S.1
  • 44
    • 0242577796 scopus 로고    scopus 로고
    • Phosphatidylethanolamine-N-methyltransferase activity and dietary choline regulate liver-plasma lipid flux and essential fatty acid metabolism in mice
    • Watkins SM, Zhu X, Zeisel SH (2003) Phosphatidylethanolamine-N- methyltransferase activity and dietary choline regulate liver-plasma lipid flux and essential fatty acid metabolism in mice. J Nutr 133:3386-3391.
    • (2003) J Nutr , vol.133 , pp. 3386-3391
    • Watkins, S.M.1    Zhu, X.2    Zeisel, S.H.3
  • 45
    • 0022474319 scopus 로고
    • Cholinergic function and memory: Extensive inhibition of choline acetyltransferase fails to impair radial maze performance in rats
    • Wenk G, Sweeney J, Hughey D, Carson J, Olton D (1986) Cholinergic function and memory: extensive inhibition of choline acetyltransferase fails to impair radial maze performance in rats. Pharmacol Biochem Behav 25:521-526.
    • (1986) Pharmacol Biochem Behav , vol.25 , pp. 521-526
    • Wenk, G.1    Sweeney, J.2    Hughey, D.3    Carson, J.4    Olton, D.5
  • 47
    • 0015721255 scopus 로고
    • High affinity transport of choline into synaptosomes of rat brain
    • Yamamura HI, Snyder SH (1973) High affinity transport of choline into synaptosomes of rat brain. J Neurochem 21:1355-1374.
    • (1973) J Neurochem , vol.21 , pp. 1355-1374
    • Yamamura, H.I.1    Snyder, S.H.2
  • 48
    • 0035789153 scopus 로고    scopus 로고
    • Generation of choline for acetylcholine synthesis by phospholipase D isoforms
    • Zhao D, Frohman MA, Blusztajn JK (2001) Generation of choline for acetylcholine synthesis by phospholipase D isoforms. BMC Neurosci 2:16.
    • (2001) BMC Neurosci , vol.2 , pp. 16
    • Zhao, D.1    Frohman, M.A.2    Blusztajn, J.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.