A variant at 9p21.3 functionally implicates CDKN2B in paediatric B-cell precursor acute lymphoblastic leukaemia aetiology

Nature Communications

Volumn 7, Issue , 2016, Pages

  Hungate, Eric A ^a   Vora, Sapana R ^a   Gamazon, Eric R ^b,c   Moriyama, Takaya ^d   Best, Timothy ^a   Hulur, Imge ^a   Lee, Younghee ^b   Evans, Tiffany Jane ^e   Ellinghaus, Eva ^f   Stanulla, Martin ^g   Rudant, Jéremie ^h   Orsi, Laurent ^h   Clavel, Jacqueline ^h,i   Milne, Elizabeth ^j   Scott, Rodney J ^e,k   Pui, Ching Hon ^d   Cox, Nancy J ^b   Loh, Mignon L ^l   Yang, Jun J ^d   Skol, Andrew D ^a   Onel, Kenan ^a   more..

^a UNIVERSITY OF CHICAGO   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^e UNIVERSITY OF NEWCASTLE   (Australia)

^f UNIVERSITY OF KIEL   (Germany)

^g UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^h PARIS DESCARTES UNIVERSITY   (France)

ⁱ National Registry of Childhood Hematological Malignancies   (France)

^j UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^k JOHN HUNTER HOSPITAL   (Australia)

^l UNIVERSITY OF CALIFORNIA   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2B; CDKN2B PROTEIN, HUMAN;

AFRICAN AMERICAN; ALLELE; CANCER; CELLS AND CELL COMPONENTS; CHILD HEALTH; CYTOGENETICS; DISEASE CONTROL; ETIOLOGY; GENE EXPRESSION;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; AFRICAN AMERICAN; ALLELE; ARTICLE; CANCER RISK; CHILD; CHILDHOOD LEUKEMIA; CHROMOSOME 9P; COHORT ANALYSIS; CONTROLLED STUDY; EUROPEAN; EXON; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENE LOCUS; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRE B LYMPHOCYTE; QUANTITATIVE TRAIT LOCUS; RNA SEQUENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SPLICING REGULATORY ELEMENT; CASE CONTROL STUDY; CAUCASIAN; CHROMOSOMAL MAPPING; CHROMOSOME 9; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HISPANIC; INFANT; PRESCHOOL CHILD;

EUROPE;

AFRICAN AMERICANS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 9; CYCLIN-DEPENDENT KINASE INHIBITOR P15; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HISPANIC AMERICANS; HUMANS; INFANT; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; PRECURSOR B-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA;

EID: 84958225502     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10635     Document Type: Article

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