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Volumn 1865, Issue 2, 2016, Pages 168-175

The role of immune system exhaustion on cancer cell escape and anti-tumor immune induction after irradiation

Author keywords

Acquire; Cancer; Immune system; Innate; Natural Killer cells; Regulator T cells

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 6; MEMBRANE PROTEIN; PROGRAMMED DEATH 1 RECEPTOR; T CELL IMMUNOGLOBULIN DOMAIN AND MUCIN DOMAIN 3; TUMOR ANTIGEN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

EID: 84958206655     PISSN: 0304419X     EISSN: 18792561     Source Type: Journal    
DOI: 10.1016/j.bbcan.2016.02.002     Document Type: Review
Times cited : (28)

References (60)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D., Weinberg R.a. Hallmarks of cancer: the next generation. Cell 2011, 144(5):646-674. 10.1016/j.cell.2011.02.013.
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.2
  • 2
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion
    • Schreiber R.D., Old L.J., Smyth M.J. Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science (New York, N.Y.) 2011, 331(6024):1565-1570. 10.1126/science.1203486.
    • (2011) Science (New York, N.Y.) , vol.331 , Issue.6024 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 3
    • 59449085264 scopus 로고    scopus 로고
    • Targeting inflammatory pathways for prevention and therapy of cancer: short-term friend, long-term foe
    • Aggarwal B.B., Vijayalekshmi R.V., Sung B. Targeting inflammatory pathways for prevention and therapy of cancer: short-term friend, long-term foe. Clin. Cancer Res. 2009, 15(2):425-430. 10.1158/1078-0432.CCR-08-0149.
    • (2009) Clin. Cancer Res. , vol.15 , Issue.2 , pp. 425-430
    • Aggarwal, B.B.1    Vijayalekshmi, R.V.2    Sung, B.3
  • 4
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov S.I., Greten F.R., Karin M. Immunity, inflammation, and cancer. Cell 2010, 140(6):883-899. 10.1016/j.cell.2010.01.025.
    • (2010) Cell , vol.140 , Issue.6 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 5
    • 79952996039 scopus 로고    scopus 로고
    • Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage
    • Grivennikov S.I., Karin M. Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage. Ann. Rheum. Dis. 2011, 70(Suppl. 1):i104-i108. 10.1136/ard.2010.140145.
    • (2011) Ann. Rheum. Dis. , vol.70 , pp. i104-i108
    • Grivennikov, S.I.1    Karin, M.2
  • 7
    • 34047220868 scopus 로고    scopus 로고
    • Cancer immunoediting from immune surveillance to immune escape
    • Kim R., Emi M., Tanabe K. Cancer immunoediting from immune surveillance to immune escape. Immunology 2007, 121:1-14. 10.1111/j.1365-2567.2007.02587.x.
    • (2007) Immunology , vol.121 , pp. 1-14
    • Kim, R.1    Emi, M.2    Tanabe, K.3
  • 9
    • 85016864689 scopus 로고    scopus 로고
    • Cancer dormancy: a regulatory role for endogenous immunity in establishing and maintaining the tumor dormant state
    • Baxevanis C., Perez S. Cancer dormancy: a regulatory role for endogenous immunity in establishing and maintaining the tumor dormant state. Vaccine 2015, 3(3):597-619. 10.3390/vaccines3030597.
    • (2015) Vaccine , vol.3 , Issue.3 , pp. 597-619
    • Baxevanis, C.1    Perez, S.2
  • 10
    • 67649359533 scopus 로고    scopus 로고
    • Systemic effects of local radiotherapy
    • Formenti S.C., Demaria S. Systemic effects of local radiotherapy. Lancet Oncol. 2009, 10(7):718-726. 10.1016/S1470-2045(09)70082-8.
    • (2009) Lancet Oncol. , vol.10 , Issue.7 , pp. 718-726
    • Formenti, S.C.1    Demaria, S.2
  • 11
    • 84926528302 scopus 로고    scopus 로고
    • Overcoming T cell exhaustion in infection and cancer
    • Pauken K.E., Wherry E.J. Overcoming T cell exhaustion in infection and cancer. Trends Immunol. 2015, 36(4):265-276. 10.1016/j.it.2015.02.008.
    • (2015) Trends Immunol. , vol.36 , Issue.4 , pp. 265-276
    • Pauken, K.E.1    Wherry, E.J.2
  • 13
    • 84943415051 scopus 로고    scopus 로고
    • Springer Berlin Heidelberg, Berlin, Heidelberg, N. Rezaei (Ed.)
    • Cancer Immunology 2015, Springer Berlin Heidelberg, Berlin, Heidelberg. 10.1007/978-3-662-44006-3. N. Rezaei (Ed.).
    • (2015) Cancer Immunology
  • 14
    • 79953749145 scopus 로고    scopus 로고
    • The unholy trinity: inflammation, cytokines, and STAT3 shape the cancer microenvironment
    • Li N., Grivennikov S.I., Karin M. The unholy trinity: inflammation, cytokines, and STAT3 shape the cancer microenvironment. Cancer Cell 2011, 19(4):429-431. 10.1016/j.ccr.2011.03.018.
    • (2011) Cancer Cell , vol.19 , Issue.4 , pp. 429-431
    • Li, N.1    Grivennikov, S.I.2    Karin, M.3
  • 16
    • 67349162130 scopus 로고    scopus 로고
    • Tumour necrosis factor and cancer
    • Balkwill F. Tumour necrosis factor and cancer. Nat. Rev. Cancer 2009, 9(5):361-371. 10.1038/nrc2628.
    • (2009) Nat. Rev. Cancer , vol.9 , Issue.5 , pp. 361-371
    • Balkwill, F.1
  • 17
    • 70350500225 scopus 로고    scopus 로고
    • STATs in cancer inflammation and immunity: a leading role for STAT3
    • Yu H., Pardoll D., Jove R. STATs in cancer inflammation and immunity: a leading role for STAT3. Nat. Rev. Cancer 2009, 9(11):798-809. 10.1038/nrc2734.
    • (2009) Nat. Rev. Cancer , vol.9 , Issue.11 , pp. 798-809
    • Yu, H.1    Pardoll, D.2    Jove, R.3
  • 18
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: back to Virchow?
    • Balkwill F., Mantovani A. Inflammation and cancer: back to Virchow?. Lancet 2001, 357(9255):539-545. 10.1016/S0140-6736(00)04046-0.
    • (2001) Lancet , vol.357 , Issue.9255 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 19
    • 77955928161 scopus 로고    scopus 로고
    • Tumors as organs: complex tissues that interface with the entire organism
    • Egeblad M., Nakasone E.S., Werb Z. Tumors as organs: complex tissues that interface with the entire organism. Dev. Cell 2010, 18(6):884-901. 10.1016/j.devcel.2010.05.012.
    • (2010) Dev. Cell , vol.18 , Issue.6 , pp. 884-901
    • Egeblad, M.1    Nakasone, E.S.2    Werb, Z.3
  • 20
    • 79958189573 scopus 로고    scopus 로고
    • In situ immune response after neoadjuvant chemotherapy for breast cancer predicts survival
    • Ladoire S., Mignot G., Dabakuyo S., Arnould L., Apetoh L., Rébé C., Ghiringhelli F. In situ immune response after neoadjuvant chemotherapy for breast cancer predicts survival. J. Pathol. 2011, 224(3):389-400. 10.1002/path.2866.
    • (2011) J. Pathol. , vol.224 , Issue.3 , pp. 389-400
    • Ladoire, S.1    Mignot, G.2    Dabakuyo, S.3    Arnould, L.4    Apetoh, L.5    Rébé, C.6    Ghiringhelli, F.7
  • 22
    • 73349142719 scopus 로고    scopus 로고
    • In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer
    • Pages F., Kirilovsky A., Mlecnik B., Asslaber M., Tosolini M., Bindea G., Galon J. In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer. J. Clin. Oncol. 2009, 27(35):5944-5951. 10.1200/JCO.2008.19.6147.
    • (2009) J. Clin. Oncol. , vol.27 , Issue.35 , pp. 5944-5951
    • Pages, F.1    Kirilovsky, A.2    Mlecnik, B.3    Asslaber, M.4    Tosolini, M.5    Bindea, G.6    Galon, J.7
  • 23
    • 65549133014 scopus 로고    scopus 로고
    • Coordination of intratumoral immune reaction and human colorectal cancer recurrence
    • Camus M., Tosolini M., Mlecnik B., Pages F., Kirilovsky A., Berger A., Galon J. Coordination of intratumoral immune reaction and human colorectal cancer recurrence. Cancer Res. 2009, 69(6):2685-2693. 10.1158/0008-5472.CAN-08-2654.
    • (2009) Cancer Res. , vol.69 , Issue.6 , pp. 2685-2693
    • Camus, M.1    Tosolini, M.2    Mlecnik, B.3    Pages, F.4    Kirilovsky, A.5    Berger, A.6    Galon, J.7
  • 25
    • 79952537676 scopus 로고    scopus 로고
    • The tumor-immune microenvironment and response to radiation therapy
    • Shiao S.L., Coussens L.M. The tumor-immune microenvironment and response to radiation therapy. J. Mammary Gland Biol. Neoplasia 2010, 15(4):411-421. 10.1007/s10911-010-9194-9.
    • (2010) J. Mammary Gland Biol. Neoplasia , vol.15 , Issue.4 , pp. 411-421
    • Shiao, S.L.1    Coussens, L.M.2
  • 26
    • 58149213871 scopus 로고    scopus 로고
    • Behavior of immune players in the tumor microenvironment
    • Pittet M.J. Behavior of immune players in the tumor microenvironment. Curr. Opin. Oncol. 2009, 21(1):53-59. 10.1097/CCO.0b013e32831bc38a.
    • (2009) Curr. Opin. Oncol. , vol.21 , Issue.1 , pp. 53-59
    • Pittet, M.J.1
  • 30
    • 77949425341 scopus 로고    scopus 로고
    • Regulatory T cells and immune tolerance to tumors
    • Cao X. Regulatory T cells and immune tolerance to tumors. Immunol. Res. 2009, 46(1-3):79-93. 10.1007/s12026-009-8124-7.
    • (2009) Immunol. Res. , vol.46 , Issue.1-3 , pp. 79-93
    • Cao, X.1
  • 31
    • 77951448800 scopus 로고    scopus 로고
    • Intratumoral forkhead box P3-positive regulatory T cells predict poor survival in cyclooxygenase-2-positive uveal melanoma
    • Mougiakakos D., Johansson C.C., Trocme E., All-Ericsson C., Economou M.A., Larsson O., Kiessling R. Intratumoral forkhead box P3-positive regulatory T cells predict poor survival in cyclooxygenase-2-positive uveal melanoma. Cancer 2010, 116(9):2224-2233. 10.1002/cncr.24999.
    • (2010) Cancer , vol.116 , Issue.9 , pp. 2224-2233
    • Mougiakakos, D.1    Johansson, C.C.2    Trocme, E.3    All-Ericsson, C.4    Economou, M.A.5    Larsson, O.6    Kiessling, R.7
  • 32
    • 84896704750 scopus 로고    scopus 로고
    • Homeostatic control of regulatory T cell diversity
    • Liston A., Gray D.H.D. Homeostatic control of regulatory T cell diversity. Nat. Rev. Immunol. 2014, 14(3):154-165. 10.1038/nri3605.
    • (2014) Nat. Rev. Immunol. , vol.14 , Issue.3 , pp. 154-165
    • Liston, A.1    Gray, D.H.D.2
  • 34
    • 77950794689 scopus 로고    scopus 로고
    • Multiple antitumor mechanisms downstream of prophylactic regulatory T-cell depletion
    • Teng M.W.L., Swann J.B., von Scheidt B., Sharkey J., Zerafa N., McLaughlin N., Smyth M.J. Multiple antitumor mechanisms downstream of prophylactic regulatory T-cell depletion. Cancer Res. 2010, 70(7):2665-2674. 10.1158/0008-5472.CAN-09-1574.
    • (2010) Cancer Res. , vol.70 , Issue.7 , pp. 2665-2674
    • Teng, M.W.L.1    Swann, J.B.2    von Scheidt, B.3    Sharkey, J.4    Zerafa, N.5    McLaughlin, N.6    Smyth, M.J.7
  • 35
    • 84926059486 scopus 로고    scopus 로고
    • Radiation meets immunotherapy - a perfect match in the era of combination therapy?
    • Soukup K., Wang X. Radiation meets immunotherapy - a perfect match in the era of combination therapy?. Int. J. Radiat. Biol. 2015, 91(4):299-305. 10.3109/09553002.2014.995383.
    • (2015) Int. J. Radiat. Biol. , vol.91 , Issue.4 , pp. 299-305
    • Soukup, K.1    Wang, X.2
  • 36
    • 79952721606 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin fosters human breast tumor growth by promoting type 2 inflammation
    • Pedroza-Gonzalez A., Xu K., Wu T.-C., Aspord C., Tindle S., Marches F., Palucka A.K. Thymic stromal lymphopoietin fosters human breast tumor growth by promoting type 2 inflammation. J. Exp. Med. 2011, 208(3):479-490. 10.1084/jem.20102131.
    • (2011) J. Exp. Med. , vol.208 , Issue.3 , pp. 479-490
    • Pedroza-Gonzalez, A.1    Xu, K.2    Wu, T.-C.3    Aspord, C.4    Tindle, S.5    Marches, F.6    Palucka, A.K.7
  • 37
    • 84876494033 scopus 로고    scopus 로고
    • Exhausting T cells in CLL
    • Zenz T. Exhausting T cells in CLL. Blood 2013, 121(9):1485-1486. 10.1182/blood-2013-01-475939.
    • (2013) Blood , vol.121 , Issue.9 , pp. 1485-1486
    • Zenz, T.1
  • 38
    • 84921277700 scopus 로고    scopus 로고
    • T cell exhaustion and interleukin 2 downregulation
    • Balkhi M.Y., Ma Q., Ahmad S., Junghans R.P. T cell exhaustion and interleukin 2 downregulation. Cytokine 2015, 71(2):339-347. 10.1016/j.cyto.2014.11.024.
    • (2015) Cytokine , vol.71 , Issue.2 , pp. 339-347
    • Balkhi, M.Y.1    Ma, Q.2    Ahmad, S.3    Junghans, R.P.4
  • 39
    • 1842562212 scopus 로고    scopus 로고
    • Tolerance and cancer: mechanisms of tumor evasion and strategies for breaking tolerance
    • Mapara M.Y., Sykes M. Tolerance and cancer: mechanisms of tumor evasion and strategies for breaking tolerance. J. Clin. Oncol. Off. J. Am. Soc. Clin. Oncol. 2004, 22(6):1136-1151. 10.1200/JCO.2004.10.041.
    • (2004) J. Clin. Oncol. Off. J. Am. Soc. Clin. Oncol. , vol.22 , Issue.6 , pp. 1136-1151
    • Mapara, M.Y.1    Sykes, M.2
  • 40
    • 77953540361 scopus 로고    scopus 로고
    • Epigenomics of T cell activation, differentiation, and memory
    • Cuddapah S., Barski A., Zhao K. Epigenomics of T cell activation, differentiation, and memory. Curr. Opin. Immunol. 2010, 22(3):341-347. 10.1016/j.coi.2010.02.007.
    • (2010) Curr. Opin. Immunol. , vol.22 , Issue.3 , pp. 341-347
    • Cuddapah, S.1    Barski, A.2    Zhao, K.3
  • 41
    • 70349569569 scopus 로고    scopus 로고
    • Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-and are functionally impaired
    • Ahmadzadeh M., Johnson L.A., Heemskerk B., Wunderlich J.R., Dudley M.E., White D.E., Rosenberg S.A. Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-and are functionally impaired. Blood 2009, 114(8):1537-1544. 10.1182/blood-2008-12-195792.
    • (2009) Blood , vol.114 , Issue.8 , pp. 1537-1544
    • Ahmadzadeh, M.1    Johnson, L.A.2    Heemskerk, B.3    Wunderlich, J.R.4    Dudley, M.E.5    White, D.E.6    Rosenberg, S.A.7
  • 44
    • 77957744369 scopus 로고    scopus 로고
    • Targeting Tim-and PD-pathways to reverse T cell exhaustion and restore anti-tumor immunity
    • Sakuishi K., Apetoh L., Sullivan J.M., Blazar B.R., Kuchroo V.K., Anderson A.C. Targeting Tim-and PD-pathways to reverse T cell exhaustion and restore anti-tumor immunity. J. Exp. Med. 2010, 207(10):2187-2194. 10.1084/jem.20100643.
    • (2010) J. Exp. Med. , vol.207 , Issue.10 , pp. 2187-2194
    • Sakuishi, K.1    Apetoh, L.2    Sullivan, J.M.3    Blazar, B.R.4    Kuchroo, V.K.5    Anderson, A.C.6
  • 45
    • 84989961626 scopus 로고    scopus 로고
    • PD-1(hi)TIM-3(+) T cells associate with and predict leukemia relapse in AML patients post allogeneic stem cell transplantation
    • Kong Y., Zhang J., Claxton D.F., Ehmann W.C., Rybka W.B., Zhu L., Zheng H. PD-1(hi)TIM-3(+) T cells associate with and predict leukemia relapse in AML patients post allogeneic stem cell transplantation. Blood Cancer J. 2015, 5. 10.1038/bcj.2015.58.
    • (2015) Blood Cancer J. , vol.5
    • Kong, Y.1    Zhang, J.2    Claxton, D.F.3    Ehmann, W.C.4    Rybka, W.B.5    Zhu, L.6    Zheng, H.7
  • 46
    • 84983168646 scopus 로고    scopus 로고
    • Advances in radiation oncology in lung cancer
    • Springer, Berlin/Heidelberg, J. Branislav (Ed.)
    • Jeremic B. Advances in radiation oncology in lung cancer. Radiation Oncology 2005, 121. Springer, Berlin/Heidelberg. Second Edi., 10.1007/b137825. J. Branislav (Ed.).
    • (2005) Radiation Oncology , vol.121
    • Jeremic, B.1
  • 47
    • 31444439350 scopus 로고    scopus 로고
    • Concurrent infiltration by CD8+ T cells and CD4+ T cells is a favourable prognostic factor in non-small-cell lung carcinoma
    • January
    • Hiraoka K., Miyamoto M., Cho Y., Suzuoki M., Oshikiri T., Nakakubo Y., Katoh H. Concurrent infiltration by CD8+ T cells and CD4+ T cells is a favourable prognostic factor in non-small-cell lung carcinoma. Br. J. Cancer 2006, 94(January):275-280. 10.1038/sj.bjc.6602934.
    • (2006) Br. J. Cancer , vol.94 , pp. 275-280
    • Hiraoka, K.1    Miyamoto, M.2    Cho, Y.3    Suzuoki, M.4    Oshikiri, T.5    Nakakubo, Y.6    Katoh, H.7
  • 48
    • 84875888194 scopus 로고    scopus 로고
    • CD4/CD8 co-expression shows independent prognostic impact in resected non-small cell lung cancer patients treated with adjuvant radiotherapy
    • Hald S.M., Bremnes R.M., Al-Shibli K., Al-Saad S., Andersen S., Stenvold H., Donnem T. CD4/CD8 co-expression shows independent prognostic impact in resected non-small cell lung cancer patients treated with adjuvant radiotherapy. Lung Cancer (Amsterdam, Netherlands) 2013, 80(2):209-215. 10.1016/j.lungcan.2012.12.026.
    • (2013) Lung Cancer (Amsterdam, Netherlands) , vol.80 , Issue.2 , pp. 209-215
    • Hald, S.M.1    Bremnes, R.M.2    Al-Shibli, K.3    Al-Saad, S.4    Andersen, S.5    Stenvold, H.6    Donnem, T.7
  • 49
    • 84949548456 scopus 로고    scopus 로고
    • Radio-immunotherapy-induced immunogenic cancer cells as basis for induction of systemic anti-tumor immune responses - pre-clinical evidence and ongoing clinical applications
    • Derer A., Deloch L., Rubner Y., Fietkau R., Frey B., Gaipl U.S. Radio-immunotherapy-induced immunogenic cancer cells as basis for induction of systemic anti-tumor immune responses - pre-clinical evidence and ongoing clinical applications. Front. Immunol. 2015, 6:505. 10.3389/fimmu.2015.00505.
    • (2015) Front. Immunol. , vol.6 , pp. 505
    • Derer, A.1    Deloch, L.2    Rubner, Y.3    Fietkau, R.4    Frey, B.5    Gaipl, U.S.6
  • 52
    • 77950366886 scopus 로고    scopus 로고
    • Decoding cell death signals in inflammation and immunity
    • Zitvogel L., Kepp O., Kroemer G. Decoding cell death signals in inflammation and immunity. Cell 2010, 140(6):798-804. 10.1016/j.cell.2010.02.015.
    • (2010) Cell , vol.140 , Issue.6 , pp. 798-804
    • Zitvogel, L.1    Kepp, O.2    Kroemer, G.3
  • 55
    • 0031132876 scopus 로고    scopus 로고
    • Heat shock protein 72 on tumor cells: a recognition structure for natural killer cells
    • (Baltimore, Md.: 1950)
    • Multhoff G., Botzler C., Jennen L., Schmidt J., Ellwart J., Issels R. Heat shock protein 72 on tumor cells: a recognition structure for natural killer cells. J. Immunol. 1997, 158(9):4341-4350. (Baltimore, Md.: 1950).
    • (1997) J. Immunol. , vol.158 , Issue.9 , pp. 4341-4350
    • Multhoff, G.1    Botzler, C.2    Jennen, L.3    Schmidt, J.4    Ellwart, J.5    Issels, R.6
  • 56
    • 76649097628 scopus 로고    scopus 로고
    • Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells
    • Chalmin F., Ladoire S., Mignot G., Vincent J., Bruchard M., Remy-Martin J.-P., Ghiringhelli F. Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells. J. Clin. Invest. 2010, 120(2):457-471. 10.1172/JCI40483.
    • (2010) J. Clin. Invest. , vol.120 , Issue.2 , pp. 457-471
    • Chalmin, F.1    Ladoire, S.2    Mignot, G.3    Vincent, J.4    Bruchard, M.5    Remy-Martin, J.-P.6    Ghiringhelli, F.7
  • 57
    • 78049397567 scopus 로고    scopus 로고
    • Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I
    • Murshid A., Gong J., Calderwood S.K. Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I. J. Immunol. 2010, 185(5):2903-2917. 10.4049/jimmunol.0903635.
    • (2010) J. Immunol. , vol.185 , Issue.5 , pp. 2903-2917
    • Murshid, A.1    Gong, J.2    Calderwood, S.K.3
  • 58
    • 77953946258 scopus 로고    scopus 로고
    • The endogenous danger signals HSP70 and MICA cooperate in the activation of cytotoxic effector functions of NK cells
    • Elsner L., Flügge P.F., Lozano J., Muppala V., Eiz-Vesper B., Demiroglu S.Y., Dressel R. The endogenous danger signals HSP70 and MICA cooperate in the activation of cytotoxic effector functions of NK cells. J. Cell. Mol. Med. 2010, 14(4):992-1002. 10.1111/j.1582-4934.2008.00677.x.
    • (2010) J. Cell. Mol. Med. , vol.14 , Issue.4 , pp. 992-1002
    • Elsner, L.1    Flügge, P.F.2    Lozano, J.3    Muppala, V.4    Eiz-Vesper, B.5    Demiroglu, S.Y.6    Dressel, R.7
  • 60
    • 84883787417 scopus 로고    scopus 로고
    • Immunologically augmented cancer treatment using modern radiotherapy
    • Elsevier Ltd.
    • Durante M., Reppingen N., Held K.D. Immunologically augmented cancer treatment using modern radiotherapy. 19 Trends in Molecular Medicine 2013, 565-582. Elsevier Ltd. 10.1016/j.molmed.2013.05.007.
    • (2013) 19 Trends in Molecular Medicine
    • Durante, M.1    Reppingen, N.2    Held, K.D.3


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