Heat Shock Protein 72 on Tumor Cells: A Recognition Structure for Natural Killer Cells

Journal of Immunology

Volumn 158, Issue 9, 1997, Pages 4341-4350

  Multhoff, Gabriele ^a,d   Botzler, Claus ^c   Jennen, Luise ^b   Schmidt, Jörg ^b   Ellwart, Joachim ^a   Issels, Rolf ^a,c  

^a National Research Center for Environment and Health   (Germany)

^b Natl Res Ctr Environ and Hlth   (Germany)

^c LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^d Institute for Clinical Hematology   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 72; MEMBRANE ANTIGEN;

ARTICLE; CARCINOMA; CELL CULTURE; CELL CYCLE; CELL MEMBRANE; CELLULAR IMMUNITY; COLON TUMOR; CYTOTOXICITY; FLOW CYTOMETRY; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; NATURAL KILLER CELL; PATHOLOGY;

ANTIGENS, SURFACE; CARCINOMA; CELL CYCLE; CELL MEMBRANE; COLONIC NEOPLASMS; CYTOTOXICITY, IMMUNOLOGIC; FLOW CYTOMETRY; HEAT-SHOCK PROTEINS; HSP72 HEAT-SHOCK PROTEINS; HUMANS; IMMUNITY, CELLULAR; IMMUNOHISTOCHEMISTRY; KILLER CELLS, NATURAL; TUMOR CELLS, CULTURED;

EID: 0031132876     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Welch, W. J. 1992. Mammalian stress response: cell physiology, structure/function of stress proteins, and implications for medicine and disease. Physiol. Rev. 72:1063.
2. Craig, E. A., B. D. Gambill, and R. J. Nelson. 1993. Heat shock proteins: molecular chaperones of protein biogenesis. Microbiol. Rev. 57:402.
3. Welch, W. J., and J. R. Feramisco. 1984. Nuclear and nucleolar localization of the 72,000-dalton heat shock protein in heat-shocked mammalian cells. J. Biol. Chem. 259:4501.
4. Ferrarini, M., S. Heltai, M. R. Zocchi, and C. Rugarli. 1992. Unusual expression and localization of heat-shock proteins in human tumor cells. Int. J. Cancer 51:613.
5. Multhoff, G., C. Botzler, M. Wiesnet, E. Müller, T. Meier, W. Wilmanns, and R. D. Issels. 1995. A stress-inducible 72 kDa heat-shock protein (HSP72) is expressed on the surface of human tumor cells, but not on normal cells. Int. J. Cancer 61:272.
6. Lamb, J. R., V. Bal, J. B. Rothbard, A. Mehlert, P. Mendez-Samperio, and D. B. Young. 1989. The mycobacterial GroEL stress protein: a common target of T-cell recognition in infection and autoimmunity. J. Autoimmun. 2(Suppl.):93.
7. Heufelder, A. E., B. E. Wenzel, and R. S. Bahn. 1992. Cell surface localization of a 72 kilodalton heat shock protein in retroocular fibroblasts from patients with Graves' ophthalmopathy. J. Clin. Endocrinol. Metab. 74:732.
8. Jacquier-Sarlin, M. R., K. Fuller, A. T. Dinh-Xuan, M. J. Richard, and B. S. Polla. 1994. Protective effects of hsp70 in inflammation. Experientia 50:1031.
9. Polla, B. S., S. Kantengwa, G. J. Gleich, M. Kondo, C. M. Reimert, and A. F. Junod. 1993. Spontaneous heat shock protein synthesis by alveolar macrophages in interstitial lung disease associated with phagocytosis of eosinophils. Eur. Respir. J. 6:483.
10. Ullrich, S. J., E. A. Robinson, L. W. Law, M. Willingham, and E. Appella. 1986. A mouse tumor-specific transplantation antigen is a heat shock-related protein. Proc. Natl. Acad. Sci. USA 83:3121.
11. Menoret, A., Y. Patry, C. Burg, and J. Le-Pendu. 1995. Co-segregation of tumor immunogenicity with expression of inducible but not constitutive hsp70 in rat colon carcinomas. J. Immunol. 155:740.
12. Srivastava, P. K., and M. R. Das. 1984. The serologically unique cell surface antigen of Zajdela ascitic hepatoma is also its tumor-associated transplantation antigen. Int. J. Cancer 33:417.
13. Blachere, N. E., H. Udono, S. Janetzki, Z. Li, M. Heike, and P. K. Srivastava. 1993. Heat shock protein vaccines against cancer. J. Immunother. 14:352.
14. + T cells in vivo. Proc. Natl. Acad. Sci. USA 91:3077.
15. Udono, H., and P. K. Srivastava. 1994. Comparison of tumor-specific immunogenicities of stress-induced proteins gp96, hsp90. and hsp70. J. Immunol. 152: 5398.
16. Suto, R., and P. K. Srivastava. 1995. A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides. Science 269:1585.
17. Srivastava, P. K. 1994. Heat shock proteins in immune response to cancer: the Fourth Paradigm. Experientia 50:1054.
18. Vigh, L., D. A. Los, I. Horvath, and N. Murata. 1993. The primary signal in the biological perception of temperature: Pd-catalyzed hydrogenation of membrane lipids stimulated the expression of the desA gene in Synechocystis PCC6803. Proc. Natl. Acad. Sci. USA 90:9090.
19. Fujii, G., S. Horvath, S. Woodward, F. Eiserling, and D. Eisenberg. 1992. A molecular model for membrane fusion based on solution studies of an amphiphilic peptide from HIV gp41. Protein Sci. 1:1454.
20. Vujanovic, N. L., H. Rabinovich, Y. J. Lee, R. B. Herberman, and T. L. Whiteside. 1993. Distinct phenotypic and functional characteristics of human natural killer cells obtained by rapid interleukin 2-induced adherence to plastic. Cell. Immunol. 151:133.
21. Multhoff, G., C. Botzler, M. Wiesnet, G. Eissner, and R. Issels. 1995. CD3-large granular lymphocytes recognize a heat-inducible immunogenic determinant associated with the 72 kDa heat shock protein on human sarcoma cells. Blood 86:1374.
22. Kung, P., G. Goldstein, E. L. Reinherz, and S. F. Schlossman. 1979. Monoclonal antibodies defining distinctive human T cell surface antigens. Science 206:347.
23. Nicoletti, I., Migliorati, G., Pagliacci, M. C., Grignani, F., and Riccardi, C. 1991. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide and flow cytometry. J. Immunol. Methods 139:271.
24. Danscher, G. 1981. Localization of gold in biological tissue: a photochemical method for light and electronmicroscopy. Histochemistry 71:81.
25. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680.
26. Towbin, H., T. Staehelin, and J. Gordon. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76:4350.
27. MacDonald, H. R., H. D. Engers, J. C. Cerottini, and K. T. Brunner. 1974. Generation of cytotoxic T lymphocytes in vitro. J. Exp. Med. 140:718.
28. Parham, P., M. J. Androlewicz, F. M. Brodsky, N. J. Holmes, and J. P. Ways. 1982. Monoclonal antibodies: purification, fragmentation and application to structural and functional studies of class I MHC antigens. J. Immunol. Methods 53:133.
29. Winfield, J. B. 1989. Stress proteins, arthritis and autoimmunity. Arthritis Rheum. 31:1221.
30. Weiss, R. A., M. P. Madaio, J. E. Tomaszewski, and C. J. Kelly. 1994. T cells reactive to an inducible heat shock protein induce disease in toxin-induced interstitial nephritis. J. Exp. Med. 180:2239.
31. de-Graeff-Meeder, E. R., W. van-Eden, G. T. Rijkers, B. J. Prakken, B. J. Zegers, and W. Kuis. 1993. Heat-shock proteins and juvenile chronic arthritis. Clin. Exp. Rheumatol. 11(Suppl. 9):S25.
32. Chopp, M. 1993. The roles of heat shock proteins and immediate early genes in central nervous system normal function and pathology. Curr. Opin. Neurol. Neurosurg. 6:6.
33. Moliterno, R., L. Valdivia, F. Pan, and R. J. Duquesnoy. 1995. Heat shock protein reactivity of lymphocytes isolated from heterotopic rat cardiac allografts. Transplantation 59:598.
34. Poccia, F., P. Piselli, S. Di-Cesare, S. Bach, V. Colizzi, M. Mattei, A. Bolognesi, and F. Stirpe. 1992. Recognition and killing of tumour cells expressing heat shock protein 65 kDa with immunotoxins containing saporin. Br. J. Cancer 66: 427.
35. Di-Cesare, S., F. Poccia, A. Mastino, and V. Colizzi. 1992. Surface expressed heat-shock proteins by stressed or human immunodeficiency virus (HIV)-infected lymphoid cells represent the target for antibody-dependent cellular cytotoxicity. Immunology 76:341.
36. Polla, B. S. 1991. Heat shock proteins in host-parasite interactions. Immunol. Today 12:38.
37. Shinnick, T. M. 1991. Heat shock proteins as antigens of bacterial and parasitic pathogens. Curr. Top. Microbiol. Immunol. 167:145.
38. Engman, D. M., E. A. Dragon, and J. E. Donelson. 1990. Human humoral immunity to hsp70 during Trypanosoma cruzi infection. J. Immunol. 144:3987.
39. Ferrarini, M., S. M. Pupa, M. R. Zocchi, C. Rgarli, and S. Menard. 1994. Distribution of HSP72 and monomeric laminin receptor expression in human liung cancers infiltrated hy gamma delta T lymphocytes. Int. J. Cancer 57:486.
40. Tamura, Y., N. Tsuboi, N. Sato, and K. Kikuchi. 1993. 70 kDa heat shock cognate protein is a transformation-associated antigen and a possible target for the host's anti-tumor immunity. J. Immunol. 151:5516.
41. Tsuboi, N., M. Ishikawa, Y. Tamura, S. Takayama, H. Tobioka, A. Matsuura, K. Hirayoshi, K. Nagata, N. Sato, and K. Kikuchi. 1994. Monoclonal antibody specifically reacting against 73-kilodalton heat shock cognate protein: possible expression on mammalian cell surface. Hybridoma 13:373.
42. Multhoff, G., and L. Hightower. 1996. Cell surface expression of heat shock proteins and the immune response. Cell Stress Chaperones 1:167.
43. Chouchane, L., S. Bowers, S. Sawasdikosol, R. M. Simpson, and T. J. Kindt. 1994. Heat shock proteins expressed on the surface of human T cell leukemia virus type I-infected cell lines induce autoantibodies in rabbits. J. Infect. Dis. 169:253.
44. Mignatti, P., T. Morimoto, and D. B. Rifkin. 1992. Basic fibroblast growth factor, a protein devoid of secretory signal sequence, is released by cells via a pathway independent of the endoplasmatic reticulum-Golgi complex. J. Cell. Physiol. 151: 81.
45. Rubartelli, A., F. Cozzolino, M. Talio, and R. Sitia. 1990. A novel secretory pathway for interleukin-1β, a protein lacking a signal sequence. EMBO J. 9:1503.
46. Terleckey, S. R. 1994. HSP70s and lysosomal proteolysis. Experientia 50:1021.
47. Hang, H., and M. H. Fox. 1995. Expression of hsp70 induced in CHO cells by 45.0 degrees C hyperthermia is cell cycle associated and DNA synthesis dependent. Cytometry 19:119.
48. Milarski, K. L., W. J. Welch, and R. I. Morimoto. 1989. Cell cycle-dependent association of HSP70 with specific cellular proteins. J. Cell Biol. 108:413.
49. Gomez, F. J., A. M. Gomez, and G. S. J. Deepe. 1992. An 80-kilodalton antigen from Histoplasma capsulatum that has homology to heat shock protein 70 induces cell-mediated immune responses and protection in mice. Infect. Immun. 60:2565.
50. Botzler, C., H. J. Kolb, R. D. Issels, and G. Multhoff. 1996. Noncytotoxic alkyl-lysophospholipid treatment increases sensitivity of leukemic K562 cells to lysis by natural killer (NK) cells. Int. J. Cancer 65:633.
51. Moretta, L., E. Ciccone, A. Poggi, M. C. Mingari, and A. Moretta. 1994. Ontogeny, specific functions and receptors of human natural killer cells. Immunol. Lett. 40:83.
52. Zamai, L., G. Zauli, A. Bavelloni, S. Marmiroli, A. Cataldi, G. Weber, and M. Vitale. 1995. Tiazofurin induces a down-modulation of ICAM-1 expression on K562 target cells impairing NK adhesion and killing. Cell. Immunol. 164:100.
53. Quillet-Mary, A., L. Cavarec, N. Kermarrec, C. Marchiol-Fournigault, M. L. Gil, H. Conjeaud, and D. Fradelizi. 1991. Target lysis hy human LAK cells is critically dependent upon target binding properties, but LFA-1, LFA-3 and ICAM-1 are not the major adhesion ligands on targets. Int. J. Cancer 47:473.
54. Akella, R., and R. E. Hall. 1992. Expression of the adhesion molecules ICAM-1 and ICAM-2 on tumor cell lines does not correlate with their susceptibility to natural killer cell-mediated cytolysis: evidence for additional ligands for effector cell beta integrins. Eur. J. Immunol. 22:1069.
55. Vitale, M., S. Sivori, D. Pende, L. Moretta, and A. Moretta. 1995. Coexpression of two functionally independent p58 inhibitory receptors in human natural killer cell clones results in the inability to kill all normal allogeneic target cells. Proc. Natl. Accad. Sci. USA 92:3536.
56. Brennan, J., F. Takei, S. Wong, and D. L. Mager. 1995. Carbohydrate recognition by a natural killer cell receptor, Ly-49C. J. Biol. Chem. 270:9691.