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Volumn 32, Issue 5, 2009, Pages 359-378

Safety profile of the respiratory fluoroquinolone moxifloxacin: Comparison with other fluoroquinolones and other antibacterial classes

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPENICILLIN; AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; AZITHROMYCIN; CEFALEXIN; CEFIXIME; CEFUROXIME AXETIL; CEPHALOSPORIN; CIPROFLOXACIN; CLARITHROMYCIN; COTRIMOXAZOLE; ERYTHROMYCIN; FLEROXACIN; GATIFLOXACIN; LEVOFLOXACIN; LOMEFLOXACIN; MACROLIDE; MOXIFLOXACIN; NORFLOXACIN; OFLOXACIN; PENICILLIN DERIVATIVE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIFAMPICIN; SULFONAMIDE; TELITHROMYCIN; TETRACYCLINE; TROVAFLOXACIN; UNINDEXED DRUG; VANCOMYCIN;

EID: 65949098180     PISSN: 01145916     EISSN: None     Source Type: Journal    
DOI: 10.2165/00002018-200932050-00001     Document Type: Review
Times cited : (104)

References (170)
  • 1
    • 65949095152 scopus 로고    scopus 로고
    • US Levaquin® package insert [online, Available fromURL:, Accessed 2009 Mar 18
    • US Levaquin® package insert [online]. Available fromURL: http://www.levaquin.com/levaquin/shared/pi/levaquin.pdf [Accessed 2009 Mar 18]
  • 2
    • 65949084390 scopus 로고    scopus 로고
    • US Avelox® package insert [online, Available from URL:, Accessed 2009 Mar 18
    • US Avelox® package insert [online]. Available from URL: http://www.univgraph.com/bayer/inserts/avelox.pdf [Accessed 2009 Mar 18]
  • 3
    • 15944382760 scopus 로고    scopus 로고
    • Van Bambeke F, Michot JM, Van Eldere J. et al. Quinolones in 2005: an update. Clin Microbiol Infect 2005 Apr; 11 (4): 256-80
    • Van Bambeke F, Michot JM, Van Eldere J. et al. Quinolones in 2005: an update. Clin Microbiol Infect 2005 Apr; 11 (4): 256-80
  • 4
    • 33847155159 scopus 로고    scopus 로고
    • Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of communityacquired pneumonia in adults
    • Mar 1;
    • Mandell LA, Wunderink RG, Anzueto A, et al. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of communityacquired pneumonia in adults. Clin Infect Dis 2007 Mar 1; 44 Suppl. 2: S27-72
    • (2007) Clin Infect Dis , vol.44 , Issue.SUPPL. 2
    • Mandell, L.A.1    Wunderink, R.G.2    Anzueto, A.3
  • 5
    • 29244469121 scopus 로고    scopus 로고
    • Guidelines for the management of adult lower respiratory tract infections
    • Dec;
    • Woodhead M, Blasi F, Ewig S, et al. Guidelines for the management of adult lower respiratory tract infections. Eur Respir J 2005 Dec; 26 (6): 1138-80
    • (2005) Eur Respir J , vol.26 , Issue.6 , pp. 1138-1180
    • Woodhead, M.1    Blasi, F.2    Ewig, S.3
  • 6
    • 35948960351 scopus 로고    scopus 로고
    • Van Bambeke F, Reinert RR, Appelbaum PC, et al. Multidrug-resistant Streptococcus pneumoniae infections: current and future therapeutic options.Drugs 2007; 67 (16): 2355-82
    • Van Bambeke F, Reinert RR, Appelbaum PC, et al. Multidrug-resistant Streptococcus pneumoniae infections: current and future therapeutic options.Drugs 2007; 67 (16): 2355-82
  • 7
    • 33846031160 scopus 로고    scopus 로고
    • Molecular characterization of increasing fluoroquinolone resistance in Streptococcus pneumoniae isolates in Canada, 1997 to 2005
    • Jan;
    • Adam HJ, Schurek KN, Nichol KA, et al. Molecular characterization of increasing fluoroquinolone resistance in Streptococcus pneumoniae isolates in Canada, 1997 to 2005. Antimicrob Agents Chemother 2007 Jan; 51 (1): 198-207
    • (2007) Antimicrob Agents Chemother , vol.51 , Issue.1 , pp. 198-207
    • Adam, H.J.1    Schurek, K.N.2    Nichol, K.A.3
  • 8
    • 33748747762 scopus 로고    scopus 로고
    • Evolution of resistance patterns and identification of risk factors for Streptococcus pneumoniae colonisation in daycare centre attendees in Athens, Greece
    • Oct;
    • Volonakis K, Souli M, Kapaskelis A, et al. Evolution of resistance patterns and identification of risk factors for Streptococcus pneumoniae colonisation in daycare centre attendees in Athens, Greece. Int J Antimicrob Agents 2006 Oct; 28 (4): 297-301
    • (2006) Int J Antimicrob Agents , vol.28 , Issue.4 , pp. 297-301
    • Volonakis, K.1    Souli, M.2    Kapaskelis, A.3
  • 9
    • 35148818301 scopus 로고    scopus 로고
    • Population genetics and antibiotic susceptibility of invasive Haemophilus influenzae in Manitoba, Canada, from 2000 to 2006
    • Nov;
    • Sill ML, Law DK, Zhou J, et al. Population genetics and antibiotic susceptibility of invasive Haemophilus influenzae in Manitoba, Canada, from 2000 to 2006. FEMS Immunol Med Microbiol 2007 Nov; 51 (2): 270-6
    • (2007) FEMS Immunol Med Microbiol , vol.51 , Issue.2 , pp. 270-276
    • Sill, M.L.1    Law, D.K.2    Zhou, J.3
  • 10
    • 24044504090 scopus 로고    scopus 로고
    • Susceptibility of European beta-lactamase-positive and -negative Haemophilus influenzae isolates from the periods 1997/1998 and 2002/2003
    • Jul;
    • Fluit AC, Florijn A, Verhoef J, et al. Susceptibility of European beta-lactamase-positive and -negative Haemophilus influenzae isolates from the periods 1997/1998 and 2002/2003. J Antimicrob Chemother 2005 Jul; 56 (1): 133-8
    • (2005) J Antimicrob Chemother , vol.56 , Issue.1 , pp. 133-138
    • Fluit, A.C.1    Florijn, A.2    Verhoef, J.3
  • 11
    • 34447258125 scopus 로고    scopus 로고
    • Prevalence, characteristics, and molecular epidemiology of macrolide and fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae at five tertiary-care hospitals in Korea
    • Jul;
    • Shin JH, Jung HJ, Kim HR, et al. Prevalence, characteristics, and molecular epidemiology of macrolide and fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae at five tertiary-care hospitals in Korea. Antimicrob Agents Chemother 2007 Jul; 51 (7): 2625-7
    • (2007) Antimicrob Agents Chemother , vol.51 , Issue.7 , pp. 2625-2627
    • Shin, J.H.1    Jung, H.J.2    Kim, H.R.3
  • 12
    • 33747623423 scopus 로고    scopus 로고
    • Emergence of multidrug-resistant Streptococcus pneumoniae: Report from the SENTRY Antimicrobial Surveillance Program (1999-2003)
    • Sep;
    • Johnson DM, Stilwell MG, Fritsche TR, et al. Emergence of multidrug-resistant Streptococcus pneumoniae: report from the SENTRY Antimicrobial Surveillance Program (1999-2003). Diagn Microbiol Infect Dis 2006 Sep; 56 (1): 69-74
    • (2006) Diagn Microbiol Infect Dis , vol.56 , Issue.1 , pp. 69-74
    • Johnson, D.M.1    Stilwell, M.G.2    Fritsche, T.R.3
  • 13
    • 27144498544 scopus 로고    scopus 로고
    • Are fluoroquinolone-susceptible isolates of Streptococcus pneumoniae really susceptible? A comparison of resistance mechanisms in Canadian isolates from 1997 and 2003
    • Oct;
    • Schurek KN, Adam HJ, Siemens CG, et al. Are fluoroquinolone-susceptible isolates of Streptococcus pneumoniae really susceptible? A comparison of resistance mechanisms in Canadian isolates from 1997 and 2003. J Antimicrob Chemother 2005 Oct; 56 (4): 769-72
    • (2005) J Antimicrob Chemother , vol.56 , Issue.4 , pp. 769-772
    • Schurek, K.N.1    Adam, H.J.2    Siemens, C.G.3
  • 14
    • 7044233601 scopus 로고    scopus 로고
    • Pharmacodynamic target attainment analysis against Streptococcus pneumoniae using levofloxacin 500 mg, 750 mg and 1000mg once daily in plasma (P) and epithelial lining fluid (ELF) of hospitalized patients with community acquired pneumonia (CAP)
    • Nov;
    • Noreddin AM, Marras TK, Sanders K, et al. Pharmacodynamic target attainment analysis against Streptococcus pneumoniae using levofloxacin 500 mg, 750 mg and 1000mg once daily in plasma (P) and epithelial lining fluid (ELF) of hospitalized patients with community acquired pneumonia (CAP). Int J Antimicrob Agents 2004 Nov; 24 (5): 479-84
    • (2004) Int J Antimicrob Agents , vol.24 , Issue.5 , pp. 479-484
    • Noreddin, A.M.1    Marras, T.K.2    Sanders, K.3
  • 15
    • 33746317016 scopus 로고    scopus 로고
    • Intrapulmonary pharmacokinetics and pharmacodynamics of high-dose levofloxacin in healthy volunteer subjects
    • Aug;
    • Conte Jr JE, Golden JA, McIver M, et al. Intrapulmonary pharmacokinetics and pharmacodynamics of high-dose levofloxacin in healthy volunteer subjects. Int J Antimicrob Agents 2006 Aug; 28 (2): 114-21
    • (2006) Int J Antimicrob Agents , vol.28 , Issue.2 , pp. 114-121
    • Conte Jr, J.E.1    Golden, J.A.2    McIver, M.3
  • 16
    • 21144433018 scopus 로고    scopus 로고
    • New fluoroquinolones in lower respiratory tract infections and emerging patterns of pneumococcal resistance
    • Jun;
    • Ferrara AM. New fluoroquinolones in lower respiratory tract infections and emerging patterns of pneumococcal resistance. Infection 2005 Jun; 33 (3): 106-14
    • (2005) Infection , vol.33 , Issue.3 , pp. 106-114
    • Ferrara, A.M.1
  • 17
    • 18644375970 scopus 로고    scopus 로고
    • Guide to selection of fluoroquinolones in patients with lower respiratory tract infections
    • Shams WE, Evans ME. Guide to selection of fluoroquinolones in patients with lower respiratory tract infections. Drugs 2005; 65 (7): 949-91
    • (2005) Drugs , vol.65 , Issue.7 , pp. 949-991
    • Shams, W.E.1    Evans, M.E.2
  • 18
    • 14544287733 scopus 로고    scopus 로고
    • Moxifloxacin in respiratory tract infections
    • Feb;
    • Miravitlles M. Moxifloxacin in respiratory tract infections. Expert Opin Pharmacother 2005 Feb; 6 (2): 283-93
    • (2005) Expert Opin Pharmacother , vol.6 , Issue.2 , pp. 283-293
    • Miravitlles, M.1
  • 19
    • 4344674987 scopus 로고    scopus 로고
    • Safety profile of oral and intravenous moxifloxacin: Cumulative data from clinical trials and postmarketing studies
    • Jul;
    • Ball P, Stahlmann R, Kubin R, et al. Safety profile of oral and intravenous moxifloxacin: cumulative data from clinical trials and postmarketing studies. Clin Ther 2004 Jul; 26 (7): 940-50
    • (2004) Clin Ther , vol.26 , Issue.7 , pp. 940-950
    • Ball, P.1    Stahlmann, R.2    Kubin, R.3
  • 20
    • 19544392516 scopus 로고    scopus 로고
    • Retrospective analysis of the safety profile of oral moxifloxacin in elderly patients enrolled in clinical trials
    • Andriole VT, Haverstock DC, Choudhri SH. Retrospective analysis of the safety profile of oral moxifloxacin in elderly patients enrolled in clinical trials. Drug Saf 2005; 28 (5): 443-52
    • (2005) Drug Saf , vol.28 , Issue.5 , pp. 443-452
    • Andriole, V.T.1    Haverstock, D.C.2    Choudhri, S.H.3
  • 21
    • 0034061875 scopus 로고    scopus 로고
    • Balfour JA, Lamb HM. Moxifloxacin: a review of its clinical potential in the management of community-acquired respiratory tract infections.Drugs 2000 Jan; 59 (1): 115-39
    • Balfour JA, Lamb HM. Moxifloxacin: a review of its clinical potential in the management of community-acquired respiratory tract infections.Drugs 2000 Jan; 59 (1): 115-39
  • 22
    • 4344651170 scopus 로고    scopus 로고
    • Efficacy and tolerability of moxifloxacin in patients with sinusitis treated in general practice: Results of a post-marketing surveillance study
    • Elies W, Landen H, Stauch K. Efficacy and tolerability of moxifloxacin in patients with sinusitis treated in general practice: results of a post-marketing surveillance study. Clin Drug Investig 2004; 24 (8): 431-9
    • (2004) Clin Drug Investig , vol.24 , Issue.8 , pp. 431-439
    • Elies, W.1    Landen, H.2    Stauch, K.3
  • 23
    • 41649104639 scopus 로고    scopus 로고
    • Fluoroquinolones compared with beta-lactam antibiotics for the treatment of acute bacterial sinusitis: A meta-analysis of randomized controlled trials
    • Mar 25;
    • Karageorgopoulos DE, Giannopoulou KP, Grammatikos AP, et al. Fluoroquinolones compared with beta-lactam antibiotics for the treatment of acute bacterial sinusitis: a meta-analysis of randomized controlled trials. CMAJ 2008 Mar 25; 178 (7): 845-54
    • (2008) CMAJ , vol.178 , Issue.7 , pp. 845-854
    • Karageorgopoulos, D.E.1    Giannopoulou, K.P.2    Grammatikos, A.P.3
  • 24
    • 33847759477 scopus 로고    scopus 로고
    • Moxifloxacin versus amoxicillin/clavulanate in the treatment of acute sinusitis
    • Mar;
    • Arrieta JR, Galgano AS, Sakano E, et al. Moxifloxacin versus amoxicillin/clavulanate in the treatment of acute sinusitis. Am J Otolaryngol 2007 Mar; 28 (2): 78-82
    • (2007) Am J Otolaryngol , vol.28 , Issue.2 , pp. 78-82
    • Arrieta, J.R.1    Galgano, A.S.2    Sakano, E.3
  • 25
    • 33747392552 scopus 로고    scopus 로고
    • Efficacy and tolerability of moxifloxacin in patients with respiratory tract infections treated in general practice: Results of a post-marketing surveillance study
    • Chen W, Wu C, Li Z, et al. Efficacy and tolerability of moxifloxacin in patients with respiratory tract infections treated in general practice: results of a post-marketing surveillance study. Clin Drug Investig 2006; 26 (9): 501-9
    • (2006) Clin Drug Investig , vol.26 , Issue.9 , pp. 501-509
    • Chen, W.1    Wu, C.2    Li, Z.3
  • 26
    • 0036760802 scopus 로고    scopus 로고
    • Oral fluoroquinolones in the treatment of pneumonia, bronchitis and sinusitis
    • Sep;
    • Mittmann N, Jivarj F, Wong A, et al. Oral fluoroquinolones in the treatment of pneumonia, bronchitis and sinusitis. Can J Infect Dis 2002 Sep; 13 (5): 293-300
    • (2002) Can J Infect Dis , vol.13 , Issue.5 , pp. 293-300
    • Mittmann, N.1    Jivarj, F.2    Wong, A.3
  • 27
    • 1942534978 scopus 로고    scopus 로고
    • Clinical experience with moxifloxacin in patients with respiratory tract infections
    • May;
    • Faich GA, Morganroth J, Whitehouse AB, et al. Clinical experience with moxifloxacin in patients with respiratory tract infections. Ann Pharmacother 2004 May; 38 (5): 749-54
    • (2004) Ann Pharmacother , vol.38 , Issue.5 , pp. 749-754
    • Faich, G.A.1    Morganroth, J.2    Whitehouse, A.B.3
  • 28
    • 0037232760 scopus 로고    scopus 로고
    • Comparison of the efficacy and safety of moxifloxacin and trovafloxacin for the treatment of acute, bacterial maxillary sinusitis in adults
    • Jan;
    • Klossek JM, Siegert R, Nikolaidis P, et al. Comparison of the efficacy and safety of moxifloxacin and trovafloxacin for the treatment of acute, bacterial maxillary sinusitis in adults. J Laryngol Otol 2003 Jan; 117 (1): 43-51
    • (2003) J Laryngol Otol , vol.117 , Issue.1 , pp. 43-51
    • Klossek, J.M.1    Siegert, R.2    Nikolaidis, P.3
  • 29
    • 4444243654 scopus 로고    scopus 로고
    • Efficacy and safety of oral telithromycin once daily for 5 days versus moxifloxacin once daily for 10 days in the treatment of acute bacterial rhinosinusitis
    • Sep;
    • Ferguson BJ, Guzzetta RV, Spector SL, et al. Efficacy and safety of oral telithromycin once daily for 5 days versus moxifloxacin once daily for 10 days in the treatment of acute bacterial rhinosinusitis. Otolaryngol Head Neck Surg 2004 Sep; 131 (3): 207-14
    • (2004) Otolaryngol Head Neck Surg , vol.131 , Issue.3 , pp. 207-214
    • Ferguson, B.J.1    Guzzetta, R.V.2    Spector, S.L.3
  • 30
    • 4344674592 scopus 로고    scopus 로고
    • Daily-practice treatment of acute exacerbations of chronic bronchitis with moxifloxacin in a large cohort in Germany
    • Koch H, Landen H, Stauch K. Daily-practice treatment of acute exacerbations of chronic bronchitis with moxifloxacin in a large cohort in Germany. Clin Drug Investig 2004; 24 (8): 449-55
    • (2004) Clin Drug Investig , vol.24 , Issue.8 , pp. 449-455
    • Koch, H.1    Landen, H.2    Stauch, K.3
  • 31
    • 33845442817 scopus 로고    scopus 로고
    • Real-life treatment of acute exacerbations of chronic bronchitis with moxifloxacin or macrolides: A comparative post-marketing surveillance study in general practice
    • Schaberg T, Moller M, File T, et al. Real-life treatment of acute exacerbations of chronic bronchitis with moxifloxacin or macrolides: a comparative post-marketing surveillance study in general practice. Clin Drug Investig 2006; 26 (12): 733-44
    • (2006) Clin Drug Investig , vol.26 , Issue.12 , pp. 733-744
    • Schaberg, T.1    Moller, M.2    File, T.3
  • 32
    • 33845652998 scopus 로고    scopus 로고
    • Efficacy and safety of 3-day azithromycin versus 5-day moxifloxacin for the treatment of acute bacterial exacerbations of chronic bronchitis
    • Jan;
    • Zervos M, Martinez FJ, Amsden GW, et al. Efficacy and safety of 3-day azithromycin versus 5-day moxifloxacin for the treatment of acute bacterial exacerbations of chronic bronchitis. Int J Antimicrob Agents 2007 Jan; 29 (1): 56-61
    • (2007) Int J Antimicrob Agents , vol.29 , Issue.1 , pp. 56-61
    • Zervos, M.1    Martinez, F.J.2    Amsden, G.W.3
  • 33
    • 33746211627 scopus 로고    scopus 로고
    • Moxifloxacin versus levofloxacin against acute exacerbations of chronic bronchitis: The Latin American Cohort
    • Sep;
    • Urueta-Robledo J, Ariza H, Jardim JR, et al. Moxifloxacin versus levofloxacin against acute exacerbations of chronic bronchitis: the Latin American Cohort. Respir Med 2006 Sep; 100 (9): 1504-11
    • (2006) Respir Med , vol.100 , Issue.9 , pp. 1504-1511
    • Urueta-Robledo, J.1    Ariza, H.2    Jardim, J.R.3
  • 34
    • 0842263832 scopus 로고    scopus 로고
    • Five-day moxifloxacin therapy compared with 7-day co-amoxiclav therapy for the treatment of acute exacerbation of chronic bronchitis
    • Feb;
    • Starakis I, Gogos CA, Bassaris H. Five-day moxifloxacin therapy compared with 7-day co-amoxiclav therapy for the treatment of acute exacerbation of chronic bronchitis. Int J Antimicrob Agents 2004 Feb; 23 (2): 129-37
    • (2004) Int J Antimicrob Agents , vol.23 , Issue.2 , pp. 129-137
    • Starakis, I.1    Gogos, C.A.2    Bassaris, H.3
  • 35
    • 0036972498 scopus 로고    scopus 로고
    • Efficacy and safety of short course (5-day) moxifloxacin versus 7-day ceftriaxone in the treatment of acute exacerbations of chronic bronchitis (AECB)
    • Dec;
    • Grassi C, Casali L, Curti E, et al. Efficacy and safety of short course (5-day) moxifloxacin versus 7-day ceftriaxone in the treatment of acute exacerbations of chronic bronchitis (AECB). J Chemother 2002 Dec; 14 (6): 597-608
    • (2002) J Chemother , vol.14 , Issue.6 , pp. 597-608
    • Grassi, C.1    Casali, L.2    Curti, E.3
  • 36
    • 0034811145 scopus 로고    scopus 로고
    • A multinational, multicentre, non-blinded, randomized study of moxifloxacin oral tablets compared with co-amoxiclav oral tablets in the treatment of acute exacerbation of chronic bronchitis
    • Jul;
    • Schaberg T, Ballin I, Huchon G, et al. A multinational, multicentre, non-blinded, randomized study of moxifloxacin oral tablets compared with co-amoxiclav oral tablets in the treatment of acute exacerbation of chronic bronchitis. J Int Med Res 2001 Jul; 29 (4): 314-28
    • (2001) J Int Med Res , vol.29 , Issue.4 , pp. 314-328
    • Schaberg, T.1    Ballin, I.2    Huchon, G.3
  • 37
    • 0035017628 scopus 로고    scopus 로고
    • Treatment outcomes in acute exacerbations of chronic bronchitis: Comparison of macrolides and moxifloxacin from the patient perspective
    • Mar;
    • Lorenz J, Thate-Waschke IM, Mast O, et al. Treatment outcomes in acute exacerbations of chronic bronchitis: comparison of macrolides and moxifloxacin from the patient perspective. J Int Med Res 2001 Mar; 29 (2): 74-86
    • (2001) J Int Med Res , vol.29 , Issue.2 , pp. 74-86
    • Lorenz, J.1    Thate-Waschke, I.M.2    Mast, O.3
  • 38
    • 27644592464 scopus 로고    scopus 로고
    • Efficacy and tolerability of sequential intravenous/oral moxifloxacin therapy in pneumonia: Results of the first post-marketing surveillance study with intravenous moxifloxacin in hospital practice
    • Barth J, Stauch K, Landen H. Efficacy and tolerability of sequential intravenous/oral moxifloxacin therapy in pneumonia: results of the first post-marketing surveillance study with intravenous moxifloxacin in hospital practice. Clin Drug Investig 2005; 25 (11): 691-700
    • (2005) Clin Drug Investig , vol.25 , Issue.11 , pp. 691-700
    • Barth, J.1    Stauch, K.2    Landen, H.3
  • 39
    • 4344565726 scopus 로고    scopus 로고
    • Once-daily moxifloxacin therapy for community-acquired pneumonia in general practice: Evidence from a post-marketing surveillance study of 1467 patients
    • Koch H, Landen H, Stauch K. Once-daily moxifloxacin therapy for community-acquired pneumonia in general practice: evidence from a post-marketing surveillance study of 1467 patients. Clin Drug Investig 2004; 24 (8): 441-8
    • (2004) Clin Drug Investig , vol.24 , Issue.8 , pp. 441-448
    • Koch, H.1    Landen, H.2    Stauch, K.3
  • 40
    • 29244479536 scopus 로고    scopus 로고
    • Community-Acquired Pneumonia Recovery in the Elderly (CAPRIE): Efficacy and safety of moxifloxacin therapy versus that of levofloxacin therapy
    • Jan 1;
    • Anzueto A, Niederman MS, Pearle J, et al. Community-Acquired Pneumonia Recovery in the Elderly (CAPRIE): efficacy and safety of moxifloxacin therapy versus that of levofloxacin therapy. Clin Infect Dis 2006 Jan 1; 42 (1): 73-81
    • (2006) Clin Infect Dis , vol.42 , Issue.1 , pp. 73-81
    • Anzueto, A.1    Niederman, M.S.2    Pearle, J.3
  • 41
    • 28144464151 scopus 로고    scopus 로고
    • A randomized trial comparing the cardiac rhythm safety of moxifloxacin versus levofloxacin in elderly patients hospitalized with community-acquired pneumonia
    • Nov;
    • Morganroth J, Dimarco JP, Anzueto A, et al. A randomized trial comparing the cardiac rhythm safety of moxifloxacin versus levofloxacin in elderly patients hospitalized with community-acquired pneumonia. Chest 2005 Nov; 128 (5): 3398-406
    • (2005) Chest , vol.128 , Issue.5 , pp. 3398-3406
    • Morganroth, J.1    Dimarco, J.P.2    Anzueto, A.3
  • 42
    • 38449117617 scopus 로고    scopus 로고
    • Vyas H, Krishnaswamy G. Images in clinical medicine: quinolone-associated rupture of the Achilles' tendon. N Engl J Med 2007 Nov 15; 357 (20): 2067
    • Vyas H, Krishnaswamy G. Images in clinical medicine: quinolone-associated rupture of the Achilles' tendon. N Engl J Med 2007 Nov 15; 357 (20): 2067
  • 43
    • 8744257509 scopus 로고    scopus 로고
    • Efficacy and safety of sequential moxifloxacin for treatment of communityacquired pneumonia associated with atypical pathogens
    • Oct;
    • Hoeffken G, Talan D, Larsen LS, et al. Efficacy and safety of sequential moxifloxacin for treatment of communityacquired pneumonia associated with atypical pathogens. Eur J Clin Microbiol Infect Dis 2004 Oct; 23 (10): 772-5
    • (2004) Eur J Clin Microbiol Infect Dis , vol.23 , Issue.10 , pp. 772-775
    • Hoeffken, G.1    Talan, D.2    Larsen, L.S.3
  • 44
    • 6344243659 scopus 로고    scopus 로고
    • Safety and efficacy of sequential i.v. to p.o. moxifloxacin versus conventional combination therapies for the treatment of communityacquired pneumonia in patients requiring initial i.v. therapy
    • Nov;
    • Katz E, Larsen LS, Fogarty CM, et al. Safety and efficacy of sequential i.v. to p.o. moxifloxacin versus conventional combination therapies for the treatment of communityacquired pneumonia in patients requiring initial i.v. therapy. J Emerg Med 2004 Nov; 27 (4): 395-405
    • (2004) J Emerg Med , vol.27 , Issue.4 , pp. 395-405
    • Katz, E.1    Larsen, L.S.2    Fogarty, C.M.3
  • 45
    • 21644455261 scopus 로고    scopus 로고
    • Moxifloxacin monotherapy compared to amoxicillin-clavulanate plus roxithromycin for nonsevere community-acquired pneumonia in adults with risk factors
    • Jun;
    • Portier H, Brambilla C, Garre M, et al. Moxifloxacin monotherapy compared to amoxicillin-clavulanate plus roxithromycin for nonsevere community-acquired pneumonia in adults with risk factors. Eur J Clin Microbiol Infect Dis 2005 Jun; 24 (6): 367-76
    • (2005) Eur J Clin Microbiol Infect Dis , vol.24 , Issue.6 , pp. 367-376
    • Portier, H.1    Brambilla, C.2    Garre, M.3
  • 46
    • 0036096232 scopus 로고    scopus 로고
    • Randomized controlled trial of sequential intravenous (i.v.) and oral moxifloxacin compared with sequential i.v. and oral coamoxiclav with or without clarithromycin in patients with community-acquired pneumonia requiring initial parenteral treatment
    • Jun;
    • Finch R, Schurmann D, Collins O, et al. Randomized controlled trial of sequential intravenous (i.v.) and oral moxifloxacin compared with sequential i.v. and oral coamoxiclav with or without clarithromycin in patients with community-acquired pneumonia requiring initial parenteral treatment. Antimicrob Agents Chemother 2002 Jun; 46 (6): 1746-54
    • (2002) Antimicrob Agents Chemother , vol.46 , Issue.6 , pp. 1746-1754
    • Finch, R.1    Schurmann, D.2    Collins, O.3
  • 47
    • 0037249385 scopus 로고    scopus 로고
    • Effectiveness of oral moxifloxacin in standard first-line therapy in communityacquired pneumonia
    • Jan;
    • Torres A, Muir JF, Corris P, et al. Effectiveness of oral moxifloxacin in standard first-line therapy in communityacquired pneumonia. Eur Respir J 2003 Jan; 21 (1): 135-43
    • (2003) Eur Respir J , vol.21 , Issue.1 , pp. 135-143
    • Torres, A.1    Muir, J.F.2    Corris, P.3
  • 48
    • 0034933394 scopus 로고    scopus 로고
    • The efficacy and safety of two oral moxifloxacin regimens compared to oral clarithromycin in the treatment of communityacquired pneumonia
    • Jul;
    • Hoeffken G, Meyer HP, Winter J, et al. The efficacy and safety of two oral moxifloxacin regimens compared to oral clarithromycin in the treatment of communityacquired pneumonia. Respir Med 2001 Jul; 95 (7): 553-64
    • (2001) Respir Med , vol.95 , Issue.7 , pp. 553-564
    • Hoeffken, G.1    Meyer, H.P.2    Winter, J.3
  • 49
    • 37449018639 scopus 로고    scopus 로고
    • A randomized study of sequential intravenous/oral moxifloxacin in comparison to sequential intravenous ceftriaxone/oral cefuroxime axetil in patients with hospital-acquired pneumonia
    • Dec;
    • Hoffken G, Barth J, Rubinstein E, et al. A randomized study of sequential intravenous/oral moxifloxacin in comparison to sequential intravenous ceftriaxone/oral cefuroxime axetil in patients with hospital-acquired pneumonia. Infection 2007 Dec; 35 (6): 414-20
    • (2007) Infection , vol.35 , Issue.6 , pp. 414-420
    • Hoffken, G.1    Barth, J.2    Rubinstein, E.3
  • 50
    • 0037272414 scopus 로고    scopus 로고
    • Adverse drug reactions related to the use of fluoroquinolone antimicrobials: An analysis of spontaneous reports and fluoroquinolone consumption data from three italian regions
    • Leone R, Venegoni M, Motola D, et al. Adverse drug reactions related to the use of fluoroquinolone antimicrobials: an analysis of spontaneous reports and fluoroquinolone consumption data from three italian regions. Drug Saf 2003; 26 (2): 109-20
    • (2003) Drug Saf , vol.26 , Issue.2 , pp. 109-120
    • Leone, R.1    Venegoni, M.2    Motola, D.3
  • 51
    • 0041653426 scopus 로고    scopus 로고
    • Van der Linden PD, Sturkenboom MC, Herings RM, et al. Increased risk of achilles tendon rupture with quinolone antibacterial use, especially in elderly patients taking oral corticosteroids. Arch Intern Med 2003 Aug 11; 163 (15): 1801-7
    • Van der Linden PD, Sturkenboom MC, Herings RM, et al. Increased risk of achilles tendon rupture with quinolone antibacterial use, especially in elderly patients taking oral corticosteroids. Arch Intern Med 2003 Aug 11; 163 (15): 1801-7
  • 52
    • 0028880443 scopus 로고
    • Medication use and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis
    • Dec 14;
    • Roujeau JC, Kelly JP, Naldi L, et al. Medication use and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis. N Engl J Med 1995 Dec 14; 333 (24): 1600-7
    • (1995) N Engl J Med , vol.333 , Issue.24 , pp. 1600-1607
    • Roujeau, J.C.1    Kelly, J.P.2    Naldi, L.3
  • 53
    • 33645399023 scopus 로고    scopus 로고
    • Outpatient gatifloxacin therapy and dysglycemia in older adults
    • Mar 30;
    • Park-Wyllie LY, Juurlink DN, Kopp A, et al. Outpatient gatifloxacin therapy and dysglycemia in older adults. N Engl J Med 2006 Mar 30; 354 (13): 1352-61
    • (2006) N Engl J Med , vol.354 , Issue.13 , pp. 1352-1361
    • Park-Wyllie, L.Y.1    Juurlink, D.N.2    Kopp, A.3
  • 54
    • 33845909019 scopus 로고    scopus 로고
    • Hepatic adverse drug reactions: A case/non-case study in Italy
    • Jan;
    • Motola D, Vargiu A, Leone R, et al. Hepatic adverse drug reactions: a case/non-case study in Italy. Eur J Clin Pharmacol 2007 Jan; 63 (1): 73-9
    • (2007) Eur J Clin Pharmacol , vol.63 , Issue.1 , pp. 73-79
    • Motola, D.1    Vargiu, A.2    Leone, R.3
  • 55
    • 34548060926 scopus 로고    scopus 로고
    • Telithromycin use and spontaneous reports of hepatotoxicity
    • Dore DD, DiBello JR, Lapane KL. Telithromycin use and spontaneous reports of hepatotoxicity. Drug Saf 2007; 30 (8): 697-703
    • (2007) Drug Saf , vol.30 , Issue.8 , pp. 697-703
    • Dore, D.D.1    DiBello, J.R.2    Lapane, K.L.3
  • 56
    • 35748932057 scopus 로고    scopus 로고
    • Safety concerns with fluoroquinolones
    • Nov;
    • Mehlhorn AJ, Brown DA. Safety concerns with fluoroquinolones. Ann Pharmacother 2007 Nov; 41 (11): 1859-66
    • (2007) Ann Pharmacother , vol.41 , Issue.11 , pp. 1859-1866
    • Mehlhorn, A.J.1    Brown, D.A.2
  • 57
    • 0032762387 scopus 로고    scopus 로고
    • Proteoglycan and collagen biochemical variations during fluoroquinolone-induced chondrotoxicity in mice
    • Dec;
    • Simonin MA, Gegout-Pottie P, Minn A, et al. Proteoglycan and collagen biochemical variations during fluoroquinolone-induced chondrotoxicity in mice. Antimicrob Agents Chemother 1999 Dec; 43 (12): 2915-21
    • (1999) Antimicrob Agents Chemother , vol.43 , Issue.12 , pp. 2915-2921
    • Simonin, M.A.1    Gegout-Pottie, P.2    Minn, A.3
  • 58
    • 28544443116 scopus 로고    scopus 로고
    • Contrasting effects of fluoroquinolone antibiotics on the expression of the collagenases, matrix metalloproteinases (MMP)-1 and -13, in human tendon-derived cells
    • Corps AN, Dec;
    • Corps AN, Harrall RL, Curry VA, et al. Contrasting effects of fluoroquinolone antibiotics on the expression of the collagenases, matrix metalloproteinases (MMP)-1 and -13, in human tendon-derived cells. Rheumatology (Oxford) 2005 Dec; 44 (12): 1514-7
    • (2005) Rheumatology (Oxford) , vol.44 , Issue.12 , pp. 1514-1517
    • Harrall, R.L.1    Curry, V.A.2
  • 59
    • 0029150454 scopus 로고
    • Magnesium deficiency induces joint cartilage lesions in juvenile rats which are identical to quinolone-induced arthropathy
    • Sep;
    • Stahlmann R, Forster C, Shakibaei M, et al. Magnesium deficiency induces joint cartilage lesions in juvenile rats which are identical to quinolone-induced arthropathy. Antimicrob Agents Chemother 1995 Sep; 39 (9): 2013-8
    • (1995) Antimicrob Agents Chemother , vol.39 , Issue.9 , pp. 2013-2018
    • Stahlmann, R.1    Forster, C.2    Shakibaei, M.3
  • 60
    • 60249094709 scopus 로고    scopus 로고
    • Quinolone-induced arthropathy: An update focusing on new mechanistic and clinical data
    • Mar;
    • Sendzik J, Lode H, Stahlmann R. Quinolone-induced arthropathy: an update focusing on new mechanistic and clinical data. Int J Antimicrob Agents. 2009 Mar; 33 (3): 194-200
    • (2009) Int J Antimicrob Agents , vol.33 , Issue.3 , pp. 194-200
    • Sendzik, J.1    Lode, H.2    Stahlmann, R.3
  • 61
    • 0037792114 scopus 로고    scopus 로고
    • Fluoroquinolone-associated tendinopathy: A critical review of the literature
    • Jun 1;
    • Khaliq Y, Zhanel GG. Fluoroquinolone-associated tendinopathy: a critical review of the literature. Clin Infect Dis 2003 Jun 1; 36 (11): 1404-10
    • (2003) Clin Infect Dis , vol.36 , Issue.11 , pp. 1404-1410
    • Khaliq, Y.1    Zhanel, G.G.2
  • 62
    • 20944449837 scopus 로고    scopus 로고
    • Fluoroquinolones and tendon disorders
    • Mar;
    • Melhus A. Fluoroquinolones and tendon disorders. Expert Opin Drug Saf 2005 Mar; 4 (2): 299-309
    • (2005) Expert Opin Drug Saf , vol.4 , Issue.2 , pp. 299-309
    • Melhus, A.1
  • 63
    • 0035159603 scopus 로고    scopus 로고
    • Quinoloneassociated tendonitis: A potential problem in COPD?
    • Jul;
    • Butler MW, Griffin JF, Quinlan WR, et al. Quinoloneassociated tendonitis: a potential problem in COPD? Ir J Med Sci 2001 Jul; 170 (3): 198-9
    • (2001) Ir J Med Sci , vol.170 , Issue.3 , pp. 198-199
    • Butler, M.W.1    Griffin, J.F.2    Quinlan, W.R.3
  • 64
    • 2642542404 scopus 로고    scopus 로고
    • Recurrent tendinitis after treatment with two different fluoroquinolones
    • Burkhardt O, Kohnlein T, Pap T, et al. Recurrent tendinitis after treatment with two different fluoroquinolones. Scand J Infect Dis 2004; 36 (4): 315-6
    • (2004) Scand J Infect Dis , vol.36 , Issue.4 , pp. 315-316
    • Burkhardt, O.1    Kohnlein, T.2    Pap, T.3
  • 65
    • 3042580678 scopus 로고    scopus 로고
    • Fluoroquinolone toxicity: A review of classand agent-specific adverse effects
    • Iannini PB. Fluoroquinolone toxicity: a review of classand agent-specific adverse effects. Drug Benefit Trends 2004; Suppl.: 34-41
    • (2004) Drug Benefit Trends , Issue.SUPPL. , pp. 34-41
    • Iannini, P.B.1
  • 66
    • 1642378789 scopus 로고    scopus 로고
    • Short-term and long-term outcomes of moxifloxacin compared to standard antibiotic treatment in acute exacerbations of chronic bronchitis
    • Mar;
    • Wilson R, Allegra L, Huchon G, et al. Short-term and long-term outcomes of moxifloxacin compared to standard antibiotic treatment in acute exacerbations of chronic bronchitis. Chest 2004 Mar; 125 (3): 953-64
    • (2004) Chest , vol.125 , Issue.3 , pp. 953-964
    • Wilson, R.1    Allegra, L.2    Huchon, G.3
  • 67
    • 34447508333 scopus 로고    scopus 로고
    • Adverse drug reactions related to amoxicillin alone and in association with clavulanic acid: Data from spontaneous reporting in Italy
    • Jul;
    • Salvo F, Polimeni G, Moretti U, et al. Adverse drug reactions related to amoxicillin alone and in association with clavulanic acid: data from spontaneous reporting in Italy. J Antimicrob Chemother 2007 Jul; 60 (1): 121-6
    • (2007) J Antimicrob Chemother , vol.60 , Issue.1 , pp. 121-126
    • Salvo, F.1    Polimeni, G.2    Moretti, U.3
  • 68
    • 33646839952 scopus 로고    scopus 로고
    • Adverse cutaneous reactions and drugs: A focus on antimicrobials
    • Apr;
    • Iannini P, Mandell L, Felmingham J, et al. Adverse cutaneous reactions and drugs: a focus on antimicrobials. J Chemother 2006 Apr; 18 (2): 127-39
    • (2006) J Chemother , vol.18 , Issue.2 , pp. 127-139
    • Iannini, P.1    Mandell, L.2    Felmingham, J.3
  • 69
    • 10344234269 scopus 로고    scopus 로고
    • Moxifloxacinassociated drug hypersensitivity syndrome with toxic epidermal necrolysis and fulminant hepatic failure
    • Dec;
    • Nori S, Nebesio C, Brashear R, et al. Moxifloxacinassociated drug hypersensitivity syndrome with toxic epidermal necrolysis and fulminant hepatic failure. Arch Dermatol 2004 Dec; 140 (12): 1537-8
    • (2004) Arch Dermatol , vol.140 , Issue.12 , pp. 1537-1538
    • Nori, S.1    Nebesio, C.2    Brashear, R.3
  • 70
    • 35348873346 scopus 로고    scopus 로고
    • Risk factors for acute generalized exanthematous pustulosis (AGEP)- results of a multinational case-control study (Euro- SCAR)
    • Nov;
    • Sidoroff A, Dunant A, Viboud C, et al. Risk factors for acute generalized exanthematous pustulosis (AGEP)- results of a multinational case-control study (Euro- SCAR). Br J Dermatol 2007 Nov; 157 (5): 989-96
    • (2007) Br J Dermatol , vol.157 , Issue.5 , pp. 989-996
    • Sidoroff, A.1    Dunant, A.2    Viboud, C.3
  • 71
    • 34548068295 scopus 로고    scopus 로고
    • Incidence of allergic reactions associated with antibacterial use in a large, managed care organisation
    • Johannes CB, Ziyadeh N, Seeger JD, et al. Incidence of allergic reactions associated with antibacterial use in a large, managed care organisation. Drug Saf 2007; 30 (8): 705-13
    • (2007) Drug Saf , vol.30 , Issue.8 , pp. 705-713
    • Johannes, C.B.1    Ziyadeh, N.2    Seeger, J.D.3
  • 72
    • 0035031194 scopus 로고    scopus 로고
    • Adverse reactions to fluoroquinolones. an overview on mechanistic aspects
    • Mar;
    • De Sarro A, De Sarro G. Adverse reactions to fluoroquinolones. an overview on mechanistic aspects. Curr Med Chem 2001 Mar; 8 (4): 371-84
    • (2001) Curr Med Chem , vol.8 , Issue.4 , pp. 371-384
    • De Sarro, A.1    De Sarro, G.2
  • 73
    • 21844444791 scopus 로고    scopus 로고
    • Antimicrobial safety: Focus on fluoroquinolones
    • Jul 15;
    • Owens Jr RC, Ambrose PG. Antimicrobial safety: focus on fluoroquinolones. Clin Infect Dis 2005 Jul 15; 41 Suppl. 2: S144-57
    • (2005) Clin Infect Dis , vol.41 , Issue.SUPPL. 2
    • Owens Jr, R.C.1    Ambrose, P.G.2
  • 74
    • 65949104736 scopus 로고    scopus 로고
    • US Cipro- package insert [online, Available from URL:, Accessed 2009 Mar 18
    • US Cipro- package insert [online]. Available from URL: http://www.univgraph.com/bayer/inserts/ciprotab.pdf [Accessed 2009 Mar 18]
  • 75
    • 65949123945 scopus 로고    scopus 로고
    • US Factive- package insert [online, Available from URL:, Accessed 2009 Mar 18
    • US Factive- package insert [online]. Available from URL: http://www.factive.com/pdf/prescribing-info.pdf [Accessed 2009 Mar 18]
  • 76
    • 0034800656 scopus 로고    scopus 로고
    • Seizures associated with fluoroquinolones
    • Oct;
    • Kushner JM, Peckman HJ, Snyder CR. Seizures associated with fluoroquinolones. Ann Pharmacother 2001 Oct; 35 (10): 1194-8
    • (2001) Ann Pharmacother , vol.35 , Issue.10 , pp. 1194-1198
    • Kushner, J.M.1    Peckman, H.J.2    Snyder, C.R.3
  • 77
    • 0033010428 scopus 로고    scopus 로고
    • Fluoroquinolone toxicity profiles: A review focusing on newer agents
    • Feb;
    • Lipsky BA, Baker CA. Fluoroquinolone toxicity profiles: a review focusing on newer agents. Clin Infect Dis 1999 Feb; 28 (2): 352-64
    • (1999) Clin Infect Dis , vol.28 , Issue.2 , pp. 352-364
    • Lipsky, B.A.1    Baker, C.A.2
  • 78
    • 0032812691 scopus 로고    scopus 로고
    • Potential interactions of the extended-spectrum fluoroquinolones with the CNS
    • Aug;
    • Lode H. Potential interactions of the extended-spectrum fluoroquinolones with the CNS. Drug Saf 1999 Aug; 21 (2): 123-35
    • (1999) Drug Saf , vol.21 , Issue.2 , pp. 123-135
    • Lode, H.1
  • 79
    • 0034786745 scopus 로고    scopus 로고
    • Fluoroquinolone adverse effects and drug interactions
    • Oct;
    • Fish DN. Fluoroquinolone adverse effects and drug interactions. Pharmacotherapy 2001 Oct; 21 (10 Pt 2): 253-72S
    • (2001) Pharmacotherapy , vol.21 , Issue.10 PART 2
    • Fish, D.N.1
  • 80
    • 0032711437 scopus 로고    scopus 로고
    • Comparative tolerability of the newer fluoroquinolone antibacterials
    • Nov;
    • Ball P, Mandell L, Niki Y, et al. Comparative tolerability of the newer fluoroquinolone antibacterials. Drug Saf 1999 Nov; 21 (5): 407-21
    • (1999) Drug Saf , vol.21 , Issue.5 , pp. 407-421
    • Ball, P.1    Mandell, L.2    Niki, Y.3
  • 81
    • 0344015783 scopus 로고    scopus 로고
    • Determination of the excitatory potencies of fluoroquinolones in the central nervous system by an in vitro model
    • Jul;
    • Schmuck G, Schurmann A, Schluter G. Determination of the excitatory potencies of fluoroquinolones in the central nervous system by an in vitro model. Antimicrob Agents Chemother 1998 Jul; 42 (7): 1831-6
    • (1998) Antimicrob Agents Chemother , vol.42 , Issue.7 , pp. 1831-1836
    • Schmuck, G.1    Schurmann, A.2    Schluter, G.3
  • 82
    • 48149091056 scopus 로고    scopus 로고
    • Cellular basis of drug-induced torsades de pointes
    • Aug;
    • Roden DM. Cellular basis of drug-induced torsades de pointes. Br J Pharmacol 2008 Aug; 154 (7): 1502-7
    • (2008) Br J Pharmacol , vol.154 , Issue.7 , pp. 1502-1507
    • Roden, D.M.1
  • 83
    • 0036089685 scopus 로고    scopus 로고
    • Blockade of human cardiac potassium channel human ether-a-go-go-related gene (HERG) by macrolide antibiotics
    • Jul;
    • Volberg WA, Koci BJ, Su W, et al. Blockade of human cardiac potassium channel human ether-a-go-go-related gene (HERG) by macrolide antibiotics. J Pharmacol Exp Ther 2002 Jul; 302 (1): 320-7
    • (2002) J Pharmacol Exp Ther , vol.302 , Issue.1 , pp. 320-327
    • Volberg, W.A.1    Koci, B.J.2    Su, W.3
  • 84
    • 33845512496 scopus 로고    scopus 로고
    • Antimicrobial-associated QT interval prolongation: Pointes of interest
    • Dec 15;
    • Owens Jr RC, Nolin TD. Antimicrobial-associated QT interval prolongation: pointes of interest. Clin Infect Dis 2006 Dec 15; 43 (12): 1603-11
    • (2006) Clin Infect Dis , vol.43 , Issue.12 , pp. 1603-1611
    • Owens Jr, R.C.1    Nolin, T.D.2
  • 86
    • 33646581672 scopus 로고    scopus 로고
    • Mechanism of hERG K+ channel blockade by the fluoroquinolone antibiotic moxifloxacin
    • Apr;
    • Alexandrou AJ, Duncan RS, Sullivan A, et al. Mechanism of hERG K+ channel blockade by the fluoroquinolone antibiotic moxifloxacin. Br J Pharmacol 2006 Apr; 147 (8): 905-16
    • (2006) Br J Pharmacol , vol.147 , Issue.8 , pp. 905-916
    • Alexandrou, A.J.1    Duncan, R.S.2    Sullivan, A.3
  • 88
    • 2442562493 scopus 로고    scopus 로고
    • Drugs hERG and sudden death
    • Jun;
    • Brown AM. Drugs hERG and sudden death. Cell Calcium 2004 Jun; 35 (6): 543-7
    • (2004) Cell Calcium , vol.35 , Issue.6 , pp. 543-547
    • Brown, A.M.1
  • 89
    • 0035212983 scopus 로고    scopus 로고
    • Frothingham R. Rates of torsades de pointes associated with ciprofloxacin, ofloxacin, levofloxacin, gatifloxacin, and moxifloxacin. Pharmacotherapy 2001 Dec; 21 (12): 1468-72
    • Frothingham R. Rates of torsades de pointes associated with ciprofloxacin, ofloxacin, levofloxacin, gatifloxacin, and moxifloxacin. Pharmacotherapy 2001 Dec; 21 (12): 1468-72
  • 90
    • 65949096013 scopus 로고    scopus 로고
    • Drug-induced torsades de pointes: Data mining of the public version of the FDA Adverse Event Reporting System (AERS)
    • Epub Apr 8
    • Poluzzi E, Raschi E, Moretti U, et al. Drug-induced torsades de pointes: data mining of the public version of the FDA Adverse Event Reporting System (AERS). Pharmacoepidemiol Drug Saf. Epub 2009 Apr 8
    • (2009) Pharmacoepidemiol Drug Saf
    • Poluzzi, E.1    Raschi, E.2    Moretti, U.3
  • 92
    • 77950267684 scopus 로고    scopus 로고
    • and, online, Available from URL:, Accessed 2009 Mar 18
    • US Food and Drug Administration. Adverse event reporting system (AERS) [online]. Available from URL: http://www.fda.gov/cder/aers/default.htm [Accessed 2009 Mar 18]
    • Adverse event reporting system (AERS)
    • Food, U.S.1
  • 94
    • 33751520003 scopus 로고    scopus 로고
    • Cardiac tolerance of moxifloxacin: Clinical experience froma large observational French study in usual medical practice (IMMEDIAT study)
    • in French, Oct;
    • Veyssier P, Voirot P, Begaud B, et al. Cardiac tolerance of moxifloxacin: clinical experience froma large observational French study in usual medical practice (IMMEDIAT study) [in French]. Med Mal Infect 2006 Oct; 36 (10): 505-12
    • (2006) Med Mal Infect , vol.36 , Issue.10 , pp. 505-512
    • Veyssier, P.1    Voirot, P.2    Begaud, B.3
  • 95
    • 1442306232 scopus 로고    scopus 로고
    • Drug-induced prolongation of the QT interval
    • Mar 4;
    • Roden DM. Drug-induced prolongation of the QT interval. N Engl J Med 2004 Mar 4; 350 (10): 1013-22
    • (2004) N Engl J Med , vol.350 , Issue.10 , pp. 1013-1022
    • Roden, D.M.1
  • 96
    • 2942560844 scopus 로고    scopus 로고
    • QT prolongation with antimicrobial agents: Understanding the significance
    • Owens Jr RC. QT prolongation with antimicrobial agents: understanding the significance. Drugs 2004; 64 (10): 1091-124
    • (2004) Drugs , vol.64 , Issue.10 , pp. 1091-1124
    • Owens Jr, R.C.1
  • 97
    • 0033770638 scopus 로고    scopus 로고
    • Macrolide-induced clinically relevant drug interactions with cytochrome P-450A (CYP) 3A4: An update focused on clarithromycin, azithromycin and dirithromycin
    • Oct;
    • Westphal JF. Macrolide-induced clinically relevant drug interactions with cytochrome P-450A (CYP) 3A4: an update focused on clarithromycin, azithromycin and dirithromycin. Br J Clin Pharmacol 2000 Oct; 50 (4): 285-95
    • (2000) Br J Clin Pharmacol , vol.50 , Issue.4 , pp. 285-295
    • Westphal, J.F.1
  • 98
    • 33645833853 scopus 로고    scopus 로고
    • Drug interactions during therapy with three major groups of antimicrobial agents
    • Apr;
    • Shakeri-Nejad K, Stahlmann R. Drug interactions during therapy with three major groups of antimicrobial agents. Expert Opin Pharmacother 2006 Apr; 7 (6): 639-51
    • (2006) Expert Opin Pharmacother , vol.7 , Issue.6 , pp. 639-651
    • Shakeri-Nejad, K.1    Stahlmann, R.2
  • 99
    • 45849103106 scopus 로고    scopus 로고
    • Proarrhythmic potential of antimicrobial agents
    • Simkó J, Csilek A, Kará szi J, et al. Proarrhythmic potential of antimicrobial agents. Infection 2008; 36: 194-206
    • (2008) Infection , vol.36 , pp. 194-206
    • Simkó, J.1    Csilek, A.2    Kará szi, J.3
  • 100
    • 0038778612 scopus 로고    scopus 로고
    • Adverse drug reactions: Implications for the development of fluoroquinolones
    • May;
    • Ball P. Adverse drug reactions: implications for the development of fluoroquinolones. J Antimicrob Chemother 2003 May; 51 Suppl. 1: 21-7
    • (2003) J Antimicrob Chemother , vol.51 , Issue.SUPPL. 1 , pp. 21-27
    • Ball, P.1
  • 101
    • 33847386304 scopus 로고    scopus 로고
    • Moxifloxacin and torsade de pointes
    • Feb;
    • Dale KM, Lertsburapa K, Kluger J, et al. Moxifloxacin and torsade de pointes. Ann Pharmacother 2007 Feb; 41 (2): 336-40
    • (2007) Ann Pharmacother , vol.41 , Issue.2 , pp. 336-340
    • Dale, K.M.1    Lertsburapa, K.2    Kluger, J.3
  • 102
    • 43249099098 scopus 로고    scopus 로고
    • Torres A, Garau J, Arvis P, et al. Moxifloxacin monotherapy is effective in hospitalized patients with communityacquired pneumonia. The MOTIV study: a randomized clinical trial. Clin Infect Dis 2008May 15; 46 (10): 1499-509
    • Torres A, Garau J, Arvis P, et al. Moxifloxacin monotherapy is effective in hospitalized patients with communityacquired pneumonia. The MOTIV study: a randomized clinical trial. Clin Infect Dis 2008May 15; 46 (10): 1499-509
  • 103
    • 27744540341 scopus 로고    scopus 로고
    • QT prolongation and proarrhythmia by moxifloxacin: Concordance of preclinical models in relation to clinical outcome
    • Nov;
    • Chen X, Cass JD, Bradley JA, et al. QT prolongation and proarrhythmia by moxifloxacin: concordance of preclinical models in relation to clinical outcome. Br J Pharmacol 2005 Nov; 146 (6): 792-9
    • (2005) Br J Pharmacol , vol.146 , Issue.6 , pp. 792-799
    • Chen, X.1    Cass, J.D.2    Bradley, J.A.3
  • 104
    • 49649086486 scopus 로고    scopus 로고
    • Barth J, Jä gerD,MundkowskiR, et al. Single- and multipledose pharmacokinetics of intravenous moxifloxacin in patients with severe hepatic impairment. J Antimicrob Chemother 2008 Sep; 62(3): 575-8
    • Barth J, Jä gerD,MundkowskiR, et al. Single- and multipledose pharmacokinetics of intravenous moxifloxacin in patients with severe hepatic impairment. J Antimicrob Chemother 2008 Sep; 62(3): 575-8
  • 105
    • 48149089999 scopus 로고    scopus 로고
    • Voss MA Literature-based evaluation of four 'hard endpoint' models for assessing drug-induced torsades de pointes liability. Br J Pharmacol 2008; 154: 1523-7
    • Voss MA Literature-based evaluation of four 'hard endpoint' models for assessing drug-induced torsades de pointes liability. Br J Pharmacol 2008; 154: 1523-7
  • 106
    • 33745232368 scopus 로고    scopus 로고
    • Differentiation of arrhythmia risk of the antibacterials moxifloxacin, erythromycin, and telithromycin based on analysis of monophasic action potential duration alternans and cardiac instability
    • Jul;
    • Wisialowski T, Crimin K, Engtrakul J, et al. Differentiation of arrhythmia risk of the antibacterials moxifloxacin, erythromycin, and telithromycin based on analysis of monophasic action potential duration alternans and cardiac instability. J Pharmacol Exp Ther 2006 Jul; 318 (1): 352-9
    • (2006) J Pharmacol Exp Ther , vol.318 , Issue.1 , pp. 352-359
    • Wisialowski, T.1    Crimin, K.2    Engtrakul, J.3
  • 107
    • 18744376412 scopus 로고    scopus 로고
    • Druginduced liver injury: An analysis of 461 incidences submitted to the Spanish registry over a 10-year period
    • Aug;
    • Andrade RJ, Lucena MI, Fernandez MC, et al. Druginduced liver injury: an analysis of 461 incidences submitted to the Spanish registry over a 10-year period. Gastroenterology 2005 Aug; 129 (2): 512-21
    • (2005) Gastroenterology , vol.129 , Issue.2 , pp. 512-521
    • Andrade, R.J.1    Lucena, M.I.2    Fernandez, M.C.3
  • 108
    • 33748909138 scopus 로고    scopus 로고
    • Drug-induced liver injury in a Swedish University hospital out-patient hepatology clinic
    • Oct 15;
    • De Valle MB, Av KV, Alem N, et al. Drug-induced liver injury in a Swedish University hospital out-patient hepatology clinic. Aliment Pharmacol Ther 2006 Oct 15; 24 (8): 1187-95
    • (2006) Aliment Pharmacol Ther , vol.24 , Issue.8 , pp. 1187-1195
    • De Valle, M.B.1    Av, K.V.2    Alem, N.3
  • 109
    • 34249803204 scopus 로고    scopus 로고
    • The impact of eosinophilia and hepatic necrosis on prognosis in patients with drug-induced liver injury
    • Jun 15;
    • Bjornsson E, Kalaitzakis E, Olsson R. The impact of eosinophilia and hepatic necrosis on prognosis in patients with drug-induced liver injury. Aliment Pharmacol Ther 2007 Jun 15; 25 (12): 1411-21
    • (2007) Aliment Pharmacol Ther , vol.25 , Issue.12 , pp. 1411-1421
    • Bjornsson, E.1    Kalaitzakis, E.2    Olsson, R.3
  • 110
    • 33845666885 scopus 로고    scopus 로고
    • Outcome of acute idiosyncratic drug-induced liver injury: Long-term follow-up in a hepatotoxicity registry
    • Dec;
    • Andrade RJ, Lucena MI, Kaplowitz N, et al. Outcome of acute idiosyncratic drug-induced liver injury: long-term follow-up in a hepatotoxicity registry. Hepatology 2006 Dec; 44 (6): 1581-8
    • (2006) Hepatology , vol.44 , Issue.6 , pp. 1581-1588
    • Andrade, R.J.1    Lucena, M.I.2    Kaplowitz, N.3
  • 111
    • 23044473682 scopus 로고    scopus 로고
    • Outcome and prognostic markers in severe drug-induced liver disease
    • Aug;
    • Bjornsson E, Olsson R. Outcome and prognostic markers in severe drug-induced liver disease. Hepatology 2005 Aug; 42 (2): 481-9
    • (2005) Hepatology , vol.42 , Issue.2 , pp. 481-489
    • Bjornsson, E.1    Olsson, R.2
  • 112
    • 34247519288 scopus 로고    scopus 로고
    • Review article: Drug hepatotoxicity
    • May 15;
    • Chang CY, Schiano TD. Review article: drug hepatotoxicity. Aliment Pharmacol Ther 2007 May 15; 25 (10): 1135-51
    • (2007) Aliment Pharmacol Ther , vol.25 , Issue.10 , pp. 1135-1151
    • Chang, C.Y.1    Schiano, T.D.2
  • 113
    • 58149084885 scopus 로고    scopus 로고
    • Antibiotic induced hepatotoxicity: 2008 update. in Spanish
    • Dec;
    • Robles M, Andrade RJ. Antibiotic induced hepatotoxicity: 2008 update. in Spanish. Rev Esp Quimioter 2008 Dec; 21 (4): 224-33
    • (2008) Rev Esp Quimioter , vol.21 , Issue.4 , pp. 224-233
    • Robles, M.1    Andrade, R.J.2
  • 114
    • 33846618263 scopus 로고    scopus 로고
    • Assessment of drug-induced hepatotoxicity in clinical practice: A challenge for gastroenterologists
    • Jan 21;
    • Andrade RJ, Robles M, Fernandez-Castaner A, et al. Assessment of drug-induced hepatotoxicity in clinical practice: a challenge for gastroenterologists. World J Gastroenterol 2007 Jan 21; 13 (3): 329-40
    • (2007) World J Gastroenterol , vol.13 , Issue.3 , pp. 329-340
    • Andrade, R.J.1    Robles, M.2    Fernandez-Castaner, A.3
  • 115
    • 40849111658 scopus 로고    scopus 로고
    • Assessment of drug-induced liver injury in clinical practice
    • Apr;
    • Lucena MI, Garcia-Cortes M, Cueto R, et al. Assessment of drug-induced liver injury in clinical practice. Fundam Clin Pharmacol 2008 Apr; 22 (2): 141-58
    • (2008) Fundam Clin Pharmacol , vol.22 , Issue.2 , pp. 141-158
    • Lucena, M.I.1    Garcia-Cortes, M.2    Cueto, R.3
  • 116
    • 33846251997 scopus 로고    scopus 로고
    • Nathwani RA, Kaplowitz N. Drug hepatotoxicity. Clin Liver Dis 2006 May; 10 (2): 207-17, vii
    • Nathwani RA, Kaplowitz N. Drug hepatotoxicity. Clin Liver Dis 2006 May; 10 (2): 207-17, vii
  • 117
    • 1642356720 scopus 로고    scopus 로고
    • Sepsis and cholestasis
    • Feb;
    • Moseley RH. Sepsis and cholestasis. Clin Liver Dis 2004 Feb; 8 (1): 83-94
    • (2004) Clin Liver Dis , vol.8 , Issue.1 , pp. 83-94
    • Moseley, R.H.1
  • 118
    • 0022387422 scopus 로고
    • Drug interactions and hepatitis produced by some macrolide antibiotics
    • Jul;
    • Pessayre D, Larrey D, Funck-Brentano C, et al. Drug interactions and hepatitis produced by some macrolide antibiotics. J Antimicrob Chemother 1985 Jul; 16 Suppl. A: 181-94
    • (1985) J Antimicrob Chemother , vol.16 , Issue.SUPPL. A , pp. 181-194
    • Pessayre, D.1    Larrey, D.2    Funck-Brentano, C.3
  • 119
    • 0023706706 scopus 로고
    • Inhibition of the mitochondrial oxidation of fatty acids by tetracycline in mice and in man: Possible role in microvesicular steatosis induced by this antibiotic
    • Sep;
    • Freneaux E, Labbe G, Letteron P, et al. Inhibition of the mitochondrial oxidation of fatty acids by tetracycline in mice and in man: possible role in microvesicular steatosis induced by this antibiotic. Hepatology 1988 Sep; 8 (5): 1056-62
    • (1988) Hepatology , vol.8 , Issue.5 , pp. 1056-1062
    • Freneaux, E.1    Labbe, G.2    Letteron, P.3
  • 120
    • 0028217680 scopus 로고
    • Temafloxacin syndrome: Review of 95 cases
    • Jun;
    • Blum MD, Graham DJ, McCloskey CA. Temafloxacin syndrome: review of 95 cases. Clin Infect Dis 1994 Jun; 18 (6): 946-50
    • (1994) Clin Infect Dis , vol.18 , Issue.6 , pp. 946-950
    • Blum, M.D.1    Graham, D.J.2    McCloskey, C.A.3
  • 121
    • 0034598794 scopus 로고    scopus 로고
    • Acute eosinophilic hepatitis from trovafloxacin
    • Feb 3;
    • Chen HJ, Bloch KJ, Maclean JA. Acute eosinophilic hepatitis from trovafloxacin. N Engl J Med 2000 Feb 3; 342 (5): 359-60
    • (2000) N Engl J Med , vol.342 , Issue.5 , pp. 359-360
    • Chen, H.J.1    Bloch, K.J.2    Maclean, J.A.3
  • 122
    • 0034012255 scopus 로고    scopus 로고
    • Trovafloxacininduced acute hepatitis
    • Feb;
    • Lucena MI, Andrade RJ, Rodrigo L, et al. Trovafloxacininduced acute hepatitis. Clin Infect Dis 2000 Feb; 30 (2): 400-1
    • (2000) Clin Infect Dis , vol.30 , Issue.2 , pp. 400-401
    • Lucena, M.I.1    Andrade, R.J.2    Rodrigo, L.3
  • 123
    • 41849119477 scopus 로고    scopus 로고
    • In vitro metabolism of a model cyclopropylamine to reactive intermediate: Insights into trovafloxacin-induced hepatotoxicity
    • Mar;
    • Sun Q, Zhu R, Foss FW, et al. In vitro metabolism of a model cyclopropylamine to reactive intermediate: insights into trovafloxacin-induced hepatotoxicity. Chem Res Toxicol 2008 Mar; 21 (3): 711-9
    • (2008) Chem Res Toxicol , vol.21 , Issue.3 , pp. 711-719
    • Sun, Q.1    Zhu, R.2    Foss, F.W.3
  • 124
    • 58049194180 scopus 로고    scopus 로고
    • Coexposure of mice to trovafloxacin and lipopolysaccharide, a model of idiosyncratic hepatotoxicity, results in a unique gene expression profile and interferon gamma-dependent liver injury
    • Jan;
    • Shaw PJ, Ditewig AC, Waring JF, et al. Coexposure of mice to trovafloxacin and lipopolysaccharide, a model of idiosyncratic hepatotoxicity, results in a unique gene expression profile and interferon gamma-dependent liver injury. Toxicol Sci 2009 Jan; 107 (1): 270-80
    • (2009) Toxicol Sci , vol.107 , Issue.1 , pp. 270-280
    • Shaw, P.J.1    Ditewig, A.C.2    Waring, J.F.3
  • 125
    • 0025227871 scopus 로고
    • Criteria of drug-induced liver disorders: Report of an international consensus meeting
    • Sep;
    • Benichou C. Criteria of drug-induced liver disorders: report of an international consensus meeting. J Hepatol 1990 Sep; 11 (2): 272-6
    • (1990) J Hepatol , vol.11 , Issue.2 , pp. 272-276
    • Benichou, C.1
  • 126
    • 34249821036 scopus 로고    scopus 로고
    • Risk of acute liver injury associated with the use of drugs: A multicentre population survey
    • Jun 15;
    • Sabate M, Ibanez L, Perez E, et al. Risk of acute liver injury associated with the use of drugs: a multicentre population survey. Aliment Pharmacol Ther 2007 Jun 15; 25 (12): 1401-9
    • (2007) Aliment Pharmacol Ther , vol.25 , Issue.12 , pp. 1401-1409
    • Sabate, M.1    Ibanez, L.2    Perez, E.3
  • 127
    • 11144288739 scopus 로고    scopus 로고
    • The burden of acute nonfulminant drug-induced hepatitis in a United States tertiary referral center [corrected]
    • Jan;
    • Galan MV, Potts JA, Silverman AL, et al. The burden of acute nonfulminant drug-induced hepatitis in a United States tertiary referral center [corrected]. J Clin Gastroenterol 2005 Jan; 39 (1): 64-7
    • (2005) J Clin Gastroenterol , vol.39 , Issue.1 , pp. 64-67
    • Galan, M.V.1    Potts, J.A.2    Silverman, A.L.3
  • 128
    • 33645242067 scopus 로고    scopus 로고
    • Suspected drug-induced liver fatalities reported to the WHO database
    • Jan;
    • Bjornsson E, Olsson R. Suspected drug-induced liver fatalities reported to the WHO database. Dig Liver Dis 2006 Jan; 38 (1): 33-8
    • (2006) Dig Liver Dis , vol.38 , Issue.1 , pp. 33-38
    • Bjornsson, E.1    Olsson, R.2
  • 129
    • 0036323793 scopus 로고    scopus 로고
    • Incidence of druginduced hepatic injuries: A French population-based study
    • Aug;
    • Sgro C, Clinard F, Ouazir K, et al. Incidence of druginduced hepatic injuries: a French population-based study. Hepatology 2002 Aug; 36 (2): 451-5
    • (2002) Hepatology , vol.36 , Issue.2 , pp. 451-455
    • Sgro, C.1    Clinard, F.2    Ouazir, K.3
  • 130
    • 3142557936 scopus 로고    scopus 로고
    • Acute and clinically relevant drug-induced liver injury: A population based case-control study
    • Jul;
    • de Abajo FJ, Montero D, Madurga M, et al. Acute and clinically relevant drug-induced liver injury: a population based case-control study. Br J Clin Pharmacol 2004 Jul; 58 (1): 71-80
    • (2004) Br J Clin Pharmacol , vol.58 , Issue.1 , pp. 71-80
    • de Abajo, F.J.1    Montero, D.2    Madurga, M.3
  • 131
    • 15844419903 scopus 로고    scopus 로고
    • Risk of acute liver injury associated with the combination of amoxicillin and clavulanic acid
    • Jun 24;
    • Garcia Rodriguez LA, Stricker BH, Zimmerman HJ. Risk of acute liver injury associated with the combination of amoxicillin and clavulanic acid. Arch Intern Med 1996 Jun 24; 156 (12): 1327-32
    • (1996) Arch Intern Med , vol.156 , Issue.12 , pp. 1327-1332
    • Garcia Rodriguez, L.A.1    Stricker, B.H.2    Zimmerman, H.J.3
  • 132
    • 0027427843 scopus 로고
    • The increased risk of hospitalizations for acute liver injury in a population with exposure to multiple drugs
    • Nov;
    • Perez GS, Garcia Rodriguez LA. The increased risk of hospitalizations for acute liver injury in a population with exposure to multiple drugs. Epidemiology 1993 Nov; 4 (6): 496-501
    • (1993) Epidemiology , vol.4 , Issue.6 , pp. 496-501
    • Perez, G.S.1    Garcia Rodriguez, L.A.2
  • 133
    • 65949084631 scopus 로고    scopus 로고
    • online, Available from URL:, Accessed 2008 Jul 7
    • Rullo B. Hepatic safety experience [online]. Available from URL: http://www.fda.gov/ohrms/dockets/ac/06/slides/2006-4266s1-02-07-%20Ketek-Rullo. pdf [Accessed 2008 Jul 7]
    • Hepatic safety experience
    • Rullo, B.1
  • 134
    • 65949093425 scopus 로고    scopus 로고
    • online, Available from URL:, Accessed 2008 Jul 7
    • Brinker A. Telithromycin-associated hepatotoxicity [online]. Available from URL: http://www.fda.gov/ohrms/dockets/AC/06/slides/2006-4266s1-01-07-FDA- Brinker.ppt [Accessed 2008 Jul 7]
    • Telithromycin-associated hepatotoxicity
    • Brinker, A.1
  • 135
    • 65949088028 scopus 로고    scopus 로고
    • US Augmentin® package insert [online, Available from URL:, Accessed 2008 Jul 7
    • US Augmentin® package insert [online]. Available from URL: http://us.gsk.com/products/assets/us-augmentin.pdf [Accessed 2008 Jul 7]
  • 136
    • 0035893203 scopus 로고    scopus 로고
    • Karim A, Ahmed S, Rossoff LJ, et al. Possible levofloxacin-induced acute hepatocellular injury in a patient with chronic obstructive lung disease. Clin Infect Dis 2001 Dec 15; 33 (12): 2088-90
    • Karim A, Ahmed S, Rossoff LJ, et al. Possible levofloxacin-induced acute hepatocellular injury in a patient with chronic obstructive lung disease. Clin Infect Dis 2001 Dec 15; 33 (12): 2088-90
  • 137
    • 25844486048 scopus 로고    scopus 로고
    • Levofloxacin-induced acute fulminant hepatic failure in a patient with chronic hepatitis B infection
    • Oct;
    • Coban S, Ceydilek B, Ekiz F, et al. Levofloxacin-induced acute fulminant hepatic failure in a patient with chronic hepatitis B infection. Ann Pharmacother 2005 Oct; 39 (10): 1737-40
    • (2005) Ann Pharmacother , vol.39 , Issue.10 , pp. 1737-1740
    • Coban, S.1    Ceydilek, B.2    Ekiz, F.3
  • 138
    • 0037387817 scopus 로고    scopus 로고
    • Acute hepatitis associated with oral levofloxacin therapy in a hemodialysis patient
    • Apr 1;
    • Schwalm JD, Lee CH. Acute hepatitis associated with oral levofloxacin therapy in a hemodialysis patient. CMAJ 2003 Apr 1; 168 (7): 847-8
    • (2003) CMAJ , vol.168 , Issue.7 , pp. 847-848
    • Schwalm, J.D.1    Lee, C.H.2
  • 139
    • 0036318352 scopus 로고    scopus 로고
    • Moxifloxacininduced acute liver injury
    • Jul;
    • Soto S, Lopez-Roses L, Avila S, et al. Moxifloxacininduced acute liver injury. Am J Gastroenterol 2002 Jul; 97 (7): 1853-4
    • (2002) Am J Gastroenterol , vol.97 , Issue.7 , pp. 1853-1854
    • Soto, S.1    Lopez-Roses, L.2    Avila, S.3
  • 141
    • 0030052616 scopus 로고    scopus 로고
    • Increase in insulin release from rat pancreatic islets by quinolone antibiotics
    • Jan;
    • Maeda N, Tamagawa T, Niki I, et al. Increase in insulin release from rat pancreatic islets by quinolone antibiotics. Br J Pharmacol 1996 Jan; 117 (2): 372-6
    • (1996) Br J Pharmacol , vol.117 , Issue.2 , pp. 372-376
    • Maeda, N.1    Tamagawa, T.2    Niki, I.3
  • 142
    • 41149144595 scopus 로고    scopus 로고
    • Dysglycaemias and fluoroquinolones
    • Lewis RJ, Mohr III JF. Dysglycaemias and fluoroquinolones. Drug Saf 2008; 31 (4): 283-92
    • (2008) Drug Saf , vol.31 , Issue.4 , pp. 283-292
    • Lewis, R.J.1    Mohr III, J.F.2
  • 143
    • 0043156252 scopus 로고    scopus 로고
    • Kagansky N, Levy S, Rimon E, et al. Hypoglycemia as a predictor of mortality in hospitalized elderly patients. Arch Intern Med 2003 Aug 11; 163 (15): 1825-9
    • Kagansky N, Levy S, Rimon E, et al. Hypoglycemia as a predictor of mortality in hospitalized elderly patients. Arch Intern Med 2003 Aug 11; 163 (15): 1825-9
  • 144
    • 26044475604 scopus 로고    scopus 로고
    • Fluoroquinolone-associated dysglycemias: A tale of two toxicities
    • Owens Jr RC. Fluoroquinolone-associated dysglycemias: a tale of two toxicities. Pharmacotherapy 2005Oct; 25 (10): 1291-5
    • Pharmacotherapy 2005Oct , vol.25 , Issue.10 , pp. 1291-1295
    • Owens Jr, R.C.1
  • 145
    • 0031857558 scopus 로고    scopus 로고
    • Hypoglycemia in hospitalized nondiabetic older patients
    • Aug;
    • Shilo S, Berezovsky S, Friedlander Y, et al. Hypoglycemia in hospitalized nondiabetic older patients. J Am Geriatr Soc 1998 Aug; 46 (8): 978-82
    • (1998) J Am Geriatr Soc , vol.46 , Issue.8 , pp. 978-982
    • Shilo, S.1    Berezovsky, S.2    Friedlander, Y.3
  • 146
    • 26044472341 scopus 로고    scopus 로고
    • Mohr JF, McKinnon PS, Peymann PJ, et al. A retrospective, comparative evaluation of dysglycemias in hospitalized patients receiving gatifloxacin, levofloxacin, ciprofloxacin, or ceftriaxone. Pharmacotherapy 2005 Oct; 25 (10): 1303-9
    • Mohr JF, McKinnon PS, Peymann PJ, et al. A retrospective, comparative evaluation of dysglycemias in hospitalized patients receiving gatifloxacin, levofloxacin, ciprofloxacin, or ceftriaxone. Pharmacotherapy 2005 Oct; 25 (10): 1303-9
  • 147
    • 26044471430 scopus 로고    scopus 로고
    • Hypoglycemia in inpatients after gatifloxacin or levofloxacin therapy: Nested case-control study
    • Oct;
    • Graumlich JF, Habis S, Avelino RR, Gaynes RP, et al. Hypoglycemia in inpatients after gatifloxacin or levofloxacin therapy: nested case-control study. Pharmacotherapy 2005 Oct; 25 (10): 1296-302
    • (2005) Pharmacotherapy , vol.25 , Issue.10 , pp. 1296-1302
    • Graumlich, J.F.1    Habis, S.2    Avelino, R.R.3    Gaynes, R.P.4
  • 148
    • 39749120072 scopus 로고    scopus 로고
    • Antimicrobial-associated risk factors for Clostridium difficile infection
    • Jan 15;
    • Owens Jr RC, Donskey CJ, Gaynes RP, et al. Antimicrobial-associated risk factors for Clostridium difficile infection. Clin Infect Dis 2008 Jan 15; 46 Suppl. 1: S19-31
    • (2008) Clin Infect Dis , vol.46 , Issue.SUPPL. 1
    • Owens Jr, R.C.1    Donskey, C.J.2    Gaynes, R.P.3
  • 149
    • 35348853726 scopus 로고    scopus 로고
    • Fluoroquinolone use and risk factors for Clostridium difficile associated disease within a Veterans Administration health care system
    • Nov 1;
    • McFarland LV, Clarridge JE, Beneda HW, et al. Fluoroquinolone use and risk factors for Clostridium difficile associated disease within a Veterans Administration health care system. Clin Infect Dis 2007 Nov 1; 45 (9): 1141-51
    • (2007) Clin Infect Dis , vol.45 , Issue.9 , pp. 1141-1151
    • McFarland, L.V.1    Clarridge, J.E.2    Beneda, H.W.3
  • 150
    • 27444437759 scopus 로고    scopus 로고
    • Emergence of fluoroquinolones as the predominant risk factor for Clostridium difficile-associated diarrhea: A cohort study during an epidemic in Quebec
    • Nov 1;
    • Pepin J, Saheb N, Coulombe MA, et al. Emergence of fluoroquinolones as the predominant risk factor for Clostridium difficile-associated diarrhea: a cohort study during an epidemic in Quebec. Clin Infect Dis 2005 Nov 1; 41 (9): 1254-60
    • (2005) Clin Infect Dis , vol.41 , Issue.9 , pp. 1254-1260
    • Pepin, J.1    Saheb, N.2    Coulombe, M.A.3
  • 151
    • 1442302900 scopus 로고    scopus 로고
    • Outbreak of Clostridium difficile infection in a long-term care facility: Association with gatifloxacin use
    • Mar 1;
    • Gaynes R, Rimland D, Killum E, et al. Outbreak of Clostridium difficile infection in a long-term care facility: association with gatifloxacin use. Clin Infect Dis 2004 Mar 1; 38 (5): 640-5
    • (2004) Clin Infect Dis , vol.38 , Issue.5 , pp. 640-645
    • Gaynes, R.1    Rimland, D.2    Killum, E.3
  • 152
    • 33748689373 scopus 로고    scopus 로고
    • Are broad-spectrum fluoroquinolones more likely to cause Clostridium difficile-associated disease?
    • Sep;
    • Dhalla IA, Mamdani MM, Simor AE, et al. Are broad-spectrum fluoroquinolones more likely to cause Clostridium difficile-associated disease? Antimicrob Agents Chemother 2006 Sep; 50 (9): 3216-9
    • (2006) Antimicrob Agents Chemother , vol.50 , Issue.9 , pp. 3216-3219
    • Dhalla, I.A.1    Mamdani, M.M.2    Simor, A.E.3
  • 153
    • 33847727550 scopus 로고    scopus 로고
    • Moxifloxacin therapy as a risk factor for Clostridium difficile-associated disease during an outbreak: Attempts to control a new epidemic strain
    • Feb;
    • Biller P, Shank B, Lind L, et al. Moxifloxacin therapy as a risk factor for Clostridium difficile-associated disease during an outbreak: attempts to control a new epidemic strain. Infect Control Hosp Epidemiol 2007 Feb; 28 (2): 198-201
    • (2007) Infect Control Hosp Epidemiol , vol.28 , Issue.2 , pp. 198-201
    • Biller, P.1    Shank, B.2    Lind, L.3
  • 154
    • 58849103516 scopus 로고    scopus 로고
    • What have we learned about antimicrobial use and the risks for Clostridium difficile-associated diarrhoea?
    • Feb;
    • Blondeau JM. What have we learned about antimicrobial use and the risks for Clostridium difficile-associated diarrhoea? J Antimicrob Chemother 2009 Feb; 63 (2): 238-42
    • (2009) J Antimicrob Chemother , vol.63 , Issue.2 , pp. 238-242
    • Blondeau, J.M.1
  • 155
    • 65949120129 scopus 로고    scopus 로고
    • online, Available from URL:, Accessed 2008 Jul 9
    • Generali J. Black box warnings from the FDA [online]. Available from URL: http://www.formularyproductions.com/blackbox/ [Accessed 2008 Jul 9]
    • Black box warnings from the FDA
    • Generali, J.1
  • 156
    • 65949105197 scopus 로고    scopus 로고
    • US Ceftin® package insert [online, Available from URL:, Accessed 2008 Jul 9
    • US Ceftin® package insert [online]. Available from URL: http://us.gsk.com/products/assets/us-ceftintablets.pdf [Accessed 2008 Jul 9]
  • 157
    • 65949110776 scopus 로고    scopus 로고
    • US Biaxin® package insert [online, Available from URL:, Accessed 2008 Jul 9
    • US Biaxin® package insert [online]. Available from URL: http://www.rxabbott.com/pdf/biapi.pdf [Accessed 2008 Jul 9]
  • 158
    • 65949101151 scopus 로고    scopus 로고
    • US Zithromax® package insert [online, Available from URL:, Accessed 2008 Jul 9
    • US Zithromax® package insert [online]. Available from URL: http://media.pfizer.com/files/products/uspi-zithromax.pdf [Accessed 2008 Jul 9]
  • 159
    • 65949087591 scopus 로고    scopus 로고
    • US Ketek® package insert [online, Available from URL:, Accessed 2008 Jul 9
    • US Ketek® package insert [online]. Available from URL: http://products.sanofi-aventis.us/ketek/Ketek.pdf [Accessed 2008 Jul 9]
  • 160
    • 34347237593 scopus 로고    scopus 로고
    • The safety profile of moxifloxacin and other fluoroquinolones in special patient populations
    • Jun;
    • Iannini PB. The safety profile of moxifloxacin and other fluoroquinolones in special patient populations. Curr Med Res Opin 2007 Jun; 23 (6): 1403-13
    • (2007) Curr Med Res Opin , vol.23 , Issue.6 , pp. 1403-1413
    • Iannini, P.B.1
  • 161
    • 33645562990 scopus 로고    scopus 로고
    • Antibiotic treatment and factors influencing short and long term outcomes of acute exacerbations of chronic bronchitis
    • Apr;
    • Wilson R, Jones P, Schaberg T, et al. Antibiotic treatment and factors influencing short and long term outcomes of acute exacerbations of chronic bronchitis. Thorax 2006 Apr; 61 (4): 337-42
    • (2006) Thorax , vol.61 , Issue.4 , pp. 337-342
    • Wilson, R.1    Jones, P.2    Schaberg, T.3
  • 162
    • 33645751070 scopus 로고    scopus 로고
    • Moxifloxacin versus levofloxacin for treatment of acute rhinosinusitis: A retrospective database analysis of treatment duration, outcomes, and charges
    • Feb;
    • Keating KN, Friedman HS, Perfetto EM. Moxifloxacin versus levofloxacin for treatment of acute rhinosinusitis: a retrospective database analysis of treatment duration, outcomes, and charges. Curr Med Res Opin 2006 Feb; 22 (2): 327-33
    • (2006) Curr Med Res Opin , vol.22 , Issue.2 , pp. 327-333
    • Keating, K.N.1    Friedman, H.S.2    Perfetto, E.M.3
  • 164
    • 10444268028 scopus 로고    scopus 로고
    • Economic evaluation of the antibiotic treatment of exacerbations of chronic bronchitis and COPD in primary care
    • Oct;
    • Llor C, Naberan K, Cots JM, et al. Economic evaluation of the antibiotic treatment of exacerbations of chronic bronchitis and COPD in primary care. Int J Clin Pract 2004 Oct; 58 (10): 937-44
    • (2004) Int J Clin Pract , vol.58 , Issue.10 , pp. 937-944
    • Llor, C.1    Naberan, K.2    Cots, J.M.3
  • 165
    • 41149114135 scopus 로고    scopus 로고
    • A cost-effectiveness analysis of antimicrobial treatment of communityacquired pneumonia taking into account resistance in Belgium
    • Mar;
    • Martin M, Moore L, Quilici S, et al. A cost-effectiveness analysis of antimicrobial treatment of communityacquired pneumonia taking into account resistance in Belgium. Curr Med Res Opin 2008 Mar; 24 (3): 737-51
    • (2008) Curr Med Res Opin , vol.24 , Issue.3 , pp. 737-751
    • Martin, M.1    Moore, L.2    Quilici, S.3
  • 166
    • 34447572652 scopus 로고    scopus 로고
    • Cost-effectiveness of empirical prescribing of antimicrobials in communityacquired pneumonia in three countries in the presence of resistance
    • May;
    • Martin M, Quilici S, File T, et al. Cost-effectiveness of empirical prescribing of antimicrobials in communityacquired pneumonia in three countries in the presence of resistance. J Antimicrob Chemother 2007 May; 59 (5): 977-89
    • (2007) J Antimicrob Chemother , vol.59 , Issue.5 , pp. 977-989
    • Martin, M.1    Quilici, S.2    File, T.3
  • 167
    • 0041731574 scopus 로고    scopus 로고
    • An economic evaluation of sequential i.v./po moxifloxacin therapy compared to i.v./po co-amoxiclav with or without clarithromycin in the treatment of community-acquired pneumonia
    • Aug;
    • Drummond MF, Becker DL, Hux M, et al. An economic evaluation of sequential i.v./po moxifloxacin therapy compared to i.v./po co-amoxiclav with or without clarithromycin in the treatment of community-acquired pneumonia. Chest 2003 Aug; 124 (2): 526-35
    • (2003) Chest , vol.124 , Issue.2 , pp. 526-535
    • Drummond, M.F.1    Becker, D.L.2    Hux, M.3
  • 168
    • 27144503793 scopus 로고    scopus 로고
    • Cost analyses of community-acquired pneumonia from the hospital perspective
    • Oct;
    • Bauer TT, Welte T, Ernen C, et al. Cost analyses of community-acquired pneumonia from the hospital perspective. Chest 2005 Oct; 128 (4): 2238-46
    • (2005) Chest , vol.128 , Issue.4 , pp. 2238-2246
    • Bauer, T.T.1    Welte, T.2    Ernen, C.3
  • 169
    • 21844439468 scopus 로고    scopus 로고
    • Pharmacoeconomic considerations associated with the use of intravenous-to-oral moxifloxacin for community-acquired pneumonia
    • Jul 15;
    • Davis SL, Delgado Jr G, McKinnon PS. Pharmacoeconomic considerations associated with the use of intravenous-to-oral moxifloxacin for community-acquired pneumonia. Clin Infect Dis 2005 Jul 15; 41 Suppl. 2: S136-43
    • (2005) Clin Infect Dis , vol.41 , Issue.SUPPL. 2
    • Davis, S.L.1    Delgado Jr, G.2    McKinnon, P.S.3
  • 170
    • 48049111154 scopus 로고    scopus 로고
    • A pharmacoeconomic review of the management of respiratory tract infections with moxifloxacin
    • Jul;
    • Simoens S, Decramer M. A pharmacoeconomic review of the management of respiratory tract infections with moxifloxacin. Expert Opin Pharmacother 2008 Jul; 9 (10): 1735-44
    • (2008) Expert Opin Pharmacother , vol.9 , Issue.10 , pp. 1735-1744
    • Simoens, S.1    Decramer, M.2


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